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https://www.readbyqxmd.com/read/29029072/detection-of-optra-in-the-african-continent-tunisia-within-a-mosaic-enterococcus-faecalis-plasmid-from-urban-wastewaters
#1
Ana R Freitas, Houyem Elghaieb, Ricardo León-Sampedro, Mohamed Salah Abbassi, Carla Novais, Teresa M Coque, Abdennaceur Hassen, Luisa Peixe
Objectives: Oxazolidinone resistance is a serious limitation in the treatment of MDR Enterococcus infections. Plasmid-mediated oxazolidinone resistance has been strongly linked to animals where the use of phenicols might co-select resistance to both antibiotic families. Our goal was to assess the diversity of genes conferring phenicol/oxazolidinone resistance among diverse enterococci and to characterize the optrA genetic environment. Methods: Chloramphenicol-resistant isolates (>16 mg/L, n = 245) from different sources (hospitals/healthy humans/wastewaters/animals) in Portugal, Angola and Tunisia (1996-2016) were selected...
September 26, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29028100/zeb1-promotes-prostate-cancer-proliferation-and-invasion-through-erk1-2-signaling-pathway
#2
X-F Song, H Chang, Q Liang, Z-F Guo, J-W Wu
OBJECTIVE: Prostate cancer is a kind of malignancy with high occurrence in the male urogenital system. However, the mechanism of the occurrence, the progression, and the metastasis of prostate cancer are still unclear. Searching for the effective molecule target is of great significance to improve the curative effect on prostate cancer. Zinc finger E box binding protein-1 (ZEB1) protein is a member of the zinc finger transcription factor family that participates in the embryonic development and formation...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29026290/mindfulness-training-for-psychological-stress-in-family-caregivers-of-persons-with-dementia-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#3
REVIEW
Zheng Liu, Qian-Lin Chen, Yu-Ying Sun
Caring for a relative with dementia is extremely challenging; conventional interventions may not be highly effective or easily available on some occasions. This study aimed to explore the efficacy of mindfulness training in improving stress-related outcomes in family caregivers of people with dementia using a meta-analytic review. We searched randomized controlled trials (RCT) through April 2017 from five electronic databases, and assessed the risk of bias using the Cochrane Collaboration tool. Seven RCTs were included in our review...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29025800/approach-to-recurrent-fever-in-childhood
#4
REVIEW
Gordon S Soon, Ronald M Laxer
OBJECTIVE: To provide an approach to recurrent fever in childhood, explain when infections, malignancies, and immunodeficiencies can be excluded, and describe the features of periodic fever and other autoinflammatory syndromes. SOURCES OF INFORMATION: PubMed was searched for relevant articles regarding the pathogenesis, clinical findings, diagnosis, prognosis, and treatment of periodic fever and autoinflammatory syndromes. MAIN MESSAGE: Fever is a common sign of illness in children and is most frequently due to infection...
October 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/29025489/evidence-based-interventions-to-reduce-tuberculosis-stigma-a-systematic-review
#5
N Sommerland, E Wouters, E M H Mitchell, M Ngicho, L Redwood, C Masquillier, R van Hoorn, S van den Hof, A Van Rie
SETTING: While substantial progress is being made in tuberculosis (TB) control, the success of public health efforts is hampered by pervasive stigma. OBJECTIVE: To perform a systematic literature review to assess the effectiveness of interventions aimed at reducing TB stigma in patients, health care workers, care givers and the general community. DESIGN: Studies were eligible for inclusion if they evaluated interventions aimed at reducing TB stigma and were published between 1950 and 2015...
November 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/29025128/opioid-therapy-for-chronic-pain-overview-of-the-2017%C3%A2-us-department-of-veterans-affairs-and-us-department-of-defense-clinical-practice-guideline
#6
Jack M Rosenberg, Brandon M Bilka, Sara M Wilson, Christopher Spevak
Description: The US Department of Veterans Affairs (VA) and US Department of Defense (DoD) revised the 2010 clinical practice guideline (CPG) for the management of opioid therapy for chronic pain, considering the specific needs of the VA and DoD and new evidence regarding prescribing opioid medication for non-end-of-life-related chronic pain. This paper summarizes the major recommendations and compares them with the US Centers for Disease Control and Prevention (CDC) guideline for prescribing opioids...
September 1, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29025093/discharge-communication-practices-and-healthcare-provider-and-patient-preferences-satisfaction-and-comprehension-a-systematic-review
#7
Harvey Newnham, Anna Barker, Edward Ritchie, Karen Hitchcock, Harry Gibbs, Sara Holton
Purpose: To systematically review the available evidence about hospital discharge communication practices and identify which practices were preferred by patients and healthcare providers, improved patient and provider satisfaction, and increased patients' understanding of their medical condition. Data sources: OVID Medline, Web of Science, ProQuest, PubMed and CINAHL plus. Study selection: Databases were searched for peer-reviewed, English-language papers, published to August 2016, of empirical research using quantitative or qualitative methods...
September 7, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29024808/critical-care-nurses-experiences-of-withdrawal-of-treatment-a-systematic-review-of-qualitative-evidence
#8
REVIEW
Brandi Vanderspank-Wright, Nikolaos Efstathiou, Amanda D Vandyk
BACKGROUND: Death and dying is a reality of the clinical context of the intensive care unit. Death often follows a decision to withdraw life-sustaining treatments. Critical care nurses, are the primary care providers to patients and families at the end-of-life in the intensive care unit. OBJECTIVE: To synthesize qualitative evidence on the experiences of critical care nurses who have cared for patients and families throughout the process of withdrawal of life-sustaining treatment...
September 28, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29024390/pollination-in-the-chilean-mediterranean-type-ecosystem-a-review-of-current-advances-and-pending-tasks
#9
REVIEW
R Medel, C González-Browne, F E Fontúrbel
We conducted a systematic review of the scientific literature published on plant-pollinator interactions, from both the plant and pollinator perspective, in the Chilean Mediterranean-type ecosystem (MTE hereafter). Our search identified 69 published papers on 235 native plant species from 62 families. Less than 7.9% of the flowering species inhabiting the Chilean Mediterranean have been studied, and most studies were restricted to only one locality and one reproductive season. The geographic location of the studies differed from a random pattern, showing two well-defined areas where most studies were conducted...
October 10, 2017: Plant Biology
https://www.readbyqxmd.com/read/29023923/treatment-abandonment-in-children-with-cancer-in-sub-saharan-africa-systematic-literature-review-and-meta-analysis
#10
REVIEW
Rikka Mansell
AIMS: To establish and quantify the main reasons for treatment abandonment in children with cancer in Sub-Saharan Africa through a systematic review of the literature. BACKGROUND: Great advances have been made in the treatment of childhood cancer, however this requires that families are able to complete treatment. Failure to do this is referred to as treatment abandonment, which is recognised as a reason for treatment failure. DESIGN: Systematic review and meta-analysis of data on the reasons for treatment abandonment in Sub-Saharan Africa...
October 11, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29023590/de-novo-assembly-and-analysis-of-the-transcriptome-of-rumex-patientia-l-during-cold-stress
#11
Jianxin Liu, Yongqing Xu, Liguo Zhang, Wei Li, Zhenxue Cai, Fei Li, Mu Peng, Fenglan Li, Baozhong Hu
BACKGROUND: Rumex patientia L. is consumed as a green vegetable in several parts of the world, and can withstand extremely low temperatures (-35°C). However, little or no available genomic data for this species has been reported to date. Here, we used Illumina Hiseq technology for transcriptome assembly in R. patientia under normal and cold conditions to evaluate how it responds to cold stress. RESULTS: After an in-depth RNA-Seq analysis, 115,589 unigenes were produced from the assembled transcripts...
2017: PloS One
https://www.readbyqxmd.com/read/29023134/a-systematic-review-of-correlates-of-depression-among-older-chinese-and-korean-immigrants-what-we-know-and-do-not-know
#12
Man Guo, Meredith Stensland
OBJECTIVES: Guided by the stress and coping theory, this study provides a systematic review of existing research on acculutration, family support, and social support related correlates of depression among older Chinese and Korean immigrants in the United States. METHOD: A comprehensive literature search was conducted in CINAHL Plus, Abstracts in Social Gerontology, AgeLine, Social Work Abstracts, PubMed, PsychINFO, and Social Science Citation Index databases to identify relevant articles that presented multivariate analysis results...
October 12, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29022410/use-of-amplatzer-occluders-for-treatment-of-aorto-pulmonary-fistulas-case-and-review-of-the-literature
#13
Petr Toušek, Viktor Kočka, Robert Petr, Jaroslav Ulman, Jan Hlavička, Miroslav Kolesár
the use of amplatzer occluder family in daily clinical practice has already overcome on-label indications, with growing clinical experience and the technological evolution of devices. Areas covered: We present the case of a patient with a very rare complication following proximal aortic surgery treated using a unique strategy. A huge pseudoaneurysm around an ascending aortic prosthesis ruptured into the right pulmonary artery. A hybrid treatment strategy consisting of percutaneous closure of the fistula followed by cardiosurgery was chosen due to the patient's poor haemodynamic condition...
October 12, 2017: Expert Review of Medical Devices
https://www.readbyqxmd.com/read/29022402/antibiotics-exposure-and-risk-of-inflammatory-bowel-disease-a-systematic-review
#14
Nikoletta A Theochari, Anastasios Stefanopoulos, Konstantinos S Mylonas, Konstantinos P Economopoulos
AIM: The aim of this study was to critically assess all available evidence suggesting an association between antibiotic exposure and new onset of inflammatory bowel disease (IBD). MATERIALS AND METHODS: This systematic review was conducted according to the PRISMA statement and eligible studies were identified through search of PubMed, Embase and the Cochrane Library. Data on patient demographics, antibiotic exposure and confounding factors were analyzed. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of eligible studies...
October 12, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29022094/transcriptomic-changes-in-echinochloa-colona-in-response-to-treatment-with-the-herbicide-imazamox
#15
Alice A Wright, Rajkumar Sasidharan, Liisa Koski, Marianela Rodriguez-Carres, Daniel G Peterson, Vijay K Nandula, Jeffery D Ray, Jason A Bond, David R Shaw
Presented here is the first Echinochloa colona leaf transcriptome. Analysis of gene expression before and after herbicide treatment reveals that E. colona mounts a stress response upon exposure to herbicide. Herbicides are the most frequently used means of controlling weeds. For many herbicides, the target site is known; however, it is considerably less clear how plant gene expression changes in response to herbicide exposure. In this study, changes in gene expression in response to herbicide exposure in imazamox-sensitive (S) and- resistant (R) junglerice (Echinochloa colona L...
October 11, 2017: Planta
https://www.readbyqxmd.com/read/29021838/qualitative-analysis-of-parkinson-s-disease-information-on-social-media-the-case-of-youtube%C3%A2
#16
Ibrahim Saleh Al-Busaidi, Tim J Anderson, Yassar Alamri
INTRODUCTION: There is a paucity of data pertaining to the usefulness of information presented on social media platforms on chronic neuropsychiatric conditions such as Parkinson's disease (PD). The aim of this study was to examine the quality of YouTube™ videos that deliver general information on PD and the availability and design of instructional videos addressing the caregiving role in PD. METHODS: YouTube™ was searched using the keyword "Parkinson's disease" for relevant videos...
September 2017: EPMA Journal
https://www.readbyqxmd.com/read/29021837/the-bssg-rat-model-of-parkinson-s-disease-progressing-towards-a-valid-predictive-model-of-disease
#17
REVIEW
Jackalina M Van Kampen, Harold A Robertson
ABSTRACT: Parkinson's disease (PD) is a neurodegenerative disorder, classically considered a movement disorder. A great deal is known about the anatomical connections and neuropathology and pharmacological changes of PD, as they relate to the loss of dopaminergic function and the appearance of cardinal motor symptoms. Our understanding of the role of dopamine in PD has led to the development of effective pharmacological treatments of the motor symptoms in the form of dopamine replacement therapy using levodopa and dopaminergic agonists...
September 2017: EPMA Journal
https://www.readbyqxmd.com/read/29021750/cough-anal-reflex-may-be-the-expression-of-a-pre-programmed-postural-action
#18
Paolo Cavallari, Francesco Bolzoni, Roberto Esposti, Carlo Bruttini
When coughing, an involuntary contraction of the external anal sphincter occurs, in order to prevent unwanted leakages or sagging of the pelvis muscular wall. Literature originally described such cough-anal response as a reflex elicited by cough, therefore identifying a precise cause-effect relationship. However, recent studies report that the anal contraction actually precedes the rise in abdominal pressure during cough expiratory effort, so that the sphincter activity should be pre-programmed. In recent years, an important family of pre-programmed muscle activities has been well documented to precede voluntary movements: these anticipatory actions play a fundamental role in whole body and segmental postural control, hence they are referred to as anticipatory postural adjustments (APAs)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29021126/healthydads-ca-what-do-men-want-in-a-website-designed-to-promote-emotional-wellness-and-healthy-behaviors-during-the-transition-to-parenthood
#19
Deborah Da Costa, Phyllis Zelkowitz, Nicole Letourneau, Andrew Howlett, Cindy-Lee Dennis, Brian Russell, Steven Grover, Ilka Lowensteyn, Peter Chan, Samir Khalifé
BACKGROUND: Up to 18% of men experience depression and/or anxiety during the transition to parenthood. Interventions designed specifically to promote the mental health of men during the transition to parenthood are scarce. Internet-delivered interventions may be acceptable and far-reaching in enhancing mental health, parenting knowledge, and healthy behaviors in expectant or new fathers. OBJECTIVE: To guide the development of Healthydads.ca, a website designed to enhance mental health and healthy behaviors in expectant fathers, a needs assessment was conducted to identify fathers' perspectives of barriers to seeking help for emotional wellness, informational needs, and factors affecting the decision to visit such a website...
October 11, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29020844/nucleoside-nucleotide-analogues-in-the-treatment-of-chronic-hepatitis-b-infection-during-pregnancy-a-systematic-review
#20
Soheil Tavakolpour, Mohammad Darvishi, Hajar Sadat Mirsafaei, Mojtaba Ghasemiadl
BACKGROUND: Women of childbearing age who have developed chronic hepatitis B (CHB) infection, especially HBeAg-positive highly viraemic pregnant women, are largely responsible for the familial transmission of the infection. Therefore, choosing the most effective and safest antiviral medications to manage pregnant CHB patients is of crucial importance. MATERIALS AND METHODS: The PubMed and Scopus databases were searched through September 2017, for all the journal articles possessing original results regarding treatment of CHB pregnant women with any nucleos(t)ide analogue (NA) therapies, including lamivudine (LAM), adefovir (ADV), entecavir (ETV), telbivudine (LdT), and tenofovir (TDF)...
October 11, 2017: Infectious Diseases
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