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Sleep apnea hypopnea syndrome

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https://www.readbyqxmd.com/read/29221777/prevalence-of-sleep-apnea-at-the-acute-phase-of-ischemic-stroke-with%C3%A2-or-without-thrombolysis
#1
Jaana K Huhtakangas, Juha Huhtakangas, Risto Bloigu, Tarja Saaresranta
OBJECTIVE: The aim of the study was to compare the prevalence, type, and severity of sleep apnea during the acute phase of ischemic stroke among patients either receiving or not receiving thrombolysis. METHODS: We recruited 246 consecutive adult ischemic stroke patients. Patients underwent cardiorespiratory sleep study with portable three-channel device during the first 48 h after the symptom onset of ischemic stroke. RESULTS: We enrolled 110 (65...
December 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29217205/increased-urinary-erythropoietin-excretion-in-severe-sleep-apnea-hipoapnea-syndrome-the-effect-of-cpap
#2
Miquel Félez, Nuria Grau, Antonia Ruiz, Encarna Guardiola, Carles Sanjuas, Cristina Estirado, Maribel Navarro-Muñoz, Antoni Pascual, Mauricio Orozco-Levi, Joaquim Gea
INTRODUCTION: Tissue hypoxia stimulates the production of erythropoietin (EPO), the main effect of which is, in turn, to stimulate erythropoiesis. Sleep apnea-hypopnea syndrome (SAHS) is an entity characterized by repeated episodes of hypoxemia during sleep. OBJECTIVE: To analyze whether hypoxemia stimulated increased urinary excretion of EPO, and if so, to evaluate if treatment with continuous positive airway pressure (CPAP) can inhibit this phenomenon. METHODS: We studied 25 subjects with suspected SAHS who underwent a polysomnography study (PSG)...
December 4, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/29204587/transoral-robotic-surgery-vs-endoscopic-partial-midline-glossectomy-for-obstructive-sleep-apnea
#3
David Folk, Mark D'Agostino
Objective: To compare sleep-related outcomes in obstructive sleep apnea hypopnea syndrome (OSAHS) patients following base of tongue resection via robotic surgery and endoscopic midline glossectomy. Methods: This was a retrospective study. A total of 114 robotic and 37 endoscopic midline glossectomy surgeries were performed between July 2010 and April 2015 as part of single or multilevel surgery. Patients were excluded for indications other than sleep apnea or if complete sleep studies were not obtained...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204586/transoral-robotic-surgery-for-obstructive-sleep-apnea-syndrome-principles-and-technique
#4
Claudio Vicini, Filippo Montevecchi, Riccardo Gobbi, Andrea De Vito, Giuseppe Meccariello
Objective: The present study is a review of transoral robotic surgery (TORS) for the treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: The review presents the experience of the robotic center that developed the technique with regards to patient selection, surgical method, and post-operative care. In addition, the review provides results of a systematic review and meta-analysis of the complications and clinical outcomes of TORS when applied in the management of OSAHS...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204444/the-finite-element-simulation-of-the-upper-airway-of-patients-with-moderate-and-severe-obstructive-sleep-apnea-hypopnea-syndrome
#5
Huiping Luo, Austin Scholp, Jack J Jiang
Objectives: To investigate the snoring modes of patients with Obstructive Sleep Apnea Hypopnea Syndrome and to discover the main sources of snoring in soft tissue vibrations. Methods: A three-dimensional finite element model was developed with SolidEdge to simulate the human upper airway. The inherent modal simulation was conducted to obtain the frequencies and the corresponding shapes of the soft tissue vibrations. The respiration process was simulated with the fluid-solid interaction method through ANSYS...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29202829/prevalence-and-risk-factors-of-moderate-to-severe-obstructive-sleep-apnea-syndrome-in-major-depression-a-observational-and-retrospective-study-on-703-subjects
#6
Matthieu Hein, Jean-Pol Lanquart, Gwenolé Loas, Philippe Hubain, Paul Linkowski
BACKGROUND: Several studies have investigated the prevalence and risk factors of depression in subjects with obstructive sleep apnea syndrome. However, few studies have investigated the prevalence and risk factors for obstructive sleep apnea syndrome in major depression. The aim of this study was to examine the prevalence and risk factors of moderate to severe obstructive sleep apnea syndrome in a large sample of individuals with major depression. METHODS: Data from 703 individuals with major depression recruited from the research database of the sleep laboratory of the Erasme Hospital were analysed...
December 4, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29196149/continuous-positive-airway-pressure-treatment-with-nasal-pillows-in-obstructive-sleep-apnea-long-term-effectiveness-and-adherence
#7
Andrea Lanza, Sara Mariani, Maurizio Sommariva, Chiara Campana, Annalisa Rubino, Michele Nichelatti, Paola Proserpio, Lino Nobili
BACKGROUNDS: Mask-related side effects can negatively influence adherence to continuous positive airway pressure (CPAP). Nasal pillows (P) can be an alternative to the standard nasal masks (N), although there are no data about their long-term efficacy. This study aimed to assess long-term effectiveness and adherence to CPAP therapy delivered with nasal pillows in obstructive sleep apnea syndrome (OSAS) patients. METHODS: A retrospective observational design involving a series of consecutive CPAP-naïve patients affected by OSAS...
October 12, 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29190986/the-relationship-between-obstructive-sleep-apnea-and-obesity-hypoventilation-syndrome-a-systematic-review-and-meta-analysis
#8
Chaoling Liu, Mao-Sheng Chen, Hui Yu
Obstructive Sleep Apnea and Obesity Hypoventilation Syndrome are two similar diseases. Obstructive Sleep Apnea has been receiving more and more attention while the diagnostic rate of Obesity Hypoventilation Syndrome is not high. Few studies directly evaluated the relationship between them. We systematically analyzed the relevance of the two diseases. MEDLINE®, EMBASE® and the Cochrane Library were carried out to find studies until May 2017. Pooled mean difference and 95% confidence interval were calculated to evaluate the value of clinical and physiologic variables in the prediction of Obesity Hypoventilation Syndrome...
November 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29190244/evaluation-of-obstructive-sleep-apnea-syndrome-as-a-risk-factor-for-diabetic-macular-edema-in-patients-with-type-ii-diabetes
#9
Anne-Laure Vié, Laurent Kodjikian, Emilie Agard, Nicolas Voirin, Hussam El Chehab, Philippe Denis, Olivier Coste, Corinne Dot
PURPOSE: To evaluate the association between obstructive sleep apnea and diabetic macular edema (DME) in patients with Type II diabetes, using the apnea-hypopnea index and other nocturnal hypoxemia parameters. METHODS: This cross-sectional, case-control study included 99 patients with Type II diabetes: the first group included patients with DME (DME+ group) and the second patients without DME (DME- group). Polysomnography was performed in all patients. The two groups were compared, and the risk factors were studied using logistic regression...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29189544/is-obstructive-sleep-apnea-associated-with-progressive-glaucomatous-optic-neuropathy
#10
Swarup S Swaminathan, Amitabha S Bhakta, Wei Shi, William J Feuer, Alexandre R Abreu, Alejandro D Chediak, David S Greenfield
PURPOSE: To evaluate the relationship between obstructive sleep apnea syndrome (OSAS) and glaucoma progression, and to examine the correlation between OSAS severity and rate of visual field (VF) loss. METHODS: Patients with concurrent diagnoses of open-angle glaucoma and OSAS between 2010-2016 were identified. Enrollment criteria consisted of glaucomatous optic neuropathy and VF loss, ≥5 reliable VFs, ≥2 years of follow-up, and polysomnography (PSG) within 12 months of final VF...
November 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29176802/assessment-of-automated-analysis-of-portable-oximetry-as-a-screening-test-for-moderate-to-severe-sleep-apnea-in-patients-with-chronic-obstructive-pulmonary-disease
#11
Ana M Andrés-Blanco, Daniel Álvarez, Andrea Crespo, C Ainhoa Arroyo, Ana Cerezo-Hernández, Gonzalo C Gutiérrez-Tobal, Roberto Hornero, Félix Del Campo
BACKGROUND: The coexistence of obstructive sleep apnea syndrome (OSAS) and chronic obstructive pulmonary disease (COPD) leads to increased morbidity and mortality. The development of home-based screening tests is essential to expedite diagnosis. Nevertheless, there is still very limited evidence on the effectiveness of portable monitoring to diagnose OSAS in patients with pulmonary comorbidities. OBJECTIVE: To assess the influence of suffering from COPD in the performance of an oximetry-based screening test for moderate-to-severe OSAS, both in the hospital and at home...
2017: PloS One
https://www.readbyqxmd.com/read/29173609/effects-of-patent-foramen-ovale-closure-on-obstructive-sleep-apnea-syndrome-pcosa-study
#12
Stephen P Hoole, Jules Hernández-Sánchez, William R Davies, Duncan C McNab, Patrick A Calvert, Bushra S Rana, Leonard M Shapiro, Michael G Davies
BACKGROUND: Previous studies have shown a higher prevalence of patent foramen ovale (PFO) in patients with obstructive sleep apnea syndrome (OSAS). Right to left shunting through a PFO may be encouraged by the respiratory physiology of OSAS, contributing to the disease pathophysiology. We assessed whether PFO closure would improve respiratory polygraphy parameters compared with baseline measurements in patients with OSAS. METHODS: Twenty-six patients with newly diagnosed OSAS and a moderate-large PFO (prevalence, 18% of 143 patients screened) were referred for PFO closure...
December 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/29167768/correlation-analysis-between-obstructive-sleep-apnea-syndrome-osas-and-heart-rate-variability
#13
Jiayong Xie, Wenjuan Yu, Zongren Wan, Fei Han, Qiaojun Wang, Rui Chen
Background: Heart rate variability (HRV) represents the sympathetic nervous system activity induced by apnea or hypopnea events among OSAS patients. However, few studies have been conducted to clarify the association between HRV parameters and polysomnography (PSG) diagnostic indices. In our study, we postulate that the prevalence of cardiac arrhythmias is associated with OSAS, and HRV parameters may be an effective method for OSAS screening. Methods: Overall, 168 participants had been collected from 2011 to 2016 in the Second Affiliated Hospital of Soochow University...
November 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29164122/changes-in-expression-of-the-clock-gene-in-obstructive-sleep-apnea-syndrome-patients-are-not-reverted-by-continuous-positive-airway-pressure-treatment
#14
Susana Moreira, Raquel Rodrigues, André B Barros, Nadja Pejanovic, Ana Neves-Costa, Dora Pedroso, Cláudia Pereira, Dina Fernandes, João Valença Rodrigues, Cristina Barbara, Luís Ferreira Moita
Purpose: Metabolic syndrome and cardiovascular disease are strongly associated with obstructive sleep apnea syndrome (OSAS), which causes substantial changes to normal circadian physiological functions, including metabolic pathways. Because core clock genes are known to be modulated by sleep/vigilance cycles, we asked whether the expression level of mRNA coding for clock genes is altered in non-treated OSAS patients and if it can be corrected by standard continuous positive airway pressure (CPAP) treatment...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29153557/cardiovascular-risk-and-obesity-in-sleep-apnea-syndrome-assessed-with-the-stop-bang-questionnaire
#15
María Teófila Vicente-Herrero, Luisa Capdevila García, María Del Carmen Bellido Cambrón, María Victoria Ramírez Iñiguez de la Torre, Silvia Lladosa Marco
INTRODUCTION: Sleep disorders include a number of different processes, of which the most prevalent is the sleep apnea-hypopnea syndrome (SAHS). Prevalence of SAHS has increased worldwide, and has a significant social and health impact because of the increased cardiometabolic risk attributed to obesity and the associated metabolic syndrome. MATERIAL AND METHODS: A cross-sectional epidemiological study of 1110 workers from public service companies in the Spanish Mediterranean area (Balearic Islands and Valencian Community) was conducted between January and December 2015...
November 15, 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/29151303/obstructive-sleep-apnea-characteristics-in-patients-with-well-controlled-acromegaly-and-their-compliance-with-positive-airway-pressure-therapy
#16
Mehmet Sezai Taşbakan, Özen Kaçmaz Başoğlu, Ilgın Yıldırım Şimşir, Füsun Saygılı
Background/aim: Acromegaly is often associated with obstructive sleep apnea syndrome (OSAS) with a frequency between 40% and 80%. The aim of the present study was to evaluate the clinical and polysomnographic characteristics of acromegaly patients with sleep apnea symptoms and to identify positive airway pressure (PAP) adherence in acromegaly patients with OSAS diagnosis.Materials and methods: Twenty-eight well-controlled acromegaly patients (17 males, mean age 48.7 ± 10.1 years) with sleep apnea symptoms were included in this prospective study...
November 13, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/29148894/metabolic-profile-in-patients-with-mild-obstructive-sleep-apnea
#17
Luciana Oliveira E Silva, Thais M Guimarães, Gabriela P Luz, Glaury Coelho, Luciana Badke, Ildonete R Almeida, Aline Millani-Carneiro, Sergio Tufik, Lia Bittencourt, Sonia M Togeiro
BACKGROUND: Mild obstructive sleep apnea (OSA) is a highly prevalent disorder in adults. However, it is not clear whether mild OSA has significant metabolic complications. This study examined the prevalence of metabolic syndrome (MS) in patients with mild OSA compared to control group. METHODS: Adults (18-65 years of age) of both genders with a body mass index (BMI) ≤35 kg/m(2) were included. The mild OSA group comprised of patients with an apnea-hypopnea index (AHI) score of ≥5 but ≤15 events/hr of sleep, independent of other symptoms...
November 17, 2017: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29145148/honokiol-protects-pancreatic-%C3%AE-cell-against-high-glucose-and-intermittent-hypoxia-induced-injury-by-activating-nrf2-are-pathway-in-vitro-and-in-vivo
#18
Chen-Guang Li, Chang-Lin Ni, Min Yang, Yun-Zhao Tang, Zhu Li, Yan-Juan Zhu, Zhen-Huan Jiang, Bei Sun, Chun-Jun Li
Obstructive sleep apnea hypopnea syndrome (OSAHS) is associated with glucose intolerance, insulin resistance and type 2 diabetes mellitus (T2DM). Although several studies have revealed that intermittent hypoxia (IH) in OSAHS may further aggravate pancreatic β cell damage and promote the evolution of type 2 diabetes (T2DM) by increasing oxidative stress, the underlying mechanisms are unclear. Honokiol, a potent radical scavenger, has been demonstrated to ameliorate oxidative stress in many cases. The present study aimed to explore the potential mechanism of IH and diabetes synergistically damage and destruct the pancreatic β cell, examine the effects of honokiol on ameliorating pancreatic β cell injury in this context and explore the mechanism of such effects...
November 13, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29141301/-obstructive-sleep-apnea-hypopnea-syndrome-complicated-with-obesity-hypoventilation-syndrome-a-case-report
#19
Z Y Zhang, H H Lu, Q W Li, P Lin
No abstract text is available yet for this article.
November 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29129750/k-complex-morphological-features-in-male-obstructive-sleep-apnea-hypopnea-syndrome-patients
#20
Lin Sun, Xiangmin Zhang, Shaoxiong Huang, Jiuxing Liang, Yuxi Luo
This study characterized the differences in K-complex (KC) morphology features between obstructive sleep apnea-hypopnea syndrome (OSAHS) patients and healthy controls and analyzed the effect of respiratory events on KC morphology. We enrolled 42 male subjects (21 OSAHS patients and 21 age-matched healthy controls) who underwent overnight polysomnography. KCs in stage N2 were manually identified. We found that KCs in healthy controls had larger negative and whole amplitudes, longer durations, and smoother positive waves than OSAHS patients but smaller positive amplitudes...
November 9, 2017: Respiratory Physiology & Neurobiology
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