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https://www.readbyqxmd.com/read/28931174/improvement-of-radiological-teaching-effects-of-focusing-of-learning-targets-and-increased-consideration-of-learning-theory-knowledge
#1
Stefan Wirth, York-Alexander William, Marco Paolini, Kathrin Wirth, Daniel Maxien, Maximilian Reiser, Martin R Fischer
Purpose Based on evaluation and examination results of students, a necessity for improvement of so far purely instructor-based radiological teaching at the local institution was determined. Aim of our study was to use one out of eight seminars to exemplify adaptation of the teaching concept according to learning theory knowledge, to determine the resulting effects and to interpret them. Materials and methods The institutional review board approved the prospective study of the seminar conversion, which was performed after the end of the winter semester 2015/2016...
September 20, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28931165/adolescents-and-young-adults-perceptions-of-electronic-cigarettes-as-a-gateway-to-smoking-a-qualitative-study-in-switzerland
#2
Christina Akre, Joan-Carles Suris
Electronic cigarettes (ECs) acting as a gateway to smoking traditional cigarettes (TCs) is a growing public health concern of EC use among youths. To gather the opinions and perceptions of adolescents and young adults (AYAs) on whether and how EC can act as a gateway to smoking TC among youths. A qualitative method included 42 AYAs. Participants identified a significant risk of EC acting as a gateway to TC use, several factors contributing to this phenomenon such as a facilitated transition to smoking or its perception as a harmless toy...
October 1, 2017: Health Education Research
https://www.readbyqxmd.com/read/28931133/a-descriptive-study-of-advising-practices-during-travel-health-consultations-in-france
#3
C Marchand, F Merrina, R Gagnayre, O Bouchaud
Background: Recommendations for improving traveler adherence address both the content of the advice given and the structure of the consultation. The objective of this article is to describe how travel health consultations are structured in France. Methods: A questionnaire based on both theoretical foundations and recommendations in the literature was sent to health professionals who practice in travel clinics, all of them members of France's Société de Médecine des Voyages...
September 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28931132/oxygen-saturation-increases-over-the-course-of-the-night-in-mountaineers-at-high-altitude-3050-6354-m
#4
Markus Tannheimer, Rianne van der Spek, Florian Brenner, Raimund Lechner, Jürgen M Steinacker, Gunnar Treff
Background: Blood oxygen saturation (SpO 2 ) is frequently measured to determine acclimatization status in high-altitude travellers. However, little is known about nocturnal time course of SpO 2 (SpO 2N ), but alterations in SpO 2N might be practically relevant as well. To this end, we describe the time-course of SpO 2N in mountaineers at high altitude. Methods: SpO 2N was continuously measured in ten male mountaineers during a three-week expedition in Peru (3,050-6,354m)...
September 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28931094/ethnicity-and-skin-autofluorescence-based-risk-engines-for-cardiovascular-disease-and-diabetes-mellitus
#5
Muhammad Saeed Ahmad, Torben Kimhofer, Sultan Ahmad, Mohammed Nabil AlAma, Hala Hisham Mosli, Salwa Ibrahim Hindawi, Dennis O Mook-Kanamori, Katarína Šebeková, Zoheir Abdullah Damanhouri, Elaine Holmes
Skin auto fluorescence (SAF) is used as a proxy for the accumulation of advanced glycation end products (AGEs) and has been proposed to stratify patients into cardiovascular disease (CVD) and diabetes mellitus (DM) risk groups. This study evaluates the effects of seven different ethnicities (Arab, Central-East African, Eastern Mediterranean, European, North African, South Asian and Southeast Asian) and gender on SAF as well as validating SAF assessment as a risk estimation tool for CVD and DM in an Arabian cohort...
2017: PloS One
https://www.readbyqxmd.com/read/28931089/advanced-glycation-end-products-dietary-restriction-effects-on-bacterial-gut-microbiota-in-peritoneal-dialysis-patients-a-randomized-open-label-controlled-trial
#6
Rabi Yacoub, Melinda Nugent, Weijin Cai, Girish N Nadkarni, Lee D Chaves, Sham Abyad, Amanda M Honan, Shruthi A Thomas, Wei Zheng, Sujith A Valiyaparambil, Mark A Bryniarski, Yijun Sun, Michael Buck, Robert J Genco, Richard J Quigg, John C He, Jaime Uribarri
The modern Western diet is rich in advanced glycation end products (AGEs). We have previously shown an association between dietary AGEs and markers of inflammation and oxidative stress in a population of end stage renal disease (ESRD) patients undergoing peritoneal dialysis (PD). In the current pilot study we explored the effects of dietary AGEs on the gut bacterial microbiota composition in similar patients. AGEs play an important role in the development and progression of cardiovascular (CVD) disease. Plasma concentrations of different bacterial products have been shown to predict the risk of incident major adverse CVD events independently of traditional CVD risk factors, and experimental animal models indicates a possible role AGEs might have on the gut microbiota population...
2017: PloS One
https://www.readbyqxmd.com/read/28930995/stereotactic-atlas-guided-laser-capture-microdissection-of-brain-regions-affected-by-traumatic-injury
#7
Harris A Weisz, Deborah R Boone, Stacy L Sell, Helen L Hellmich
The ability to isolate specific brain regions of interest can be impeded in tissue disassociation techniques that do not preserve their spatial distribution. Such techniques also potentially skew gene expression analysis because the process itself can alter expression patterns in individual cells. Here we describe a laser capture microdissection (LCM) method to selectively collect specific brain regions affected by traumatic brain injury (TBI) by using a modified Nissl (cresyl violet) staining protocol and the guidance of a rat brain atlas...
September 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28930941/thoracic-irrigation-prevents-retained-hemothorax-a-prospective-propensity-scored-analysis
#8
Nathan W Kugler, Thomas W Carver, David Milia, Jasmeet S Paul
BACKGROUND: Thoracic trauma resulting in hemothorax (HTx) is typically managed with thoracostomy tube (TT) placement; however, up to 20% of patients develop retained HTx which may necessitate further intervention for definitive management. While optimal management of retained HTx has been extensively researched, little is known about prevention of this complication. We hypothesized thoracic irrigation at the time of TT placement would significantly decrease the rate of retained HTx necessitating secondary intervention...
September 20, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28930931/multiple-concomitant-traumatic-pseudoaneurysms-of-the-superficial-temporal-artery
#9
Doga Gurkanlar, Sevda Lafci Fahrioğlu
The authors present a case with a 22-year-old man suffering from a 2 pseudoaneurysms at the temporal region following trauma. The second pseudoaneurysm was diagnosed through an astute use of digital subtraction angiography along with ultrasound to the right external carotid artery which was preferred due to the presence of a vascular pathology at the region of the trauma. During surgery, the distal and proximal ends of both aneurysms were ligated and resected. The concomitant pseudoaneurysms and the use of digital subtraction angiography should be kept in mind in such trauma patients to prevent additional surgical interventions...
September 19, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28930919/2017-military-supplement-mini-review-perfluorocarbons-oxygen-transport-and-microcirculation-in-low-flow-states-in-vivo-and-in-vitro-studies
#10
Ivo P Torres Filho
The in vivo study of microvascular oxygen transport requires accurate and challenging measurements of several mass transfer parameters. Although recommended, blood flow and oxygenation are typically not measured in many studies where treatments for ischemia are tested. Therefore, the aim of this communication is to briefly review cardinal aspects of oxygen transport, and the effects of perfluorocarbon treatment on blood flow and oxygenation based mostly on studies performed in our laboratory. Since physiologically relevant events in oxygen transport take place at the microvascular level, we implemented the phosphorescence quenching technique coupled with non-invasive intravital videomicroscopy for quantitative evaluation of these events in vivo...
September 19, 2017: Shock
https://www.readbyqxmd.com/read/28930918/neutrophil-to-lymphocyte-ratio-predicts-death-in-acute-on-chronic-liver-failure-patients-admitted-to-the-intensive-care-unit-a-retrospective-cohort-study
#11
Nicolas Moreau, Xavier Wittebole, Yvan Fleury, Patrice Forget, Pierre-François Laterre, Castanares-Zapatero Diego
The neutrophil-to-lymphocyte ratio (NLR) is an inflammation score recognized as associated with outcome. While inflammation has been shown to correlate with the development of acute-on-chronic liver failure (ACLF), we sought to investigate the role of NLR in predicting 90-day mortality in cirrhotic patients experiencing ACLF.We performed a retrospective cohort study involving a total of 108 consecutive cirrhotic patients admitted in the intensive care unit (ICU). NLR, clinical and biological data were recorded...
September 19, 2017: Shock
https://www.readbyqxmd.com/read/28930878/performance-of-future-elite-players-at-the-nfl-scouting-combine
#12
David P Hedlund
The purpose of this study is to examine players' physical and performance measures taken at the NFL Scouting Combine and compare these to their future performance in the NFL. From 2002-2016, three types of player data (N=5,506) were collected from secondary data sources. Results players earned on various NFL Scouting Combine drills and measurements (e.g., height, weight, 40-yard dash time, vertical jump, bench press repetitions, shuttle run time, and 3-cone drill time), the position players play on the field (e...
September 11, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28930852/does-body-shadow-improve-the-efficacy-of-virtual-reality-based-training-with-bts-nirvana-a-pilot-study
#13
Margherita Russo, Rosaria De Luca, Antonino Naro, Francesca Sciarrone, Bianca Aragona, Giuseppe Silvestri, Alfredo Manuli, Alessia Bramanti, Carmela Casella, Placido Bramanti, Rocco Salvatore Calabrò
BACKGROUND: Aim of the present study was to evaluate whether the presence of body shadows during virtual reality (VR) training with BTS NIRVANA (BTs-N) may lead to a better functional recovery. METHODS: We enrolled 20 poststroke rehabilitation inpatients, who underwent a neurocognitive-rehabilitative training consisting of 24 sessions (3 times a week for 8 weeks) of BTs-N. All the patients were randomized into 2 groups: semi-immersive virtual training with (S-IVTS group) or without (S-IVT group) body shadows...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930846/cancer-risk-in-patients-with-diabetic-nephropathy-a-retrospective-cohort-study-in-hong-kong
#14
Chi Yuen Cheung, Maggie Kam Man Ma, Wai Leung Chak, Sydney Chi Wai Tang
Diabetic nephropathy (DN) is a leading cause of end-stage kidney disease nowadays. Certain cancers are more common in patients with diabetes mellitus. However, there are no data concerning the cancer pattern in patients with DN. The aim of this study is to investigate the site-specific cancer risk and mortality in these patients.A retrospective cohort study of 5643 DN patients between 2000 and 2015 was conducted in 2 large hospitals in Hong Kong. Incidence and mortality of various cancers were compared with those of general population using standardized incidence ratios (SIRs) and standardized mortality ratios (SMRs) respectively...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930815/variability-in-usual-care-mechanical-ventilation-for-pediatric-acute-respiratory-distress-syndrome-time-for-a-decision-support-protocol
#15
Christopher J L Newth, Katherine A Sward, Robinder G Khemani, Kent Page, Kathleen L Meert, Joseph A Carcillo, Thomas P Shanley, Frank W Moler, Murray M Pollack, Heidi J Dalton, David L Wessel, John T Berger, Robert A Berg, Rick E Harrison, Richard Holubkov, Allan Doctor, J Michael Dean, Tammara L Jenkins, Carol E Nicholson
OBJECTIVES: Although pediatric intensivists philosophically embrace lung protective ventilation for acute lung injury and acute respiratory distress syndrome, we hypothesized that ventilator management varies. We assessed ventilator management by evaluating changes to ventilator settings in response to blood gases, pulse oximetry, or end-tidal CO2. We also assessed the potential impact that a pediatric mechanical ventilation protocol adapted from National Heart Lung and Blood Institute acute respiratory distress syndrome network protocols could have on reducing variability by comparing actual changes in ventilator settings to those recommended by the protocol...
September 19, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28930803/safety-of-fertility-sparing-surgery-for-premenopausal-women-with-sex-cord-stromal-tumors-confined-to-the-ovary
#16
Dimitrios Nasioudis, Melissa K Frey, Eloise Chapman-Davis, Steven S Witkin, Kevin Holcomb
OBJECTIVE: The aim of this retrospective population-based study was to investigate the oncologic safety of fertility-sparing surgery (FSS) for premenopausal women with malignant sex cord-stromal tumors (SCSTs) confined to the ovary. METHODS: A cohort of women aged 18 to 49 years and diagnosed with a stage I malignant SCST between 1984 and 2013 was drawn from the National Cancer Institute's Surveillance, Epidemiology, and End Results database. Based on site-specific surgery codes, women who had FSS, defined as unilateral oophorectomy/tumor resection without hysterectomy, and definite surgery were identified...
September 19, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28930714/vaccine-exemptions-and-the-church-state-problem
#17
Dena S Davis
All of the 50 states of the United States have laws governing childhood vaccinations; 48 allow for religious exemptions, while 19 also offer exemptions based on some sort of personal philosophy. Recent disease outbreaks have caused these states to reconsider philosophical exemptions. However, we cannot, consistent with the U.S. Constitution, give preference to religion by creating religious exemptions only. The Constitution requires states to put religious and nonreligious claims on equal footing. Given the ubiquity of nonreligious objections to vaccination, I conclude that the best response is to remove all exemptions, as two states have already done...
2017: Journal of Clinical Ethics
https://www.readbyqxmd.com/read/28930703/nine-lessons-from-ashley-and-her-parents
#18
Edmund G Howe
Parents' love for their child, even a child who has severe impairments, may give them much joy and quality in their life. This is also the case for caregivers of adults with severe cognitive impairments, such as end-stage dementia. How can clinicians work with these parents and caregivers and help them?
2017: Journal of Clinical Ethics
https://www.readbyqxmd.com/read/28930678/dna-ligase-iv-guides-end-processing-choice-during-nonhomologous-end-joining
#19
Michael P Conlin, Dylan A Reid, George W Small, Howard H Chang, Go Watanabe, Michael R Lieber, Dale A Ramsden, Eli Rothenberg
Nonhomologous end joining (NHEJ) must adapt to diverse end structures during repair of chromosome breaks. Here, we investigate the mechanistic basis for this flexibility. DNA ends are aligned in a paired-end complex (PEC) by Ku, XLF, XRCC4, and DNA ligase IV (LIG4); we show by single-molecule analysis how terminal mispairs lead to mobilization of ends within PECs and consequent sampling of more end-alignment configurations. This remodeling is essential for direct ligation of damaged and mispaired ends during cellular NHEJ, since remodeling and ligation of such ends both require a LIG4-specific structural motif, insert1...
September 19, 2017: Cell Reports
https://www.readbyqxmd.com/read/28930639/50-years-of-research-in-ards-tidal-volume-selection-in-the-acute-respiratory-distress-syndrome
#20
Sarina K Sahetya, Jordi Mancebo, Roy G Brower
Mechanical ventilation (MV) is critical in the management of many patients with the acute respiratory distress syndrome (ARDS). However, MV can also cause ventilator-induced lung injury (VILI). The selection of an appropriate tidal volume is an essential part of a lung-protective MV strategy. Since the publication of a large randomized clinical trial demonstrating the benefit of lower tidal volumes, the use of tidal volumes of 6 mL/kg predicted body weight (PBW, based on sex and height) has been recommended in clinical practice guidelines...
September 20, 2017: American Journal of Respiratory and Critical Care Medicine
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