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Emotional Damages

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https://www.readbyqxmd.com/read/28769007/the-deletion-of-gpr40-ffar1-signaling-damages-maternal-care-and-emotional-function-in-female-mice
#1
Fuka Aizawa, Yoshihiro Ogaki, Natsuki Kyoya, Takashi Nishinaka, Kazuo Nakamoto, Takashi Kurihara, Akira Hirasawa, Atsuro Miyata, Shogo Tokuyama
The free fatty acid receptor 1 (GPR40/FFAR1) is activated by polyunsaturated fatty acids (PUFAs) such as docosahexaenoic acids (DHA). This receptor has been the focus of many studies regarding physiological functions of the central nervous system. PUFAs are essential for neuronal development and maintenance of neuronal function; thus, the decrease of PUFAs in the brain is closely related to the induction of psychiatric diseases associated with emotional disorder, such as anxiety, depression, and schizophrenia...
2017: Biological & Pharmaceutical Bulletin
https://www.readbyqxmd.com/read/28759598/nurse-in-limbo-a-qualitative-study-of-nursing-in-disasters-in-iranian-context
#2
Negar Pourvakhshoori, Kian Norouzi, Fazlollah Ahmadi, Mohammadali Hosseini, Hamidreza Khankeh
BACKGROUND: An understanding of nurses' experiences in disasters can help to identify their problems in this area. These can be overcome with better planning and preparation. The aim of this study was to explore the experiences and perceptions of disaster nurses regarding their provision of disaster health care services. METHODS: This was a qualitative study using an inductive qualitative content analysis. Participants included 15 Iranian nurses who had experiences of health care delivery in disasters...
2017: PloS One
https://www.readbyqxmd.com/read/28731873/health-related-quality-of-life-in-iranian-adult-men-with-severe-hemophilia
#3
Mohammad Faranoush, Ehsan Shahverdi, Raheb Qorbani, Mostafa Moghaddam
: Health-related quality of life (HRQOL) assessment should be part of the regular clinical assessment of persons with hemophilia. This study assessed quality of life of severe hemophilia patients (Type A) in Tehran comprehensive hemophilia care center. This cross-sectional study was done in 2016 and 84 men aged over 20 years with severe hemophilia (Type A) were assessed. All patients have been treated over 10 years at the comprehensive hemophilia care center, Iran. The HRQOL assessment includes the A36 Hemophilia-QOL questionnaire, sociodemographical and clinical characteristics...
July 20, 2017: Blood Coagulation & Fibrinolysis: An International Journal in Haemostasis and Thrombosis
https://www.readbyqxmd.com/read/28728507/disease-specific-quality-of-life-in-patients-with-lupus-nephritis
#4
M Jolly, S Toloza, B Goker, A E Clarke, S V Navarra, D Wallace, M Weisman, C C Mok
Background Patient-reported outcomes in lupus nephritis (LN) are not well studied. Studies with disease-targeted PRO tool in LN do not exist. Herein, we describe quality of life (QOL: HRQOL & non-HRQOL) among LN patients using LupusPRO. Methods International, cross-sectional data from 1259 patients with systemic lupus erythematosus (SLE) and LupusPRO were compared, stratified by (a) presence of LN (ACR classification criteria (ACR-LN)) at any time and, (b) active LN (on SLEDAI) at study visit. Damage was assessed by SLICC/ACR-SDI...
January 1, 2017: Lupus
https://www.readbyqxmd.com/read/28725865/the-science-of-empathy
#5
Helen Riess
Empathy plays a critical interpersonal and societal role, enabling sharing of experiences, needs, and desires between individuals and providing an emotional bridge that promotes pro-social behavior. This capacity requires an exquisite interplay of neural networks and enables us to perceive the emotions of others, resonate with them emotionally and cognitively, to take in the perspective of others, and to distinguish between our own and others' emotions. Studies show empathy declines during medical training...
June 2017: Journal of patient experience
https://www.readbyqxmd.com/read/28723344/social-cognition-impairments-after-aneurysmal-subarachnoid-haemorrhage-associations-with-deficits-in-interpersonal-behaviour-apathy-and-impaired-self-awareness
#6
Anne M Buunk, Jacoba M Spikman, Wencke S Veenstra, Peter Jan van Laar, Jan D M Metzemaekers, J Marc C van Dijk, Linda C Meiners, Rob J M Groen
Behavioural disturbances are frequently found after aneurysmal subarachnoid haemorrhage (aSAH). Social cognition impairments have been suggested as a possible underlying mechanism for behavioural problems. Also, aSAH is likely to result in damage affecting frontal-subcortical circuits underlying social cognition. Therefore, we aimed to investigate social cognition after aSAH and its associations with behavioural problems (deficits in interpersonal behaviour, apathy, and impaired self-awareness) and focal as well as diffuse brain damage...
July 16, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28712330/the-role-of-abnormalities-in-the-corpus-callosum-in-social-cognition-deficits-after-traumatic-brain-injury
#7
Skye McDonald, Jacqueline A Rushby, Katie I Dalton, Samantha K Allen, Nicklas Parks
The corpus callosum (CC) is vulnerable to severe traumatic brain injury (TBI). Social cognition requires integration of non-verbal and verbal information in order to understand social behaviour and may be compromised if the CC is damaged. 17 adults with severe, chronic TBI and 17 control participants underwent structural MRI and Diffusion Tensor Imaging. A region of interest analysis examined fractional anisotropy (FA) and mean diffusivity (MD) across regions of the CC. Performance on The Awareness of Social Inference Test (TASIT): part 1 (emotion recognition) and parts 2 and 3 (social inference), was examined in relation to FA and MD...
July 17, 2017: Social Neuroscience
https://www.readbyqxmd.com/read/28708033/neuropsychological-profile-and-social-cognition-in-congenital-central-hypoventilation-syndrome-cchs-correlation-with-neuroimaging-in-a-clinical-case
#8
Borja Esteso Orduña, Raquel Seijas Gómez, Elena García Esparza, Emily M Briceño, Javier Melero Llorente, María de la Concepción Fournier Del Castillo
INTRODUCTION: Congenital central hypoventilation syndrome (CCHS) is a rare genetic disorder due to paired-like homeobox gene (PHOX2B) mutations. CCHS patients suffer from dysregulation of the autonomic nervous system characterized by the absence of or extremely reduced response to hypercapnia and hypoxia, with neuropsychological deficits. The aim of this exploratory study is to describe the longitudinal neuropsychological profile and its correlations with magnetic resonance imaging (MRI) of a child with CCHS with a PHOX2B mutation...
July 14, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28706551/informal-caregivers-experiences-of-caring-of-multiple-sclerosis-patients-a-qualitative-study
#9
Somayeh Gafari, Masoud F Khoshknab, Kian Nourozi, Eesa Mohamadi
BACKGROUND: Approximately one-third of people suffering from multiple sclerosis (MS) need long-term care by their families, however, we know little of their experiences. Exploring these experiences can be a guideline to improve the quality of care for MS patients. The goal of this study is to explore informal caregivers' experiences regarding care of MS patients. MATERIALS AND METHODS: A qualitative content analysis method was used to conduct this study in 2014...
May 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28702721/peptides-semax-and-selank-affect-the-behavior-of-rats-with-6-ohda-induced-pd-like-parkinsonism
#10
P A Slominsky, M I Shadrina, T A Kolomin, A V Stavrovskaya, E V Filatova, L A Andreeva, S N Illarioshkin, N F Myasoedov
Parkinson's disease (PD) is the second most common severe neurodegenerative disorder that is characterized by progressive degeneration of dopaminergic neurons (DA neurons) in the substantia nigra pars compacta (SNpc) region of the brain. In the present study, we investigated the effects of the synthetic regulatory peptides Semax (analog of an ACTH 4-10 fragment (ACTH4-10)) and Selank (analog of immunomodulatory taftsin) on behavior of rats with 6-hydroxidopamine (6-OHDA) induced PD-like parkinsonism. It was showed that both peptides did not affect motor activity of rats in elevated cross shaped maze and passive defensive behavior of the animals...
May 2017: Doklady Biological Sciences: Proceedings of the Academy of Sciences of the USSR, Biological Sciences Sections
https://www.readbyqxmd.com/read/28700143/consequences-of-brain-tumour-resection-on-emotion-recognition
#11
Giulia Mattavelli, Alberto Pisoni, Alessandra Casarotti, Alessandro Comi, Giada Sera, Marco Riva, Alberto Bizzi, Marco Rossi, Lorenzo Bello, Costanza Papagno
Emotion processing impairments are common in patients undergoing brain surgery for fronto-temporal tumour resection, with potential consequences on social interactions. However, evidence is controversial concerning side and site of lesions causing such deficits. This study investigates visual and auditory emotion recognition in brain tumour patients with the aim of clarifying which lesion sites are related to impairments in emotion processing from different modalities. Thirty-four patients were evaluated, before and after surgery, on facial expression and emotional prosody recognition; voxel-based lesion-symptom mapping (VLSM) analyses were performed on patients' post-surgery MRI images...
July 12, 2017: Journal of Neuropsychology
https://www.readbyqxmd.com/read/28692433/a-nursing-pain-assessment-and-record-information-system-design-and-application-in-the-oncology-department
#12
Pan-Feng Wang, Li-Qiong Shen, Hong-Jun Zhang, Bao-Hua Li, Hong Ji
Pain is an unpleasant sensory and emotional feeling accompanying existing, impending, or potential tissue damage. Valid pain assessment and standardized pain documentation are important in oncology pain management; however, they are still deficient. Thus, we developed a pain assessment and record information system for nurses in the oncology department and implemented a questionnaire survey to evaluate users' acceptance of the system. The pain assessment system focused on usability and efficiency to provide a modified workflow that was safe, less time-consuming, patient centered, enjoyable, and efficient...
July 7, 2017: Computers, Informatics, Nursing: CIN
https://www.readbyqxmd.com/read/28681915/17%C3%AE-estradiol-rescues-damages-following-traumatic-brain-injury-from-molecule-to-behavior-in-mice
#13
Huaihai Lu, Kun Ma, Liwei Jin, He Zhu, Ruiqi Cao
Traumatic brain injury (TBI) is a public health concern, and causes cognitive dysfunction, emotional disorders, and neurodegeration, as well. The currently available treatments are all symptom-oriented with unsatifying efficacy. It is highly demanded to understand its underlying mechanisms. Controlled cortical impact (CCI) was used to induce TBI in aged female mice subjected to ovariectomy. Brain damages were assessed with neurological severity score, brain infarction and edema. Morris water maze and elevated plus maze were applied to evaluate the levels of anxiety...
July 6, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28681486/ultrastructural-alterations-of-von-economo-neurons-in-the-anterior-cingulate-cortex-in-schizophrenia
#14
Martin Krause, Carsten Theiss, Martin Brüne
Von Economo neurons (VEN) are large bipolar projection neurons mainly located in layer Vb of anterior cingulate cortex (ACC) and anterior insula. Both regions are involved in cognitive and emotional procedures and are functionally and anatomically altered in schizophrenia. Although the detailed function of VEN remains unclear, it has been suggested that these neurons are involved in the pathomechanism of schizophrenia. Here, we were interested in the question whether or not the VEN of schizophrenia patients would show abnormalities at the ultrastructural level...
July 6, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28678317/analysis-of-psychological-characteristics-of-obese-children
#15
L-F Liu, Q-T Bian, J-G Zhai
OBJECTIVE: We conducted this study to analyze the psychological characteristics of obese children. PATIENTS AND METHODS: We selected 60 cases of obese children as obesity group and according to 1:1 matching principle, we selected 60 normal weight children as the control group. We investigated and analyzed children's family behavior, mental health, temperament, self-consciousness and social adaptability. RESULTS: The proportion of children with adverse behavior in the obesity group was significantly higher than that in the control group (p < 0...
June 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28660160/the-2017-academic-college-of-emergency-experts-and-academy-of-family-physicians-of-india-position-statement-on-preventing-violence-against-health-care-workers-and-vandalization-of-health-care-facilities-in-india
#16
Vivek Chauhan, Sagar Galwankar, Raman Kumar, Sunil Kumar Raina, Praveen Aggarwal, Naman Agrawal, S Vimal Krishnan, Sanjeev Bhoi, O P Kalra, Santosh T Soans, Vandana Aggarwal, Mohan Kubendra, R Bijayraj, Sumana Datta, R P Srivastava
There have been multiple incidents where doctors have been assaulted by patient relatives and hospital facilities have been vandalized. This has led to mass agitations by Physicians across India. Violence and vandalism against health-care workers (HCWs) is one of the biggest public health and patient care challenge in India. The sheer intensity of emotional hijack and the stress levels in both practicing HCWs and patient relative's needs immediate and detail attention. The suffering of HCWs who are hurt, the damage to hospital facilities and the reactionary agitation which affects patients who need care are all together doing everything to damage the delivery of health care and relationship between a doctor and a patient...
April 2017: International Journal of Critical Illness and Injury Science
https://www.readbyqxmd.com/read/28649203/trps-in-pain-sensation
#17
REVIEW
Isaac Jardín, José J López, Raquel Diez, José Sánchez-Collado, Carlos Cantonero, Letizia Albarrán, Geoffrey E Woodard, Pedro C Redondo, Ginés M Salido, Tarik Smani, Juan A Rosado
According to the International Association for the Study of Pain (IASP) pain is characterized as an "unpleasant sensory and emotional experience associated with actual or potential tissue damage". The TRP super-family, compressing up to 28 isoforms in mammals, mediates a myriad of physiological and pathophysiological processes, pain among them. TRP channel might be constituted by similar or different TRP subunits, which will result in the formation of homomeric or heteromeric channels with distinct properties and functions...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28626799/acute-ischemic-lesions-associated-with-impairments-in-expression-and-recognition-of-affective-prosody
#18
Amy E Wright, Cameron Davis, Yessenia Gomez, Joseph Posner, Christopher Rorden, Argye E Hillis, Donna C Tippett
PURPOSE: We aimed to: (a) review existing data on the neural basis of affective prosody;(b) test the hypothesis that there are double dissociations in impairments of expression and recognition of affective prosody; and (c) identify areas of infarct associated with impaired expression and/or recognition of affective prosody after acute right hemisphere (RH) ischemic stroke. METHODS: Participants were tested on recognition of emotional prosody in content-neutral sentences...
July 2016: Perspectives of the ASHA special interest groups
https://www.readbyqxmd.com/read/28616394/new-method-of-sudomotor-function-measurement-to-detect-microvascular-disease-and-sweat-gland-nerve-or-unmyelinated-c-fiber-dysfunction-in-adults-with-retinopathy
#19
John E Lewis, Steven E Atlas, Ammar Rasul, Ashar Farooqi, Laura Lantigua, Oscar L Higuera, Andrea Fiallo, Lianette Laria, Renata Picciani, Ken Wals, Zohar Yehoshua, Armando Mendez, Janet Konefal, Sharon Goldberg, Judi Woolger
BACKGROUND: Diabetes-associated microvascular complications such as retinopathy and neuropathy often lead to end-organ and tissue damage. Impaired skin microcirculation often precedes the detection of other advanced diabetic complications. The ANS-1 system contains a redesigned sympathetic skin response (ANS-1 SSR) device that measures sudomotor function, a photoplethysmography sensor, and a blood pressure device to comprehensively assess cardiac autonomic neuropathy and endothelial dysfunction...
2017: Journal of Diabetes and Metabolic Disorders
https://www.readbyqxmd.com/read/28614919/-effects-of-developmental-exposure-to-dehp-on-learning-and-memory-of-mice
#20
D J Wu, B B Luo, Q W Feng, Q N Wang
Objective: To investigate the effects of developmental exposure to DEHP on learning and memory of mice. Methods: Male littermates of ICR mice randomly assigned to five experimental groups (n=14 for each condition) on PND4 to receive distilled water, vehicle and 10, 50 and 200 mg/ (kg·d) DEHP from PND5 to PND38 by gavage, weighing and recording body weight of mice. Open field task were conducted on PND 26 and Morris water maze task were begun from PND30 to PND 37 to evaluate spontaneous exploration activity and emotion, spatial learning and memory performance of pubertal mice, respectively...
April 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
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