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https://www.readbyqxmd.com/read/27889781/striated-muscle-in-radical-prostatectomy-specimens-a-marker-of-apical-dissection-quality-and-an-independent-predictor-of-urinary-continence-after-endoscopic-extraperitoneal-radical-prostatectomy
#1
Daniel W Good, Andrew Wood, Laurence Stewart, Jens-Uwe Stolzenburg, Roman Ganzer, Jochen Neuhaus, Grant D Stewart, S Alan McNeill
INTRODUCTION: The study aimed to determine if the presence and amount of striated muscle on the apical sections of the cruciate sections of laparoscopic radical prostatectomy (LRP) specimens predict early and long-term urinary continence outcomes. PATIENTS AND METHODS: We conducted a retrospective review of our prospectively collected single surgeon LRP database. We identified patients based on their continence outcomes (continent (0 pads) or incontinent at 12 months), with an approximate even spread early continent and incontinent patients)...
November 26, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27882057/robotic-assisted-laparoscopic-prostatectomy-performed-after-previous-suprapubic-prostatectomy
#2
Johnson F Tsui, Michael Feuerstein, Seyed Behzad Jazayeri, David B Samadi
Operative management of prostate cancer in a patient who has undergone previous open suprapubic simple prostatectomy poses a unique surgical challenge. Herein, we describe a case of intermediate risk prostate cancer in a man who had undergone simple prostatectomy ten years prior to presentation. The patient was found to have Gleason 7 prostate cancer on MRI fusion biopsy of the prostate for elevated PSA and underwent an uncomplicated robot assisted laparoscopic radical prostatectomy.
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27785630/single-incision-laparoscopic-transabdominal-preperitoneal-mesh-hernioplasty-results-in-182-japanese-patients
#3
K Tanoue, H Okino, M Kanazawa, K Ueno
BACKGROUND: We introduced single-incision transabdominal preperitoneal (S-TAPP) herniorrhaphy (described herein) at our institution in June 2010. We recently conducted a retrospective study to assess the feasibility and safety of the procedure. METHODS: The study involved 182 patients (159 men, 23 women) who underwent S-TAPP herniorrhaphy between June 2010 and February 2015 for 202 groin hernias (162 unilateral hernias, 20 bilateral hernias). We examined patient characteristics, hernia type and presentation, operation time, conversion to another repair procedure, intraoperative blood loss, postoperative pain, morbidities, and postoperative hospital stay...
October 26, 2016: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/27785527/-long-term-results-after-robot-assisted-adenoma-enucleation
#4
A Häcker, J W Thüroff
For selected patients with large-volume prostates, open simple prostatectomy is an effective and durable treatment option. Robot-assisted simple prostatectomy potentially reduces intraoperative blood loss, transfusion rates, length of hospital stay, and complications, but has longer operative times. In all, 16 series with level 3 evidence have been published and demonstrated its safety and efficacy. Long-term data are lacking and comparative outcome studies are needed to establish its benefits compared to open, simple prostatectomy and transurethral laser enucleation techniques...
October 26, 2016: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/27775165/predicting-prostate-cancer-recurrence-after-radical-prostatectomy
#5
Abra Jeffers, Vanessa Sochat, Michael W Kattan, Changhong Yu, Erin Melcon, Kosi Yamoah, Timothy R Rebbeck, Alice S Whittemore
BACKGROUND: Prostate cancer prognosis is variable, and management decisions involve balancing patients' risks of recurrence and recurrence-free death. Moreover, the roles of body mass index (BMI) and race in risk of recurrence are controversial [1,2]. To address these issues, we developed and cross-validated RAPS (Risks After Prostate Surgery), a personal prediction model for biochemical recurrence (BCR) within 10 years of radical prostatectomy (RP) that includes BMI and race as possible predictors, and recurrence-free death as a competing risk...
October 24, 2016: Prostate
https://www.readbyqxmd.com/read/27764770/visualization-of-early-prostatic-adenocarcinoma-as-a-stem-cell-disease
#6
Maggie Y Jiang, Tammy L Lee, Su-Shin Hao, Sepi Mahooti, Stephen M Baird, Daniel J Donoghue, Martin Haas
Prostate Cancer represents the second leading cause of cancer death among men in the United States, and the third leading cause of cancer death among men in Europe. We have previously shown that cells possessing Cancer Stem Cell (CSC) characteristics can be grown from human PrCa tissue harvested at the time of prostatectomy. However, the cellular origin of these CSCs was not previously known. In most cases, simple hematoxylin and eosin (H&E) stained sections are sufficient to make a definitive diagnosis of prostatic adenocarcinoma (PrCa) in needle biopsy samples...
October 18, 2016: Oncotarget
https://www.readbyqxmd.com/read/27713790/mapping-a-competency-based-surgical-curriculum-in-urology-agreement-and-discrepancies-in-the-canadian-national-opinion
#7
Keith Francis Rourke, Andrew E MacNeily
INTRODUCTION: Urology residency training in Canada is quickly evolving from a time-based to a competency-based model. We aim to better define core surgical competencies that would comprise a surgical curriculum and assess any discrepancies in opinion nationally. METHODS: A web-based survey was validated and sent to the 536 practicing members of the Canadian Urological Association (CUA) in August and October 2014. The survey consisted of questions regarding practice demographics, fellowship training, and evaluated the 76 most common urological procedures (using a five-point Likert scale) in the context of the question, "After completion of residency training in Canada a urologist should be proficient in…" A core procedure was defined as one for which there was ≥75% agreement...
May 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27699877/laparoendoscopic-single-site-surgeries-a-multicenter-experience-of-469-cases-in-japan
#8
Fuminori Sato, Ken Nakagawa, Akihiro Kawauchi, Akio Matsubara, Takatsugu Okegawa, Tomonori Habuchi, Koji Yoshimura, Akio Hoshi, Hidefumi Kinoshita, Akira Miyajima, Yasuyuki Naitoh, Shogo Inoue, Naoshi Itaya, Shintaro Narita, Kazuya Hanai, Kazutoshi Okubo, Masaaki Yanishi, Tadashi Matsuda, Toshiro Terachi, Hiromitsu Mimata
OBJECTIVE: To report on a multi-institutional series of non-robotic urological laparoendoscopic single-site surgery in Japan. METHODS: Consecutive cases of laparoendoscopic single-site surgery carried out between February 2009 and December 2012 at nine academic institutions were included. We examined the surgical outcomes, including conversion and complications rates. RESULTS: Four hundred and sixty-nine cases were included in the analysis...
October 4, 2016: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/27628817/re-perioperative-outcomes-of-robotic-and-laparoscopic-simple-prostatectomy-a-european-american-multi-institutional-analysis
#9
Steven A Kaplan
No abstract text is available yet for this article.
October 2016: Journal of Urology
https://www.readbyqxmd.com/read/27615435/robotic-assisted-simple-prostatectomy-rasp-versus-holmium-laser-enucleation-of-the-prostate-holep-for-lower-urinary-tract-symptoms-in-patients-with-large-volume-prostates-100-ml-a-comparative-analysis-from-a-high-volume-center
#10
Paolo Umari, Nicola Fossati, Giorgio Gandaglia, Morgan Pokorny, Ruben De Groote, Nicolas Geurts, Marijn Goossens, Peter Schatterman, Geert De Naeyer, Alexandre Mottrie
OBJECTIVE: To report a comparative analysis of Robotic-assisted Simple Prostatectomy (RASP) versus Holmium Laser Enucleation of Prostate (HoLEP) in Benign Prostatic Hyperplasia (BPH) patients with large volume prostates (>100ml). MATERIAL AND METHODS: 81 patients underwent RASP and 45 underwent HoLEP over a 7-year period. Patients were preoperatively assessed with transrectal ultrasound and uroflowmetry. Functional parameters were assessed postoperatively during the follow-up...
September 8, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27587651/a-simple-psa-based-computational-approach-predicts-the-timing-of-cancer-relapse-in-prostatectomized-patients
#11
Ilaria Stura, Domenico Gabriele, Caterina Guiot
Recurrences of prostate cancer affect approximately one quarter of patients who have undergone radical prostatectomy. Reliable factors to predict time to relapse in specific individuals are lacking. Here, we present a mathematical model that evaluates a biologically sensible parameter (α) that can be estimated by the available follow-up data, in particular by the PSA series. This parameter is robust and highly predictive for the time to relapse, also after administration of adjuvant androgen deprivation therapies...
September 1, 2016: Cancer Research
https://www.readbyqxmd.com/read/27585786/enucleation-is-enucleation-is-enucleation-is-enucleation
#12
EDITORIAL
Thomas R W Herrmann
The latest update of the EAU Guidelines on Management of Non-Neurogenic Male Lower Urinary Tract Symptoms, incl. Benign Prostatic Obstruction in 2016 announced a novel acronym for transurethral Endoscopic Enucleation of the Prostate (EEP). This was inspired by a meta-analysis on randomized controlled trials on Holmium Laser Enucleation of the Prostate (HolEP) and bipolar enucleation versus open simple prostatectomy. EEP codes for the common ground of both techniques: "anatomical enucleation." Although study quality with regard to the availability of long-term randomized controlled trials is at the moment mostly available for HoLEP, and bipolar enucleation, the existing data of all other enucleating techniques that have been demonstrated to perform anatomical enucleation as well should also been summarized under the same term...
October 2016: World Journal of Urology
https://www.readbyqxmd.com/read/27519277/an-easily-applicable-single-condition-based-mortality-index-for-patients-undergoing-radical-prostatectomy-or-radical-cystectomy
#13
Michael Froehner, Rainer Koch, Ulrike Heberling, Vladimir Novotny, Matthias Hübler, Manfred P Wirth
PURPOSE: There is no generally accepted instrument to measure comorbidity in patients with cancer. We determined which single comorbid conditions are independently associated with competing mortality after radical prostatectomy or radical cystectomy in order to develop a mortality index. METHODS: The study samples consisted of 2,961 consecutive patients who underwent radical prostatectomy between 1992 and 2007 for clinically localized prostate cancer and 932 consecutive patients who underwent radical cystectomy between 1993 and 2012 for high-risk non-muscle-invasive or muscle-invasive urothelial or undifferentiated bladder cancer...
August 9, 2016: Urologic Oncology
https://www.readbyqxmd.com/read/27498197/incidence-risk-factors-and-a-novel-prevention-technique-for-inguinal-hernia-after-robot-assisted-radical-prostatectomy
#14
Masaki Shimbo, Fumiyasu Endo, Kazuhito Matsushita, Toshihisa Iwabuchi, Akiko Fujisaki, Yoko Kyono, Kohsuke Hishiki, Osamu Muraishi, Kazunori Hattori
INTRODUCTION: To evaluate the incidence and risk factors for postoperative inguinal hernia (IH) after robot-assisted radical prostatectomy (RARP) and to assess whether a newly developed prevention technique reduces the incidence of IH after RARP. METHODS: We included 161 consecutive patients (322 groins) who underwent RARP between September 2011 and October 2013. The prevention technique was as follows: (1) sufficient incision of peritoneum around the internal inguinal ring; (2) separation of spermatic vessels; (3) dissection of vas deferens...
August 6, 2016: Urologia Internationalis
https://www.readbyqxmd.com/read/27476131/robotic-assisted-simple-prostatectomy-an-overview
#15
REVIEW
Marc Holden, J Kellogg Parsons
Despite widespread use of medical therapy for benign prostatic hyperplasia, a need remains for robust surgical therapy in select patients. Robotic-assisted simple prostatectomy (RASP) is an efficacious and safe therapy for patients with bladder outlet obstruction owing to large volume prostates. Data from 13 published cohorts suggest functional outcomes equivalent to open simple prostatectomy with substantially decreased length of hospital stay and risk of transfusion. However, there are few longer term data...
August 2016: Urologic Clinics of North America
https://www.readbyqxmd.com/read/27432378/the-impact-of-central-obesity-on-storage-luts-and-urinary-incontinence-after-prostatic-surgery
#16
REVIEW
Mauro Gacci, Arcangelo Sebastianelli, Matteo Salvi, Cosimo De Nunzio, Andrea Tubaro, Stavros Gravas, Ignacio Moncada, Sergio Serni, Mario Maggi, Linda Vignozzi
In the developed and developing countries, the overall prevalence of central obesity in the elderly men is growing. In addition, the progressive aging of male population increased the possibilities of coexisting morbidities associated with obesity such as lower urinary tract symptoms (LUTS) due to benign prostatic enlargement (BPE) or to prostate cancer (PCa) needing primary treatment, including radical prostatectomy (RP), which can further adversely affect the quality of life. Simple and radical prostatectomy are the most common surgical procedures in urologic unit all over the world for BPE and PCa, respectively...
September 2016: Current Urology Reports
https://www.readbyqxmd.com/read/27370230/can-atorvastatin-with-metformin-change-the-natural-history-of-prostate-cancer-as-characterized-by-molecular-metabolomic-imaging-and-pathological-variables-a-randomized-controlled-trial-protocol
#17
Matthew J Roberts, John W Yaxley, Geoffrey D Coughlin, Troy R J Gianduzzo, Rachel C Esler, Nigel T Dunglison, Suzanne K Chambers, Robyn J Medcraft, Clement W K Chow, Horst Joachim Schirra, Renee S Richards, Nicholas Kienzle, Macy Lu, Ian Brereton, Hema Samaratunga, Joanna Perry-Keene, Diane Payton, Chikara Oyama, Suhail A Doi, Martin F Lavin, Robert A Gardiner
BACKGROUND: Atorvastatin and metformin are known energy restricting mimetic agents that act synergistically to produce molecular and metabolic changes in advanced prostate cancer (PCa). This trial seeks to determine whether these drugs favourably alter selected parameters in men with clinically-localized, aggressive PCa. METHODS/DESIGN: This prospective phase II randomized, controlled window trial is recruiting men with clinically significant PCa, confirmed by biopsy following multiparametric MRI and intending to undergo radical prostatectomy...
September 2016: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/27358846/modified-urethrovesical-anastomosis-during-robot-assisted-simple-prostatectomy-technique-and-results
#18
Octavio Castillo, Ivar Vidal-Mora, Arquimedes Rodriguez-Carlin, Andres Silva, Oscar Schatloff
BACKGROUND: Despite significant developments in transurethral surgery for benign prostatic hyperplasia, simple prostatectomy remains an excellent option for patients with severely enlarged glands. The objective is to describe our results of robot-assisted simple prostatectomy (RASP) with a modified urethrovesical anastomosis (UVA). METHODS: From May 2011 to February 2014, RASP with UVA was performed in 34 patients by a single surgeon (O.C.) using the da Vinci S-HD surgical system...
June 2016: Prostate International
https://www.readbyqxmd.com/read/27310968/the-impact-of-surgical-treatments-for-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia-on-male-erectile-function-a-systematic-review-and-network-meta-analysis
#19
Zhuo Li, Ping Chen, Jun Wang, Qi Mao, Han Xiang, Xiao Wang, Xinghuan Wang, Xinhua Zhang
Lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH) is common in adult men and can impair erectile function (EF). It was believed surgical treatments for this illness can improve EF due to the relief of LUTS while they were also reported harmed EF as heating or injury effect. Current network meta-analysis aimed to elucidate this discrepancy.Randomized controlled trials (RCTs) were identified. Direct comparisons were conducted by STATA and network meta-analysis was conducted by Generate Mixed Treatment Comparison...
June 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27294802/trends-in-simple-prostatectomy-for-benign-prostatic-hyperplasia
#20
REVIEW
Joseph J Pariser, Vignesh T Packiam, Melanie A Adamsky, Gregory T Bales
The definitive treatment for symptomatic large volume (>80 mL) benign prostatic hyperplasia (BPH) is simple prostatectomy (SP). This can be performed by utilizing a retropubic, suprapubic, or a combined approach. The latter two approaches allow for the management of concomitant bladder diverticulum or stones through the same incision. Each approach affords unique technical strengths and weaknesses that must be considered in light of patient characteristics and concomitant pathology. SP allows for removal of the entire prostatic adenoma while obviating some of the neurovascular and continence issues that can arise from radical prostatectomy...
August 2016: Current Urology Reports
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