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https://www.readbyqxmd.com/read/29774863/ehrlichia-muris-in-ixodes-cookei-ticks-northeastern-united-states-2016-2017
#1
Guang Xu, Patrick Pearson, Stephen M Rich
Ehrlichia muris is an agent of human ehrlichiosis. To determine its geographic spread in the United States, during 2016-2017, we tested 8,760 ticks from 45 states. A distinct clade of E. muris found in 3 Ixodes cookei ticks from the northeastern United States suggests transmission by these ticks in this region.
June 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29774138/clinical-evaluation-of-morgellons-disease-in-a-cohort-of-north-american-patients
#2
Melissa C Fesler, Marianne J Middelveen, Raphael B Stricker
Morgellons disease (MD) is a dermatological condition characterized by aberrant production of keratin and collagen fibers in skin. Although infection with Borrelia burgdorferi , the causative agent of Lyme disease (LD), has been associated with MD, relatively few studies have hitherto provided epidemiological evidence regarding this association. A cohort of 1000 seropositive North American LD patients was evaluated for the presence of MD. Patients were diagnosed with MD based on detection of microscopic fibers in skin lesions or under unbroken skin...
April 23, 2018: Dermatology Reports
https://www.readbyqxmd.com/read/29704268/characteristics-of-hemostasis-during-experimental-ehrlichia-canis-infection
#3
Sarah Shropshire, Christine Olver, Michael Lappin
BACKGROUND: Ehrlichia canis infection in dogs can cause thrombocytopenia and clinical evidence of bleeding. It is unknown why some dogs show signs of bleeding whereas others do not despite clinically relevant thrombocytopenia. HYPOTHESIS/OBJECTIVES: Activated platelets, decreased fibrinolysis or both mitigate bleeding tendency. Assess standard hemostatic variables, platelet dynamics, and specialized coagulation testing in dogs experimentally infected with E. canis to evaluate this clinical discrepancy...
April 27, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29696073/a-cross-sectional-study-of-small-mammals-for-tick-borne-pathogen-infection-in-northern-mongolia
#4
Laura A Pulscher, Thomas C Moore, Luke Caddell, Lkhagvatseren Sukhbaatar, Michael E von Fricken, Benjamin D Anderson, Battsetseg Gonchigoo, Gregory C Gray
Background : Tick-borne pathogens (TBPs) are frequently studied in developed nations but are often neglected in emerging countries. In Mongolia, TBP research is especially sparse, with few research reports focusing upon human and domestic animal disease and tick ecology. However, little information exists on TBPs in small mammals. Methods : In this 2016 cross-sectional pilot study, we sought to uniquely study wildlife for TBPs. We live-trapped small mammals, and tested their whole blood, serum and ear biopsy samples for molecular or serological evidence of Borrelia spp...
2018: Infection Ecology & Epidemiology
https://www.readbyqxmd.com/read/29670161/impact-of-three-different-mutations-in-ehrlichia-chaffeensis-in-altering-the-global-gene-expression-patterns
#5
Chandramouli Kondethimmanahalli, Roman Ganta
The rickettsial pathogen Ehrlichia chaffeensis causes a tick-borne disease, human monocytic ehrlichiosis. Mutations within certain genomic locations of the pathogen aid in understanding the pathogenesis and in developing attenuated vaccines. Our previous studies demonstrated that mutations in different genomic sites in E. chaffeensis caused variable impacts on their growth and attenuation in vertebrate and tick hosts. Here, we assessed the effect of three mutations on transcriptional changes using RNA deep-sequencing technology...
April 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29668040/graft-loss-attributed-to-possible-transfusion-transmitted-ehrlichiosis-following-cord-blood-stem-cell-transplant
#6
A Mah, G M Viola, E Ariza Heredia, K Rezvani, P Kebriaei, M M Bhatti, X Han, E J Shpall, V Mulanovich
We present a case of possible transfusion-transmitted Ehrlichia chaffeensis infection in a heavily transfused cord blood transplant recipient, resulting in severe infection and graft loss. Transfusion-transmitted, vector-borne infections in immunocompromised individuals can have severe consequences, and should be considered in hospitalized patients receiving blood products with unexplained fever or sepsis. This article is protected by copyright. All rights reserved.
April 18, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29657007/update-on-flea-and-tick-associated-diseases-of-cats
#7
Michael R Lappin
There are multiple vector-borne diseases in cats, the most prominent being those transmitted by mosquitos, sand flies, fleas, and ticks. Many of the agents vectored by fleas or ticks have been grown or amplified from blood or have induced antibodies in the serum of normal cats or those with clinical signs like fever and will be the focus of this manuscript. As high as 80% of fleas collected from cats contain at least one organism that could induce illness in cats or people. Anaplasma phagocytophilum, Bartonella spp...
April 30, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29649265/bacterial-and-protozoal-pathogens-found-in-ticks-collected-from-humans-in-corum-province-of-turkey
#8
Djursun Karasartova, Ayse Semra Gureser, Tuncay Gokce, Bekir Celebi, Derya Yapar, Adem Keskin, Selim Celik, Yasemin Ece, Ali Kemal Erenler, Selma Usluca, Kosta Y Mumcuoglu, Aysegul Taylan-Ozkan
BACKGROUND: Tick-borne diseases are increasing all over the word, including Turkey. The aim of this study was to determine the bacterial and protozoan vector-borne pathogens in ticks infesting humans in the Corum province of Turkey. METHODOLOGY/PRINCIPAL FINDINGS: From March to November 2014 a total of 322 ticks were collected from patients who attended the local hospitals with tick bites. Ticks were screened by real time-PCR and PCR, and obtained amplicons were sequenced...
April 12, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29643078/-ehrlichia-chaffeensis-trp75-interacts-with-host-cell-targets-involved-in-homeostasis-cytoskeleton-organization-and-apoptosis-regulation-to-promote-infection
#9
Tian Luo, Shubhajit Mitra, Jere W McBride
Ehrlichia chaffeensis is an obligately intracellular bacterium that exhibits tropism for mononuclear phagocytes. The mechanisms involved in E. chaffeensis infection of the host cell and evasion of host defenses are not fully defined, but a subset of type 1 secreted tandem repeat protein (TRP) effectors play important roles. Recently, we determined molecular interactions of TRP120, TRP47, and TRP32 with the eukaryotic host cell. In this investigation, we used yeast two-hybrid analysis to reveal that another E...
April 25, 2018: MSphere
https://www.readbyqxmd.com/read/29622515/tick-borne-haemoparasites-and-anaplasmataceae-in-domestic-dogs-in-zambia
#10
Yongjin Qiu, Chiho Kaneko, Masahiro Kajihara, Saasa Ngonda, Edgar Simulundu, Walter Muleya, May June Thu, Mudenda Bernard Hang'ombe, Ken Katakura, Ayato Takada, Hirofumi Sawa, Martin Simuunza, Ryo Nakao
Tick-borne diseases (TBDs), including emerging and re-emerging infectious diseases, are important threats to human and animal health worldwide. Indeed, the number of reported human and animal infectious cases of novel TBD agents has increased in recent decades. However, TBDs tend to be neglected, especially in resource-limited countries that often have limited diagnostic capacity. The aim of this molecular survey was to detect and characterise tick-borne pathogens (Babesia, Theileria, and Hepatozoon parasites and Anaplasmataceae bacteria) in domestic dogs in Zambia...
March 26, 2018: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/29584589/molecular-characterization-and-phylogenetic-analysis-of-anaplasma-spp-and-ehrlichia-spp-isolated-from-various-ticks-in-southeastern-and-northwestern-regions-of-iran
#11
Ahmad Jafar Bekloo, Maryam Roya Ramzgouyan, Sadegh Shirian, Faezeh Faghihi, Hassan Bakhshi, Fatemeh Naseri, Mehdi Sedaghat, Zakkyeh Telmadarraiy
INTRODUCTION: Anaplasma/Ehrlichia species are tick-transmitted pathogens that cause infections in humans and numerous domestic and wild animal species. There is no information available on the molecular characteristics and phylogenetic position of Anaplasma/Ehrlichia spp. isolated from tick species from different geographic locations in Iran. The aim of this study was to determine the prevalence, molecular characteristics, and phylogenetic relationship of both Anaplasma spp. and Ehrlichia spp...
March 20, 2018: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29580089/detection-and-molecular-characterisation-of-ehrlichia-canis-in-naturally-infected-dogs-in-south-west-nigeria
#12
Olukayode Olugbenga Daramola, Michael Irewole Takeet, Ibironke Kofoworola Oyewusi, Mufutau Atanda Oyekunle, Adewale Oladele Talabi
Canine ehrlichiosis is an important tick-borne rickettsial disease mainly caused by Ehrlichia canis. This study aimed to detect and characterise E. canis in dogs in Abeokuta, Nigeria by microscopy and nested PCR. Blood samples were collected from 205 dogs, thin smears were made, field-stained, and DNA was extracted from the blood samples. A partial region of the 16S rRNA gene was amplified by polymerase chain reaction (PCR) and sequenced unidirectionally. Ehrlichial morulae were detected in three dogs (1.5%)...
March 2018: Acta Veterinaria Hungarica
https://www.readbyqxmd.com/read/29554969/infection-by-mycoplasma-spp-feline-immunodeficiency-virus-and-feline-leukemia-virus-in-cats-from-an-area-endemic-for-visceral-leishmaniasis
#13
Mary Marcondes, Karina Y Hirata, Juliana P Vides, Ludmila S V Sobrinho, Jaqueline S Azevedo, Thállitha S W J Vieira, Rafael F C Vieira
BACKGROUND: Visceral leishmaniasis (VL) has been increasingly recognized in cats living in areas endemic for the disease. Co-infection with Leishmania infantum and other infectious agents is well established in dogs. However, for cats, data on co-infections with L. infantum and other infectious agents are still sparse. The aim of this study was to identify the prevalence of vector-borne pathogens, Mycoplasma spp., feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) in cats from an area endemic for VL in southeastern Brazil...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29554954/ehrlichia-spp-infection-in-rural-dogs-from-remote-indigenous-villages-in-north-eastern-brazil
#14
Filipe Dantas-Torres, Yury Yzabella da Silva, Débora Elienai de Oliveira Miranda, Kamila Gaudêncio da Silva Sales, Luciana Aguiar Figueredo, Domenico Otranto
BACKGROUND: Ehrlichia canis is a tick-borne bacterium that causes severe, life-threatening disease in dogs, being more prevalent in tropical and subtropical countries. Randomized studies conducted in Brazil indicate that the prevalence of E. canis infection in dogs ranges from 0.7% to over 50.0%. In a study conducted in northern Brazil, the prevalence was higher in dogs from urban areas, as compared to dogs from rural areas. In the present study, we investigated the exposure to Ehrlichia spp...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29554947/molecular-survey-of-neglected-bacterial-pathogens-reveals-an-abundant-diversity-of-species-and-genotypes-in-ticks-collected-from-animal-hosts-across-romania
#15
Martin O Andersson, Conny Tolf, Paula Tamba, Mircea Stefanache, Gabriel Radbea, Dimitrios Frangoulidis, Herbert Tomaso, Jonas Waldenström, Gerhard Dobler, Lidia Chitimia-Dobler
BACKGROUND: Ticks are transmitting a wide range of bacterial pathogens that cause substantial morbidity and mortality in domestic animals. The full pathogen burden transmitted by tick vectors is incompletely studied in many geographical areas, and extensive studies are required to fully understand the diversity and distribution of pathogens transmitted by ticks. RESULTS: We sampled 824 ticks of 11 species collected in 19 counties in Romania. Ticks were collected mainly from dogs, but also from other domestic and wild animals, and were subjected to molecular screening for pathogens...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29554946/molecular-detection-of-anaplasma-bovis-ehrlichia-canis-and-hepatozoon-felis-in-cats-from-luanda-angola
#16
Ana Cristina Oliveira, Maria Francisca Luz, Sara Granada, Hugo Vilhena, Yaarit Nachum-Biala, Ana Patrícia Lopes, Luís Cardoso, Gad Baneth
BACKGROUND: Molecular identification of tick-borne pathogen infection in cats from Africa is scarce. The presence of bacterial (Anaplasma and Ehrlichia) and protozoal (Babesia and Hepatozoon) agents was investigated in blood samples from 102 domestic cats from Luanda, Angola, by polymerase chain reaction and DNA sequencing. RESULTS: Three cats (2.9%) were found infected with Ehrlichia canis, three (2.9%) with Hepatozoon felis and one (1.0%) with Anaplasma bovis...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29554933/occurrence-of-hepatozoon-canis-adeleorina-hepatozoidae-and-anaplasma-spp-rickettsiales-anaplasmataceae-in-black-backed-jackals-canis-mesomelas-in-south-africa
#17
Barend L Penzhorn, Edward C Netherlands, Courtney A Cook, Nico J Smit, Ilse Vorster, Robert F Harrison-White, Marinda C Oosthuizen
BACKGROUND: Domestic dogs are not native to sub-Saharan Africa, which may account for their susceptibility to Babesia rossi, of which endemic black-backed jackals (Canis mesomelas) are natural reservoirs. There is virtually no information on the occurrence of potentially pathogenic haemogregarines (e.g. Hepatozoon canis) or even rickettsial bacteria (e.g. Ehrlichia spp. and Anaplasma spp.) in indigenous canids in sub-Saharan Africa. Such organisms could pose a risk to domestic dogs, as well as to populations of endangered indigenous canid species...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29554932/association-between-canine-leishmaniosis-and-ehrlichia-canis-co-infection-a-prospective-case-control-study
#18
Charalampos Attipa, Laia Solano-Gallego, Kostas Papasouliotis, Francesca Soutter, David Morris, Chris Helps, Scott Carver, Séverine Tasker
BACKGROUND: In the Mediterranean basin, Leishmania infantum is a major cause of disease in dogs, which are frequently co-infected with other vector-borne pathogens (VBP). However, the associations between dogs with clinical leishmaniosis (ClinL) and VBP co-infections have not been studied. We assessed the risk of VBP infections in dogs with ClinL and healthy controls. METHODS: We conducted a prospective case-control study of dogs with ClinL (positive qPCR and ELISA antibody for L...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29554931/clinical-evaluation-of-outdoor-cats-exposed-to-ectoparasites-and-associated-risk-for-vector-borne-infections-in-southern-italy
#19
Maria Flaminia Persichetti, Maria Grazia Pennisi, Angela Vullo, Marisa Masucci, Antonella Migliazzo, Laia Solano-Gallego
BACKGROUND: Cats can be carriers of infected arthropods and be infected with several vector-borne pathogens (VBP) but there is limited knowledge about their pathogenic role in cats. RESULTS: A cross-sectional controlled study investigated the clinical status and antibody (Bartonella henselae, Rickettsia conorii, Ehrlichia canis, Anaplasma phagocytophilum, Babesia microti and Leishmania infantum) and/or blood PCR (Mycoplasma spp., Bartonella spp., Rickettsia spp...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29554918/does-co-infection-with-vector-borne-pathogens-play-a-role-in-clinical-canine-leishmaniosis
#20
Marta Baxarias, Alejandra Álvarez-Fernández, Pamela Martínez-Orellana, Sara Montserrat-Sangrà, Laura Ordeix, Alicia Rojas, Yaarit Nachum-Biala, Gad Baneth, Laia Solano-Gallego
BACKGROUND: The severity of canine leishmaniosis (CanL) due to Leishmania infantum might be affected by other vector-borne organisms that mimic its clinical signs and clinicopathological abnormalities. The aim of this study was to determine co-infections with other vector-borne pathogens based on serological and molecular techniques in dogs with clinical leishmaniosis living in Spain and to associate them with clinical signs and clinicopathological abnormalities as well as disease severity...
March 20, 2018: Parasites & Vectors
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