Anabela Malho Guedes, Roberto Calças Marques, Ana Teresa Domingos, Céu Laranjo, Ana Paula Silva, Anabela Rodrigues, Raymond T Krediet
Longitudinal evolution of peritoneal protein loss (PPL), a reflection of hydrostatic pressure-driven leak of plasma proteins through the large-pore pathway, is not clear. Time on PD causes loss of mesothelial cells, vasculopathy, and increased thickness of the submesothelial fibrous layer. Are these structural changes associated with progressive increase of PPL, in a parallel with the rise in the D/P creatinine? The aim of the present study was to identify longitudinal changes of PPL over time. This single-center, longitudinal study included 52 peritoneal dialysis (PD) patients with a median follow-up of 26...
February 29, 2024: Seminars in Dialysis