keyword
https://read.qxmd.com/read/38416678/global-diversity-of-enterococci-and-description-of-18-previously-unknown-species
#21
JOURNAL ARTICLE
Julia A Schwartzman, Francois Lebreton, Rauf Salamzade, Terrance Shea, Melissa J Martin, Katharina Schaufler, Aysun Urhan, Thomas Abeel, Ilana L B C Camargo, Bruna F Sgardioli, Janira Prichula, Ana Paula Guedes Frazzon, Gonzalo Giribet, Daria Van Tyne, Gregg Treinish, Charles J Innis, Jaap A Wagenaar, Ryan M Whipple, Abigail L Manson, Ashlee M Earl, Michael S Gilmore
Enterococci are gut microbes of most land animals. Likely appearing first in the guts of arthropods as they moved onto land, they diversified over hundreds of millions of years adapting to evolving hosts and host diets. Over 60 enterococcal species are now known. Two species, Enterococcus faecalis and Enterococcus faecium, are common constituents of the human microbiome. They are also now leading causes of multidrug-resistant hospital-associated infection. The basis for host association of enterococcal species is unknown...
March 5, 2024: Proceedings of the National Academy of Sciences of the United States of America
https://read.qxmd.com/read/38414785/whipple-s-disease-of-the-respiratory-system-a-case-report
#22
Yue Deng, Hongmei Zhang, Junyu Lu, Zhiyu Zhou, Ting Zhang, Xuerong Cui
Whipple's disease (WD) is a multiple-system chronic disease caused by Tropheryma whipplei ( T. whipplei ) infection. The present study describes 3 cases of WD with clinical manifestations of cough, chest pain, headache, dyspnea, sputum, joint pain, abdominal pain, diarrhea and weight loss. Chest computed tomography (CT) showed signs of plaques, nodules and pleural thickening; and bronchoscopic alveolar lavage fluid metagenomic-sequencing indicated that it was T. whipplei . One patient was treated with meropenem as the starting regimen and two patients were treated with ceftriaxone as the starting regimen...
April 2024: Experimental and Therapeutic Medicine
https://read.qxmd.com/read/38414013/the-hospital-costs-of-complications-following-major-abdominal-surgery-a-retrospective-cohort-study
#23
JOURNAL ARTICLE
Angelica Armellini, Shaun Chew, Samuel Johnston, Vijayaragavan Muralidharan, Mehrdad Nikfarjam, Laurence Weinberg
OBJECTIVE: Postoperative complications following major abdominal surgeries is a pressing concern for hospital care and health economics. Given the paucity of available cost data for patients undergoing major abdominal surgery, we evaluated the number and the severity of postoperative complications following major abdominal surgeries and calculated the costs borne by a single centre university hospital within an Australian healthcare system. RESULTS: The overall incidence of postoperative complications for 1790 adult patients undergoing major abdominal surgeries (i...
February 27, 2024: BMC Research Notes
https://read.qxmd.com/read/38402412/a-40-year-old-man-with-a-7-year-history-of-polyarthritis-and-a-late-diagnosis-of-whipple-disease-a-journey-to-resolve-the-mystery
#24
JOURNAL ARTICLE
Gagan Aulakh, Rebekah Lewis, Arshdeep Singh, Valentin Marian
BACKGROUND Whipple disease (WD) is rare, with an incidence of only a few patients per million. It is caused by infection with the gram-positive bacterium Tropheryma whipplei, and presents with symptoms that include joint pain, fever, diarrhea, and weight loss. This report is of a 40-year-old man with a 7-year history of polyarthritis and a late diagnosis of Whipple disease. The atypical nature of his symptoms led to misdirection and misdiagnosis for years. CASE REPORT A middle-aged white man with seronegative migratory polyarticular arthritis underwent 7 years of treatment with steroids, disease-modifying anti-rheumatic drugs (DMARDs), and a TNF (tumor necrosis factor)-alpha inhibitor, all without any clinical improvement...
February 25, 2024: American Journal of Case Reports
https://read.qxmd.com/read/38347376/immune-recovery-uveitis-in-whipple-s-disease-an-unusual-ocular-presentation
#25
JOURNAL ARTICLE
Hippolyte Lequain, Stéphane Abramowicz, Julien Seiller, Amro Abukhashbah, Carole Burillon, Emmanuelle Vignot, Olivier Brunet, Pascal Sève
PURPOSE: To describe an unusual case of Whipple's disease (WD) complicated by uveitis, and subsequent paradoxical worsening after effective antibiotic treatment targeting Tropheryma whipplei (TW). METHODS: Case report. RESULTS: A 53-year-old male presented with bilateral knee arthritis, weight loss, chronic low-grade fever, and cognitive disorders. He was under treatment with tumor necrosis factor α inhibitors (TNFi) for seronegative spondyloarthritis...
February 13, 2024: Journal of Ophthalmic Inflammation and Infection
https://read.qxmd.com/read/38344639/whipple-s-disease-a-challenging-diagnosis
#26
Beatriz Porteiro, Ana Rita Freitas, Filipa Nunes, Marinela Major, Frederico Batista
Whipple's disease (WD) is a chronic multisystemic infection caused by Tropheryma whipplei . It is a rare condition with a wide spectrum of clinical presentations, necessitating a high clinical suspicion to arrive at the diagnosis. We present the case of a 65-year-old woman who experienced chronic, intermittent, and migratory polyarthralgia, weight loss, anorexia, and pyrosis. She was admitted due to bilateral deep vein thrombosis (DVT). She exhibited lymphadenopathy without hepatosplenomegaly, and lymph node biopsy revealed reactive lymphadenitis with intrahistiocytic bacilli that reacted positively to periodic acid-Schiff staining...
January 2024: Curēus
https://read.qxmd.com/read/38327972/intussusception-of-gastrojejunostomy-after-pancreatoduodenectomy-with-billroth-ii-reconstruction
#27
Alejandro Martinez-Esteban, Natalia M Barron-Cervantes, Pablo Avila-Sanchez, Carlos Chan-Nuñez
Gastrojejunal anastomosis or gastrojejunostomy (GJ) is a surgical procedure used for allowing gastric emptying, especially in cases where complex reconstructions are needed. One of the less common complications but one of the most relevant in morbidity is the intussusception of the GJ. It requires a high index of suspicion, preoperative optimization of the patient, diagnostic corroboration, and identification of associated complications with the use of contrasted imaging. It was described for the first time by Bozzi in 1914; currently, multiple cases have been described in the literature, being more frequent in bariatric surgeries and reconstructions after distal gastrectomy...
January 2024: Curēus
https://read.qxmd.com/read/38317655/how-to-start-and-build-a-practice-in-microsurgical-breast-reconstruction-success-and-sustainability-in-a-private-practice-setting
#28
JOURNAL ARTICLE
Steven M Pisano, Oscar Ochoa, Andrew A Gassman, Peter R Ledoux, Chet L Nastala, Lauren A Whipple, Gary I Arishita, Minas T Chrysopoulo
The aim of this article is to provide a template for building and sustaining a microsurgical breast reconstruction practice in a private practice setting. The target audience including residents, microsurgical fellows, and reconstructive microsurgeons were currently employed in an academic setting, and reconstructive microsurgeons were currently employed in a private group entity. We present five pillars that initiate, support, and sustain a successful practice in microsurgical breast reconstruction. The five key concepts are (1) establishing a practice vision and culture, (2) obtaining funding, (3) assembling staff, (4) negotiating insurance and other contracts, and (5) striving for efficiency and sustainability...
February 2024: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38292831/revolutionary-transformation-lowering-the-mortality-of-pancreaticoduodenectomy-a-historical-review
#29
JOURNAL ARTICLE
Bo Chang Wu, Jakub Wlodarczyk, Sanaz Nourmohammadi Abadchi, Niloufar Shababi, John L Cameron, John W Harmon
The History Maker paper focuses on the extraordinary revolution that dramatically improved the surgical results for the Whipple procedure (pancreaticoduodenectomy) in the 1980s and identifies Dr. Cameron as the leader of this revolution, who reported a mortality rate of approximately 1%. The revolutionary reduction of postoperative mortality for the Whipple procedure was achieved by adherence to gentle and precise Halstedian surgical techniques with adequate drainage of pancreatico-jejunal anastomosis with closed-suction silastic drains, along with the development of high-volume surgeons and hospitals...
September 2023: eGastroenterology
https://read.qxmd.com/read/38292808/posterior-fossa-microcystic-meningioma-mimicking-an-arachnoid-cyst
#30
James Bridges, Jared Brougham, Danielle Terrell, Stephen Whipple, Sungho Lee
Microcystic meningioma is an uncommon subtype of World Health Organization grade 1 meningiomas often associated with a shorter progression-free survival. Diagnosis through imaging alone can often be challenging due to atypical characteristics, especially when found in unexpected locations. Here, we present a 55-year-old woman who was diagnosed, based on imaging, with a posterior fossa arachnoid cyst 5 years prior after complaints of headaches and gait imbalance. After surgical resection of the "arachnoid cyst," the diagnosis of microcystic meningioma was made...
April 2024: Radiology Case Reports
https://read.qxmd.com/read/38283730/unraveling-the-whipple-triad-non-islet-cell-tumor-induced-hypoglycemia
#31
Farzahna Mohamed, Frederick J Raal
Tumor-induced hypoglycemia (TIH) is a rare paraneoplastic phenomenon resulting from several tumor types and mechanisms. Insulinomas are the most common cause of TIH. However, non-islet cell tumors can also trigger hypoglycemia by releasing insulin-like growth factor 2 (IGF-II) or its precursor. We present a case of a 56-year-old woman experiencing spontaneous hypoglycemia due to a pleural-based solitary fibrous tumor. Diagnostic evaluations revealed diminished C-peptide levels, increased IGF-II, and a 4-fold increase in the IGF-II: IGF-I ratio, indicative of non-islet cell tumor hypoglycemia...
February 2024: JCEM Case Rep
https://read.qxmd.com/read/38277984/pancreatic-duct-stones-treated-by-whipple-as-a-last-resort-a-case-report
#32
Usra I Ghanem, Peter R Bael, Izzeddin Bakri, Bashar Jaber, Omar Abu-Zaydeh, Khaled N Al-Shawa
INTRODUCTION AND IMPORTANCE: Chronic Pancreatitis is an irreversible inflammation of the pancreas that can lead to fibrosis and scar formation. Pseudocysts are a late complication of chronic pancreatitis and abdominal pain is the most common presenting complaint. CASE PRESENTATION: A 48-year-old male who is a known case of chronic pancreatitis presented to our department complaining of abdominal pain for a duration of three weeks. A CT scan revealed a pseudocyst in the head of the pancreas, stones in the unicate process along with dilatation of the body and tail of the pancreas...
January 20, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38262462/endoscopic-management-of-hepaticojejunal-anastomosis-fistula-after-whipple-s-resection
#33
Oleg Dovbenko, Oleg Herasymenko
No abstract text is available yet for this article.
December 2024: Endoscopy
https://read.qxmd.com/read/38249287/albumin-bilirubin-albi-score-and-systemic-immune-inflammation-indexes-used-as-pretreatment-outcome-predictors-in-patients-with-pancreatic-ductal-adenocarcinoma-undergoing-robotic-or-open-whipple-procedures-a-logistic-regression-analysis
#34
JOURNAL ARTICLE
Alejandro Mejia, Elaina Vivian, Jimmy Shah, Juan Carlos Barrera Gutierrez
Background Pancreatic ductal adenocarcinoma (PDAC) is the most common type of pancreatic cancer (PC) in the United States. In patients with resectable PC, identification of pretreatment biomarkers before surgery can help in the decision-making process by weighing the benefits of neo-adjuvant therapy, surgical procedure, and adjuvant therapy. The purpose of this study was to determine if the albumin-bilirubin (ALBI) score and immune-inflammatory marker levels can be used in combination as pretreatment predictors of mortality risk in patients undergoing the Whipple procedure (alternatively, pancreatoduodenectomy (PD)) for PDAC...
December 2023: Curēus
https://read.qxmd.com/read/38248019/patient-radiation-exposure-during-enteroscopy-assisted-endoscopic-retrograde-cholangiopancreatography-in-surgically-altered-anatomy-with-video
#35
JOURNAL ARTICLE
Laurent Monino, Tom G Moreels
BACKGROUND: Fluoroscopy must be used cautiously during endoscopic retrograde cholangiopancreatography (ERCP). Radiation exposure data in patients with surgically altered anatomy undergoing enteroscopy-assisted ERCP (EA-ERCP) are scarce. METHODS: 34 consecutive EA-ERCP procedures were compared with 68 conventional ERCP (C-ERCP) procedures. Patient and procedure characteristics and radiation data were collected. RESULTS: Surgical reconstructions were gastrojejunostomy, Roux-en-Y hepaticojejunostomy, Roux-en-Y total gastrectomy, Roux-en-Y gastric bypass and Whipple's duodenopancreatectomy...
January 8, 2024: Diagnostics
https://read.qxmd.com/read/38245948/solid-pseudopapillary-neoplasm-of-the-pancreas-a-case-report-with-a-brief-literature-review
#36
Yasser ALGhabra, Mohammad Hamdi, Malath Alhomsi, Ahmad Alusef, Safaa Qatleesh, Mhd Ali Ousta
INTRODUCTION: Solid pseudopapillary neoplasm (SPN) of the pancreas, representing only 1 % of pancreatic cancers, was identified by Virginia Frantz in 1959. Predominantly affecting young females, it often remains asymptomatic, posing diagnostic challenges due to slow growth. This paper emphasizes SPN's rarity and associated diagnostic complexities. CASE PRESENTATION: In a specific case, a 17-year-old female with post-traumatic right flank pain underwent an enhanced CT scan, revealing a well-defined, hypodense mass in the pancreatic head...
January 10, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38213109/postoperative-fluid-therapy-in-enhanced-recovery-after-surgery-for-pancreaticoduodenectomy
#37
JOURNAL ARTICLE
Sharnice Koek, Johnny Lo, Rupert Ledger, Mohammed Ballal
BACKGROUNDS/AIMS: Optimal intravenous fluid management during the perioperative period for patients undergoing pancreaticoduodenectomy (PD) within the framework of enhanced recovery after surgery (ERAS) is unclear. Studies have indicated that excessive total body salt and water can contribute to the development of oedema, leading to increased morbidity and extended hospital stays. This study aimed to assess the effects of an intravenous therapy regimen during postoperative day (POD) 0 to 2 in PD patients within ERAS...
January 12, 2024: Annals of Hepato-Biliary-Pancreatic Surgery
https://read.qxmd.com/read/38184460/the-double-fired-gastro-jejunostomy-as-a-form-of-improved-efficiency-during-whipple-procedure
#38
JOURNAL ARTICLE
G Fiorentini, A Zironda, A Fogliati, S Warner, S Cleary, R Smoot, M Truty, M Kendrick, D Nagorney, C Thiels, P Starlinger
BACKGROUND: Gastro-jejunostomy (GJ) after pylorus-resecting pancreatoduodenectomy (PD) is most commonly performed in a hand-sewn fashion. Intestinal stapled anastomosis are reported to be as effective as hand-sewn in terms of patency and risk of leakage in other indications. However, the use of a stapled gastro-jejunostomy hasn't been fully assessed in PD. The aim of the present technical report is to evaluate functional outcomes of stapled GJ during PD, its associated effect on operative time and related complications...
December 13, 2023: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://read.qxmd.com/read/38172885/prevalence-estimation-of-tropheryma-whipplei-in-duodenal-biopsy-tissues-of-koreans
#39
JOURNAL ARTICLE
Sumi Yoon, Min Eui Hong, Soon Auck Hong, Tae-Hyoung Kim, Mi-Kyung Lee
Whipple's disease caused by Tropheryma whipplei is difficult to diagnose because of a broad spectrum of manifestations and non-specific clinical signs. In the current global era, the incidence of duodenal infection/inflammation caused by T. whipplei in Korea may has been underestimated. Here we estimated the prevalence of T. whipplei in duodenal biopsy tissues of Koreans using real-time PCRs (RT-PCRs). A total of 252 duodenal biopsy tissues were collected from Korean patients who underwent esophagogastroduodenoscopy and duodenal biopsy...
January 3, 2024: Annals of Clinical Microbiology and Antimicrobials
https://read.qxmd.com/read/38150739/case-report-gastrointestinal-basidiobolomycosis-in-a-young-girl-with-cystic-fibrosis-and-celiac-disease
#40
Ali Tadayon, Omid Reza Azh, Mostafa Poor Khosravani, Seyedeh Sedigheh Hamzavi, Fatemeh Yarmahmoodi, Babak Shirazi Yeganeh, Mehdi Ghasemian
Basidiobolomycosis is an uncommon fungal infection that has been reported in the literature mainly as a cause of infection in the skin and subcutaneous tissue. Intraabdominal infections have been reported in tropical and subtropical areas in the Middle East, such as Iran and Saudi Arabia, and in the United States. Our patient was a 6-year-old girl with cystic fibrosis and celiac disease who was referred to our department with a history of chronic abdominal pain. In the imaging studies of the abdomen and pelvis, a large retroperitoneal mass was reported in the right upper part of the abdomen with involvement of the duodenum and the mesentery of the small and large intestines, as well as the superior mesenteric vessels, and was diagnosed as basidiobolomycosis through biopsy...
December 26, 2023: American Journal of Tropical Medicine and Hygiene
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