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Hyperosmolar hyperglycemic

M Hao, H Y Kuang
No abstract text is available yet for this article.
October 1, 2016: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
Chin-Li Lu, Hsin-Hui Chang, Hua-Fen Chen, Li-Jung Elizabeth Ku, Ya-Hui Chang, Hsiu-Nien Shen, Chung-Yi Li
This study aimed to investigate the association of admissions for diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS) with ambient temperature and season, respectively in patients with diabetes mellitus (DM), after excluding known co-morbidities that predispose onset of acute hyperglycemia events. This was a time series correlation analysis based on medical claims of 40,084 and 33,947 episodes of admission for DKA and HHS, respectively over a 14-year period in Taiwan. These episodes were not accompanied by co-morbidities known to trigger incidence of DKA and HHS...
September 2016: Environment International
Tetsuyuki Yasuda
No abstract text is available yet for this article.
April 2016: Nihon Rinsho. Japanese Journal of Clinical Medicine
Ichiro Hirayama, Takahiro Hiruma, Yoshihiro Ueda, Kent Doi, Susumu Nakajima
No abstract text is available yet for this article.
March 17, 2016: American Journal of Emergency Medicine
Ju Hyun Seo, Jin Ah Kim, Bomi Choi, Kyo Hee Kim, Ha Neul Park, Hannah Seok, Tae Seo Sohn
No abstract text is available yet for this article.
March 10, 2016: Korean Journal of Internal Medicine
Rie Tsutsumi, Mayu Sebe
In this session, we describe the acute phase in patients with metabolic syndrome from two sides; acute disease that occurs higher in patients with metabolic syndrome such as colonary heart disease and stroke, and acute aggravation of diabetes such as diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome. The electrolyte imbalance is frequently detected in critical ill patients. It is reported that the extreme abnormalities of ionized calcium concentrations are independent predictors of mortality. In addition, from clinical database MIMIC-Ⅱ,calcium supplementation improves clinical outcome in intensive care unit patients...
March 2016: Clinical Calcium
Soichiro Shimura, Ken-ichi Tabata, Dai Koguchi, Noriyuki Amano, Morihiro Nishi, Tetsuo Fujita, Kazumasa Matsumoto, Takefumi Satoh, Masatsugu Iwamura
Emphysematous pyelonephritis (EPN) is an acute, severe necrotizing infection of the renal parenchyma and perirenal tissue. A 72-year-old female patient with uncontrolled diabetes mellitus was admitted to a hospital with loss of consciousness and, fever. Laboratory data suggested acute inflammation and hyperosmolar hyperglycemic syndrome. The left EPN was accurately diagnosed after abdominal computed tomographic (CT) scan revealed renal parenchymal gas and fluid within the subcutaneous tissue and mediastinum...
December 2015: Hinyokika Kiyo. Acta Urologica Japonica
Siu Yan Amy Yeung, Sue Lee
No abstract text is available yet for this article.
December 2015: Critical Care Medicine
Ah Hyun Jun, Marina Rabinovich, Shauntrell Johnson
No abstract text is available yet for this article.
December 2015: Critical Care Medicine
Caitlin Schaapveld, Ana Negrete, Joanna Hudson, Jagannath Saikumar, Christopher Finch, Mehmet Kocak, Pan Hu, Megan Van Berkel
No abstract text is available yet for this article.
December 2015: Critical Care Medicine
E Geuna, D Roda, S Rafii, B Jimenez, M Capelan, K Rihawi, F Montemurro, T A Yap, S B Kaye, J S De Bono, L R Molife, U Banerji
BACKGROUND: PI3K-AKT-mTOR inhibitors (PAMi) are promising anticancer treatments. Hyperglycaemia is a mechanism-based toxicity of these agents and is becoming increasingly important with their use in larger numbers of patients. METHODS: Retrospective case-control study comparing incidence and severity of hyperglycaemia (all grades) between a case group of 387 patients treated on 18 phase I clinical trials with PAMi (78 patients with PI3Ki, 138 with mTORi, 144 with AKTi and 27 with PI3K/mTORi) and a control group of 109 patients treated on 10 phase I clinical trials with agents not directly targeting the PAM pathway...
December 1, 2015: British Journal of Cancer
Justin Berk, Raymond Wade, Hatice Duygu Baser, Joaquin Lado
BACKGROUND: This case study features a woman who presented with clinical and laboratory findings consistent with hyperosmolar hyperglycemic non-ketotic syndrome (HHNS), systemic inflammatory response syndrome (SIRS), and non-thyroidal illness syndrome (NTIS) who was noted to have a transient decrease in myocardial function. To our knowledge, this is the first case discussing the overlapping pathophysiological mechanisms could increase susceptibility to SIRS-induced cardiomyopathy. It is imperative that this clinical question be investigated further as such a relationship may have significant clinical implications for prevention and future treatments, particularly in patients similar to the one presented in this clinical case...
2015: BMC Cardiovascular Disorders
Tigestu Alemu Desse, Tesfahun Chanie Eshetie, Esayas Kebede Gudina
BACKGROUND: Diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) commonly known as hyperglycemic emergencies are the two most common life-threatening acute metabolic complications of diabetes. The objective of this study is to assess predictors and treatment outcome of hyperglycemic emergencies (HEs) among diabetic patients admitted to Jimma University Specialized Hospital (JUSH). METHODS: It is a three year retrospective review of medical records of patients admitted with HEs at JUSH...
2015: BMC Research Notes
Alyssa Milano, Ara Tadevosyan, Regina Hart, Anthony Luizza, Mary Eberhardt
No abstract text is available yet for this article.
February 2016: American Journal of Emergency Medicine
Michelle Samson Maust, Russ S Muramatsu, Kathryn Egan, Iqbal Ahmed
No abstract text is available yet for this article.
August 2015: Journal of Clinical Psychopharmacology
Yuan Kao, Chien-Chin Hsu, Shih-Feng Weng, Hung-Jung Lin, Jhi-Joung Wang, Shih-Bin Su, Chien-Cheng Huang, How-Ran Guo
Hyperglycemic crisis episodes (HCEs)-diabetic ketoacidosis and the hyperosmolar hyperglycemic state-are the most serious acute metabolic complications of diabetes. We aimed to investigate the subsequent mortality after HCE in the non-elderly diabetic which is still unclear. This retrospective national population-based cohort study reviewed, in Taiwan's National Health Insurance Research Database, data from 23,079 non-elder patients (≤65 years) with new-onset diabetes between 2000 and 2002: 7693 patients with HCE and 15,386 patients without HCE (1:2)...
January 2016: Endocrine
Jaroslav Rybka, Jerguš Mistrík
The hyperglycemic hyperosmolar state (HHS) is a serious acute complication of diabetes decompensation, especially in type 2 diabetes (T2DM), and with critical prognosis. Primary characteristics of HHS include extreme hyperglycemia, severe dehydration (with prerenal hyperazotaemia), plasma hyperosmolarity, frequent disorders of consciousness, absent or minimum ketoacidosis (with higher values, only found in combined forms). Both DKA and HHS have a common pathogenetic mechanism, but both states are opposite extreme deviations, and the boundaries between them are not entirely clear...
May 2015: Vnitr̆ní Lékar̆ství
Daisuke Wajima, Yuki Ida, Hiroshi Yokota, Ryoma Sasaki, Hiroo Itoh, Hiroyuki Nakase
A 68-year-old female, who suffered from depression, fell down the stairs in her house. She was soon transferred to an accident and emergent ward by an ambulance. Two days later, she was transferred and admitted to our hospital. Next day after admission to our ward, her consciousness level changed for the worse. She developed diabetic ketoacidosis, and was administered insulin during reinfusion. Next day, her diabetic ketoacidosis improved;however, her consciousness level was still poor. Brain magnetic resonance imaging(MRI)showed suspected osmotic myelinolysis lesions in the bilateral cerebellar hemisphere and globus pallidus...
June 2015: No Shinkei Geka. Neurological Surgery
Georgeanna J Klingensmith, Crystal G Connor, Katrina J Ruedy, Roy W Beck, Craig Kollman, Heidi Haro, Jamie R Wood, Joyce M Lee, Steven M Willi, Eda Cengiz, William V Tamborlane
OBJECTIVE: Type 2 diabetes (T2D) in youth is recognized as a pediatric disease, but few reports describe the characteristics during diagnosis. We describe the clinical presentation of 503 youth with T2D. METHODS: The Pediatric Diabetes Consortium (PDC) T2D Clinic Registry enrolled T2D participants from eight pediatric diabetes centers in the USA. Clinical and laboratory characteristics at the time of diagnosis were analyzed. RESULTS: In total 67% presented with symptoms of diabetes and confirming laboratory data, but 33% were identified by testing at risk children, 11% presented with diabetic ketoacidosis (DKA), and 2% with hyperglycemic hyperosmolar state (HHS)...
June 2016: Pediatric Diabetes
Darlene Vigil, Kavitha Ganta, Yijuan Sun, Richard I Dorin, Antonios H Tzamaloukas, Karen S Servilla
A man with past lithium use for more than 15 years, but off lithium for two years and not carrying the diagnosis of diabetes mellitus or nephrogenic diabetes insipidus (NDI), presented with coma and hyperglycemic hyperosmolar state (HHS). Following correction of HHS, he developed persistent hypernatremia accompanied by large volumes of urine with low osmolality and no response to desmopressin injections. Urine osmolality remained < 300 mOsm/kg after injection of vasopressin. Improvement in serum sodium concentration followed the intake of large volumes of water plus administration of amiloride and hydrochlorothiazide...
May 6, 2015: World Journal of Nephrology
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