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African surgery

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https://www.readbyqxmd.com/read/29154023/triple-negative-breast-cancer-in-asia-an-insider-s-view
#1
REVIEW
Chao Wang, Shreya Kar, Xianning Lai, Wanpei Cai, Frank Arfuso, Gautam Sethi, Peter E Lobie, Boon C Goh, Lina H K Lim, Mikael Hartman, Ching W Chan, Soo C Lee, Sing H Tan, Alan P Kumar
While tremendous improvement has been made for the treatment of breast cancers, the treatment of triple negative breast cancer (TNBC) still remains a challenge due to its aggressive characteristics and limited treatment options. Most of the studies on TNBC were conducted in Western population and TNBC is reported to be more frequent in the African women. This review encapsulates the studies conducted on TNBC patients in Asian population and elucidates the similarities and differences between these two regions...
November 10, 2017: Cancer Treatment Reviews
https://www.readbyqxmd.com/read/29152519/primary-carcinosarcoma-of-the-pancreas-with-cd10-positive-sarcoma-component
#2
Christine J Salibay, Julia Rewerska, Shweta Gupta, Nicholas Ree
Carcinosarcomas of the pancreas are rare entities with a dismal prognosis. We report a rare case of pancreatic carcinosarcoma in a 49-year-old African American female who underwent a total abdominal hysterectomy with right salpingo-oophorectomy and exploration of the pancreatic mass. The surgery revealed a sclerotic mass in the body and tail of the pancreas that was surgically unresectable, and a pancreatic biopsy confirmed the pathology of pancreatic carcinosarcoma. Histologically, the lesion showed a high-grade spindle cell sarcoma and adjacent moderately differentiated adenocarcinoma...
October 2017: Journal of Investigative Medicine High Impact Case Reports
https://www.readbyqxmd.com/read/29138366/lower-repeat-revascularization-rates-among-patients-with-prior-coronary-artery-bypass-graft-surgery-are-due-to-lack-of-adequate-target-vessels
#3
Anirudh Kumar, John F Wagener, Daniel Wojdyla, W Schuyler Jones, Manesh R Patel, Sunil V Rao
BACKGROUND: Studies comparing percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) surgery in patients with multivessel coronary artery disease (CAD) have shown lower repeat revascularization rates in patients who undergo CABG. The reason remains unclear. METHODS: We identified patients with multivessel CAD who received CABG or PCI enrolled in the Duke Databank for Cardiovascular Disease (2003 to 2012). We compared the incidence of major adverse cardiovascular and cerebrovascular events (MACCE) between the two groups...
November 15, 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29131502/racial-identity-aesthetic-surgery-and-yor%C3%A3-b%C3%A3-african-values
#4
Ademola K Fayemi
The question of racial identity in the process and outcome of aesthetic surgery is gaining increasing attention in bioethical discourse. This paper attempts an ethical examination of the racial identity issues involved in aesthetic surgery. Dominant moral values in Western culture are explored in the evaluation of aesthetic surgery. The paper argues that African values are yet to receive the universal attention they arguably deserve especially in the rethinking of values underlying aesthetic surgery as racial transformation...
November 12, 2017: Developing World Bioethics
https://www.readbyqxmd.com/read/29130482/longitudinal-observational-study-of-hidradenitis-suppurativa-impact-of-surgical-intervention-with-adjunctive-biologic-therapy
#5
Victoria K Shanmugam, Shaunak Mulani, Sean McNish, Sarah Harris, Teresa Buescher, Richard Amdur
BACKGROUND: Hidradenitis supppurativa (HS) is a chronic inflammatory disease of the apocrine sweat glands affecting 1-4% of the population. While surgical excision is a mainstay of therapy, lesions often recur. Biologic therapies, including tumor necrosis factor-α and IL-12/23 inhibitors, are effective for mild to moderate HS. However, longitudinal studies investigating biologic therapy in conjunction with surgery are limited. The purpose of this analysis was to investigate impact of surgery and biologic therapy on HS disease activity...
November 11, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/29129978/a-case-of-peripheral-ulcerative-keratitis-associated-with-autoimmune-hepatitis
#6
Hamoon Eshraghi, Aria Mahtabfar, Mohammad H Dastjerdi
Purpose: To describe a case of peripheral ulcerative keratitis in the setting of autoimmune hepatitis and possible overlap syndrome with primary sclerosing cholangitis. Case Report: A 48-year-old African American female with autoimmune hepatitis with possible overlap syndrome with primary sclerosing cholangitis presented with tearing, irritation, and injection of the left eye that was determined to be peripheral ulcerative keratitis. The patient was treated with topical and systemic steroids, immunosuppressant drugs (azathioprine and mycophenolate mofetil), a biologic (rituximab), and surgery (conjunctival resection), and the peripheral ulcerative keratitis epithelialized but ultimately led to corneal perforation...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/29128105/factors-associated-with-delivery-of-neoadjuvant-chemotherapy-in-women-with-advanced-stage-ovarian-cancer
#7
Emily Hinchcliff, Alexander Melamed, Amy Bregar, Elisabeth Diver, Joel Clemmer, Marcela Del Carmen, John O Schorge, J Alejandro Rauh-Hain
PURPOSE: To identify clinical and non-clinical factors associated with utilization of primary cytoreductive surgery (PCS) or neoadjuvant chemotherapy (NACT) in women with advanced stage epithelial ovarian cancer (EOC). METHODS: Using the National Cancer Database, we identified women with stage IIIC and IV EOC diagnosed from 2012 to 2014. The primary outcome was receipt of NACT, defined in the primary analysis as utilization of chemotherapy as the first cancer-directed therapy, irrespective of whether interval surgery was performed...
November 8, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29119221/preparing-japanese-surgeons-for-potential-mass-casualty-situations-will-require-innovative-and-systematic-programs
#8
H Uchino, V Y Kong, J L Bruce, G V Oosthuizen, W Bekker, G L Laing, D L Clarke
INTRODUCTION: The ongoing state of global geo-political instability means that it is prudent to prepare civilian surgeons to manage major military-type trauma. Japan has enjoyed a prolonged period of peace and consequently it is unlikely that surgeons will have been exposed to a sufficient volume of cases. This study reviews the state of trauma training and preparedness in Japan and reviews the trauma workload of a major Japanese emergency medical center and compared with a major South African trauma center with the intention of quantifying and comparing the time needed to gain adequate exposure to major trauma at the two centers...
November 8, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29118232/healthcare-utilization-and-costs-during-the-initial-phase-of-care-among-elderly-women-with-breast-cancer
#9
Ami Vyas, S Suresh Madhavan, Usha Sambamoorthi, Xiaoyun Lucy Pan, Michael Regier, Hannah Hazard, Sita Kalidindi
Background: Understanding the patterns of healthcare utilization and costs during the initial phase of care (12 months after breast cancer [BC] diagnosis) in older women (aged ≥65 years) is crucial in the allocation of Medicare resources. The objective of this study was to determine healthcare utilization and costs during the initial phase of care in older, female, Medicare fee-for-service beneficiaries diagnosed with BC, and to determine the factors associated with higher costs. Methods: A retrospective observational study using the SEER-Medicare linked database was conducted in 69,307 women aged ≥66 years diagnosed with primary incident BC in 2003-2009 to determine healthcare utilization, average costs, and costs for specific services during the initial phase of care...
November 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/29111084/a-model-for-humanitarian-outreach-in-today-s-world
#10
REVIEW
James A O'Neill
The traditional model for humanitarian work for surgeons has been a few long-term people and a larger number of volunteers on short-term missions to needy places for one or two weeks with limited opportunity for follow-up. While a great deal of good has resulted from these efforts, in the long term not much has changed. Recent studies like the U.N. Millennium Development Goals and the Lancet Commission Report, Surgery 2030, have pointed out that the burden of surgical disease is the major public health issue in the world, such that an estimated five billion people worldwide do not have access to safe surgery and anesthesia, with the largest number being in Africa where almost half of the population is less than age 18years...
October 10, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29103849/the-effect-of-skin-pigmentation-on-determination-of-limb-ischemia
#11
Elizabeth M Polfer, Ryan M Zimmerman, Eshetu Tefera, Ryan D Katz, James P Higgins, Kenneth R Means
PURPOSE: Timely identification of tissue ischemia is critical, both in the traumatized limb and following free tissue transfer. The purpose of this study was to determine if skin pigmentation affects the ability to detect limb ischemia. METHODS: We conducted a study of healthy controls exposed to limb ischemia. The subjects were classified based on skin pigmentation using a defined skin type assessment tool, a visual color scale, and self-description of race. Participants were randomized by limb and tourniquet status; surgeons were blinded to both...
November 2, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/29103529/influence-of-race-insurance-status-and-geographic-access-to-plastic-surgeons-on-immediate-breast-reconstruction-rates
#12
Paris D Butler, Olatomide Familusi, Joseph M Serletti, Justin P Fox
BACKGROUND: This study evaluates the rates of immediate breast reconstruction (IBR) among racial and insurance status subgroups, in the setting of a changing plastic surgeon workforce. METHODS: Using state level inpatient and ambulatory surgery data, we identified discharges for adult women who underwent mastectomy for breast cancer. This information was supplemented with plastic surgeon workforce data and aggregated to the health service area-level (HSA). Hierarchical linear models were used to risk standardized IBR rates for 8 race-payer subgroups...
November 2, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29101926/scrotal-calcinosis-two-case-reports
#13
O Karray, A Dhaoui, R Boulma, K Bellil, H Khouni
BACKGROUND: Scrotal calcinosis is a rare and benign condition. It usually gives rise to few symptoms, and the impact is mainly functional and aesthetic. It is considered part of dystrophic calcinosis cutis. Surgical management is the only curative approach, and recurrence has been described in few cases. CASE PRESENTATION: We report cases of two North African white patients with operated scrotal calcinosis. We describe the clinical and histological aspects as well as a pathogenic hypothesis and surgical management principles...
November 5, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29081801/level-of-concordance-of-pre-intra-and-postoperative-staging-in-cervical-cancers-treya-study
#14
M Toure, A T Bambara, K K Y Kouassi, E N Seka, J M Dia, I Yao, O Kimso, I Adoubi
Concomitant radiochemotherapy is the therapeutic standard for locally advanced (Ib2 to IVa stage FIGO) cervical cancer. In the absence of a radiotherapy in many of our Sub-Saharan African countries, surgical resection is the only therapeutic method available in hopes of achieving a definite cure. However, criteria for curative surgery are not always met due to preoperative understaging of most of our patients. In addition to socioeconomic factors, the causes for understaging are numerous. These include the lack of personnel or underqualified personnel and the absence of complete workup to assess the resectability of the tumor, but above all the lack of decision-making through multidisciplinary consultation meetings...
2017: Journal of Oncology
https://www.readbyqxmd.com/read/29079381/bariatric-surgery-in-hiv-patients-experience-of-an-obesity-reference-center-in-france
#15
Guillaume Pourcher, Gilles Peytavin, Luminita Schneider, Sébastien Gallien, Gilles Force, Valérie Pourcher
BACKGROUND: Few data on bariatric surgery are available regarding obese human immunodeficiency virus (HIV)-infected patients. SETTINGS: Antoine Beclere hospital, Clamart, Paris-sud University, France METHODS: Prospective observational follow-up study recruited HIV-infected patients who underwent bariatric surgery from 2009 to 2015. Baseline demographic characteristics, surgery characteristics, perioperative outcomes, changes in weight loss, HIV markers, antiretroviral drug plasma levels are described...
September 14, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/29066492/granulomatous-thyroiditis-a-case-report-and-literature-review
#16
Darshan P Trivedi, Ramesh Bhagat, Yukihiro Nakanishi, Alun Wang, Krzysztof Moroz, Nadja K Falk
BACKGROUND: Granulomatous disease in the thyroid gland has been linked to viral, bacterial and autoimmune etiologies. The most common granulomatous disease of the thyroid is subacute granulomatous thyroiditis, which is presumed to have a viral or post-viral inflammatory cause. Bacterial etiologies include tuberculosis, actinomycosis, and nocardiosis, but are extremely rare. Disseminated actinomycosis and nocardiosis more commonly affect organ-transplant patients with the highest susceptibility within the first year after transplant surgery...
September 2017: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/29064879/the-successful-implementation-of-a-modified-enhanced-recovery-after-surgery-eras-program-for-bariatric-surgery-in-a-south-african-teaching-hospital
#17
Emil Loots, Benn Sartorius, Imran M Paruk, Damian L Clarke
BACKGROUND: This study assessed the impact of strict adherence to perioperative pathways incorporating an enhanced recovery after surgery protocol on the outcomes of bariatric surgery at our center. METHODS: Prospective data were collected on 62 patients undergoing bariatric surgery between January 2011 and March 2016. Outcomes were compared between those who adhered to the perioperative pathway and those who did not. RESULTS: Fifty-three patients underwent laparoscopic sleeve gastrectomy, and 9 patients underwent Laparoscopic Roux-en-Y Gastric Bypass...
October 23, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/29060195/assessment-of-3d-morphological-characteristics-of-the-shoulder-bones-using-statistical-shape-modeling-prospective-application-to-handedness
#18
Adijat O Inyang, Jean-Rassaire Fouefack, Sudesh Sivarasu, Stephen Roche, Bhushan Borotikar, Valerie Burdin, Tinashe Mutsvangwa
In this study we have described the use of statistical shape modeling (SSM) technique in evaluating the morphological variation of shoulder bones from a South African population. The anatomical landmark selections were carried out, followed by the registration of the meshes which were validated before establishing the dense correspondence. The SSMs were built and average shape comparison from each side for each bone were made in order to evaluate handedness. In general, there was no error found around the gleno-humeral region which may suggest that the usage of contralateral healthy shoulder could serve as an informed decision making tool for surgery and prosthesis design...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29058627/urethrovaginal-fistula-following-vaginal-prolapse-of-a-pedunculated-uterine-myoma-a-case-report
#19
Elie Nkwabong, Joseph Nelson Fomulu
BACKGROUND: Urethrovaginal fistulas are usually secondary to a foreign body in the vagina or to vaginal gynecologic surgeries. We present a case of an urethrovaginal fistula secondary to vaginal prolapse of a huge pedunculated submucosal uterine myoma. CASE PRESENTATION: A 25-year-old black African woman with a past history of huge uterine fibroids and an uncomplicated vaginal delivery 5 weeks prior to presentation consulted for a difficult micturition that occurred 2 days earlier...
October 21, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29050886/disparities-in-access-to-emergency-general-surgery-care-in-the-united-states
#20
Jasmine A Khubchandani, Connie Shen, Didem Ayturk, Catarina I Kiefe, Heena P Santry
BACKGROUND: As fewer surgeons take emergency general surgery call and hospitals decrease emergency services, a crisis in access looms in the United States. We examined national emergency general surgery capacity and county-level determinants of access to emergency general surgery care with special attention to disparities. METHODS: To identify potential emergency general surgery hospitals, we queried the database of the American Hospital Association for "acute care general hospital," with "surgical services," and "emergency department," and ≥1 "operating room...
October 16, 2017: Surgery
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