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Peyronie disease

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https://www.readbyqxmd.com/read/27909612/nonsurgical-treatment-options-in-peyronie-s-disease-2016-update
#1
REVIEW
Raidh A Talib, Mohammed Abdulkareem Ibrahim, Önder Cangüven
Peyronie's disease (PD) is an inflammatory condition of penile tunica albuginea which commonly ends with penile curvature and difficulty in vaginal penetration. Unfortunately, the pathophysiology of PD has not been completely understood. In this paper, we will review what is known about the pathophysiology of PD and the nonsurgical medical treatment options that have been trialed as a result. In the last 5 years, commonly used oral medications left their places to intralesional therapies. Clostridium collagenase, which is the only Food and Drug Administration (FDA) approved treatment for PD, is now the most prescribed intralesional therapy in the last years...
December 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27872029/association-between-infertility-and-sexual-dysfunction-in-men-and-women
#2
REVIEW
Michael H Berger, Marisa Messore, Alexander W Pastuszak, Ranjith Ramasamy
INTRODUCTION: The relation between infertility and sexual dysfunction can be reciprocal. Causes of sexual dysfunction that affect fertility include erectile dysfunction, Peyronie's disease (abnormal penile curvature), low libido, ejaculatory disorders in men, and genito-pelvic pain/penetration disorder (GPPPD) and low sexual desire in women. AIM: To review the association between infertility and sexual dysfunction and discuss current management strategies to address sexual disorders in couples with infertility...
October 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27872008/the-genetic-basis-of-peyronie-disease-a-review
#3
REVIEW
Amin S Herati, Alexander W Pastuszak
INTRODUCTION: Peyronie disease (PD) is a progressive fibrotic disorder of the penile tunica albuginea that results in fibrotic penile plaques and can lead to penile deformity. Characterized by aberrant fibrosis resulting in part from the persistence of myofibroblasts and altered gene expression, the molecular factors underpinning PD and other related fibrotic diatheses are just being elucidated. A genetic link to PD was first identified three decades ago using pedigree analyses. However, the specific genetic factors that predispose patients to aberrant fibrosis remain unknown, and the relations between these fibrotic conditions and other heritable diseases, including malignancy, are uncharacterized...
January 2016: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/27867021/patient-reported-long-term-sexual-outcomes-following-plication-surgery-for-penile-curvature-a-retrospective-58-patient-study
#4
A Baldini, N Morel-Journel, P Paparel, A Ruffion, J-E Terrier
OBJECTIVE: To evaluate long-term sexual function results following plication surgery for the correction of penile curvature using patient questionnaires. METHODS: We performed a single-center, retrospective study in a cohort of patients with Peyronie's disease or congenital penile curvature. All patients who underwent plication surgery on the convex aspect using the Nesbit, Yachia or diamond-shaped techniques were included. At a mean 34 months after the interventions, the patients were asked to respond to the IIEF5 questionnaire and a 19-item questionnaire...
November 18, 2016: Progrès en Urologie
https://www.readbyqxmd.com/read/27864619/bicentric-prospective-evaluation-of-corporoplasty-with-porcine-small-intestinal-submucosa-sis-in-patients-with-severe-peyronie-s-disease
#5
K Sayedahmed, B Rosenhammer, P J Spachmann, M Burger, M Aragona, B T Kaftan, R Olianas, H M Fritsche
INTRODUCTION: Advanced Peyronie's disease (PD) with severe penile deviation demands grafting procedures following plaque incision or partial plaque excision in order to avoid penile shortening and to improve quality of life of affected patients. Small intestinal submucosa (SIS) is an established xenograft. The objective of the present study was to validate external results in a bicentric prospective manner. METHODS: Patient selection criteria, surgical technique and standards for pre- and postoperative care were defined...
November 18, 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27845111/re-outcomes-of-surgical-management-of-men-with-peyronie-s-disease-with-hourglass-deformity
#6
Allen F Morey
No abstract text is available yet for this article.
December 2016: Journal of Urology
https://www.readbyqxmd.com/read/27825744/small-intestinal-submucosa-grafting-for-peyronie-s-disease-outcomes-and-patient-satisfaction
#7
Pedro Valente, Carolina Gomes, Nuno Tomada
OBJECTIVES: To evaluate surgical outcomes and complications and assess overall patient satisfaction after small intestinal submucosa (SIS) grafting for PD. METHODS: Twenty-eight patients were treated with tunical incision and grafting with SIS. Mean age was 58 years (range:43-71). A preoperative protocol was applied to all patients. Patients were also evaluated at follow-up clinic visits. The International Index of Erectile Function (IIEF-5), a modified Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) questionnaire, postoperative self-reports and clinical characteristics were used to measure outcomes...
November 4, 2016: Urology
https://www.readbyqxmd.com/read/27816605/impact-of-number-of-cycles-of-collagenase-clostridium-histolyticum-on-outcomes-in-patients-with-peyronie-s-disease
#8
James Anaissie, Faysal A Yafi, Kenneth J DeLay, Elizabeth J Traore, Suresh C Sikka, Wayne J G Hellstrom
OBJECTIVE: To analyze the impact of the number of cycles of collagenase Clostridium histolyticum (CCH) intralesional injection therapy on outcomes in order to further characterize CCH therapy. METHODS: We conducted a retrospective review of the records of all patients treated with CCH for PD between 04/2014 and 03/2016. Collected variables included demographics, pre- and post-treatment sexual function, penile curvature, penile vascular findings, and treatment outcomes...
November 2, 2016: Urology
https://www.readbyqxmd.com/read/27813380/data-vs-dogma-in-peyronie-s-disease
#9
EDITORIAL
Ryan P Terlecki, Alison M Rasper
No abstract text is available yet for this article.
November 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27770853/external-mechanical-devices-and-vascular-surgery-for-erectile-dysfunction
#10
Landon W Trost, Ricardo Munarriz, Run Wang, Allen Morey, Laurence Levine
INTRODUCTION: The field of sexual medicine is continuously advancing, with novel outcomes reported on a regular basis. Given the rapid evolution, updated guidelines are essential to inform practicing clinicians on best practices. AIM: To summarize the current literature and provide clinical guidelines on penile traction therapy, vacuum erection devices, and penile revascularization. METHODS: A consensus panel was held with leading sexual medicine experts during the 2015 International Consultation on Sexual Medicine (ICSM)...
November 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27770352/collagenase-clostridium-histolyticum-for-the-treatment-of-peyronie-s-disease-a-real-world-clinical-perspective
#11
James Anaissie, Wayne J G Hellstrom, Faysal A Yafi
The introduction of collagenase Clostridium histolyticum (CCH) as a treatment option for Peyronie's disease (PD), defined as the abnormal formation of collagen on the tunica albuginea of the penis, has provided patients with a promising new conservative therapy. Studies have shown that CCH improves curvature by an average of 17°, and although patient and sexual partner satisfaction is high, the improvement has arguable clinical implications. Similarly, the efficacy and cost of CCH contrasts strongly with more invasive surgical management, and is further limited by rare, but serious, complications and several contraindications...
October 21, 2016: Drugs
https://www.readbyqxmd.com/read/27751484/re-an-analysis-of-case-logs-from-american-urologists-in-the-treatment-of-peyronie-s-disease
#12
Allen F Morey
No abstract text is available yet for this article.
November 2016: Journal of Urology
https://www.readbyqxmd.com/read/27751478/re-female-partners-of-men-with-peyronie-s-disease-have-impaired-sexual-function-satisfaction-and-mood-while-degree-of-sexual-interference-is-associated-with-worse-outcomes
#13
https://www.readbyqxmd.com/read/27746896/-recent-advances-in-managing-peyronie-s-disease
#14
Oliver Kayes, Rauf Khadr
Peyronie's disease remains an under-reported and debilitating problem which can result in significant physical and psychological symptoms for some men. The classic symptom complex includes penile curvature, penile plaque, and penile pain. Men can also present with erectile dysfunction, penile instability, and penile shortening, alongside feelings of low mood/libido, dysmorphobia, and low self-esteem. This review highlights the current key publications in the medical literature and provides updates on new clinical therapies whilst postulating about potential future treatments on the horizon...
2016: F1000Research
https://www.readbyqxmd.com/read/27649111/a-wet-dressing-for-male-genital-surgery-a-phase-ii-clinical-trial
#15
Fábio de Oliveira Vilar, Flávia Cristina Morone Pinto, Amanda Vasconcelos Albuquerque, Ana Gabriela Santos Martins, Luiz Alberto Pereira de Araújo, José Lamartine de Andrade Aguiar, Salvador Vilar Correia Lima
PURPOSE: This study was to confirm the safety and efficacy of BC dressing when used in surgical male wound healing at the urogenital area. METHODS: Open, non-controlled clinical study of phase II. A total of 141 patients, among those children, adolescents and adults with hypospadias (112), epispadias (04), phymosis (13) and Peyronie's disease (12) that had a BC dressing applied over the operated area after surgery. A written informed consent was obtained from all participants...
November 2016: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/27628826/re-use-of-a-lyophilized-bovine-pericardium-graft-to-repair-tunical-defect-in-patients-with-peyronie-s-disease-experience-in-a-clinical-setting
#16
Allen D Seftel
No abstract text is available yet for this article.
October 2016: Journal of Urology
https://www.readbyqxmd.com/read/27628825/re-the-prevalence-of-peyronie-s-disease-in-the-united-states-a%C3%A2-population-based-study
#17
Allen D Seftel
No abstract text is available yet for this article.
October 2016: Journal of Urology
https://www.readbyqxmd.com/read/27628824/re-outcomes-of-surgical-management-of-men-with-peyronie-s-disease-with-hourglass-deformity
#18
Allen D Seftel
No abstract text is available yet for this article.
October 2016: Journal of Urology
https://www.readbyqxmd.com/read/27574590/nonsurgical-interventions-for-peyronie-s-disease-update-as-of-2016
#19
REVIEW
Gregory A Joice, Arthur L Burnett
Peyronie's disease (PD) is a debilitating condition of the penis that leads to significant pain, erectile dysfunction, and emotional distress in men. PD is likely underreported due to lack of knowledge of the disease and the absence of well-established available treatments. Surgical treatment can lead to sustained improvements, but is often associated with penile shortening and places the patient at risk for perioperative morbidity. Nonsurgical management has been studied for several years as an alternative to surgery for men with PD...
August 2016: World Journal of Men's Health
https://www.readbyqxmd.com/read/27567204/re-a-meta-analysis-of-extracorporeal-shock-wave-therapy-for-peyronie-s-disease
#20
Amanda B Reed-Maldonado, Tom F Lue
No abstract text is available yet for this article.
August 23, 2016: European Urology
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