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https://www.readbyqxmd.com/read/28213872/capulavirus-and-grablovirus-two-new-genera-in-the-family-geminiviridae
#1
Arvind Varsani, Philippe Roumagnac, Marc Fuchs, Jesús Navas-Castillo, Enrique Moriones, Ali Idris, Rob W Briddon, Rafael Rivera-Bustamante, F Murilo Zerbini, Darren P Martin
Geminiviruses are plant-infecting single-stranded DNA viruses that occur in most parts of the world. Currently, there are seven genera within the family Geminiviridae (Becurtovirus, Begomovirus, Curtovirus, Eragrovirus, Mastrevirus, Topocuvirus and Turncurtovirus). The rate of discovery of new geminiviruses has increased significantly over the last decade as a result of new molecular tools and approaches (rolling-circle amplification and deep sequencing) that allow for high-throughput workflows. Here, we report the establishment of two new genera: Capulavirus, with four new species (Alfalfa leaf curl virus, Euphorbia caput-medusae latent virus, French bean severe leaf curl virus and Plantago lanceolata latent virus), and Grablovirus, with one new species (Grapevine red blotch virus)...
February 17, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28212682/erratum-to-cause-effect-relations-between-55%C3%A2-kd-soluble-tnf-receptor-concentrations-and-specific-and-unspecific-symptoms-in-a-patient-with-mild-sle-disease-activity-an-exploratory-time-series-analysis-study
#2
Christian Schubert, Julia Haberkorn, Francisco M Ocaña-Peinado, Paul König, Norbert Sepp, Mirjam Schnapka-Köpf, Dietmar Fuchs
No abstract text is available yet for this article.
February 17, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28211966/formation-of-organometallic-intermediate-states-in-on-surface-ullmann-couplings
#3
Dennis Barton, Hong-Ying Gao, Philipp Alexander Held, Armido Studer, Harald Fuchs, Nikos L Doltsinis, Johannes Neugebauer
Possible origins of the formation of organometallic intermediates in on-surface Ullmann couplings have been investigated by surface tunneling microscopy (STM) and density functional theory (DFT) calculations. We consider the case of iodobenzenes on the coinage metals Au, Ag and Cu. We found experimental evidence for the formation of surface vacancies and the presence of metal adatoms in these coupling reactions, which are taken as a hint for the reactive extraction of surface atoms by adsorbates. In a second step, we demonstrate by ab initio molecular dynamics calculations for aryl-iodides on copper that metal atoms can be pulled out of the surface to form metalorganic species...
February 17, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28211878/pre-descemets-endothelial-keratoplasty-the-pdek-clamp-for-successful-pdek
#4
H S Dua, D G Said
PurposeTo design and produce a clamp that enables good handling of donor sclera-corneal disks, allows air to be injected in the corneal stroma and consistently provides pre-Descemets endothelial keratoplasty (PDEK) tissue by creation of a type-1 big bubble (BB) avoiding a type-2BB by shutting the fenestrations in the periphery of the pre-Descemets layer and preventing escape of air.Patients and methodsA clamp with spring loaded handles attached to two rings of 9 mm diameter and 1 mm width with a side port for insertion of a needle for air injection was designed and produced...
February 17, 2017: Eye
https://www.readbyqxmd.com/read/28208900/fuchs-heterochromic-iridocylitis-clinical-characteristics-and-outcome-of-cataract-extraction-with-intra-ocular-lens-implantation-in-a-kashmiri-population-a-hospital-based-study
#5
Wasim Rashid, Imtiyaz Lone, Adil Majid Mir, Aamir Rashid, Mehreen Latif
INTRODUCTION: Fuchs Heterochromic Iridocylitis (FHI) is a rare form of uveitis which is frequently complicated by cataract and glaucoma, but it does not show typical features of uveitis like pain, redness and posterior synechia. AIM: To study the clinical characteristics and outcome of cataract extraction with Intra Ocular Lens (IOL) implantation in patients with FHI. MATERIALS AND METHODS: The present prospective study was carried out in the Postgraduate Department of Ophthalmology, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Bemina from March 2012 to January 2015...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28200212/head-to-head-comparison-of-adaptive-statistical-and-model-based-iterative-reconstruction-algorithms-for-submillisievert-coronary-ct-angiography
#6
Dominik C Benz, Tobias A Fuchs, Christoph Gräni, Annina A Studer Bruengger, Olivier F Clerc, Fran Mikulicic, Michael Messerli, Julia Stehli, Mathias Possner, Aju P Pazhenkottil, Oliver Gaemperli, Philipp A Kaufmann, Ronny R Buechel
No abstract text is available yet for this article.
February 15, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28200085/how-does-social-support-affect-functional-impairment-in-late-life-findings-of-a-multicenter-prospective-cohort-study-in-germany
#7
André Hajek, Christian Brettschneider, Tina Mallon, Carolin van der Leeden, Silke Mamone, Birgitt Wiese, Siegfried Weyerer, Jochen Werle, Angela Fuchs, Michael Pentzek, Steffi G Riedel-Heller, Janine Stein, Horst Bickel, Dagmar Weeg, Kathrin Heser, Michael Wagner, Wolfgang Maier, Martin Scherer, Tobias Luck, Hans-Helmut König
No abstract text is available yet for this article.
February 14, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28200006/a-need-to-simplify-informed-consent-documents-in-cancer-clinical-trials-a-position-paper-of-the-arcad-group
#8
H Bleiberg, G Decoster, A de Gramont, P Rougier, A Sobrero, A Benson, B Chibaudel, J Y Douillard, C Eng, C Fuchs, M Fujii, R Labianca, A K Larsen, E Mitchell, H J Schmoll, D Sprumont, J Zalcberg
No abstract text is available yet for this article.
February 13, 2017: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28198867/acceleration-of-the-nonlinear-dynamics-in-p-doped-indium-phosphide-nanoscale-resonators
#9
Gregory Moille, Sylvain Combrié, Kerstin Fuchs, Matusala Yacob, Johann Peter Reithmaier, Alfredo de Rossi
We demonstrated a twofold acceleration of the fast time constant characterizing the recovery of a p-doped indium-phosphide photonic crystal all-optical gate. Time-resolved spectral analysis is compared to a three-dimensional drift-diffusion model for the carrier dynamics, demonstrating the transition from the ambipolar to the faster minority carrier dominated diffusion regime. This opens the perspective for faster yet efficient nanophotonic all-optical gates.
February 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28197292/chlorthalidone-plus-amiloride-reduces-the-central-systolic-blood-pressure-in-stage-1-hypertension-patients
#10
Leticia Aparecida Barufi Fernandes, Elizabeth do Espirito Santo Cestario, Luciana Neves Cosenso-Martin, Jose Fernando Vilela-Martin, Juan Carlos Yugar-Toledo, Flavio Danni Fuchs
BACKGROUND: Hypertension reduction strategies use blood pressure in the brachial artery as the primary endpoint. Individuals who achieve the target blood pressure reduction with antihypertensive treatment have residual cardiovascular risk attributed to the difference in pressure between the aorta and brachial artery. Antihypertensive treatment affects the intrinsic properties of the vascular wall and arterial stiffness markers and consequently the central pressure. Recent publications stress the importance of adequate control of the central compared to peripheral blood pressure...
December 2016: Cardiology Research
https://www.readbyqxmd.com/read/28196594/inactivation-of-interferon-receptor-promotes-the-establishment-of-immune-privileged-tumor-microenvironment
#11
Kanstantsin V Katlinski, Jun Gui, Yuliya V Katlinskaya, Angelíca Ortiz, Riddhita Chakraborty, Sabyasachi Bhattacharya, Christopher J Carbone, Daniel P Beiting, Melanie A Girondo, Amy R Peck, Ellen Puré, Priya Chatterji, Anil K Rustgi, J Alan Diehl, Constantinos Koumenis, Hallgeir Rui, Serge Y Fuchs
Refractoriness of solid tumors, including colorectal cancers (CRCs), to immunotherapies is attributed to the immunosuppressive tumor microenvironment that protects malignant cells from cytotoxic T lymphocytes (CTLs). We found that downregulation of the type I interferon receptor chain IFNAR1 occurs in human CRC and mouse models of CRC. Downregulation of IFNAR1 in tumor stroma stimulated CRC development and growth, played a key role in formation of the immune-privileged niche, and predicted poor prognosis in human CRC patients...
February 13, 2017: Cancer Cell
https://www.readbyqxmd.com/read/28191872/spatiotemporal-correlation-of-spinal-network-dynamics-underlying-spasms-in-chronic-spinalized-mice
#12
Carmelo Bellardita, Vittorio Caggiano, Roberto Leiras, Vanessa Caldeira, Andrea Fuchs, Julien Bouvier, Peter Löw, Ole Kiehn
Spasms after spinal cord injury (SCI) are debilitating involuntary muscle contractions that have been associated with increased motor neuron excitability and decreased inhibition. However, whether spasms involve activation of premotor spinal excitatory neuronal circuits is unknown. Here we use mouse genetics, electrophysiology, imaging and optogenetics to directly target major classes of spinal interneurons as well as motor neurons during spasms in a mouse model of chronic SCI. We find that assemblies of excitatory spinal interneurons are recruited by sensory input into functional circuits to generate persistent neural activity, which interacts with both the graded expression of plateau potentials in motor neurons to generate spasms, and inhibitory interneurons to curtail them...
February 13, 2017: ELife
https://www.readbyqxmd.com/read/28190942/cognitive-and-linguistic-predictors-of-mathematical-word-problems-with-and-without-irrelevant-information
#13
Amber Y Wang, Lynn S Fuchs, Douglas Fuchs
The purpose of this study was to identify cognitive and linguistic predictors of word problems with versus without irrelevant information. The sample was 701 2nd-grade students who received no specialized intervention on word problems. In the fall, they were assessed on initial arithmetic and word-problem skill as well as language ability, working memory capacity, and processing speed; in the spring, they were tested on a word-problem measure that included items with versus without irrelevant information. Significant predictors common to both forms of word problems were initial arithmetic and word problem-solving skill as well as language and working memory...
December 2016: Learning and Individual Differences
https://www.readbyqxmd.com/read/28188739/comparison-of-automated-devices-ux-2000-and-sedimax-autionmax-for-urine-samples-screening-a-multicenter-spanish-study
#14
Catalina Sánchez-Mora, Delia Acevedo, Maria Amelia Porres, Ana María Chaqués, Javier Zapardiel, Aurelia Gallego-Cabrera, Jose María López, Jose María Maesa
OBJECTIVES: In this study we aim to compare UX2000 (Sysmex Corp, Japan) and SediMAX/AutionMax (Arkray Factory Inc., Japan), totally automatized analyzers, against Fuchs-Rosenthal counting chamber, the gold standard technique for sediment analysis. DESIGN AND METHODS: Urine samples of 1454 patients from three Spanish hospitals were assessed for red and white blood cells (RBC; WBC) using three different techniques: flow cytometry, image-based method and Fuchs-Rosenthal counting chamber...
February 7, 2017: Clinical Biochemistry
https://www.readbyqxmd.com/read/28187700/long-term-body-mass-index-trends-after-living-donor-nephrectomy
#15
Christopher J Dru, Gerhard J Fuchs
OBJECTIVES: As the demand for kidney transplant allografts has increased, many centers are expanding the upper limit of acceptable body mass index for kidney donors. However, obesity is a risk factor for developing renal disease. Our goal was to quantify body mass index trends in donor nephrectomy patients and to institute nutrition counseling to promote sustainable weight loss to reduce the risk of metabolic syndrome-derived renal dysfunction. MATERIALS AND METHODS: Ninety patients who underwent donor nephrectomy between 2007 and 2012 consented to having height and weight data collected at multiple time points...
February 11, 2017: Experimental and Clinical Transplantation
https://www.readbyqxmd.com/read/28186738/substrate-mediated-c-c-and-c-h-coupling-after-dehalogenation
#16
Huihui Kong, Sha Yang, Hongying Gao, Alexander Timmer, Jonathan P Hill, Oscar Díaz Arado, Harry Mönig, Xinyan Huang, Qin Tang, Qingmin Ji, Wei Liu, Harald Fuchs
Intermolecular C-C coupling after cleavage of C-X (mostly, X = Br or I) bonds has been extensively studied for facilitating the synthesis of polymeric nanostructures. However, the accidental appearance of C-H coupling at the terminal carbon atoms would limit the successive extension of covalent polymers. To our knowledge, the selective C-H coupling after dehalogenation has not so far been reported, which may illuminate another interesting field of chemical synthesis on surfaces besides in-situ fabrication of polymers, i...
February 10, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28186617/sonographic-evaluation-of-surgical-repair-of-uterine-cesarean-scar-defects
#17
Michal Pomorski, Tomasz Fuchs, Anna Rosner-Tenerowicz, Mariusz Zimmer
BACKGROUND: The aim of the study was to assess the clinical outcomes of surgical repair of uterine cesarean scar defects with sonography (US). METHODS: Seven nonpregnant women with history of cesarean section and a large uterine scar defect were enrolled. The surgical repair was performed by minilaparotomy. The US assessment of the uterine scar was performed using a standardized approach at baseline, then at a first visit 2-3 days following the surgical intervention (V1) and at a follow-up visit 3 months later (V2)...
February 10, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28185741/clearance-of-tritrichomonas-foetus-in-experimentally-infected-heifers-protected-with-vaccines-based-on-killed-t-foetus-with-different-adjuvants
#18
Lumila I Fuchs, Marcelo C Fort, Dora Cano, Carina M Bonetti, Hugo D Giménez, Pablo M Vázquez, Diana Bacigalupe, Javier D Breccia, Carlos M Campero, Jorge A Oyhenart
Tritrichomonas foetus is a flagellated protozoan that causes a sexually transmitted disease in cattle. Trichomonosis is characterized by early abortions, subfertility and a significant decrease in productivity. Vaccine preparations containing whole T. foetus can reduce the time of residence of the pathogen in the host cervix after experimental infection. Here, T. foetus vaccines prepared with different adjuvants were tested, in parallel with a commercial vaccine, for their efficacy to clear the infection. The median time for clearance of infection was 69days in non-immunized animals, 55days in animals treated with aluminum hydroxide, 41days with oil-in-water or saponin based vaccines or with a commercial vaccine and 27days in animals treated with saponin plus aluminum hydroxide...
February 6, 2017: Vaccine
https://www.readbyqxmd.com/read/28183987/in-vivo-hypoxia-pet-imaging-quantifies-the-severity-of-arthritic-joint-inflammation-in-line-with-overexpression-of-hif-and-enhanced-ros-generation
#19
Kerstin Fuchs, Anna Kuehn, Moritz Mahling, Philipp Guenthoer, Andreas Hector, Dominik Hartl, Stefan Laufer, Ursula Kohlhofer, Leticia Quintanilla-Martinez, Gerald Reischl, Martin Röcken, Bernd J Pichler, Manfred Kneilling
Hypoxia is essential for the development of autoimmune diseases such as rheumatoid arthritis (RA) and is associated with the expression of reactive oxygen species (ROS), due to enhanced infiltration of immune cells. The aim of this study was to demonstrate the feasibility of measuring hypoxia non-invasively in vivo in arthritic ankles with positron emission tomography (PET)/magnetic resonance imaging (MRI) using the hypoxia tracers (18)F-fluoromisonidazole (FMISO) and (18)F-fluoroazomycinarabinoside (FAZA)...
February 9, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28177245/controlling-the-structure-of-supraballs-by-ph-responsive-particle-assembly
#20
Takafumi Sekido, Sanghyuk Wooh, Regina Fuchs, Michael Kappl, Yoshinobu Nakamura, Hans-Jürgen Butt, Syuji Fujii
Supraballs of various sizes and compositions can be fabricated via drying of drops of aqueous colloidal dispersions on super-liquid-repellent surfaces with no chemical waste and energy consumption. A "supraball" is a particle composed of colloids. Many properties, such as mechanical strength and porosity, are determined by the ordering of a colloidal assembly. To tune such properties, a colloidal assembly needs to be controlled when supraballs are formed during drying. Here, we introduce a method to control a colloidal assembly of supraballs by adjusting the dispersity of the colloids...
February 17, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
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