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https://www.readbyqxmd.com/read/29331850/attentional-biases-in-patients-suffering-from-unipolar-depression-results-of-a-dot-probe-task-investigation
#1
Wolfgang Trapp, Christoph Kalzendorf, Corinna Baum, Göran Hajak, Stefan Lautenbacher
Cognitive models of depression emphasize the relevance of cognitive biases for development, onset and maintenance of major depressive disorder (MDD). Attentional biases consisting of increased attention to negative, mood congruent stimuli and reduced attention to positive, mood-incongruent stimuli are postulated but have rarely been tested for early attentional processing. Furthermore, the role of concurrent depressive mood as a moderating factor has not been studied to date. Participants comprised 30 patients suffering from MDD and 30 healthy control subjects...
January 4, 2018: Psychiatry Research
https://www.readbyqxmd.com/read/29238336/combination-of-classifiers-identifies-fungal-specific-activation-of-lysosome-genes-in-human-monocytes
#2
João P Leonor Fernandes Saraiva, Cristina Zubiria-Barrera, Tilman E Klassert, Maximilian J Lautenbach, Markus Blaess, Ralf A Claus, Hortense Slevogt, Rainer König
Blood stream infections can be caused by several pathogens such as viruses, fungi and bacteria and can cause severe clinical complications including sepsis. Delivery of appropriate and quick treatment is mandatory. However, it requires a rapid identification of the invading pathogen. The current gold standard for pathogen identification relies on blood cultures and these methods require a long time to gain the needed diagnosis. The use of in situ experiments attempts to identify pathogen specific immune responses but these often lead to heterogeneous biomarkers due to the high variability in methods and materials used...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/29190320/comparing-the-outcomes-of-adults-with-enterobacteriaceae-bacteremia-receiving-short-course-versus-prolonged-course-antibiotic-therapy-in-a-multicenter-propensity-score-matched-cohort
#3
Darunee Chotiprasitsakul, Jennifer H Han, Sara E Cosgrove, Anthony D Harris, Ebbing Lautenbach, Anna T Conley, Pam Tolomeo, Jacqueleen Wise, Pranita D Tamma
Background: The recommended duration of antibiotic treatment for Enterobacteriaceae bloodstream infections is 7-14 days. We compared the outcomes of patients receiving short-course (6-10 days) vs prolonged-course (11-16 days) antibiotic therapy for Enterobacteriaceae bacteremia. Methods: A retrospective cohort study was conducted at 3 medical centers and included patients with monomicrobial Enterobacteriaceae bacteremia treated with in vitro active therapy in the range of 6-16 days between 2008 and 2014...
October 8, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29117619/development-of-obesity-associated-comorbidities-post-bariatric-surgery-with-a-special-focus-on-diabetes-remission-and-short-term-relapse
#4
Nina Riedel, Anne Lautenbach, Jan Wilhelm Wienecke, Oliver Mann, Jörg Flitsch, Jens Aberle
Purpose The purpose of this study is to study a heterogeneous group of obese patients undergoing Bariatric surgery(BS) and its impact on glycemic control. Secondary endpoints include changes in lipid profile and albuminuria. BS has shown to effectively reduce body-weight. However, the impact on obesity-related comorbidities varies strongly between individuals. Especially postoperative short- and long-term improvement of Diabetes is an active area of investigation. Methods We conducted a retrospective analysis from baseline to 24 months post bariatric surgery in our interdisciplinary obesity outpatient-clinic...
November 8, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/29075677/phonetic-characteristics-of-vocalizations-during-pain
#5
Stefan Lautenbacher, Melissa Salinas-Ranneberg, Oliver Niebuhr, Miriam Kunz
INTRODUCTION AND OBJECTIVES: There have, yet, been only few attempts to phonetically characterize the vocalizations of pain, although there is wide agreement that moaning, groaning, or other nonverbal utterance can be indicative of pain. We studied the production of vowels "u," "a," "i", and "schwa" (central vowel, sounding like a darker "e" as in hesitations like "ehm")-as experimental approximations to natural vocalizations. METHODS: In 50 students vowel production and self-report ratings were assessed during painful and nonpainful heat stimulation (hot water immersion) as well as during baseline (no-stimulation)...
May 2017: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/29037288/global-asthma-burden-and-poverty-in-the-twenty-first-century
#6
Laura Lautenbacher, Matthew S Perzanowski
No abstract text is available yet for this article.
November 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28968345/sleep-and-pain-are-definitely-coupled-but-how-tight-is-this-coupling
#7
Stefan Lautenbacher
No abstract text is available yet for this article.
September 29, 2017: Pain
https://www.readbyqxmd.com/read/28949844/when-bins-blur-patient-perspectives-on-categories-of-results-from-clinical-whole-genome-sequencing
#8
Leila Jamal, Jill O Robinson, Kurt D Christensen, Jennifer Blumenthal-Barby, Melody J Slashinski, Denise Lautenbach Perry, Jason L Vassy, Julia Wycliff, Robert C Green, Amy L McGuire
BACKGROUND: Clinical genome and exome sequencing (CGES) is being used in an expanding range of clinical settings. Most approaches to offering patients choices about learning CGES results classify results according to expert definitions of clinical actionability. Little is known about how patients conceptualize different categories of CGES results. METHODS: The MedSeq Project is a randomized controlled trial studying the use of whole-genome sequencing (WGS) in primary care and cardiology...
April 2017: AJOB Empirical Bioethics
https://www.readbyqxmd.com/read/28940665/prediction-of-persistent-post-operative-pain-pain-specific-psychological-variables-compared-with-acute-post-operative-pain-and-general-psychological-variables
#9
C Horn-Hofmann, J Scheel, V Dimova, A Parthum, R Carbon, N Griessinger, R Sittl, S Lautenbacher
BACKGROUND: Psychological variables and acute post-operative pain are of proven relevance for the prediction of persistent post-operative pain. We aimed at investigating whether pain-specific psychological variables like pain catastrophizing add to the predictive power of acute pain and more general psychological variables like depression. METHODS: In all, 104 young male patients undergoing thoracic surgery for pectus excavatum correction were studied on the pre-operative day (T0) and 1 week (T1) and 3 months (T2) after surgery...
September 20, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28939607/multidrug-and-mupirocin-resistance-in-environmental-methicillin-resistant-staphylococcus-aureus-mrsa-collected-from-the-homes-of-people-diagnosed-with-a-community-onset-co-mrsa-infection
#10
J H Shahbazian, P D Hahn, S Ludwig, J Ferguson, P Baron, A Christ, K Spicer, P Tolomeo, A M Torrie, W B Bilker, V C Cluzet, B Hu, K Julian, I Nachamkin, S C Rankin, D O Morris, E Lautenbach, M F Davis
Patients with community-onset methicillin-resistant Staphylococcus aureus (CO-MRSA) infections contribute to MRSA contamination of the home environment, and may be re-exposed to MRSA strains from this reservoir. This study evaluates One Health risk factors that focus on the relationship between humans, animals and the environment for increased prevalence of multiple antimicrobial resistant MRSA in the home environment. During a trial of patients with CO-MRSA infection, MRSA was isolated from the household environment at baseline and three months later, following randomization of patients and household members to mupirocin-based decolonization therapy or education control...
September 22, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28938042/infectious-diseases-careers-in-healthcare-epidemiology-and-antimicrobial-stewardship
#11
Ebbing Lautenbach
No abstract text is available yet for this article.
September 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28899563/treating-osteomyelitis-of-major-limb-amputations-with-a-modified-lautenbach-technique
#12
Juliet M Clutton, Oliver Donaldson, Anthony Perera, Rhidian Morgan-Jones
INTRODUCTION: Major lower limb amputation significantly increases the energy cost of walking for patients. Complications such as osteomyelitis may require further surgery, and can lead to shortening of the stump. In these cases, the aim should be to treat infection without shortening the limb further. We present a series of patients with established osteomyelitis of the amputation stump, managed using a modified Lautenbach technique. METHOD: Six patients with either above or below knee amputations, in the practice of a single orthopaedic surgeon, were studied...
September 1, 2017: Injury
https://www.readbyqxmd.com/read/28888890/spatial-variations-and-determinants-of-infant-and-under-five-mortality-in-bangladesh
#13
Oliver Gruebner, Mmh Khan, Katrin Burkart, Sven Lautenbach, Tobia Lakes, Alexander Krämer, S V Subramanian, Sandro Galea
Reducing child mortality is a Sustainable Development Goal yet to be achieved by many low-income countries. We applied a subnational and spatial approach based on publicly available datasets and identified permanent insolvency, urbanicity, and malaria endemicity as factors associated with child mortality. We further detected spatial clusters in the east of Bangladesh and noted Sylhet and Jamalpur as those districts that need immediate attention to reduce child mortality. Our approach is transferable to other regions in comparable settings worldwide and may guide future studies to identify subnational regions in need for public health attention...
September 2017: Health & Place
https://www.readbyqxmd.com/read/28814894/startle-modulation-by-heat-pain-with-varying-threat-levels-in-chronic-pain-patients-and-pain-free-controls
#14
C Horn-Hofmann, D Wolf, S Wolff, M Heesen, K Knippenberg-Bigge, P M Lang, S Lautenbacher
BACKGROUND: Empirical evidence suggests that affective responses to pain are changed in chronic pain. The investigation of startle responses to pain might contribute to clarifying whether such alterations also expand to motivational defensive reactions. We aimed at comparing startle responses to tonic heat pain with high threat (HT) or low threat (LT) in patients with chronic musculoskeletal pain and controls. As pain-related anxiety and catastrophizing are typically elevated in chronic pain, we expected to find stronger startle responses in patients specifically under experimental HT...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28806323/interactive-process-of-facial-communication-of-pain
#15
Miriam Kunz, Stefan Lautenbacher
No abstract text is available yet for this article.
August 2, 2017: Pain
https://www.readbyqxmd.com/read/28763294/prevalence-and-causes-of-abnormal-psa-recovery
#16
Noémie Lautenbach, Michael Müntener, Paolo Zanoni, Lanja Saleh, Karim Saba, Martin Umbehr, Srividya Velagapudi, Danielle Hof, Tullio Sulser, Peter J Wild, Arnold von Eckardstein, Cédric Poyet
BACKGROUND: Prostate-specific antigen (PSA) test is of paramount importance as a diagnostic tool for the detection and monitoring of patients with prostate cancer. In the presence of interfering factors such as heterophilic antibodies or anti-PSA antibodies the PSA test can yield significantly falsified results. The prevalence of these factors is unknown. METHODS: We determined the recovery of PSA concentrations diluting patient samples with a standard serum of known PSA concentration...
August 1, 2017: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/28487713/mechanical-harvesting-effectively-controls-young-typha-spp-invasion-and-unmanned-aerial-vehicle-data-enhances-post-treatment-monitoring
#17
Shane C Lishawa, Brendan D Carson, Jodi S Brandt, Jason M Tallant, Nicholas J Reo, Dennis A Albert, Andrew M Monks, Joseph M Lautenbach, Eric Clark
The ecological impacts of invasive plants increase dramatically with time since invasion. Targeting young populations for treatment is therefore an economically and ecologically effective management approach, especially when linked to post-treatment monitoring to evaluate the efficacy of management. However, collecting detailed field-based post-treatment data is prohibitively expensive, typically resulting in inadequate documentation of the ecological effects of invasive plant management. Alternative approaches, such as remote detection with unmanned aerial vehicles (UAV), provide an opportunity to advance the science and practice of restoration ecology...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28486911/editorial-pain-in-dementia-a-distressing-combination-of-several-factors
#18
EDITORIAL
Wilco Achterberg, Stefan Lautenbacher
No abstract text is available yet for this article.
2017: Current Alzheimer Research
https://www.readbyqxmd.com/read/28390438/high-fluoroquinolone-mic-is-associated-with-fluoroquinolone-treatment-failure-in-urinary-tract-infections-caused-by-fluoroquinolone-susceptible-escherichia-coli
#19
Pinyo Rattanaumpawan, Irving Nachamkin, Warren B Bilker, Jason A Roy, Joshua P Metlay, Theoklis E Zaoutis, Ebbing Lautenbach
BACKGROUND: Suboptimal clinical response to fluoroquinolone (FQ) therapy has been clearly documented in patients with Salmonella typhi infection with reduced FQ susceptibility. However, the clinical impact of reduced FQ susceptibility on other infections including E. coli urinary tract infections (UTIs) has never been evaluated. METHODS: We conducted a retrospective cohort study of female patients with fluoroquinolone susceptible E. coli (FQSEC) UTIs who received FQ therapy at outpatient services within University of Pennsylvania Health System, Philadelphia...
April 8, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28350903/advancing-diagnostics-to-address-antibacterial-resistance-the-diagnostics-and-devices-committee-of-the-antibacterial-resistance-leadership-group
#20
Ephraim L Tsalik, Elizabeth Petzold, Barry N Kreiswirth, Robert A Bonomo, Ritu Banerjee, Ebbing Lautenbach, Scott R Evans, Kimberly E Hanson, Jeffrey D Klausner, Robin Patel
Diagnostics are a cornerstone of the practice of infectious diseases. However, various limitations frequently lead to unmet clinical needs. In most other domains, diagnostics focus on narrowly defined questions, provide readily interpretable answers, and use true gold standards for development. In contrast, infectious diseases diagnostics must contend with scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution of existing pathogens and their associated resistance mechanisms, and the absence of gold standards in many situations...
March 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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