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https://www.readbyqxmd.com/read/28437757/abnormal-loading-and-functional-deficits-are-present-in-both-limbs-before-and-after-unilateral-knee-arthroplasty
#1
A J Metcalfe, C J Stewart, N J Postans, P R Biggs, G M Whatling, C A Holt, A P Roberts
Unilateral knee replacement is often followed by a contralateral replacement in time and the biomechanics of the other knee before and after knee replacement remains poorly understood. The aim of this paper is to distinguish the features of arthritic gait in the affected and unaffected legs relative to a normal population and to assess the objective recovery of gait function post-operatively, with the aim of defining patients at risk of poor post-operative function. Twenty patients with severe knee OA but no pain or deformity in any other lower limb joint were compared to twenty healthy subjects of the same age...
April 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28437619/management-of-posterior-cruciate-ligament-tibial-avulsion-injuries-a-systematic-review
#2
Perry O Hooper, Chris Silko, Tennison L Malcolm, Lutul D Farrow
BACKGROUND: Tibial-sided avulsion injuries of the posterior cruciate ligament (PCL) generally require surgical intervention. No consensus exists concerning the optimal surgical treatment approach for these injuries. PURPOSE: To perform a systematic review investigating the open and arthroscopic surgical treatment modalities, outcomes, and complications of PCL tibial-sided bony avulsions. STUDY DESIGN: Systematic review; Level of evidence, 4...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28437548/arthroscopic-treatment-of-a-displaced-nonunion-of-the-anterior-inferior-iliac-spine-causing-extra-articular-impingement
#3
Motoi Shibahara, Yasuo Ohnishi, Eisaburo Honda, Dean K Matsuda, Soshi Uchida
This report describes a case of nonunion of an anterior inferior iliac spine (AIIS) apophyseal avulsion fracture with resultant subspine impingement combined with symptomatic femoroacetabular impingement (FAI). A 16-year-old male soccer player presented with a 6-month history of right groin pain exacerbated by kicking and running. The patient was diagnosed with a displaced nonunion of the AIIS apophysis avulsion fracture causing secondary extra-articular impingement beyond cam-type FAI by physical examination and radiological findings...
April 24, 2017: Orthopedics
https://www.readbyqxmd.com/read/28437501/pronator-teres-myotendinous-tear
#4
Usama Qayyum, Diego Villacis, Charles M Jobin
Pronator teres muscle strain is a rare sporting injury reported thus far only in cricket and golf players. The injury appears to occur when the sporting club or racket strikes the ground during a forceful swing and causes the elbow to experience an eccentric force during resisted elbow flexion and pronation. On initial presentation, this injury can be mistaken for injury to the medial ulnar collateral ligament, or exacerbation of medial epicondylitis. On examination, bruising and tenderness distal to the elbow over the course of the pronator teres are often present...
March 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28437372/heart-rate-modification-of-cardiac-output-following-cardiac-surgery-the-importance-of-cardiac-time-intervals
#5
Guido Tavazzi, Andy Kontogeorgis, Fabio Guarracino, Niels Bergsland, Ana Martinez-Naharro, John Pepper, Susanna Price
OBJECTIVES: Inadequate cardiac output is associated with a poor outcome following cardiac surgery and is generally modified by the use of positive inotropic agents, volume resuscitation, and pacing. Echocardiography-guided pacemaker optimization is used in the outpatient setting, using different variables including total isovolumic time and the Tei index. We sought to determine the acute impact of heart rate on cardiac electromechanics, cardiac output, and stroke volume in the perioperative setting...
April 21, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28437326/favorable-outcomes-of-preterm-infants-with-parenteral-nutrition-associated-liver-disease-treated-with-intravenous-fish-oil-based-lipid-emulsion
#6
Michael Sorrell, Alvaro Moreira, Kay Green, Rachel Jacob, Robin Tragus, Laura Keller, Amy Quinn, Donald McCurnin, Alice Gong, Abeer El Sakka, Naveen Mittal, Cynthia Blanco
OBJECTIVES: The aim of the study was to determine the acute and long-term outcomes of preterm infants treated with an intravenous fish oil-based lipid emulsion (FishLE) for parenteral nutrition-associated liver disease (PNALD). METHODS: Preterm infants 14 days to 24 months of age with anatomic short gut or severe intestinal dysmotility, serum direct bilirubin ≥4 mg/dL, and requiring >60% calories from parenteral nutrition were eligible. Enrolled infants received 1 g · kg · day of FishLE until resolution of direct hyperbilirubinemia or return of enteral nutrition...
May 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28437294/sleep-detriments-associated-with-quick-returns-in-rotating-shift-work-a-diary-study
#7
Øystein Vedaa, Erik Mørland, Marit Larsen, Anette Harris, Eilin Erevik, Børge Sivertsen, Bjørn Bjorvatn, Siri Waage, Ståle Pallesen
OBJECTIVE: We aimed to compared sleep characteristics associated with quick returns (QRs, <11 hours between shift intervals) with those associated with other common shift transitions. METHODS: Sixty-seven nurses completed a 2-week work and sleep diary (94.0% female, mean age 47.7 years). A multilevel fixed effects model was used to examine the sleep in QRs compared with two consecutive night shifts, two consecutive evening shifts, and two consecutive day shifts, respectively...
April 21, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28437183/first-two-imported-cases-of-zika-virus-infections-in-romania
#8
Simin Aysel Florescu, Ani Ioana Cotar, Corneliu Petru Popescu, Cornelia Svetlana Ceianu, Mihaela Zaharia, Geta Vancea, Daniel Codreanu, Daniela Badescu, Emanoil Ceausu
We report the first two cases of imported Zika virus (ZIKV) infection in Romanian patients returning from areas with ongoing outbreaks and challenges for laboratory diagnostic; first one with a classical pattern of acute flaviviral infection and the second one with an interesting pattern of a secondary flaviviral (ZIKV) infection in a yellow fever-vaccinated child living abroad in an endemic area.
February 23, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28436733/social-and-hospital-costs-of-patients-admitted-to-a-university-hospital-in-brazil-due-to-motorcycle-crashes
#9
Katia Campos Dos Anjos, Marcelo Rosa de Rezende, Rames Mattar Júnior
OBJECTIVE: The present study aimed to investigate the social and hospital costs of patients treated at a public hospital who were motorcycle crash victims. METHOD: This prospective study was on 68 motorcycle riders (drivers or passengers), who were followed up from hospital admission to six months after the crash. A questionnaire covering quantitative and qualitative questions was administered. RESULTS: Motorcycle crash victims were responsible for 12% of the institution's hospital admissions; 54...
February 13, 2017: Traffic Injury Prevention
https://www.readbyqxmd.com/read/28436709/transitioning-from-occupational-therapy-student-to-practicing-occupational-therapist-first-year-of-employment
#10
Randy P McCombie, Meredith E Antanavage
This research examined the transition from occupational therapy student to practicing occupational therapist over the course of one's first year of professional employment, as recalled by a sample of occupational therapists. Surveys were mailed to 500 occupational therapists randomly selected from membership in the American Occupational Therapy Association resulting in 202 returned surveys. Median year of graduation was 1998, ranging from 1967 to 2014. In general, respondents indicated the transition was positive...
April 24, 2017: Occupational Therapy in Health Care
https://www.readbyqxmd.com/read/28436703/in-the-driver-s-seat-development-and-implementation-of-an-e-learning-module-on-return-to-driving-after-stroke
#11
Janet Frith, Isobel Hubbard, Carole James, Helen Warren-Forward
Gaps exist in the knowledge of return-to-driving guidelines, and education is needed for Australian health professionals working in the field of stroke. In this paper, authors evaluate the implementation of an e-learning module. A pre- and post-module knowledge test and survey were used to assess the e-module's success in achieving its learning objectives. Initially, 204 learners completed the module, with 68% of learners scoring 100% in the post-module knowledge test. Only 12 learners completed the survey...
April 24, 2017: Occupational Therapy in Health Care
https://www.readbyqxmd.com/read/28436634/-antiendotoxin-effect-of-jinhuaqingre-capsules
#12
Jiafu Hou, Leilei Wu, Yuting Cai, Changjiu Gao, Jindan An, Zhongcheng Yu
Objective: To investigate the anti-pyretic and anti-endotoxin effect of Chinese herb medicine Jinhuaqingre capsules. Methods: Thirty healthy male New Zealand rabbits with lipopolysaccharide-induced fever were divided into 5 groups (6 rabbits in each): animals in model group were given normal saline by gavage, animals in positive control group were given aspirin (0.2 g/kg), and animals in Jinhuaqingre groups were given Jinhuaqingre capsules 6.0, 3.0 or 1.5 g/kg, respectively. The changes in body temperature of rabbits were observed...
January 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/28436627/-temporal-lobe-epilepsy-and-adult-hippocampal-neurogenesis
#13
Liying Chen, Yi Wang, Zhong Chen
Temporal lobe epilepsy (TLE) is a common and severe neurological disorder which is often intractable. It can not only damage the normal structure and function of hippocampus, but also affect the neurogenesis in dentate gyrus (DG). It is well documented from researches on the animal models of TLE that after a latent period of several days, prolonged seizure activity leads to a dramatic increase in mitotic activity in the hippocampal DG. However, cell proliferation returns to baseline levels within 3-4 weeks after status epilepticus (SE)...
January 25, 2017: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/28436569/association-of-waist-circumference-with-outcomes-in-an-acute-general-surgical-unit
#14
Thomas Ryan, Preet Gosal, Alexa Seal, Joe McGirr, Nicholas Williams
BACKGROUND: Obesity prevalence is increasing in Australia, particularly in non-metropolitan areas. The effect of obesity on acute surgical outcomes is not known. We aimed to record waist circumference (WC) (surrogate for obesity) amongst acute surgical unit (ASU) patients in a New South Wales regional hospital, and compare outcome measures (length of stay (LOS), unplanned return to theatre, readmission rates, intensive care unit (ICU) admission and mortality). METHODS: Retrospective cohort study of 4 months of consecutive ASU admissions, excluding age <16, pregnancy, out-of-area transfer and incomplete data...
April 24, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28436551/genomics-and-metabolomics-of-post-weaning-return-to-estrus
#15
REVIEW
Lea A Rempel, Gary A Rohrer, Danny J Nonneman
The weaning-to-estrus interval is a multifaceted trait that has the potential to substantially improve production efficiency in today's global swine industry, if variation in this measure can be reduced. Systems-biology approaches should help close the knowledge gap and increase selection tools and management strategies - such as gilt development programs, farrowing, and lactation feeding programs - to decrease the weaning-to-estrus interval. Metabolomics, the study of small compounds within biofluids and tissues, provides links between genotype and phenotype...
April 24, 2017: Molecular Reproduction and Development
https://www.readbyqxmd.com/read/28436517/real-time-measurement-of-the-intracellular-ph-of-yeast-cells-during-glucose-metabolism-using-ratiometric-fluorescent-nanosensors
#16
Mohamed M Elsutohy, Veeren M Chauhan, Robert Markus, Mohammed Aref Kyyaly, Saul J B Tendler, Jonathan W Aylott
Intracellular pH is a key parameter that influences many biochemical and metabolic pathways that can also be used as an indirect marker to monitor metabolic and intracellular processes. Herein, we utilise ratiometric fluorescent pH-sensitive nanosensors with an extended dynamic pH range to measure the intracellular pH of yeast (Saccharomyces cerevisiae) during glucose metabolism in real-time. Ratiometric fluorescent pH-sensitive nanosensors consisting of a polyacrylamide nanoparticle matrix covalently linked to two pH-sensitive fluorophores, Oregon green (OG) and 5(6)carboxyfluorescein (FAM), and a reference pH-insensitive fluorophore, 5(6)carboxytetramethylrhodamine (TAMRA), were synthesised...
April 24, 2017: Nanoscale
https://www.readbyqxmd.com/read/28436424/the-immunopathology-of-sepsis-and-potential-therapeutic-targets
#17
REVIEW
Tom van der Poll, Frank L van de Veerdonk, Brendon P Scicluna, Mihai G Netea
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated host response to infection. In sepsis, the immune response that is initiated by an invading pathogen fails to return to homeostasis, thus culminating in a pathological syndrome that is characterized by sustained excessive inflammation and immune suppression. Our understanding of the key mechanisms involved in the pathogenesis of sepsis has increased tremendously, yet this still needs to be translated into novel targeted therapeutic strategies...
April 24, 2017: Nature Reviews. Immunology
https://www.readbyqxmd.com/read/28436350/prevalence-and-risk-factors-for-gastric-ulceration-in-pigs-slaughtered-at-170-kg
#18
F Gottardo, A Scollo, B Contiero, M Bottacini, C Mazzoni, S A Edwards
Oesophago-gastric ulcers (OGU) are a production and welfare problem in pigs. Stomach condition was scored for 22 551 pigs in 228 batches over a 7-month period at an abattoir in Italy processing heavy pigs for ham production. Mild or severe ulceration was observed in 20.7% of pigs, of which 13% had scar tissue. Variation between batches was high (0% to 36% prevalence of severe ulcers) and showed a significant effect of farm of origin (P<0.001). Overnight lairage increased the prevalence of mild ulcers (P<0...
April 24, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28436257/brain-temperature-but-not-core-temperature-increases-during-spreading-depolarizations-in-patients-with-spontaneous-intracerebral-hemorrhage
#19
Alois J Schiefecker, Mario Kofler, Max Gaasch, Ronny Beer, Iris Unterberger, Bettina Pfausler, Gregor Broessner, Peter Lackner, Paul Rhomberg, Elke Gizewski, Werner O Hackl, Miriam Mulino, Martin Ortler, Claudius Thome, Erich Schmutzhard, Raimund Helbok
Spreading depolarizations (SDs) are highly active metabolic events, commonly occur in patients with intracerebral hemorrhage (ICH) and may be triggered by fever. We investigated the dynamics of brain-temperature (Tbrain) and core-temperature (Tcore) relative to the occurrence of SDs. Twenty consecutive comatose ICH patients with multimodal electrocorticograpy (ECoG) and Tbrain monitoring of the perihematomal area were prospectively enrolled. Clusters of SDs were defined as ≥2 SDs/h. Generalized estimating equations were used for statistical calculations...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28436001/gait-instability-in-valproate-treated-patients-call-to-measure-ammonia-levels
#20
S Kipervasser, C E Elger, A D Korczyn, R D Nass, C M Quesada, M Y Neufeld
OBJECTIVE: Hyperammonemia induced by valproate (VPA) treatment may lead to several neurological and systemic symptoms as well as to seizure exacerbation. Gait instability and recurrent falls are rarely mentioned as symptoms, especially not as predominant ones. METHODS: We report five adult patients with frontal lobe epilepsy (FLE) who were treated with VPA and in whom a primary adverse effect was unstable gait and falls. RESULTS: There were four males and one female patients with FLE, 25-42-year-old, three following epilepsy surgery...
April 23, 2017: Acta Neurologica Scandinavica
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