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https://www.readbyqxmd.com/read/28639423/emergency-contraceptive-pill-users-risk-perceptions-for-sexually-transmitted-infections-and-future-unintended-pregnancy
#1
Mary T Hickey, Michele G Shedlin
BACKGROUND AND PURPOSE: The availability of emergency contraception pills (ECP) over the counter (OTC) has the potential to reduce the incidence of unintended pregnancy; however, the increased risk for sexually transmitted infection (STI) acquisition, related to unprotected intercourse, has not been adequately addressed. The purpose of this study is to gain insight into risk perceptions for STIs and subsequent unintended pregnancy in women who have purchased ECP OTC. METHODS: Twenty-one women, aged 18-24, attending a private university in an urban setting, who purchased and used ECP OTC participated in 1-h, individual interviews...
June 22, 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/28637073/-complementary-and-alternative-medicine-in-oncology-what%C3%A2-makes-sense
#2
Axel Eustachi, Dieter Melchart
The basis of any complementary therapy should be the recommendation of a healthy lifestyle (diet, nutrition, exercise, stress-reduction), and appropriate self-help techniques (e. g. thermotherapy, herbal OTC-products) aimed at releasing the patients' most debilitating symptoms. For therapy-resistant or strong symptoms, more invasive interventions or medical treatments with an acceptable evidence base can be used (e. g. acupuncture for cancer pain, herbal prescriptions). The effects of any complementary intervention should be controlled for a period of six weeks after its administration...
June 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28629602/management-of-dentin-hypersensitivity-by-practitioners-in-the-national-dental-practice-based-research-network
#3
Dorota T Kopycka-Kedzierawski, Cyril Meyerowitz, Mark S Litaker, Marc W Heft, Nirmala Tasgaonkar, Marianne R Day, Andretta Porter-Williams, Valeria V Gordan, Robin L Yardic, Timothy M Lawhorn, Gregg H Gilbert
BACKGROUND: Dentin hypersensitivity (DH) is a condition commonly encountered in clinical dental practice. The authors conduct a study to identify the treatments recommended to manage DH among dentists in the United States. METHODS: The authors conducted a multicenter study of 1,862 patients with DH who received a diagnosis and were treated by 171 dentists with the National Dental Practice-Based Research Network. RESULTS: The most common treatment recommended was desensitizing over-the-counter (OTC) potassium nitrate toothpaste (alone or in combination with other treatments) for 924 of 1,862 patients (50%)...
June 16, 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28627413/modeling-esophagitis-using-human-three-dimensional-organotypic-culture-system
#4
Dorottya Laczkó, Fang Wang, F Bradley Johnson, Nirag Jhala, András Rosztóczy, Gregory G Ginsberg, Gary W Falk, Anil K Rustgi, John P Lynch
Esophagitis, whether caused by acid reflux, allergic responses, graft-versus-host disease, drugs, or infections, is a common condition of the gastrointestinal tract affecting nearly 20% of the US population. The instigating agent typically triggers an inflammatory response. The resulting inflammation is a risk factor for the development of esophageal strictures, Barrett esophagus, and esophageal adenocarcinoma. Research into the pathophysiology of these conditions has been limited by the availability of animal and human model systems...
June 13, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28624639/ozone-exposure-and-flux-based-response-relationships-with-photosynthesis-leaf-morphology-and-biomass-in-two-poplar-clones
#5
Bo Shang, Zhaozhong Feng, Pin Li, Xiangyang Yuan, Yansen Xu, Vicent Calatayud
Poplar clones 546 (P. deltoides cv. '55/56'×P. deltoides cv. 'Imperial') and 107 (P. euramericana cv. '74/76') were exposed to five ozone concentrations in 15 open-top chambers (OTCs). Both ozone exposure (AOT40, Accumulation Over a Threshold hourly ozone concentration of 40ppb) and flux-based (POD7, Phytotoxic Ozone Dose above an hourly flux threshold of 7nmol O3 m(-2) PLA (projected leaf area) s(-1)) response relationships were established with photosynthesis, leaf morphology and biomass variables. Increases in both metrics showed significant negative relationships with light-saturated photosynthesis rate, chlorophyll content, leaf mass per area, actual photochemical efficiency of PSII in the light and root biomass but not with stomatal conductance (gs), leaf and stem biomass...
June 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28599186/histological-alterations-in-gills-and-liver-of-rainbow-trout-oncorhynchus-mykiss-after-exposure-to-the-antibiotic-oxytetracycline
#6
S Rodrigues, S C Antunes, B Nunes, A T Correia
The aim of this study was to investigate the histopathological effects of oxytetracycline (OTC) on the gill and liver tissues of rainbow trouts (Oncorhynchus mykiss) following acute (96h: 0.005-50mg/L) and chronic (28days: 0.3125-5μg/L) exposures. Results suggest the existence of a cause-and-effect relationship between the exposure to OTC and tissue damage. Most predominant disorders observed in gills were progressive (e.g. hypertrophy of mucous cells and hyperplasia of epithelial cells) in acute exposure and regressive (e...
May 27, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28597531/attitudes-in-australia-on-the-upscheduling-of-over-the-counter-codeine-to-a-prescription-only-medication
#7
Jacqui McCoy, Raimondo Bruno, Suzanne Nielsen
INTRODUCTION AND AIMS: In December 2016, the Australian Therapeutic Goods Administration announced that over-the-counter (OTC) codeine would be available by prescription-only in February 2018. Prior to this announcement, the authors aimed to evaluate attitudes among Australian codeine consumers, pharmacists and general medical practitioners (GP) towards the proposed upscheduling of OTC codeine. DESIGN AND METHODS: Public Therapeutic Goods Administration submissions on codeine upscheduling were assessed, and a brief questionnaire was developed to assess the common issues raised...
June 8, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28597413/late-onset-ornithine-transcarbamylase-deficiency-associated-with-hyperammonemia
#8
Kana Daijo, Tomokazu Kawaoka, Takashi Nakahara, Yuko Nagaoki, Masataka Tsuge, Akira Hiramatsu, Michio Imamura, Yoshiiku Kawakami, Hiroshi Aikata, Keiichi Hara, Go Tajima, Masao Kobayashi, Kazuaki Chayama
The urea cycle converts ammonia and produces urea. One form of urea cycle abnormality is ornithine transcarbamylase (OTC) deficiency. This hereditary disorder is associated with hyperammonemia. OTC deficiency commonly appears during neonatal and early childhood life and is rare in adults. We report a 69-year-old man who presented at the local hospital with 3-day loss of appetite, early morning vomiting, and state of confusion. Blood ammonia was 293 μg/dl. At 2-3 h after admission, the patient went into a deep coma...
June 9, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/28587476/do-the-new-fda-guidance-documents-help-improving-performance-of-blood-glucose-monitoring-systems-compared-with-iso-15197
#9
Guido Freckmann, Annette Baumstark, Stefan Pleus
Recently, the Food and Drug Administration (FDA) published guidance documents for point-of-care testing (POCT) and over-the-counter (OTC) blood glucose monitoring systems (BGMS). These are expected to improve weaknesses of the already established ISO 15197:2013 standard accuracy evaluation for OTC BGMS; however, the proposed criteria and procedures rather raise new questions. As an example, the OTC guidance stipulates tighter accuracy criteria in the low glycemic range than the POCT guidance for no obvious reason...
June 1, 2017: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/28585409/a-population-based-study-of-risk-perceptions-of-paracetamol-use-among-swedes-with-a-special-focus-on-young-adults
#10
H Håkonsen, T Hedenrud
PURPOSE: The purpose of this study was to investigate risk perceptions of paracetamol use, with a special focus on young adults. METHODS: A web survey was sent to a representative sample (n = 5838) of the Swedish adult population. Altogether, 3120 persons answered the full questionnaire. Risk perceptions of paracetamol use in relation to sex, age, and education were determined using logistic regression. RESULTS: Most respondents (70.5%) reported use of paracetamol in the 3 months prior to the study; the highest proportion was found among those aged 18 to 25 years (75...
June 5, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28578167/novel-label-free-and-high-throughput-microchip-electrophoresis-platform-for-multiplex-antibiotic-residues-detection-based-on-aptamer-probes-and-target-catalyzed-hairpin-assembly-for-signal-amplification
#11
Ye Wang, Ning Gan, You Zhou, Tianhua Li, Futao Hu, Yuting Cao, Yinji Chen
Novel label-free and multiplex aptasensors have been developed for simultaneous detection of several antibiotics based on a microchip electrophoresis (MCE) platform and target catalyzed hairpin assembly (CHA) for signal amplification. Kanamycin (Kana) and oxytetracycline (OTC) were employed as models for testing the system. These aptasensors contained six DNA strands termed as Kana aptamer-catalysis strand (Kana apt-C), Kana inhibit strand (Kana inh), OTC aptamer-catalysis strand (OTC apt-C), OTC inhibit strand (OTC inh), hairpin structures H1 and H2 which were partially complementary...
May 10, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28577467/ag-agcl-nanoparticles-modified-cdsno3%C3%A2-3h2o-nanocubes-photocatalyst-for-the-degradation-of-methyl-orange-and-antibiotics-under-visible-light-irradiation
#12
Shi-Feng Yang, Cheng-Gang Niu, Da-Wei Huang, Huan Zhang, Guang-Ming Zeng
CdSnO3·3H2O (CSH) nanocubes modified with Ag/AgCl nanoparticles were constructed via the ultrasonic-assisted precipitation-photoreduction method. The obtained samples were characterized using various analytical techniques. Methyl orange (MO), tetracycline (TC), and oxytetracycline hydrochloride (OTC-HCl) were degraded as target pollutants under visible light irradiation to evaluate the photocatalytic activity of the as-prepared samples. Compared with pure CSH and Ag/AgCl nanoparticles, the developed composite of which 5mL of AgNO3 was added on the synthesis, labelled as 5-Ag/AgCl/CSH, occupied the best photocatalytic activity...
May 28, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28566722/community-and-species-specific-responses-of-plant-traits-to-23-years-of-experimental-warming-across-subarctic-tundra-plant-communities
#13
Gaurav Baruah, Ulf Molau, Yang Bai, Juha M Alatalo
To improve understanding of how global warming may affect competitive interactions among plants, information on the responses of plant functional traits across species to long-term warming is needed. Here we report the effect of 23 years of experimental warming on plant traits across four different alpine subarctic plant communities: tussock tundra, Dryas heath, dry heath and wet meadow. Open-top chambers (OTCs) were used to passively warm the vegetation by 1.5-3 °C. Changes in leaf width, leaf length and plant height of 22 vascular plant species were measured...
May 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28555782/stepwise-partitioning-of-xp21-a-profiling-method-for-xk-deletions-causative-of-the-mcleod-syndrome
#14
Christoph Gassner, Chantal Brönnimann, Yvonne Merki, Maja P Mattle-Greminger, Sonja Sigurdardottir, Eduardo Meyer, Charlotte Engström, John D O'Sullivan, Hans H Jung, Beat M Frey
BACKGROUND: McLeod syndrome (MLS) is hematologically defined by the absence of the red blood cell (RBC) antigen Kx on the transmembrane RBC protein, XK, representing a highly specific diagnostic marker. Direct molecular assessment of XK therefore represents a desirable diagnostic tool. Whereas pathogenic point mutations may be simply identified, partial and complete deletions of XK on Xp21.1, eventually covering adjacent genes and causing multifaceted "continuous gene syndromes," are difficult to localize...
May 28, 2017: Transfusion
https://www.readbyqxmd.com/read/28553093/applications-of-direct-to-consumer-hearing-devices-for-adults-with-hearing-loss-a-review
#15
REVIEW
Vinaya Manchaiah, Brian Taylor, Ashley L Dockens, Nicole R Tran, Kayla Lane, Mariana Castle, Vibhu Grover
BACKGROUND: This systematic literature review is aimed at investigating applications of direct-to-consumer hearing devices for adults with hearing loss. This review discusses three categories of direct-to-consumer hearing devices: 1) personal sound amplification products (PSAPs), 2) direct-mail hearing aids, and 3) over-the-counter (OTC) hearing aids. METHOD: A literature review was conducted using EBSCOhost and included the databases CINAHL, MEDLINE, and PsycINFO...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/28546037/developing-alternative-over-the-counter-medicine-label-formats-how-do-they-compare-when-evaluated-by-consumers
#16
Vivien Tong, David K Raynor, Parisa Aslani
BACKGROUND: In recent years, the Australian Therapeutic Goods Administration (TGA) has proposed implementing a standardized over-the-counter (OTC) medicine label. However, there were mixed consumer opinions regarding a label proposed in 2012 and limited evidence demonstrating the usability of the revised (2014) format. OBJECTIVE: To develop and examine the usability of alternative OTC medicine label formats for standardization, and explore consumer perspectives on the labels...
March 9, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28544204/receipt-and-use-of-spoken-and-written-over-the-counter-medicine-information-insights-into-australian-and-uk-consumers-experiences
#17
Vivien Tong, David K Raynor, Parisa Aslani
OBJECTIVES: To explore Australian and UK consumers' receipt and use of spoken and written medicine information and examine the role of leaflets for consumers of over-the-counter (OTC) medicines. METHODS: Semistructured interviews were conducted with 37 Australian and 39 UK consumers to explore information received with their most recent OTC medicine purchase, and how information was used at different times post-purchase. Interviews were audio-recorded, transcribed verbatim and thematically analysed...
May 24, 2017: International Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/28535485/quantification-of-residual-antibiotics-in-cow-manure-being-spread-over-agricultural-land-and-assessment-of-their-behavioral-effects-on-antibiotic-resistant-bacteria
#18
Ji-Ran Yeom, Soon-Uk Yoon, Chang-Gyun Kim
Antibiotic resistant bacteria (ARB) in livestock manure used as fertilizer and spread over agriculture land, may pose a threat to the health of humans. Considering this, the concentrations of tetracycline (TC), oxytetracycline (OTC), and sulfathiazole (STZ) in the surface soil were quantified using LC-MS. These antibiotics have been used in livestock and are found in fertilizer produced from livestock excretions. Species of ABR were identified using 16S rDNA. Soil samples were collected at depths of 0, 7, and 15 cm from farmland in Incheon (South Korea)...
May 16, 2017: Chemosphere
https://www.readbyqxmd.com/read/28535353/broad-specificity-immunoassay-for-simultaneous-detection-of-ochratoxins-a-b-and-c-in-millet-and-maize
#19
Yaqiong Zhang, Lanteng Wang, Xing Shen, Xiaoqun Wei, Xinan Huang, Yingju Liu, Xiulan Sun, Zhanhui Wang, Yuanming Sun, Zhenlin Xu, Sergei A Eremin, Hongtao Lei
Ochratoxins A, B, and C (OTA, OTB, and OTC) can be found in cereals and feeds; the simultaneous detection of these ochratoxins holds a great need in food safety. In this study, four antibodies raised from two ochrotoxin haptens and two coating antigens were compared, and then a sensitive and broad-specificity enzyme-linked immunosorbent assay (ELISA) was established for the simultaneous determination of three ochratoxins, where the detection limits were 0.005, 0.001, and 0.001 ng/mL for OTA, OTB, and OTC, respectively, and recoveries of three ochratoxins were between 84...
June 5, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28533689/medication-related-costs-of-rhinitis-in-australia-a-nostradata-cross-sectional-study-of-pharmacy-purchases
#20
Pete Smith, David Price, Richard Harvey, Andrew Simon Carney, Vicky Kritikos, Sinthia Z Bosnic-Anticevich, Louise Christian, Derek Skinner, Victoria Carter, Alice Marie Sybille Durieux
PURPOSE: There is a relative paucity of research regarding medication expenditure associated with multiple-therapy use for rhinitis in Australia. To describe 1) the nature and extent of multiple-therapy use for rhinitis in Australia using data on therapies purchased with prescription or over-the-counter (OTC) and 2) additional costs incurred by multiple-therapy use compared with intranasal corticosteroid (INCS) therapy alone. PATIENTS AND METHODS: A retrospective observational study was carried out using a database containing anonymous pharmacy transaction data available from 20% of pharmacies in Australia that links doctor prescriptions and OTC purchase information...
2017: Journal of Asthma and Allergy
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