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Capnocytophaga

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https://www.readbyqxmd.com/read/29786138/association-of-different-immunosuppressive-medications-with-periodontal-condition-in-patients-with-rheumatoid-arthritis-results-from-a-cross-sectional-study
#1
Dirk Ziebolz, Annegret Rupprecht, Jan Schmickler, Laura Bothmann, Juliane Krämer, Daniel Patschan, Gerhard A Müller, Rainer F Mausberg, Jana Schmidt, Gerhard Schmalz, Susann Patschan
BACKGROUND: The aim of this cross-sectional study was to investigate clinical periodontal findings as well as prevalence of selected potentially periodontal pathogenic bacteria in patients with rheumatoid arthritis (RA) treated with different immunosuppressive rheumatic medications. METHODS: 168 patients with RA undergoing different immunosuppressive medications were included and divided into subgroups according to their medication, which was taken in the past six months, in detail I) non-steroidal anti-inflammatory drugs (NSAID) and glucocorticoids combined, and II-VII) different disease modifying anti-rheumatic drugs (DMARDs): II) Methotrexate (MTX), III) Leflunomide, IV) MTX and TNF-α antagonists combined, V) Interleukin-6 (IL-6) antagonist, VI) MTX and Rituximab combined, and VII) combination therapies of more than two of these DMARDs...
May 22, 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29766330/laser-reduction-of-specific-microorganisms-in-the-periodontal-pocket-using-er-yag-and-nd-yag-lasers-a-randomized-controlled-clinical-study
#2
K Grzech-Leśniak, A Sculean, Boris Gašpirc
The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned into one of three treatment groups of 20 patients. The first group received scaling and root planing by hand instruments (SRP group), the second group received Er:YAG laser treatment alone (Er group), and the third group received combined treatment with Nd:YAG and Er:YAG lasers (NdErNd group)...
May 15, 2018: Lasers in Medical Science
https://www.readbyqxmd.com/read/29730383/fulminant-septic-shock-caused-by-capnocytophaga-canimorsus-in-italy-case-report
#3
Giorgio Piccinelli, Francesca Caccuri, Elena De Peri, Andrea Tironi, Silvia Odolini, Lucia Dora Notarangelo, Franco Gargiulo, Francesco Castelli, Nicola Latronico, Fabio Facchetti, Arnaldo Caruso
Capnocytophaga canimorsus infection was recently recognized as a zoonosis. We report the first case of fulminant septic shock in Italy caused by this pathogen. The patient, with a history of splenectomy, died at the main hospital in Brescia with a presumptive diagnosis of sepsis. PCR and sequencing on post mortem samples confirmed C. canimorsus as a causative organism. Our purpose is to alert medical professionals to the virulence of C. canimorsus in asplenic and immunocompromised patients.
May 3, 2018: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29706238/-a-fatal-septic-shock-due-to-capnocytophaga-canimorsus-and-review-of-literature
#4
G Vignon, P Combeau, J Violette, A-S Cognée, S Méglio, F Carrère, P Aucher, F Lellouche
INTRODUCTION: Capnocytophaga canimorsus is a Gram-negative bacterium present in normal dogs and cats mouths. It can be responsible for septic shocks after dog or cat bite, especially in asplenic patients. CASE REPORT: We report here a case of C. canimorsus infection rapidly presenting as a multiple organ dysfonction syndrome in an immunocompetent 54 years old patient, who lives near a dog, without any sign of bite. The evolution was a rapidly fatal fulminant septic shock...
April 26, 2018: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29703650/lung-abscess-following-bronchoscopy-due-to-multidrug-resistant-capnocytophaga-sputigena-adjacent-to-lung-cancer-with-high-pd-l1-expression
#5
Yohei Migiyama, Moriyasu Anai, Kosuke Kashiwabara, Yusuke Tomita, Sho Saeki, Kazuyoshi Nakamura, Shinichiro Okamoto, Hidenori Ichiyasu, Kazuhiko Fujii, Hirotsugu Kohrogi
Lung abscess following flexible bronchoscopy is a rare and sometimes fatal iatrogenic complication. Here, we report the first case of a lung abscess caused by multidrug-resistant Capnocytophaga sputigena following bronchoscopy. A 67-year-old man underwent bronchoscopy to evaluate a lung mass. Seven days after transbronchial lung biopsy, he presented with an abscess formation in a lung mass. Empirical antibiotic therapy, including with garenoxacin, ampicillin/sulbactam, clindamycin and cefepime, was ineffective...
April 24, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29696719/capnocytophaga-canimorsus-a-rare-case-of-conservatively-treated-prosthetic-valve-endocarditis
#6
Päivi Jalava-Karvinen, Juha O Grönroos, Helena Tuunanen, Jukka Kemppainen, Jarmo Oksi, Ulla Hohenthal
We describe a rare case of prosthetic valve endocarditis caused by the canine bacterium Capnocytophaga canimorsus in a male aged 73 years. The diagnosis of infective endocarditis was unequivocal, as it blood cultures were positive for C. canimorsus and vegetations were detected on transesophageal echocardiography; the modified Duke criteria were fulfilled. PET-CT showed intense 18 F-FDG uptake of the prosthetic valve area. The patient was treated with antibiotics alone (no surgery), and is now on life-long suppressive antibiotic therapy...
May 2018: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/29685983/gut-microbiome-analysis-identifies-potential-aetiological-factors-in-acute-gastroenteritis
#7
Natalia Castaño-Rodríguez, Alexander P Underwood, Juan Merif, Stephen M Riordan, William D Rawlinson, Hazel M Mitchell, Nadeem O Kaakoush
The morbidity and mortality resulting from acute gastroenteritis and associated chronic sequelae represent a substantial burden on health care systems worldwide. Few studies have investigated changes in the gut microbiome following an episode of acute gastroenteritis. Using non-directed 16S rRNA gene amplicon sequencing, the faecal microbiota of 475 patients with acute gastroenteritis was examined. Patient age was correlated to the overall microbial composition, with a decrease in Faecalibacterium observed in older patients...
April 23, 2018: Infection and Immunity
https://www.readbyqxmd.com/read/29680846/association-of-time-under-immunosuppression-and-different-immunosuppressive-medication-on-periodontal-parameters-and-selected-bacteria-of-patients-after-solid-organ-transplantation
#8
G Schmalz, L Berisha, H Wendorff, F Widmer, A Marcinkowski, H Teschler, U Sommerwerck, R Haak, O Kollmar, D Ziebolz
BACKGROUND: Aim of this study was to investigate the association of the time under immunosuppression and different immunosuppressive medication on periodontal parameters and selected periodontal pathogenic bacteria of immunosuppressed patients after solid organ transplantation (SOT). MATERIAL AND METHODS: 169 Patients after SOT (lung, liver or kidney) were included and divided into subgroups according their time under (0-1, 1-3, 3-6, 6-10 and >10 years) and form of immunosuppression (Tacrolimus, Cyclosporine, Mycophenolate, Glucocorticoids, Sirolimus and monotherapy vs...
April 22, 2018: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/29593919/double-native-valve-infective-endocarditis-due-to-capnocytophaga-canimorsus-first-reported-case-caused-by-a-lion-bite
#9
Mazin Barry
Capnocytophaga canimorsus is a Gram-negative bacilli that is part of the normal oral flora of dogs and some cats; it is well known to cause septicemia and endocarditis after their bite. This is the first reported case of infective endocarditis affecting both native mitral and aortic valves after a lion bite in a patient with heavy ethanol consumption, who ultimately died after valve replacements.
2018: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29576948/characterization-of-the-salivary-microbiome-in-people-with-obesity
#10
Yujia Wu, Xiaopei Chi, Qian Zhang, Feng Chen, Xuliang Deng
Background: The interactions between the gut microbiome and obesity have been extensively studied. Although the oral cavity is the gateway to the gut, and is extensively colonized with microbes, little is known about the oral microbiome in people with obesity. In the present study, we investigated the salivary microbiome in obese and normal weight healthy participants using metagenomic analysis. The subjects were categorized into two groups, obesity and normal weight, based on their BMIs...
2018: PeerJ
https://www.readbyqxmd.com/read/29566996/the-impact-of-chemotherapeutic-treatment-on-the-oral-microbiota-of-patients-with-cancer-a-systematic-review
#11
REVIEW
Kelly Rocio Vargas Villafuerte, Cristhiam de Jesus Hernandez Martinez, Felipe Torres Dantas, Helio Humberto Angotti Carrara, Francisco José Candido Dos Reis, Daniela Bazan Palioto
OBJECTIVE: Chemotherapy is a type of systemic treatment that inhibits neoplastic cells (cancer cells), produces immunosuppression, and may lead to changes in the oral mucosa and, consequently, in the oral microbiota. The aim of this systematic review was to analyze, in the scientific literature, evidence of the impact of chemotherapy on the oral microbiota. STUDY DESIGN: The authors conducted a search in PubMed/MEDLINE, Scientific Electronic Library Online (SciELO), LILACS, ScienceDirect, Web of Science, and Cochrane Library; to identify studies that discussed change in the oral microbiota of patients with during chemotherapy...
February 21, 2018: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29523423/capnocytophaga-canimorsus-an-emerging-pathogen-in-immunocompetent-patients-experience-from-an-emergency-department
#12
Nicole Bertin, Gabriele Brosolo, Fabrizio Pistola, Francesco Pelizzo, Christian Marini, Franco Pertoldi, Olga Vriz
BACKGROUND: Capnocytophaga canimorsus is a bacterium of the normal oral flora of dogs and cats. Human infection is caused by animal bite but is rarely observed, mainly in immunocompromised patients. We present 2 cases of C. canimorsus infection that occurred in immunocompetent patients and caused multiorgan failure and in both cases severe neurologic involvement. CASE REPORT: In the first case, we present a 69-year-old immunocompetent woman with septic shock derived from skin and soft tissue infection after a dog's bite...
March 6, 2018: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29520825/subgingival-microbial-profile-of-obese-women-with-periodontal-disease
#13
Carina M Silva-Boghossian, Paola C Cesário, Anna Thereza T Leão, Ana Paula V Colombo
BACKGROUND: This study compared the composition of subgingival microbiota between obese and non-obese women with or without periodontal disease. METHODS: Full-mouth periodontal clinical assessments were carried out in 76 obese women (17 periodontally healthy and 59 with periodontal disease), and 34 non-obese women (12 periodontally healthy, 22 with periodontal disease). Subgingival biofilm samples were individually obtained from seven sites of each individual, and the prevalence and counts of 40 bacterial taxa were determined by the checkerboard method...
February 2018: Journal of Periodontology
https://www.readbyqxmd.com/read/29487096/-barely-a-scratch-capnocytophaga-canimorsus-causing-prosthetic-hip-joint-infection-following-a-dog-scratch
#14
Irasha Hettiarachchi, Scott Parker, Sanjit Singh
Capnocytophaga canimorsus is a commensal organism commonly found in the oral cavity of cats and dogs. Infections with this organism are rare and can affect both immunocompetent and immunocompromised individuals. The authors present a case of C canimorsus causing indolent prosthetic hip joint infection in a healthy 66-year-old woman following a history of being scratched by her pet dog. The patient had an atypical history of chronic, low-grade infection which is unusual, as this organism is more frequently associated with acute presentations and fulminant sepsis...
February 27, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29360230/capnocytophaga-keratitis-in-dogs-clinical-histopathologic-and-microbiologic-features-of-seven-cases
#15
Eric C Ledbetter, Rebecca J Franklin-Guild, Michele L Edelmann
OBJECTIVE: To describe the clinical, microbiologic, and histopathologic features of Capnocytophaga keratitis in dogs. ANIMALS STUDIED: Seven dogs with naturally acquired Capnocytophaga keratitis. PROCEDURES: Medical records of dogs with a clinical diagnosis of keratitis and corneal cultures positive for Capnocytophaga spp. were reviewed. Dog signalment, medical history, clinical findings, and diagnostic assay results were recorded. RESULTS: Breeds included Boston terrier (n = 3 dogs), Rat terrier (n = 2), and single cases of mixed breed and Pug...
January 23, 2018: Veterinary Ophthalmology
https://www.readbyqxmd.com/read/29230499/-fulminant-sepsis-after-capnocytophaga-canimorsus-infection
#16
K Feige, Pia Hartmann, J T Lutz
Capnocytophaga canimorsus is a Gram-negative bacterium present in the oral cavities of cats and dogs. It is known for its capability to cause life-threatening sepsis following a dog bite, especially in immunocompromised patients. We report the case of a 67-year-old man who suffered from septic shock and multiorgan failure presumably following contamination of a pre-existing minor skin lesion by canine saliva. The purpose of this report is to raise awareness of Capnocytophaga canimorsus among physicians when faced with a patient presenting with fulminant septic shock and Gram-negative bacteremia, who has been exposed to dogs...
January 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/29181783/capnocytophaga-endodontalis-sp-nov-isolated-from-a-human-refractory-periapical-abscess
#17
Eojin Jo, Soon-Nang Park, Yun Kyong Lim, Jayoung Paek, Yeseul Shin, Hongik Kim, Si Hyun Kim, Jeong Hwan Shin, Young-Hyo Chang, Joong-Ki Kook
A novel Gram-negative, capnophilic, fusiform bacterium, designated strain ChDC OS43T , was isolated from a human refractory periapical abscess in the left mandibular second molar and was characterized by polyphasic taxonomic analysis. The 16S rRNA gene sequence revealed that the strain belongs to the genus Capnocytophaga, as it showed sequence similarities to Capnocytophaga ochracea ATCC 27872T (96.30%) and C. sputigena ATCC 33612T (96.16%). The prevalent fatty acids of strain ChDC OS43T were isoC15:0 (57.54%), C16:0 (5...
April 2018: Current Microbiology
https://www.readbyqxmd.com/read/29123842/severe-sepsis-caused-by-capnocytophaga-canimorsus-complicated-by-thrombotic-microangiopathy-in-an-immunocompetent-patient
#18
Shota Maezawa, Daisuke Kudo, Keiichiro Asanuma, Daisuke Takekoshi, Ryuichiro Egashira, Shigeki Kushimoto
Case: A 61-year-old man with an unremarkable medical history was admitted with fever 7 days after being bitten by his dog. On day 3, he showed altered mental status, and laboratory data showed progressive hemolytic anemia, thrombocytopenia, hyperbilirubinemia, renal dysfunction, coagulopathy, and schistocytosis. Severe sepsis complicated with thrombotic microangiopathy caused by Capnocytophaga canimorsus was suspected. Outcome: Plasma exchange was applied to treat the thrombotic microangiopathy and resulted in platelet count increase and improved renal function, hyperbilirubinemia, and schistocytosis...
January 2017: Acute Medicine & Surgery
https://www.readbyqxmd.com/read/29097460/twelve-complete-reference-genomes-of-clinical-isolates-in-the-capnocytophaga-genus
#19
Aaron Villarma, Christopher A Gulvik, Lori A Rowe, Mili Sheth, Phalasy Juieng, Ainsley C Nicholson, Vladimir N Loparev, John R McQuiston
We report here 1 near-complete genome sequence and 12 complete genome sequences for clinical Capnocytophaga isolates. Total read coverages ranged from 211× to 737×, and genome sizes ranged from 2.41 Mb to 3.10 Mb. These genomes will enable a more comprehensive taxonomic evaluation of the Capnocytophaga genus.
November 2, 2017: Genome Announcements
https://www.readbyqxmd.com/read/29093403/sepsis-caused-by-newly-identified-capnocytophaga-canis-following-cat-bites-c-canis-is-the-third-candidate-along-with-c-canimorsus-and-c-cynodegmi-causing-zoonotic-infection
#20
Minami Taki, Yoshio Shimojima, Ayako Nogami, Takuhiro Yoshida, Michio Suzuki, Koichi Imaoka, Hiroki Momoi, Norinao Hanyu
Sepsis caused by a Capnocytophaga canis infection has only been rarely reported. A 67-year-old female with a past medical history of splenectomy was admitted to our hospital with fever and general malaise. She had been bitten by a cat. She showed disseminated intravascular coagulation and multi-organ failure because of severe sepsis. On blood culture, characteristic gram-negative fusiform rods were detected; therefore, a Capnocytophaga species infection was suspected. A nucleotide sequence analysis revealed the species to be C...
January 15, 2018: Internal Medicine
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