Miri Dotan, Hannah Blau, Amihood Singer, Patrick Stafler, Dario Prais, Malena Cohen-Cymberknoh, Joel Reiter, Ori Efrati, Adi Dagan, Lea Bentur, Michal Gur, Galit Livnat, Karin Yaacoby-Bianu, Micha Aviram, Inbal Golan Tripto, Ophir Bar-On, Reut Matar, Shani Hagit, Mira Malcov, Gheona Altarescu, Hanna Segev, Baruch Feldman, Eitan Kerem, Meir Mei-Zahav
BACKGROUND: Population genetic carrier screening (PGCS) for cystic fibrosis (CF) has been offered to couples in Israel since 1999 and was included in a fully subsidized national program in 2008. We evaluated the impact of PGCS on CF incidence, genetic and clinical features. METHODS: This was a retrospective national study. Demographic and clinical characteristics of children with CF born in Israel between 2008 and 2018 were obtained from the national CF registry and from patients' medical records...
November 16, 2023: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society