Jing Lian, Dongxin Lin, Yuchan Huang, Xiaohui Chen, Lian Chen, Fan Zhang, Peiling Tang, Jinling Xie, Xiaotao Hou, Zhengcai Du, Jiagang Deng, Erwei Hao, Junhui Liu
Tumours do not exist in isolation from the organism; their growth, proliferation, motility, and immunosuppressive response are intricately connected to the tumour's microenvironment. As tumour cells and the microenvironment coevolve, an inflammatory microenvironment ensues, propelling the phenomenon of inflammation-cancer transformation-an idea proposed by modern medicine. This review aims to encapsulate the array of representative factors within the tumour's inflammatory microenvironment, such as interleukins (IL-6, IL-10, IL-17, IL-1β), transforming growth factor-beta (TGF-β), interferon-gamma (IFN-γ), tumour necrosis factor-alpha (TNF-α), vascular endothelial growth factor (VEGF), and matrix metalloproteinases (MMPs)...
September 23, 2023: Chinese Medicine