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deep transcranial magnetic stimulation

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https://www.readbyqxmd.com/read/29763711/efficacy-and-acceptability-of-non-invasive-brain-stimulation-for-the-treatment-of-adult-unipolar-and-bipolar-depression-a-systematic-review-and-meta-analysis-of-randomised-sham-controlled-trials
#1
REVIEW
Julian Mutz, Daniel R Edgcumbe, Andre R BrunoniMD, Cynthia H Y FuMD
We examined the efficacy and acceptability of non-invasive brain stimulation in adult unipolar and bipolar depression. Randomised sham-controlled trials of transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS) and theta-burst stimulation (TBS), without co-initiation of another treatment, were included. We analysed effects on response, remission, all-cause discontinuation rates and continuous depression severity measures. Fifty-six studies met our criteria for inclusion (N  = 3,058, mean age = 44...
May 12, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29659444/cerebellar-transcranial-magnetic-stimulation-facilitates-excitability-of-spinal-reflex-but-does-not-affect-cerebellar-inhibition-and-facilitation-in-spinocerebellar-ataxia
#2
Akiyoshi Matsugi, Yutaka Kikuchi, Kenta Kaneko, Yuta Seko, Masato Odagaki
Transcranial magnetic stimulation (TMS) over the cerebellum facilitates the spinal reflex in healthy humans. The aim of this study was to investigate whether such cerebellar spinal facilitation (CSpF) appears in patients with spinocerebellar ataxia (SCA) presenting with atrophy in the cerebellar gray matter and dentate nucleus. One patient with SCA type 6 and another with SCA type 31 participated in this study. TMS over the right primary motor cortex was used to induce motor-evoked potentials in the right first dorsal interosseous muscle, which were detected using electromyography...
April 13, 2018: Neuroreport
https://www.readbyqxmd.com/read/29606319/repetitive-movements-and-behaviors-in-neurological-and-psychiatric-practice-distinctions-and-similarities-between-tourette-disorder-and-obsessive-compulsive-disorder
#3
REVIEW
A Hartmann, B Millet
Repetitive movements are the hallmark of chronic tic disorders such as Tourette disorder (TD), whereas repetitive behaviors are characteristic of obsessive-compulsive disorder (OCD). Both disorders tend to frequently co-occur, as a substantial number of patients with TD also suffer from OCD and vice versa. While the clinical distinction between tics and OCD is usually easy, there are borderline forms, and correct symptom recognition is vital for choosing the appropriate treatment modalities for each disorder, be they pharmacological, psychotherapeutic (behavioral therapy) or brain stimulation (deep brain stimulation, repetitive transcranial magnetic stimulation)...
March 29, 2018: Revue Neurologique
https://www.readbyqxmd.com/read/29588984/effect-of-neurostimulation-on-cognition-and-mood-in-refractory-epilepsy
#4
REVIEW
Alvin Y Chan, John D Rolston, Vikram R Rao, Edward F Chang
Epilepsy is a common, debilitating neurological disorder characterized by recurrent seizures. Mood disorders and cognitive deficits are common comorbidities in epilepsy that, like seizures, profoundly influence quality of life and can be difficult to treat. For patients with refractory epilepsy who are not candidates for resection, neurostimulation, the electrical modulation of epileptogenic brain tissue, is an emerging treatment alternative. Several forms of neurostimulation are currently available, and therapy selection hinges on relative efficacy for seizure control and amelioration of neuropsychiatric comorbidities...
March 2018: Epilepsia Open
https://www.readbyqxmd.com/read/29543137/repeatability-and-reliability-of-muscle-relaxation-properties-induced-by-motor-cortical-stimulation
#5
Joery P Molenaar, Nicol C Voermans, Lysanne A de Jong, Dick F Stegeman, Jonne Doorduin, Baziel G van Engelen
Impaired muscle relaxation is a feature of many neuromuscular disorders. However, there are few tests available to quantify muscle relaxation. Transcranial magnetic stimulation (TMS) of the motor cortex can induce muscle relaxation by abruptly inhibiting corticospinal drive. The aim of our study is to investigate if repeatability and reliability of TMS-induced relaxation is greater than voluntary relaxation. Furthermore, effects of sex, cooling and fatigue on muscle relaxation properties were studied. Muscle relaxation of deep finger flexors was assessed in twenty-five healthy subjects (14 M and 11 F, aged 39...
March 15, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29524847/current-and-emerging-neuromodulation-therapies-for-addiction-insight-from-pre-clinical-studies
#6
REVIEW
Meaghan Creed
Neuromodulation therapies such as deep brain stimulation or transcranial magnetic stimulation have shown promise in reducing symptoms of addiction when applied to the prefontal cortex, nucleus accumbens or subthalamic nucleus. Pre-clinical investigations implicate modulation of the cortico-basal ganglia network in these therapeutic effects, and this mechanistic understanding is necessary to optimize stimulation paradigms. Recently, the principle that neuromodulation can reverse drug-evoked synaptic plasticity and reduce behavioral symptoms of addiction has inspired novel stimulation paradigms that have long-term effects in animal models...
March 7, 2018: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/29493559/neurostimulation-for-drug-resistant-epilepsy-a-systematic-review-of-clinical-evidence-for-efficacy-safety-contraindications-and-predictors-for-response
#7
Paul Boon, Elien De Cock, Ann Mertens, Eugen Trinka
PURPOSE OF REVIEW: Neurostimulation is becoming an increasingly accepted treatment alternative for patients with drug-resistant epilepsy (DRE) who are unsuitable surgery candidates. Standardized guidelines on when or how to use the various neurostimulation modalities are lacking. We conducted a systematic review on the currently available neurostimulation modalities primarily with regard to effectiveness and safety. RECENT FINDINGS: For vagus nerve stimulation (VNS), there is moderate-quality evidence for its effectiveness in adults with drug-resistant partial epilepsies...
April 2018: Current Opinion in Neurology
https://www.readbyqxmd.com/read/29463867/optogenetic-tractography-for-anatomo-functional-characterization-of-cortico-subcortical-neural-circuits-in-non-human-primates
#8
S Senova, C Poupon, J Dauguet, H J Stewart, G P Dugué, C Jan, K Hosomi, G S Ralph, L Barnes, X Drouot, C Pouzat, J F Mangin, F Pain, I Doignon, R Aron-Badin, E Brouillet, E S Boyden, K A Mitrophanous, P Hantraye, S Palfi
Dissecting neural circuitry in non-human primates (NHP) is crucial to identify potential neuromodulation anatomical targets for the treatment of pharmacoresistant neuropsychiatric diseases by electrical neuromodulation. How targets of deep brain stimulation (DBS) and cortical targets of transcranial magnetic stimulation (TMS) compare and might complement one another is an important question. Combining optogenetics and tractography may enable anatomo-functional characterization of large brain cortico-subcortical neural pathways...
February 20, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29457674/a-review-of-brain-stimulation-methods-to-treat-substance-use-disorders
#9
REVIEW
Alexandria S Coles, Karolina Kozak, Tony P George
BACKGROUND: Substance use disorders (SUDs) are a leading cause of disability worldwide. While several pharmacological and behavioral treatments for SUDs are available, these may not be effective for all patients. Recent studies using non-invasive neuromodulation techniques including Repetitive Transcranial Magnetic Stimulation (rTMS), Transcranial Direct Current Stimulation (tDCS), and Deep Brain Stimulation (DBS) have shown promise for SUD treatment. OBJECTIVE: Multiple studies were evaluated investigating the therapeutic potential of non-invasive brain stimulation techniques in treatment of SUDs...
March 2018: American Journal on Addictions
https://www.readbyqxmd.com/read/29454034/add-on-high-frequency-deep-transcranial-magnetic-stimulation-dtms-to-bilateral-prefrontal-cortex-in-depressive-episodes-of-patients-with-major-depressive-disorder-bipolar-disorder-i-and-major-depressive-with-alcohol-use-disorders
#10
Chiara Rapinesi, Georgios D Kotzalidis, Stefano Ferracuti, Nicoletta Girardi, Abraham Zangen, Gabriele Sani, Ruggero N Raccah, Paolo Girardi, Maurizio Pompili, Antonio Del Casale
BACKGROUND: Dorsolateral prefrontal cortex (DLPFC) is critically involved in mood and alcohol use disorders. OBJECTIVE: We aimed to investigate the safety of intervention with add-on bilateral prefrontal high-frequency deep transcranial magnetic stimulation (dTMS) and between-group differences in treatment response in patients with different types of depressive episodes, including major depressive episodes in the course of major depressive disorder (MDD), bipolar disorder, type I (BD-I), and MDD with alcohol use disorder (MDAUD)...
April 3, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29432784/cognitive-and-neuromodulation-strategies-for-unhealthy-eating-and-obesity-systematic-review-and-discussion-of-neurocognitive-mechanisms
#11
REVIEW
Laura Forcano, Fernanda Mata, Rafael de la Torre, Antonio Verdejo-Garcia
We systematically reviewed research on cognitive training and neuromodulation interventions for reducing food craving/intake, unhealthy diet and weight, and discussed their mechanisms of action. We reviewed 50 studies involving six cognitive trainings: Approach and Attentional Bias Modification, Implementation Intentions, Response Inhibition, Episodic Future Thinking and Working Memory; and four neuromodulation approaches: Transcranial Magnetic Stimulation (TMS), transcranial Direct Current Stimulation (tDCS), Deep Brain Stimulation (DBS) and Neurofeedback...
April 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29380485/neuromodulation-with-single-element-transcranial-focused-ultrasound-in-human-thalamus
#12
Wynn Legon, Leo Ai, Priya Bansal, Jerel K Mueller
Transcranial focused ultrasound (tFUS) has proven capable of stimulating cortical tissue in humans. tFUS confers high spatial resolutions with deep focal lengths and as such, has the potential to noninvasively modulate neural targets deep to the cortex in humans. We test the ability of single-element tFUS to noninvasively modulate unilateral thalamus in humans. Participants (N = 40) underwent either tFUS or sham neuromodulation targeted at the unilateral sensory thalamus that contains the ventro-posterior lateral (VPL) nucleus of thalamus...
May 2018: Human Brain Mapping
https://www.readbyqxmd.com/read/29373395/repetitive-deep-tms-for-parkinson-disease-a-3-month-double-blind-randomized-sham-controlled-study
#13
Oren S Cohen, Amihai Rigbi, Gilad Yahalom, Naama Warman-Alaluf, Zeev Nitsan, Abraham Zangen, Sharon Hassin-Baer
PURPOSE: To study the effects of a repetitive deep transcranial magnetic stimulation (rDTMS) in patients with Parkinson disease using the H5 coil for the low-frequency stimulation of the primary motor cortex, followed by the high-frequency rDTMS of the prefrontal cortex. METHODS: The main outcome measures were the total and motor scores of the Unified Parkinson's Disease Rating Scale (UPDRS). Secondary measures included rating of depression and quantitative motor tasks...
March 2018: Journal of Clinical Neurophysiology: Official Publication of the American Electroencephalographic Society
https://www.readbyqxmd.com/read/29369401/pallidal-deep-brain-stimulation-modulates-cortical-excitability-and-plasticity
#14
Zhen Ni, Sang Jin Kim, Nicolas Phielipp, Soumya Ghosh, Kaviraja Udupa, Carolyn A Gunraj, Utpal Saha, Mojgan Hodaie, Suneil K Kalia, Andres M Lozano, Darrin J Lee, Elena Moro, Alfonso Fasano, Mark Hallett, Anthony E Lang, Robert Chen
OBJECTIVE: Internal globus pallidus (GPi) deep brain stimulation (DBS) relieves symptoms in dystonia patients. However, the physiological effects produced by GPi DBS are not fully understood. In particular, how a single-pulse GPi DBS changes cortical circuits has never been investigated. We studied the modulation of motor cortical excitability and plasticity with single-pulse GPi DBS in dystonia patients with bilateral implantation of GPi DBS. METHODS: The cortical evoked potentials from DBS were recorded with electroencephalography...
February 2018: Annals of Neurology
https://www.readbyqxmd.com/read/29366375/patient-and-technician-oriented-attitudes-toward-transcranial-magnetic-stimulation-devices
#15
Brady Lonergan, Eliza Nguyen, Cara Lembo, Carrie Hinchman, Oscar G Morales, Daniel Z Press, Alvaro Pascual-Leone, Adam P Stern
Four transcranial magnetic stimulation (TMS) devices are currently approved for use in treatment-resistant depression. The authors present the first data-driven study examining the patient- and technician-experience using three of these distinct devices. A retrospective survey design with both patient and technician arms was utilized. The study population included patients who received TMS for treatment-resistant depression at the Berenson Allen Center for Noninvasive Brain Stimulation for the first time between 2013 and 2016 and technicians who worked in the program from 2009 to 2017...
January 25, 2018: Journal of Neuropsychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29326293/physiological-effects-of-subthalamic-nucleus-deep-brain-stimulation-surgery-in-cervical-dystonia
#16
Aparna Wagle Shukla, Jill L Ostrem, David E Vaillancourt, Robert Chen, Kelly D Foote, Michael S Okun
BACKGROUND: Subthalamic nucleus deep brain stimulation (STN DBS) surgery is clinically effective for treatment of cervical dystonia; however, the underlying physiology has not been examined. We used transcranial magnetic stimulation (TMS) to examine the effects of STN DBS on sensorimotor integration, sensorimotor plasticity and motor cortex excitability, which are identified as the key pathophysiological features underlying dystonia. METHODS: TMS paradigms of short latency afferent inhibition (SAI) and long latency afferent inhibition (LAI) were used to examine the sensorimotor integration...
January 11, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29259998/safety-and-preliminary-efficacy-of-deep-transcranial-magnetic-stimulation-in-ms-related-fatigue
#17
Gunnar Gaede, Marina Tiede, Ina Lorenz, Alexander U Brandt, Caspar Pfueller, Jan Dörr, Judith Bellmann-Strobl, Sophie K Piper, Yiftach Roth, Abraham Zangen, Sven Schippling, Friedemann Paul
Objective: To conduct a randomized, sham-controlled phase I/IIa study to evaluate the safety and preliminary efficacy of deep brain H-coil repetitive transcranial magnetic stimulation (rTMS) over the prefrontal cortex (PFC) and the primary motor cortex (MC) in patients with MS with fatigue or depression (NCT01106365). Methods: Thirty-three patients with MS were recruited to undergo 18 consecutive rTMS sessions over 6 weeks, followed by follow-up (FU) assessments over 6 weeks...
January 2018: Neurology® Neuroimmunology & Neuroinflammation
https://www.readbyqxmd.com/read/29219631/tourette-syndrome-and-other-chronic-tic-disorders-an-update-on-clinical-management
#18
Davide Martino, Tamara M Pringsheim
The management of Tourette syndrome (TS) and other chronic tic disorders occurs in multiple stages and begins with comprehensive assessment and complex psychoeducation. Behavioral and pharmacological interventions (second stage) are needed when tics cause physical or psychosocial impairment. Deep brain stimulation surgery or experimental therapies represent the third stage. Areas covered: Discussed are recent advances in assessment and therapy of chronic tic disorders, encompassing the three stages of intervention, with the addition of experimental, non-invasive brain stimulation strategies...
February 2018: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29191439/effects-of-cerebellar-neuromodulation-in-movement-disorders-a-systematic-review
#19
REVIEW
Carina França, Daniel Ciampi de Andrade, Manoel Jacobsen Teixeira, Ricardo Galhardoni, Valquiria Silva, Egberto Reis Barbosa, Rubens Gisbert Cury
BACKGROUND: The cerebellum is involved in the pathophysiology of many movement disorders and its importance in the field of neuromodulation is growing. OBJECTIVES: To review the current evidence for cerebellar modulation in movement disorders and its safety profile. METHODS: Eligible studies were identified after a systematic literature review of the effects of cerebellar modulation in cerebellar ataxia, Parkinson's disease (PD), essential tremor (ET), dystonia and progressive supranuclear palsy (PSP)...
March 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29178240/post-operative-localization-of-deep-brain-stimulation-electrodes-in-the-subthalamus-using-transcranial-sonography
#20
Lourdes Ispierto, Jorge Muñoz, Josep Maria Cladellas, Patricia Cuadras, Jaume Capellades, Pilar Latorre, Antoni Dávalos, Tim Vancamp, Ramiro Álvarez
OBJECTIVES: The correct positioning of deep brain stimulation electrodes determines the success of surgery. In this study, we attempt to validate transcranial sonography (TCS) as a method for early postoperative confirmation of electrode location in the subthalamic nucleus (STN). MATERIALS AND METHODS: Nineteen patients diagnosed with Parkinson's disease were enrolled in the study. Postoperative TCS was applied to measure the distance between the implanted electrodes and the third ventricle in the axial plane...
November 27, 2017: Neuromodulation: Journal of the International Neuromodulation Society
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