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https://www.readbyqxmd.com/read/28430519/energy-resolved-ultrashort-delays-of-photoelectron-emission-clocked-by-orthogonal-two-color-laser-fields
#1
Xiaochun Gong, Cheng Lin, Feng He, Qiying Song, Kang Lin, Qinying Ji, Wenbin Zhang, Junyang Ma, Peifen Lu, Yunquan Liu, Heping Zeng, Weifeng Yang, Jian Wu
A phase-controlled orthogonal two-color (OTC) femtosecond laser pulse is employed to probe the time delay of photoelectron emission in the strong-field ionization of atoms. The OTC field spatiotemporally steers the emission dynamics of the photoelectrons and meanwhile allows us to unambiguously distinguish the main and sideband peaks of the above-threshold ionization spectrum. The relative phase shift between the main and sideband peaks, retrieved from the phase-of-phase of the photoelectron spectrum as a function of the laser phase, gradually decreases with increasing electron energy, and becomes zero for the fast electron which is mainly produced by the rescattering process...
April 7, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28428126/interactions-of-tetracyclines-with-ovalbumin-the-main-allergen-protein-from-egg-white-spectroscopic-and-electrophoretic-studies
#2
Maria Dayanne de A Dantas, Humberto de Araújo Tenório, Thiago Inácio B Lopes, Hugo Juarez V Pereira, Anita J Marsaioli, Isis M Figueiredo, Josué Carinhanha Caldas Santos
The interactions of tetracycline (TC), oxytetracycline (OTC) and chlortetracycline (CTC) with ovalbumin (OVA), the main allergen protein of egg white, were investigated by molecular spectroscopy and electrophoresis at three pH conditions (1.5, 4.6 and 7.4). Molecular and synchronous fluorescence, UV-vis spectroscopy, electrophoresis and (1)H NMR were used to study the interaction process. Tetracyclines interact with ovalbumin fluorescence by a static quenching mechanism with non-fluorescent complex formation changing the native protein structure...
April 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28419077/otc-fluticasone-furoate-nasal-spray-flonase-sensimist-for-allergic-rhinitis
#3
(no author information available yet)
No abstract text is available yet for this article.
April 24, 2017: Medical Letter on Drugs and Therapeutics
https://www.readbyqxmd.com/read/28412281/assessing-the-exploratory-and-anxiety-related-behaviors-of-mice-do-different-caging-systems-affect-the-outcome-of-behavioral-tests
#4
Alexia Polissidis, Sofia Zelelak, Maria Nikita, Pavlos Alexakos, Marianna Stasinopoulou, Zacharias-Ioannis Kakazanis, Nikolaos Kostomitsopoulos
Ample studies have shown that housing can affect the health, welfare and behavior of mice and therefore, the outcomes of certain experiments. The aim of this study was to investigate if three widely used housing systems, Open Top Cages (OTC), Motor Free Ventilated Cages (MFVC) and Individually Ventilated Cages (IVC) may affect exploratory and anxiety-related behaviors in mice. Subjects were 8week-old male C57Bl/6J mice (n=36) divided into three groups, OTC, IVC and MFVC groups, respectively. The experimental procedure consisted of two behavioral tests: the open field and the elevated plus maze test...
April 12, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28405552/over-the-counter-and-prescription-medications-for-acne-a-cross-sectional-survey-in-a-sample-of-university-students-in-saudi-arabia
#5
Mohja D Alshehri, Abdulsalam T Almutairi, Asma M Alomran, Batool A Alrashed, Feroze Kaliyadan
INTRODUCTION AND BACKGROUND: Acne is a very common dermatological condition found among the adolescent population in Saudi Arabia. Many patients with acne try various forms of self-medication, over the counter medicines (OTC), and prescription medicines for the same. MATERIALS AND METHODS: This was a cross-sectional study among university students in the Kingdom of Saudi Arabia (KSA). A validated questionnaire was distributed to a convenience sample of university students to evaluate their knowledge and attitudes towards OTC (mainly) as well as prescription medicine for acne...
March 2017: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/28399319/factors-associated-with-potentially-inappropriate-medication-use-in-rural-community-dwelling-older-adults
#6
Marcia Y Shade, Ann M Berger, Claudia Chaperon, Gleb Haynatzki, Linda Sobeski, Bernice Yates
Potentially inappropriate medication (PIM) use is a serious public health problem in older adults because it may lead to adverse events. The purpose of the current study was to explore PIM use in rural, community-dwelling older adults. Participants (N = 138) underwent one-on-one medication reviews. Approximately one half (49%) of the sample used prescribed and over-the-counter (OTC) PIM. Prescribed and OTC nonsteroidal anti-inflammatory drugs (33%) and anticholinergic medications (28%) were the most frequently used PIM...
April 11, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/28398023/clinical-profile-of-women-with-vva-who-are-not-candidates-for-local-vaginal-oestrogen-therapy
#7
Rossella E Nappi, Filippo Murina, Giuseppina Perrone, Paola Villa, Nicoletta Biglia
Vulvar and vaginal atrophy (VVA) is a chronic medical condition in postmenopausal women, which is predominantly due to a permanent cessation of ovarian oestrogen production. Current available treatment options for VVA are over-the-counter (OTC) symptomatic relief products or local oestrogen therapy (LET) aiming to treat this underlying atrophic condition. Recent surveys indicated that these products decrease sexual spontaneity, are messy and indiscrete. Ospemifene is an oral daily drug, which has proven to treat vaginal dryness and dyspareunia effectively...
April 10, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28395772/an-electrochemical-aptasensor-for-multiplex-antibiotics-detection-using-y-shaped-dna-based-metal-ions-encoded-probes-with-nmof-substrate-and-csrp-target-triggered-amplification-strategy
#8
Meng Chen, Ning Gan, Tianhua Li, Ye Wang, Qing Xu, Yinji Chen
An effective electrochemical aptasensor has been developed for the detection of multiplex antibiotics using Y-shaped DNA probes. These probes-based metal ions encoded the nanoscale metal-organic frameworks (NMOF) as a substrate, and circular strand-replacement DNA polymerization (CSRP) target triggered the amplification strategy. The Y-DNA probes (Y-DNA) were assembled using an assisted DNA probe (assisted DNA labeled with magnetic gold nanoparticles) which can hybridize to the captured DNA probe (consisting of aptamer and primer recognition region), and signal tags (NMOF encapsulating signal DNAs and different metal ions such as Pb(2+) or Cd(2+))...
May 22, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28391658/otc-medical-abortion-to-be-or-not-to-be
#9
Kamheang Chaturachinda
The article by Kapp et al summarizing further research to move early medical pregnancy termination over the counter (OTC) is timely and appropriate. Universal access over the counter of this 'silver bullet', de facto de-medicalisation of early abortion would save a large number of maternal deaths and spare women from the debility from unsafe abortion worldwide. It would greatly improve women's reproductive health (Rosenfield A. Int J Gynaecol Obstet 1994; 46: 173-179). Easy access to safe abortion would also benefit women in remote and rural area as well as urban ones (Jones RK et al...
April 9, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28366039/efficacy-and-safety-of-an-over-the-counter-1-colloidal-oatmeal-cream-in-the-management-of-mild-to-moderate-atopic-dermatitis-in-children-a-double-blind-randomized-active-controlled-study
#10
Toni Anne Lisante, Chris Nuñez, Paul Zhang
PURPOSE: The purpose of this study is to evaluate the efficacy and safety of an over-the-counter (OTC) 1% colloidal oatmeal cream versus a prescription barrier cream in children with mild-to-moderate atopic dermatitis (AD). MATERIALS AND METHODS: Eligible patients (6 months-18 years) were randomized to OTC or prescription cream. Eczema Area and Severity Index (EASI) scores, Investigator's Global Atopic Dermatitis Assessment (IGADA) scores, patients' and/or caregivers' assessment of itch using 10-cm visual analog scale (VAS) on day 0, weeks 1, 2, and 3 were assessed...
April 2, 2017: Journal of Dermatological Treatment
https://www.readbyqxmd.com/read/28364318/reassessing-the-ecology-of-medical-care-in-japan
#11
Tsuguya Fukui, Mahbubur Rahman, Sachiko Ohde, Eri Hoshino, Takeshi Kimura, Kevin Y Urayama, Fumio Omata, Gautam A Deshpande, Osamu Takahashi
Studies on ecology of medical care can provide valuable information on how people seek healthcare in a specific geographic area. The objective of this study was to update a 2003 report on the ecology of medical care in Japan, identifying relevant changes in healthcare patterns. We collected information based on a prospective health diary recorded for a month in 2013 (n = 4548; 3787 adults and 797 children) using a population-weighted random sample from a nationally representative panel. We compared our overall and stratified findings with a similar study conducted in 2003...
March 31, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28363560/nanocellulose-crystals-derivative-silica-hybrid-sol-open-tubular-capillary-column-for-enantioseparation
#12
Shuqing Dong, Yaming Sun, Xia Zhang, Hui Li, Guoying Luo, Liang Zhao
Broad spectrum separation of chiral compounds is a challenge task for analysts. It is significant for preparation of chiral stationary phase and selection of separation technology in the field. Here, we present a novel nanocellulose crystals (NCCs) which were derivation with 3,5-dimethylphenyl isocynate (DMPC) and silane with 3-triethoxysilylpropylisocyanate form sol in tetraethylorthosilicate (TEOS) and layer-by-layer self-assembly in the inner of capillary to fabricate the organic-inorganic hybrid open tubular capillary column (DMPC/NCCs-OTC) for enantiomers separation by capillary electrochromatography technology (CEC)...
June 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28358386/lack-of-pregnancy-warnings-on-over-the-counter-dermatologic-products-containing-potentially-harmful-hydroquinone
#13
L L Bio, J J Cies
OBJECTIVE: To determine the presence of pregnancy warnings on over-the-counter (OTC) dermatologic products with hydroquinone, a potentially harmful ingredient. STUDY DESIGN: Data were obtained from the Food and Drug Administration National Drug Code Directory and Label Repository to identify OTC dermatologic products containing hydroquinone. Products were stratified based on pregnancy or general warning presence (WP) or absence (WA). Product characteristics were compared between groups: hydroquinone concentration, presence of external packaging, indication and warning statements...
March 30, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/28356767/efficacy-and-safety-of-guaifenesin-for-upper-back-neck-and-shoulder-pain-a-phase-ii-proof-of-concept-multicenter-placebo-controlled-repeat-dose-parallel-group-study
#14
Agron Collaku, Yong Yue, Kenneth Reed
BACKGROUND/OBJECTIVE: Guaifenesin, an over-the-counter (OTC) expectorant, has exhibited muscle relaxant effects preclinically and clinically. This proof-of-principle study explored whether OTC doses of guaifenesin can provide relief from acute upper back, neck, or shoulder muscle spasm and pain. METHODS: This multicenter, placebo-controlled, repeat-dose, parallel study randomly assigned adults experiencing acute pain and muscle spasm in their upper back, neck, or shoulder to guaifenesin 600 or 1200 mg or matched placebo twice daily (BID) in a 2:2:1:1 ratio for 7 days...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28352949/from-prescription-only-rx-to-over-the-counter-otc-status-in-germany-2006-2015-pharmacological-perspectives-on-regulatory-decisions
#15
Eva Barrenberg, Edeltraut Garbe
PURPOSE: Little is known about the extent of switches from prescription-only (Rx) to over-the-counter (OTC) status in Europe and about the pharmacological properties of the switched substances. The objectives of this study were to provide an overview of the substances that were switched from Rx to OTC status in Germany between 2006 and 2015 and to assess their pharmacological properties. METHODS: Session minutes of the German Expert Advisory Committee for Prescription-Only Issues, changes to the German Ordinance on Prescription-Only Medicines and the Summary of Product Characteristics of the switched substances were analysed...
March 28, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28349341/knowledge-and-opinion-of-pharmacists-on-emergency-contraceptive-pills-in-hungary
#16
Melinda Vanya, Maria Matuz, Ria Benko, Reka Viola, Attila Horvath-Sziklai, Gyongyvér Soos, Gyorgy Bartfai
Background Emergency contraceptive pills (ECPs) are used to prevent unintended pregnancy. There is a worldwide intention to improve access to ECPs; therefore, identifying potential barriers to introducing over-the counter (OTC) access is of utmost importance. As pharmacists are the key personnel to convey accurate drug information, their knowledge and attitude on ECPs is important. Objective We aimed to conduct a nationwide study to assess pharmacists' knowledge on ECPs and to survey their opinion on sales category change of ECPs (i...
March 27, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28349216/does-warming-by-open-top-chambers-induce-change-in-the-root-associated-fungal-community-of-the-arctic-dwarf-shrub-cassiope-tetragona-ericaceae
#17
Kelsey Erin Lorberau, Synnøve Smebye Botnen, Sunil Mundra, Anders Bjørnsgaard Aas, Jelte Rozema, Pernille Bronken Eidesen, Håvard Kauserud
Climate change may alter mycorrhizal communities, which impact ecosystem characteristics such as carbon sequestration processes. These impacts occur at a greater magnitude in Arctic ecosystems, where the climate is warming faster than in lower latitudes. Cassiope tetragona (L.) D. Don is an Arctic plant species in the Ericaceae family with a circumpolar range. C. tetragona has been reported to form ericoid mycorrhizal (ErM) as well as ectomycorrhizal (ECM) symbioses. In this study, the fungal taxa present within roots of C...
March 27, 2017: Mycorrhiza
https://www.readbyqxmd.com/read/28346150/factors-contributing-to-poor-satisfaction-with-sleep-and-healthcare-seeking-behavior-in-older-adults
#18
Olufunmilola Abraham, Jia Pu, Loren J Schleiden, Steven M Albert
OBJECTIVE: To identify factors influencing older adults' poor satisfaction with sleep and their current healthcare seeking behaviors. DESIGN: Cross-sectional study. SETTING: Pittsburgh Claude D. Pepper Older Americans Independence Center Community Registry. PARTICIPANTS: Individuals aged 60 or older enrolled in the registry that completed a cross-sectional mailed survey (N = 1026). MEASUREMENTS: Participant demographics (age, gender, marital status, race, education), overall health (self-rated health, pain, and comorbidities), and health behaviors (physical activity, smoking, drinking behaviors) were collected from the registry database...
February 2017: Sleep Health
https://www.readbyqxmd.com/read/28340706/layer-by-layer-self-assembly-of-gold-nanoparticles-thiols-%C3%AE-cyclodextrin-coating-as-the-stationary-phase-for-enhanced-chiral-differentiation-in-open-tubular-capillary-electrochromatography
#19
Lin-Lin Fang, Ping Wang, Xiao-Li Wen, Xin Guo, Lin-da Luo, Jia Yu, Xing-Jie Guo
The popularity of capillary electrochromatography (CEC) has led to an increasing number of studies on the development and evaluation of enantioselective CEC systems. Herein, a novel, simple, and economical method for the preparation of chiral stationary phases for enantioselective open tubular capillary electrochromatography (OTCEC) was reported for the first time. This novel capillary column was fabricated through layer-by-layer self-assembly of GNPs on a 3-mercaptopropyl-trimethoxysilane (MPTMS)-modified fused-silica capillary and subsequent surface functionalization of the GNPs through self-assembly of thiols β-cyclodextrin (SH-β-CD)...
May 15, 2017: Talanta
https://www.readbyqxmd.com/read/28333228/efficacy-of-ovarian-tissue-cryopreservation-for-fertility-preservation-lessons-learned-from-545-cases
#20
P Jadoul, A Guilmain, J Squifflet, M Luyckx, R Votino, C Wyns, M M Dolmans
STUDY QUESTION: How effective is ovarian tissue cryopreservation (OTC)? SUMMARY ANSWER: In our cohort of patients who underwent OTC, premature ovarian failure (POF) rates, return rates and pregnancy rates after autotransplantation were 31.5, 4.4 and 33%, respectively. WHAT IS KNOWN ALREADY: OTC for fertility purposes has been performed for >20 years now. With over 86 live births reported worldwide and success rates of ~30% after autotransplantation of frozen-thawed ovarian cortex, the procedure should no longer be considered experimental...
May 1, 2017: Human Reproduction
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