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https://www.readbyqxmd.com/read/29145710/testosterone-replacement-in-transgenic-sickle-cell-mice-controls-priapic-activity-and-upregulates-pde5-expression-and-enos-activity-in-the-penis
#1
B Musicki, S Karakus, W Akakpo, F H Silva, J Liu, H Chen, B R Zirkin, A L Burnett
Sickle cell disease (SCD)-associated priapism is characterized by decreased nitric oxide (NO) signaling and downregulated phosphodiesterase (PDE)5 protein expression and activity in the penis. Priapism is also associated with testosterone deficiency, but molecular mechanisms underlying testosterone effects in the penis in SCD are not known. Given the critical role of androgens in erection physiology and NO synthase (NOS)/PDE5 expression, we hypothesized that testosterone replacement to eugonadal testosterone levels reduces priapism by reversing impaired endothelial (e)NOS activity and molecular abnormalities involving PDE5...
November 16, 2017: Andrology
https://www.readbyqxmd.com/read/29144629/single-perineal-incision-placement-of-artificial-urinary-sphincter-with-cadaveric-correlation-of-sub-dartos-pump-placement
#2
Cooper R Benson, Hajar I Ayoub, O Lenaine Westney
PURPOSE: We present a novel AUS implantation technique using a single perineal incision for single device placement or in combination with an inflatable penile prosthesis (IPP). Urinary and sexual dysfunction following the management of prostate cancer has a significant impact on the quality of life of our patients. While there are marginal changes in the prosthetic devices, we strive to reduce post-operative morbidity while maximizing efficacy. MATERIALS AND METHODS: We retrospectively reviewed the outcomes of 6 patients who underwent single perineal incision placement of a virgin AUS in 2014, 3 with simultaneous IPP placement...
November 19, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29131778/adventures-and-misadventures-in-plastic-surgery-and-soft-tissue-implants
#3
Dana J Lin, Tony T Wong, Gina A Ciavarra, Jonathan K Kazam
Soft-tissue augmentation and implants are increasingly seen by the radiologist as more techniques emerge for a variety of indications and locations. Some surgical and implant procedures are performed for purely cosmetic reasons in otherwise healthy patients seeking to improve their body image, and some are performed for reconstruction after cancer or other chronic illnesses. Abdominoplasty, liposuction, and autologous fat grafting can be performed for abdominal and gluteal contouring. Injection of liquid injectable silicone has historically been fraught with legal issues, although it continues to be used for augmentation in a variety of anatomic locations...
November 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29126283/surgical-management-of-penile-lesions-secondary-to-foreign-body-reaction-a-case-report-and-systematic-review
#4
Pedro L S Faveret, Fábio Santiago
Background: To improve the penile contour, some men choose to undergo implantation or injection of nonbiological materials. Foreign body reactions in penile tissue may produce scarring, deformity, ulceration, necrosis, and even gangrene. Consensus is lacking regarding the most effective surgical procedure for reconstruction of these penile lesions. Objectives: The authors describe one case study and the first systematic review focusing on reconstructive surgical management for penile lesions secondary to foreign body reaction...
November 6, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29124870/defining-a-hba1c-value-that-predicts-increased-risk-of-penile-implant-infection
#5
Mohamad Habous, Raanan Tal, Tarek Soliman, Alaa Tealab, Mohammed Nassar, Zenhom Mekawi, Saad Mahmoud, Osama Abdelwahab, Mohamed Elkhouly, Hatem Kamr, Abdallah Remeah, Saleh Binsaleh, David Ralph, John Mulhall
OBJECTIVES: To explore the association between HbA1C level and penile implant infection rates and to define a cut-off value that predicted implant infection. PATIENTS AND METHODS: A multi center prospective study included all patients undergoing penile implant surgery between 2009-15. Preoperative, perioperative and postoperative management were identical for the entire cohort. Univariate analysis was performed to define predictors of implant infection. HbA1c levels were analyzed as a continuous variable and sequential analysis was conducted utilizing 0...
November 10, 2017: BJU International
https://www.readbyqxmd.com/read/29118538/utilization-of-penile-prosthesis-and-male-incontinence-prosthetics-in-saudi-arabia
#6
Amjad Alwaal, Ahmad J Al-Sayyad
Background: Erectile dysfunction is a prevalent disease affecting over 50% of men between the ages of 40 and 70 years. Penile prosthesis represents the end of the line treatment when other less invasive therapies fail or are contraindicated. Male stress urinary incontinence can significantly diminish quality of life and lead to embarrassment and social withdrawal. Surgical therapies, such as male urethral slings and artificial urinary sphincters (AUS), are considered effective and safe treatments for male stress incontinence...
October 2017: Urology Annals
https://www.readbyqxmd.com/read/29111200/quality-of-life-psychological-functioning-and-treatment-satisfaction-of-men-who-have-undergone-penile-prosthesis-surgery-following-robot-assisted-radical-prostatectomy
#7
Brindha Pillay, Daniel Moon, Christopher Love, Denny Meyer, Emma Ferguson, Helen Crowe, Nicholas Howard, Sarah Mann, Addie Wootten
BACKGROUND: Penile prosthesis surgery is last-line treatment to regaining erectile function after radical prostatectomy (RP) for localized prostate cancer. AIMS: To assess quality of life, psychological functioning, and treatment satisfaction of men who underwent penile implantation after RP; the psychosocial correlates of treatment satisfaction and sexual function after surgery; and the relation between patients' and partners' ratings of treatment satisfaction...
October 27, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29110808/how-big-is-too-big-the-girth-of-bestselling-insertive-sex-toys-to-guide-maximal-neophallus-dimensions
#8
Dylan Isaacson, Roxana Aghili, Non Wongwittavas, Maurice Garcia
BACKGROUND: In our practice we have encountered 4 female-to-male transgender patients seeking neophallus revision surgery for girth precluding penetrative vaginal or anal intercourse. Despite this, there is little evidence available to guide transitioning patients in neophallus sizing. In this work we examined the dimensions of bestselling realistic dildos, presuming that the most popular dimensions would reflect population preferences for penetrative toys and phalluses. AIM: To determine a maximal upper limit for girth compatible with penetrative intercourse based on measurements of bestselling realistic dildos and published erect penile dimensions...
November 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29080947/complications-of-penile-self-injections-investigation-of-680-patients-with-complications-following-penile-self-injections-with-mineral-oil
#9
Johannes Nordsteien Svensøy, Valentine Travers, Palle Jörn Sloth Osther
OBJECTIVE: Penile implants and injection of foreign materials have been described in texts like Kama Sutra for more than 1500 years, and are still being practiced around the world. The extent of this practice is unknown, and the documentation available today only scratches the surface. This study investigates and documents the complications after penile self-injections at the Mae Tao Clinic. To our knowledge, this study represents the largest series of patients representing complications to penile self-injections...
October 28, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29058838/-early-implantation-of-a-penile-prosthesis-as-an-optimal-treatment-of-retractory-low-flow-priapism
#10
M Dormal, R Andrianne, M Sempels, D Waltregny
Low flow priapism is a urologic emergency because it leads to erectile dysfunction due to cavernosal fibrosis. Several treatments exist, including cavernosal aspiration, washing with or without alpha-mimetic agent or shunting surgery. In case of failure of these methods or prolonged priapism (superior to 36 hours), the option of early penile prostheses implantation should be discussed with a motivated patient in order to improve sexual satisfaction.
October 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29052831/klingsor-syndrome-a-rare-surgical-emergency
#11
Gaurav Aggarwal, Samiran D Adhikary
Klingsor syndrome or self-Inflicted traumatic penile amputation is a rare clinical entity that is associated with psychiatric disorders, command hallucinations, religious preoccupations, substance abuse, and isolation from or neglect by society. In addition to being infrequently encountered, it is a rare surgical emergency, with paucity of data on appropriate and timely management to ensure optimal functional outcomes. We report the case of a 25-year-old unmarried male who inflicted this injury upon himself in a fit of paranoia as a way to expiate his sins and earn solace from God...
September 2017: Ulusal Travma Ve Acil Cerrahi Dergisi, Turkish Journal of Trauma & Emergency Surgery: TJTES
https://www.readbyqxmd.com/read/29031427/-penile-prosthesis-implantation-indications-and-outcomes
#12
W Akakpo, K Ben-Naoum, D Carnicelli, L Ferretti, J-P Graziana, V Hupertan, E Huyghe, F X Madec, F Marcelli, C Methorst, N Morel-Journel, L Savareux, J E Terrier, R Yiou, A Faix
OBJECTIVE: Our aim was to present the indications and the outcomes of penile prosthesis implantation. METHODS: A literature review was performed through PubMed using the following keywords: penile implantation ; penile prosthesis; erectile dysfunction. RESULTS: Evolution of penile prosthesis devices led to get a fiable and effective treatment for men with erectile dysfunction who do not respond to less invasive therapy. Penile implant can also be useful in the treatment of Peyronie's disease, priapism and transgender surgery...
October 12, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/29017517/traumatic-penile-amputation-a-case-report
#13
Tushar Patial, Girish Sharma, Pamposh Raina
BACKGROUND: Traumatic amputation of the penis is a rare surgical emergency. Although repair techniques have been well described in literature, failure of replantation and its causes are poorly understood and reported. Herein, we report the case of a 9 year old boy who underwent replantation of his amputated penis with delayed failure of the surgery, along with a discussion of recent advances in the management of this condition. CASE  PRESENTATION: A 9-year-old boy was referred to our hospital for traumatic amputation of the penis...
October 10, 2017: BMC Urology
https://www.readbyqxmd.com/read/28993147/techniques-of-ectopic-reservoir-placement-and-their-pitfalls
#14
Nannan Thirumavalavan, Martin S Gross, Ricardo Munarriz
BACKGROUND: Ectopic placement of penile prosthesis reservoirs has become more common in patients whose space of Retzius has been compromised. AIM: To describe techniques and instruments used to place penile prosthesis reservoirs ectopically. METHODS: We present our method of placing ectopic reservoirs and review the literature for other techniques. We also catalog the instruments used for this purpose. OUTCOMES: Similar to traditional reservoir placement, successful ectopic reservoir implantation requires good cosmetic and functional success and low complication rates...
October 6, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28982618/three-piece-penile-prosthesis-implantation-in-refractory-ischemic-priapism-tips-and-tricks
#15
Raul I Clavijo, Luís Felipe Sávio, Nachiketh Soodana Prakash, Thomas Masterson, J Francois Eid, Ranjith Ramasamy
INTRODUCTION AND OBJECTIVES: Implantation of a penile prosthesis in a patient with significant corporal fibrosis can pose a significant challenge to the surgeon, necessitating the knowledge of specific techniques used to dilate and close aggressively scarred corpora. The objective of our instructional video is to discuss 2 techniques used to approach corporal fibrosis: proper and safe use of cavernotomes for dilation and use of narrower prostheses. METHODS: In this video, we present a 53-year-old man with a history of priapism 3 years ago that lasted 4 days in the setting of trazodone use...
August 2017: Urology
https://www.readbyqxmd.com/read/28965315/surgical-techniques-for-managing-post-prostatectomy-erectile-dysfunction
#16
REVIEW
Fabio Castiglione, David J Ralph, Asif Muneer
PURPOSE OF REVIEW: Due to the increasing numbers of radical prostatectomies (RP) performed for prostate cancer, a substantial number of patients are now suffering from post-operative erectile dysfunction (ED). The aim of this study is to summarize the current literature on surgical techniques for managing post-prostatectomy erectile dysfunction. RECENT FINDINGS: The PubMed database was searched for English-language articles published up to Jan 2017 using the following search terms: "prostatectomy AND erectile dysfunction", "prostatectomy AND penile prostheses", and "prostatectomy AND penile implants"...
September 30, 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28959941/nondegloving-technique-for-peyronie-s-disease-with-penile-prosthesis-implantation-and-double-dorsal-ventral-patch-graft
#17
Andrew Fang, Run Wang
No abstract text is available yet for this article.
September 29, 2017: Asian Journal of Andrology
https://www.readbyqxmd.com/read/28952696/-buccal-mucosa-transplant-the-concept-of-ideal-graft-in-surgical-management-of-peyronies-disease
#18
S V Kotov, A G Yusufov, M K Semenov
INTRODUCTION: Surgical techniques in managing Peyronies disease include plication corporoplasty, plaque incision, grafting and penile prosthesis implantation. The question of an ideal transplant for corporoplasty remains open. AIM: To evaluate the effectiveness of the substitution corporoplasty using buccal mucosa transplant (BMT) in treating Peyronies disease. MATERIALS AND METHODS: From January 2011 to February 2016, 28 patients with stable stage Peyronies disease underwent substitution coroproplasty using BMT (incision and grafting)...
September 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28940910/the-outcomes-of-inflatable-penile-prosthesis-insertion-in-247-patients-completing-female-to-male-gender-reassignment-surgery
#19
M Falcone, G Garaffa, A Gillo, D Dente, A N Christopher, D J Ralph
OBJECTIVES: To assess the oucomes of penile prosthesis (PP) implantation after total phallic reconstruction secondary to gender dysphoria (GD). SUBJECT/PATIENTS AND METHODS: We conducted a retrospective single center analysis of 247 consecutive patients. The recruitment time was between January 2001 and October 2015. A total of 328 inflatable PP were implanted. A two-staged inflatable PP implantation was carried out. As a first step, an extraperitoneal reservoir placement was performed simultaneously with the glans sculpture and the insertion of a single large testicular prosthesis into the labia majora...
September 23, 2017: BJU International
https://www.readbyqxmd.com/read/28920056/management-of-refractory-ischemic-priapism-current-perspectives
#20
REVIEW
Marco Capece, Arianna Gillo, Andrea Cocci, Giulio Garaffa, Massimiliano Timpano, Marco Falcone
OBJECTIVES: The aim of the present manuscript is to review the current literature on priapism, focusing on the state-of-the-art knowledge of both the diagnosis and the treatment of the refractory ischemic priapism (IP). METHODS: Pubmed and EMBASE search engines were used to search for words "priapism", "refractory priapism", "penile prosthesis", "diagnosis priapism", "priapism treatment", "penile fibrosis", "priapism therapy". All the studies were carefully examined by the authors and then included in the review...
2017: Research and Reports in Urology
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