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JOURNAL ARTICLE
M Calvani, S D'Iddio, A de Gaetano, P Mariotti, L Mosconi, M G Pomponi, E Tabolacci, M G Torrioli, S Vernacotola, G Neri
Hyperactivity is a significant problem for almost all young males affected by fragile X syndrome (FXS), the most common inherited disease causing mental retardation. Therapeutical approaches are actually based on Central Nervous System (CNS) stimulants lacking a well defined rationale and efficacy while they further decrease the patient's limited attention span. A pilot study on 17 fragile X male treated with L-acetylcarnitine (LAC) over one year, showed a significant reduction of their hyperactivity behaviour tested by the Conners Abbreviated Parent-Teacher Questionnaire...
October 2001: Revista de Neurologia
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