keyword
MENU ▼
Read by QxMD icon Read
search

Samer

keyword
https://www.readbyqxmd.com/read/29453701/eanm-guidelines-for-radionuclide-therapy-of-bone-metastases-with-beta-emitting-radionuclides
#1
Daria Handkiewicz-Junak, Thorsten D Poeppel, Lisa Bodei, Cumali Aktolun, Samer Ezziddin, Francesco Giammarile, Roberto C Delgado-Bolton, Michael Gabriel
The skeleton is the most common metastatic site in patients with advanced cancer. Pain is a major healthcare problem in patients with bone metastases. Bone-seeking radionuclides that selectively accumulate in the bone are used to treat cancer-induced bone pain and to prolong survival in selected groups of cancer patients. The goals of these guidelines are to assist nuclear medicine practitioners in: (a) evaluating patients who might be candidates for radionuclide treatment of bone metastases using beta-emitting radionuclides such as strontium-89 ( 89 Sr), samarium-153 ( 153 Sm) lexidronam ( 153 Sm-EDTMP), and phosphorus-32 ( 32 P) sodium phosphate; (b) performing the treatments; and...
February 16, 2018: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/29453687/impact-of-boosted-antiretroviral-therapy-on-the-pharmacokinetics-and-efficacy-of-clopidogrel-and-prasugrel-active-metabolites
#2
Niloufar Marsousi, Youssef Daali, Pierre Fontana, Jean-Luc Reny, Virginie Ancrenaz-Sirot, Alexandra Calmy, Serge Rudaz, Jules Alexandre Desmeules, Caroline Flora Samer
BACKGROUND AND OBJECTIVES: Prasugrel and clopidogrel are inhibitors of the ADP-P 2 Y 12 platelet receptor used in acute coronary syndrome patients. They require bioactivation via isoenzymes such as cytochrome P450 (CYP) 3A4, CYP2C19 and CYP2B6. Ritonavir and cobicistat are potent CYP3A inhibitors, prescribed as pharmacokinetic (PK) enhancers in the treatment of human immunodeficiency virus (HIV) infection. METHODS: In this study, the impact of boosted antiretroviral therapies (ARTs) on the PK of clopidogrel and prasugrel active metabolites (AMs), and on the efficacy of prasugrel and clopidogrel, were evaluated in a randomized crossover clinical trial...
February 16, 2018: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/29452691/recurrent-cardiovascular-events-in-survivors-of-myocardial-infarction-with-st-segment-elevation-from-the-ami-quebec-study
#3
Thao Huynh, Martine Montigny, Umair Iftikhar, Roxanne Gagnon, Mark Eisenberg, Claude Lauzon, Samer Mansour, Stephane Rinfret, Marc Afilalo, Michel Nguyen, Simon Kouz, Jean-Pierre Déry, Richard Harvey, Robert De LaRocheliere, Bernard Cantin, Eerick Schampaert, Jean-Claude Tardif
The characteristics and predictors of long-term recurrent ischemic cardiovascular events (RICEs) after myocardial infarction with ST-segment elevation (STEMI) have not yet been clarified. We aimed to characterize the 10-year incidence, types, and predictors of RICE. We obtained 10-year follow-up of STEMI survivors at 17 Quebec hospitals in Canada (the AMI-QUEBEC Study) in 2003. There were 858 patients; mean age was 60 years and 73% were male. The majority of patients receive reperfusion therapy; 53.3% and 39...
January 31, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29448240/evaluation-of-production-cross-sections-for-186-re-theranostic-radionuclide-via-charged-particle-induced-reactions-on-tungsten
#4
Samer K I Ali, Mayeen Uddin Khandaker, H A Kassim
186 Re (T 1/2 = 89.24 h, [Formula: see text] 346.7 keV, [Formula: see text] ), an intense beta-emitter shows great potential to be used as an active material in therapeutic radiopharmaceuticals due to its suitable physico-chemical properties. 186 Re can be produced in several ways, however charged-particle induced reactions show to be promising towards no carrier added production. In this work, production cross-sections of 186 Re were evaluated following the light-charged particle induced reactions on tungsten...
January 31, 2018: Applied Radiation and Isotopes
https://www.readbyqxmd.com/read/29444793/isolated-bladder-schwannoma-a-rare-presentation
#5
Samer Jallad, Samir Ghani, Mohammad Ali Omar, Hanif Motiwala
Bladder schwannoma is a rare tumour arising from Schwann cells in nerve sheaths. It is usually more common in patients diagnosed with neurofibromatosis. However, isolated cases of urinary bladder schwannoma is incredibly rare, attributing to <0.1% of bladder tumours. A literature review and analysis revealed that it presents in adulthood, is mostly symptomatic and diagnosis is established histologically. We report a case of isolated bladder schwannoma in 25 year-old female who presented with dyspareunia.
February 14, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29437981/second-generation-hydrogel-coils-for-the-endovascular-treatment-of-intracranial-aneurysms-a-randomized-controlled-trial
#6
Christian A Taschner, René Chapot, Vincent Costalat, Paolo Machi, Patrick Courthéoux, Xavier Barreau, Jérôme Berge, Laurent Pierot, Krzysztof Kadziolka, Betty Jean, Raphaël Blanc, Alessandra Biondi, Hervé Brunel, Sophie Gallas, Ansgar Berlis, Denis Herbreteau, Joachim Berkefeld, Horst Urbach, Samer Elsheikh, Jens Fiehler, Hubert Desal, Erika Graf, Alain Bonafé
BACKGROUND AND PURPOSE: Endovascular embolization of intracranial aneurysms with hydrogel-coated coils lowers the risk of major recurrence, but technical limitations (coil stiffness and time restriction for placement) have prevented their wider clinical use. We aimed to assess the efficacy of softer, second-generation hydrogel coils. METHODS: A randomized controlled trial was conducted at 22 centers in France and Germany. Patients aged 18 to 75 years with untreated ruptured or unruptured intracranial aneurysms measuring 4 to 12 mm in diameter were eligible and randomized (1:1 using a web-based system, stratified by rupture status) to coiling with either second-generation hydrogel coils or bare platinum coils...
February 6, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29433992/changes-in-statin-prescription-patterns-in-patients-admitted-to-an-australian-geriatric-subacute-unit
#7
Samer Noaman, Omar Al-Mukhtar, Sheri Abramovic, Hanin Mohammed, Cheng Yee Goh, Claire Long, Christopher Neil, Edward Janus, Nicholas Cox, William Chan
BACKGROUND: Assessment of demographic and clinical factors influencing the decision of statin discontinuation in the elderly population admitted to subacute geriatric unit. The aim of this study is to assess the clinical factors impacting the decision-making process of statin discontinuation in the elderly. METHODS: We retrospectively assessed changes in statin discontinuation and prescription among patients (≥60 years old) discharged from a geriatric evaluation and management unit by reviewing hospital digital medical records at Western Health - The Williamstown Hospital over a 12-month period from 4 February 2012 until 4 February 2013 inclusive...
January 31, 2018: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/29426618/thyroid-lobectomy-is-not-sufficient-for-t2-papillary-thyroid-cancers
#8
Samer R Rajjoub, Huan Yan, Natalie A Calcatera, Kristine Kuchta, Chi-Hsiung E Wang, Waseem Lutfi, Tricia A Moo-Young, David J Winchester, Richard A Prinz
BACKGROUND: Histologic subtypes of papillary thyroid cancer affect prognosis. The objective of this study was to examine whether survival is affected by extent of surgery for conventional versus follicular-variant papillary thyroid cancer when stratified by tumor size. METHODS: Using the National Cancer Data Base, we evaluated 33,816 adults undergoing surgery for papillary thyroid cancer from 2004 to 2008 for 1.0-3.9 cm tumors and clinically negative lymph nodes...
February 7, 2018: Surgery
https://www.readbyqxmd.com/read/29423487/the-emergence-of-aqueous-chemiluminescence-new-promising-class-of-phenoxy-1-2-dioxetane-luminophores
#9
Samer Gnaim, Ori Green, Doron Shabat
The majority of known chemiluminescent compounds produce light through oxidation-dependent mechanisms. The unique notion of triggering chemiluminescence by a chemical reaction other than oxidation was first introduced by Schaap in 1987 with the development of chemically and enzymatically activated phenoxy-dioxetanes. Such dioxetanes are distinctive among chemiluminescent molecules since the oxidized high-energy species, the dioxetane, is stable for years at room temperature. Light emission is selectively activated by deprotection of the phenol-protecting group...
February 9, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29422089/cement-pulmonary-embolism-as-a-complication-of-percutaneous-vertebroplasty-in-cancer-patients
#10
Asem Mansour, Nayef Abdel-Razeq, Hussein Abuali, Mohammad Makoseh, Nouran Shaikh-Salem, Kamelah Abushalha, Samer Salah
BACKGROUND: Vertebroplasty is a minimally invasive procedure commonly performed for vertebral compression fractures secondary to osteoporosis or malignancy. Leakage of bone cement into the paravertebral venous system and cement pulmonary embolism (cPE) are well described, mostly in patients with osteoporosis. Little is known about the clinical sequelae and outcomes in cancer patients. In this study, we report our experience with cPE following vertebroplasty performed in cancer patients...
February 8, 2018: Cancer Imaging: the Official Publication of the International Cancer Imaging Society
https://www.readbyqxmd.com/read/29417247/predicting-conversion-from-laparoscopic-to-open-cholecystectomy-a-single-institution-retrospective-study
#11
Samer Al Masri, Yaser Shaib, Mostapha Edelbi, Hani Tamim, Faek Jamali, Nicholas Batley, Walid Faraj, Ali Hallal
BACKGROUND: Laparoscopic cholecystectomy (LC) is the standard surgical treatment for benign gallbladder disease. Nevertheless, conversion to open cholecystectomy (OC) is needed in some cases. The aim of this study is to calculate our institutional conversion rate and to identify the variables that are implicated in increasing the risk of conversion (LC-OC). MATERIALS AND METHODS: We carried out a retrospective study of all cases of LC performed at the American University of Beirut Medical Center between 2000 and 2015...
February 7, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29396238/lag-3-in-non-small-cell-lung-cancer-expression-in-primary-tumors-and-metastatic-lymph-nodes-is-associated-with-improved-survival
#12
Sigurd M Hald, Mehrdad Rakaee, Inigo Martinez, Elin Richardsen, Samer Al-Saad, Erna-Elise Paulsen, Egil Støre Blix, Thomas Kilvaer, Sigve Andersen, Lill-Tove Busund, Roy M Bremnes, Tom Donnem
BACKGROUND: Lymphocyte activation gene-3 (LAG-3) is an immune checkpoint receptor and a putative therapeutic target in non-small-cell lung cancer (NSCLC). We explored the prognostic effect of LAG-3+ tumor-infiltrating lymphocytes (TILs) in primary tumors and metastatic lymph nodes in NSCLC and its potential for inclusion in an immunoscore, supplementing the TNM classification. MATERIALS AND METHODS: Primary tumor tissue from 553 stage I-IIIB NSCLC patients and 143 corresponding metastatic lymph nodes were collected...
December 11, 2017: Clinical Lung Cancer
https://www.readbyqxmd.com/read/29395416/insights-into-insulin-resistance-lifestyle-and-anthropometric-measures-of-patients-with-prior-colorectal-cancer-compared-to-controls-a-national-health-and-nutrition-examination-survey-nhanes-study
#13
Kenneth Obi, Mitchell Ramsey, Alice Hinton, Peter Stanich, Darrell M Gray, Somashekar Krishna, Samer El-Dika, Hisham Hussan
BACKGROUND: Insulin resistance (IR) increases the risk of index colorectal cancer (CRC) development. Limited data exist on IR values, lifestyle, and anthropometric alterations of patients after CRC diagnosis, a population at high risk for CRC recurrence. METHODS: This is a retrospective cohort study using the National Health and Nutrition Examination Survey (NHANES), 1999-2010. We identified patients with and without prior CRC above age 50. Our outcomes were lifestyle, anthropometric measures, and IR measured using the triglyceride to high-density lipoprotein ratio and the homeostasis model assessment IR...
January 5, 2018: Current Problems in Cancer
https://www.readbyqxmd.com/read/29392099/improving-c1-c2-complex-fusion-rates-an-alternate-approach
#14
REVIEW
Samer S Ghostine, Paul E Kaloostian, Christ Ordookhanian, Sean Kaloostian, Parham Zarrini, Terrence Kim, Stephen Scibelli, Scott J Clark-Schoeb, Srinath Samudrala, Carl Lauryssen, Amandip S Gill, Patrick J Johnson
The surgical repair of atlantoaxial instabilities (AAI) presents complex and unique challenges, originating from abnormalities and/or trauma within the junction regions of the C1-C2 atlas-axis, to surgeons. When this region is destabilized, surgical fusion becomes of key importance in order to prevent spinal cord injury. Several techniques can be utilized to provide for the adequate fusion of the atlantoaxial construct. Nevertheless, many individuals have less than ideal rates of fusion, below 35%-40%, which also involves the C2 nerve root being sacrificed...
November 29, 2017: Curēus
https://www.readbyqxmd.com/read/29387150/population-genomics-analyses-of-european-ibex-species-show-lower-diversity-and-higher-inbreeding-in-reintroduced-populations
#15
Christine Grossen, Iris Biebach, Samer Angelone-Alasaad, Lukas F Keller, Daniel Croll
Restoration of lost species ranges to their native distribution is key for the survival of endangered species. However, reintroductions often fail and long-term genetic consequences are poorly understood. Alpine ibex (Capra ibex) are wild goats that recovered from <100 individuals to ~50,000 within a century by population reintroductions. We analyzed the population genomic consequences of the Alpine ibex reintroduction strategy. We genotyped 101,822 genomewide single nucleotide polymorphism loci in 173 Alpine ibex, the closely related Iberian ibex (Capra pyrenaica) and domestic goat (Capra hircus)...
February 2018: Evolutionary Applications
https://www.readbyqxmd.com/read/29370995/american-society-for-metabolic-and-bariatric-surgery-estimation-of-metabolic-and-bariatric-procedures-performed-in-the-united-states-in-2016
#16
Wayne J English, Eric J DeMaria, Stacy A Brethauer, Samer G Mattar, Raul J Rosenthal, John M Morton
BACKGROUND: Bariatric surgery, despite being the most successful long-lasting treatment for morbid obesity, remains underused as only approximately 1% of all patients who qualify for surgery actually undergo surgery. To determine if patients in need are receiving appropriate therapy, the American Society for Metabolic and Bariatric Surgery created a Numbers Taskforce to specify annual rate of use for obesity treatment interventions. OBJECTIVES: The objective of this study was to determine metabolic and bariatric procedure trends since 2011 and to provide the best estimate of the number of procedures performed in the United States in 2016...
December 16, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29363415/no-increased-risk-of-posttransplant-lymphoproliferative-disorder-following-alemtuzumab-induction-in-kidney-transplant
#17
Madeleine Oliver, Graham Mitro, Patrick Tenbrink, Samer Alharthi, Nastassja Bedford, Jinling Wu, Amira Gohara, Matthew Jordan, Cassandra Zaremba, Michael Rees, Jorge Ortiz
OBJECTIVES: Posttransplant lymphoproliferative disorder is a known complication of solid-organ transplant. The use of depleting induction agents has demonstrated varying associations with incidence of posttransplant lymphoproliferative disorder. Alemtuzumab, a depleting induction agent for kidney transplant patients, has shown promising results in reducing the risk of acute rejection and graft loss in the first year. Its unique mechanism of depleting both T-cell and B-cell populations may be beneficial in preventing the occurrence of posttransplant lymphoproliferative disorder...
January 22, 2018: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/29353274/postoperative-immobilization-following-occipitocervical-fusion-in-the-pediatric-population-outcome-evaluation-and-review-of-literature
#18
Alexandre R Pingarilho, Paulo M Porto de Melo, Samer K Elbabaa
The scientific literature does not have a consensus about the role and method of postoperative immobilization after occipitocervical fusion in the pediatric population. The primary goal of this study is to review the medical literature and evaluate different immobilization methods and their impact on fusion, following the surgical management of craniocervical instability in children. It started with an extensive research of randomized controlled trials, series of cases and case reports, describing occipitocervical junction pathologies, clinical, epidemiological characteristics, and treatment...
January 20, 2018: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29351638/a-rare-case-of-granulomatosis-with-polyangiitis-induced-burnout-cardiomyopathy-role-of-combined-viability-and-metabolic-imaging
#19
Majid Asawaeer, Samer Sayyed, Yiannis S Chatzizisis
No abstract text is available yet for this article.
January 16, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29344383/prognosis-of-patients-with-secondary-mitral-regurgitation-and-reduced-ejection-fraction
#20
Samer Mowakeaa, Aeshita Dwivedi, Jason R Grossman, Gaurav Parikh, Zelmira Curillova, Krishna G Aragam, Sammy Elmariah, Scott Kinlay, Jayashri Aragam
Objective: The impact of the severity of secondary mitral regurgitation (MR) on the risk of death and heart failure (HF) hospitalisations in patients with reduced left ventricular (LV) systolic function is poorly defined. The study sought to identify the incremental risk of secondary MR in patients with reduced LV systolic function. Methods: We studied 615 consecutive patients with LV ejection fraction ≤35% by transthoracic echocardiography at a single medical centre...
2018: Open Heart
keyword
keyword
5275
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"