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https://www.readbyqxmd.com/read/28650753/lower-extremity-infections-caused-by-serratia-marcescens-a-report-of-three-cases-and-a-literature-review
#1
Luis Marin, Raymond Rowan, Ana Mantilla, Bamidele Olupona, Ann MacIntyre
Serratia marcescens is a ubiquitous, facultatively anaerobic, gram-negative bacillus that has been cited to cause infection in immunocompromised populations. In the literature, S marcescens infections of the lower extremity have presented as granulomatous ulceration, abscess, bullous cellulitis, and necrotizing fasciitis. Herein we present a series of three cases of lower-extremity infections in which S marcescens was the sole or a contributing pathogen. We discuss the commonalities of these three cases as well as with those previously cited...
May 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28646667/prevalence-and-characterization-of-extended-spectrum-%C3%AE-lactamase-esbl-and-ampc-%C3%AE-lactamase-producing-enterobacteriaceae-in-fresh-pork-meat-at-processing-level-in-germany
#2
Franziska Schill, Amir Abdulmawjood, Günter Klein, Felix Reich
ESBL or AmpC β-lactamase producing Enterobacteriaceae is an increasing concern in human medicine. A distribution via the food chain is discussed, but less is known about these bacteria on fresh pork meat. The aim of this study was to investigate the prevalence of ESBL/AmpC Enterobacteriaceae bacteria in fresh pork meat at processing level in Germany. The analysis comprised microbiological hygiene parameters and further pheno- and genotypical characterization of ESBL/AmpC isolates. The examination included three pools of meat and one corresponding meat juice sample from each of the tested pork meat batches (n=63)...
June 15, 2017: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/28641915/the-antimicrobial-spectrum-of-xeroform-%C3%A2
#3
David J Barillo, Anthony R Barillo, Sarah Korn, Kan Lam, Paul S Attar
INTRODUCTION/BACKGROUND: Xeroform(®) is a petrolatum-based fine mesh gauze containing 3% bismuth tribromophenate. Bismuth, similar to other metals, has antimicrobial properties. Xeroform(®) has been used for decades in burn and plastic surgery as a donor site dressing and as a covering for wounds or partial thickness burns. Despite this, the antimicrobial spectrum of Xeroform(®) remains largely unknown. We examined the in-vitro efficacy of Xeroform(®) against common burn pathogens using zone-of-inhibition methodology in a commercial research facility...
June 19, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28640920/pathogen-specific-mortality-in-very-low-birth-weight-infants-with-primary-bloodstream-infection
#4
Brar C Piening, Christine Geffers, Petra Gastmeier, Frank Schwab
OBJECTIVE: Mortality in very low birth weight infants following microbiology confirmed primary bloodstream infections varies with the type of causative pathogen. Given evidence from other studies that infections with gram negative bacteria and fungi cause a higher case fatality risk. We tried to confirm this in a nation-wide multi-center trial. METHODS: A cohort of 55,465 very low birth weight infants from 242 neonatal departments participating in the German national neonatal infection surveillance system NEO-KISS was used to investigate differences in the case fatality risk of microbiology confirmed primary bloodstream infections according to individual pathogens...
2017: PloS One
https://www.readbyqxmd.com/read/28636609/genomic-and-phenotypic-characterisation-of-fluoroquinolone-resistance-mechanisms-in-enterobacteriaceae-in-durban-south-africa
#5
John Osei Sekyere, Daniel Gyamfi Amoako
Resistance to fluoroquinolones (FQ) is being increasingly reported and found to be mediated by efflux pumps, plasmid-mediated quinolone resistance genes (PMQR) and mutations in gyrA, gyrB, parC and parE. However, studies reporting on FQ resistance mechanisms (FQRM), particularly in Africa, are focused mostly on Salmonella. This study used a whole-genome-based approach to describe FQRM in forty-eight clinical Enterobacteriaceae isolates comprising of Klebsiella pneumoniae (n = 21), Serratia marcescens (n = 12), Enterobacter spp...
2017: PloS One
https://www.readbyqxmd.com/read/28626312/bacterial-contamination-in-physical-therapy-departments-in-the-state-of-kuwait
#6
Sameera H Aljadi, Mashael Al-Shemmari, Jumana Al-Ramzi, Shoug Al-Abdullatif, Zahraa Hajeyah, Laila Jamal, Sara Al-Bahar
[Purpose] Interferential therapy and electrical stimulation are electrophysical modalities commonly used in physical therapy departments to treat patients with musculoskeletal problems. These machines are applied directly to the patient's skin via a medium or electrodes, which can facilitate the transmission of microorganisms from one patient to another. The purpose of this study was to determine the extent of microorganism contamination in the machines sponges at physical therapy departments in Kuwait hospitals...
June 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28624621/innate-immune-system-capabilities-of-the-asian-citrus-psyllid-diaphorina-citri
#7
Alex P Arp, Xavier Martini, Kirsten S Pelz-Stelinski
Citrus production worldwide is currently threatened by Huanglongbing, or citrus greening disease. The associated pathogen, Candidatus Liberibacter asiaticus (CLas), is transmitted by the Asian citrus psyllid, Diaphorina citri. Annotation of the D. citri genome revealed a reduced innate immune system lacking a number of antimicrobial peptides and the Imd pathway associated with defense against Gram-negative bacteria. We characterized this apparent immune reduction in survival assays in which D. citri were exposed to Gram-negative or Gram-positive bacteria...
June 15, 2017: Journal of Invertebrate Pathology
https://www.readbyqxmd.com/read/28620370/environmental-t4-family-bacteriophages-evolve-to-escape-abortive-infection-via-multiple-routes-in-a-bacterial-host-employing-altruistic-suicide-through-type-iii-toxin-antitoxin-systems
#8
Bihe Chen, Chidiebere Akusobi, Xinzhe Fang, George P C Salmond
Abortive infection is an anti-phage mechanism employed by a bacterium to initiate its own death upon phage infection. This reduces, or eliminates, production of viral progeny and protects clonal siblings in the bacterial population by an act akin to an "altruistic suicide." Abortive infection can be mediated by a Type III toxin-antitoxin system called ToxINPa consisting of an endoribonuclease toxin and RNA antitoxin. ToxINPa is a heterohexameric quaternary complex in which pseudoknotted RNA inhibits the toxicity of the toxin until infection by certain phages causes destabilization of ToxINPa, leading to bacteriostasis and, eventually, lethality...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28612090/organic-solvent-tolerant-marine-microorganisms-as-catalysts-for-kinetic-resolution-of-cyclic-%C3%AE-hydroxy-ketones
#9
Bi -Shuang Chen, Hui Liu, Fayene Zeferino Ribeiro de Souza, Lan Liu
Chiral cyclic β-hydroxy ketones represent key motifs in the production of natural products of biological interest. Although the molecules are structurally simple, they require cumbersome synthetic steps to get access to them and their synthesis remains a challenge in organic chemistry. In this report, we describe a straightforward approach to enantiomerically enriched (R)- and (S)-3-hydroxycyclopentanone 2a, (R)- and (S)-3-hydroxycyclohexanone 2b, and (R)- and (S)-3-hydroxycycloheptanone 2c involving a transesterification resolution of the racemates using whole cells of marine microorganisms as catalysts and vinyl acetate the acyl donor and solvent...
June 13, 2017: Marine Biotechnology
https://www.readbyqxmd.com/read/28609134/relationships-among-microbial-communities-maternal-cells-oligosaccharides-and-macronutrients-in-human-milk
#10
Janet E Williams, William J Price, Bahman Shafii, Katherine M Yahvah, Lars Bode, Mark A McGuire, Michelle K McGuire
BACKGROUND: Human milk provides all essential nutrients necessary for early life and is rich in nonnutrients, maternally derived (host) cells, and bacteria, but almost nothing is known about the interplay among these components. Research aim: The primary objective of this research was to characterize relationships among macronutrients, maternal cells, and bacteria in milk. METHODS: Milk samples were collected from 16 women and analyzed for protein, lipid, fatty acid, lactose, and human milk oligosaccharide concentrations...
June 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28596408/draft-genome-sequence-of-serratia-proteamaculans-mfpa44a14-05-a-model-organism-for-the-study-of-meat-and-seafood-spoilage
#11
Lysiane Fougy, Gwendoline Coeuret, Marie-Christine Champomier-Vergès, Stéphane Chaillou
In this study, we present a draft genome sequence of Serratia proteamaculans MFPA44A14-05. This strain was isolated from a spoiled organic modified-atmosphere-packed beef carpaccio. The draft genome sequence will contribute to the understanding of the role of the S. proteamaculans species in meat and seafood spoilage.
June 8, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28596386/genome-sequence-of-serratia-marcescens-phage-bf
#12
Eoghan Casey, Brian Fitzgerald, Jennifer Mahony, Gabriele Andrea Lugli, Marco Ventura, Douwe van Sinderen
Phages infecting Serratia marcescens, a common causative agent of nosocomial infections, have potential therapeutic applications. Here, we report the complete genome of the novel S. marcescens phage BF, representing the third-largest phage genome sequenced to date.
June 8, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28591237/association-between-pathogens-from-tracheal-aspirate-and-oral-biofilm-of-patients-on-mechanical-ventilation
#13
Luana Carneiro Diniz Souza, Vanise Barros Rodrigues da Mota, Alícia Valéria Dos Santos Zaranza de Carvalho, Rita da Graça Carvalhal Frazão Corrêa, Silvana Amado Libério, Fernanda Ferreira Lopes
The aim of this study was to detect possible associations between respiratory pathogens from tracheal aspirate and oral biofilm samples in intubated patients in an intensive care unit (ICU), and to identify the most common respiratory pathogens in oral biofilm, particularly in patients that developed ventilator-associated pneumonia (VAP). Two oral biofilm samples were collected from the tongue of intubated patients (at admission and after 48 hours) and analyzed by culture with the Antibiotic Sensitivity Test...
June 5, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28586429/hafnia-an-enterobacterial-genus-naturally-resistant-to-colistin-revealed-by-three-susceptibility-testing-methods
#14
Aurélie Jayol, Marion Saly, Patrice Nordmann, Armelle Ménard, Laurent Poirel, Véronique Dubois
Objectives: To determine the susceptibility to colistin of Hafnia alvei and Hafnia paralvei , and to compare methods for colistin resistance detection in the Hafnia genus. Methods: A collection of 25 Hafnia isolates was studied. Species were identified by using 16S rRNA gene sequencing with subsequent phylogeny analysis. Susceptibility to colistin was determined using the broth microdilution (BMD) reference method, the Phoenix automated system, the Rapid Polymyxin NP test, the Etest system and the disc diffusion method...
June 6, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28584393/adult-bacterial-exposure-increases-behavioral-variation-and-drives-higher-repeatability-in-field-crickets
#15
Nicholas DiRienzo, Petri T Niemelä, Ann V Hedrick, Raine Kortet
Among-individual differences in behavior are now a widely studied research-focus within the field of behavioral ecology. Furthermore, elements of an animal's internal state, such as energy or fat reserves, and infection status can have large impacts on behaviors. Despite this, we still know little regarding how state may affect behavioral variation. Recent exposure to pathogens may have a particularly large impact on behavioral expression given that it likely activates costly immune pathways, potentially forcing organism to make behavioral tradeoffs...
November 2016: Behavioral Ecology and Sociobiology
https://www.readbyqxmd.com/read/28578959/enzymatic-production-of-n-acetyl-d-glucosamine-from-crayfish-shell-wastes-pretreated-via-high-pressure-homogenization
#16
Guoguang Wei, Alei Zhang, Kequan Chen, Pingkai Ouyang
This study presents an efficient pretreatment of crayfish shell using high pressure homogenization that enables N-acetyl-d-glucosamine (GlcNAc) production by chitinase. Firstly, the chitinase from Serratia proteamaculans NJ303 was screened for its ability to degrade crayfish shell and produce GlcNAc as the sole product. Secondly, high pressure homogenization, which caused the crayfish shell to adopt a fluffy netted structure that was characterized by Scanning electron microscope (SEM), Fourier transform infrared spectrometer (FT-IR), X-ray diffraction (XRD), was evaluated as the best pretreatment method...
September 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28578396/neonicotinoid-induced-pathogen-susceptibility-is-mitigated-by-lactobacillus-plantarum-immune-stimulation-in-a-drosophila-melanogaster-model
#17
Brendan A Daisley, Mark Trinder, Tim W McDowell, Hylke Welle, Josh S Dube, Sohrab N Ali, Hon S Leong, Mark W Sumarah, Gregor Reid
Pesticides are used extensively in food production to maximize crop yields. However, neonicotinoid insecticides exert unintentional toxicity to honey bees (Apis mellifera) that may partially be associated with massive population declines referred to as colony collapse disorder. We hypothesized that imidacloprid (common neonicotinoid; IMI) exposure would make Drosophila melanogaster (an insect model for the honey bee) more susceptible to bacterial pathogens, heat stress, and intestinal dysbiosis. Our results suggested that the immune deficiency (Imd) pathway is necessary for D...
June 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28577521/seven-chronic-granulomatous-disease-cases-in-a-single-center-experience-and-a-review-of-the-literature
#18
Şeyhan Kutluğ, Gülnar Şensoy, Asuman Birinci, Berkay Saraymen, Mustafa Yavuz Köker, Alişan YΙldΙran
BACKGROUND: Chronic granulomatous disease (CGD) is a rare primary immunodeficiency caused by defects in the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase enzyme system. This disease causes the disordered functioning of phagocytic cells. It is characterized by life-threatening and/or recurrent infections by bacteria and fungi. CGD has one X-linked recessive subtype (X-CGD) and four autosomal recessive subtypes (AR-CGD), and the differential diagnosis is important in such chronic inflammatory disorders...
June 1, 2017: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/28576365/influence-of-soy-fortification-on-microbial-diversity-during-cassava-fermentation-and-subsequent-physicochemical-characteristics-of-garri
#19
Ndidiamaka Nnenaya Ahaotu, Amarachukwu Anyogu, Promiselynda Obioha, Lawrence Aririatu, Vincent Ifeanyi Ibekwe, Solomon Oranusi, Jane P Sutherland, Labia Irene Ivette Ouoba
This study investigated the influence of the addition of soy products on the microbiology, nutritional and physico-chemical characteristics of garri, a fermented cassava product. Malted soy flour (MSF) and soy protein (SP) were separately added (12% w/w) to cassava mash prior to controlled fermentation, while non-supplemented cassava mash served as a control. Identification of lactic acid bacteria (LAB) and aerobic mesophilic bacteria was accomplished by repetitive sequence based (rep)-PCR analysis and 16S rRNA gene sequencing...
September 2017: Food Microbiology
https://www.readbyqxmd.com/read/28571897/-implication-of-a-national-outbreak-of-serratia-marcescens-associated-with-a-contaminated-solution-of-chlorhexidine-in-a-paediatric-hospital
#20
Áurea Morillo, María José Torres, María Teresa Alonso Salas, Manuel Conde, Javier Aznar
No abstract text is available yet for this article.
May 29, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
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