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Adenoma of the prostate

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https://www.readbyqxmd.com/read/29775699/relationship-between-intraprostatic-urethral-sphincter-status-and-prostate-volume-as-revealed-by-magnetic-resonance-imaging
#1
Fumiyasu Endo, Kazuhiro Ohwaki, Masaki Shimbo, Kazunori Hattori
OBJECTIVES: To evaluate the relationship between the lengths of two regions of the intraprostatic urethral sphincter, the distal region (from the apex to the adenoma; AA) and the proximal region (from the adenoma to the verumontanum; AV) and prostate volume (PV) in patients with clinical benign prostate hyperplasia. METHODS: A total of 110 patients who underwent magnetic resonance imaging (MRI) prior to holmium laser enucleation of the prostate were enrolled. The lengths of two distinct intraprostatic urethral regions were measured on MRI, and we used multiple regression analysis to explore the association between these lengths and PV...
May 15, 2018: Urology
https://www.readbyqxmd.com/read/29698941/computer-assisted-quantitative-assessment-of-prostatic-calcifications-in-patients-with-chronic-prostatitis
#2
Matteo Boltri, Vittorio Magri, Emanuele Montanari, Gianpaolo Perletti, Alberto Trinchieri
BACKGROUND: The aim of this study was the development of quantitative assessment of prostatic calcifications at prostatic ultrasound examination by the use of an image analyzer. MATERIALS AND METHODS: A group of 82 patients was evaluated by medical history, physical, and transrectal ultrasound examination. Patients had a urethral swab, a 4-specimen study and culture of the seminal fluid. Patients were classified according to National Institute of Diabetes and Digestive and Kidney Diseases/National Institutes of Health...
April 26, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29694702/aquablation-procedural-outcomes-for-bph-in-large-prostates-80-150cc-initial-experience
#3
Mihir Desai, Mo Bidair, Naeem Bhojani, Andrew Trainer, Andrew Arther, Eugene Kramolowsky, Leo Doumanian, Dean Elterman, Ronald P Kaufman, James Lingeman, Amy Krambeck, Gregg Eure, Gopal Badlani, Mark Plante, Edward Uchio, Greg Gin, Larry Goldenberg, Ryan Paterson, Alan So, Mitch Humphreys, Claus Roehrborn, Steven Kaplan, Jay Motola, Kevin C Zorn
BACKGROUND AND AIMS: To present early safety and feasibility data from a multicenter prospective study of Aquablation in treatment of symptomatic men with large volume BPH. METHODS: Between September and December 2017, 101 men with moderate-to-severe BPH symptoms and prostate volume of 80-150cc underwent Aquablation in a prospective multicenter international clinical trial. Baseline demographics and standardized postoperative management parameters were carefully recorded in a central independently monitored database...
April 25, 2018: BJU International
https://www.readbyqxmd.com/read/29663940/ezh2-expression-in-naturally-occurring-canine-tumors
#4
Hyun-Ji Choi, Han-Byul Lee, Hyun-Kyu Park, Sung-Min Cho, Hyo-Jeong Han, Sang-Joon Lee, Ji-Young Lee, Su-Jeong Nam, Eun-Ho Cho, Woo-Chan Son
Enhancer of zeste homolog 2 (EZH2) shows upregulated expression in tumors and is an important driver of tumor development and progression. However, the mechanism underlying the mediation of tumor aggressiveness by EZH2 remains unclear. We here investigated the levels of EZH2 in various normal and tumorous dog tissues and compared these patterns with those of the corresponding human tissues. Immunohistochemical analysis showed positive staining for EZH2 in 76 of 82 cases of canine tumors, whereas low or negligible staining occurred in normal tissues and other canine tumors, including hepatocellular adenoma and lipoma...
April 2, 2018: Comparative Medicine
https://www.readbyqxmd.com/read/29617077/robotic-adenomectomy-using-a-laparoscopic-dissector
#5
Lessandro Curcio Gonçalves, Felipe Monnerat Lott, Rafael Rosa
INTRODUCTION: Only few reports are known about the use of robotic surgery for prostate benign enlargement. The robotic surgery can be improved by laparoscopic tricks. We show a video of robotic adenomectomy where a laparoscopic dissector is used to help create the plan between prostatic capsule and adenoma. MATERIALS AND METHODS: A 62 years old male had severe urinary flow outlet obstruction. Medical therapy was not effective. Ultrasound detected a 92gr enlarged prostate with a large middle lobe...
March 15, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29573104/transvesical-robotic-simple-prostatectomy-with-360%C3%A2-circumferential-reconstruction-step-by-step-technique
#6
G E Cacciamani, L G Medina, A N Ashrafi, H Landsberger, M Winter, P Mekail, M M Desai, M Aron, A K Berger
OBJECTIVE: To present a step-by-step technique of a 360-degree mucosal reconstruction after robotic transvesical simple prostatectomy (RSP). PATIENT AND METHODS: We analysed first 23 consecutive patients who underwent RSP using our 360-degree reconstruction between December 2015 to October 2017. Following the transperitoneal intravesical adenoma enucleation, a circumferential 360-degree reconstruction with 2-0 V-loc suture is performed. The first suture is placed at the 9 o'clock position and the edge of the urethra and bladder mucosa is approximated using 2-0 V-loc suture The reconstruction is continued counter-clockwise and the bladder mucosa is approximated to the urethra circumferentially...
March 23, 2018: BJU International
https://www.readbyqxmd.com/read/29533281/a-case-of-a-malignant-cutaneous-mixed-tumor-chondroid-syringoma-of-the-scapula-treated-with-staged-margin-controlled-excision
#7
Karan Lal, Travis J Morrell, Michael Cunningham, Patrick OʼDonnell, Nikki A Levin, Kristine M Cornejo
Cutaneous mixed tumor (chondroid syringoma) is the cutaneous counterpart of pleomorphic adenoma of salivary glands, comprised of both epithelial and mesenchymal components. Malignant transformation is exceptionally rare, with only a few cases reported. We report a case of a malignant cutaneous mixed tumor in an 86-year-old white man who presented with a pink indurated plaque on his left scapula. He had a history of nonmelanoma skin cancers, a stage IB malignant melanoma of a lower extremity and Gleason 4 + 3 prostate cancer treated with brachytherapy, external beam irradiation, and bicalutamide...
March 6, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29515776/neovascular-psma-expression-is-a-common-feature-in-malignant-neoplasms-of-the-thyroid
#8
Birthe Heitkötter, Konrad Steinestel, Marcel Trautmann, Inga Grünewald, Peter Barth, Heidrun Gevensleben, Martin Bögemann, Eva Wardelmann, Wolfgang Hartmann, Kambiz Rahbar, Sebastian Huss
Aim: PSMA (prostate-specific membrane antigen) is physiologically expressed in normal prostate tissue and over expressed in prostate cancer cells, therefore constituting a potential target for antibody-based radioligand therapy. Very recent imaging findings reported PSMA-PET/CT uptake in various thyroid lesions. We were therefore encouraged to systematically analyse PSMA expression in different benign and malignant thyroid lesions. Methods: Immunohistochemistry was used to detect PSMA expression in 101 thyroid lesions, while neovasculature was identified by CD34 immunostaining...
February 9, 2018: Oncotarget
https://www.readbyqxmd.com/read/29484912/umbilical-lesions-clinicopathologic-features-of-99-tumors
#9
Lei Yan, Shenon Sethi, Pincas Bitterman, Vijaya Reddy, Paolo Gattuso
BACKGROUND: Umbilical lesions are rare, and can be benign or malignant. This retrospective study was conducted to assess the epidemiological, clinical, and histologic characteristics of umbilical masses. METHODS: Cases of umbilical masses from January 1994 to August 2016 were retrieved from our institution's pathology databases, and their clinicopathological features were reviewed. RESULTS: There were a total of 99 cases of umbilical masses, 78 women (78...
February 1, 2018: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29483498/expression-of-cancer-associated-genes-in-prostate-tumors
#10
E E Rosenberg, G V Gerashchenko, N V Hryshchenko, L V Mevs, K A Nekrasov, R A Lytvynenko, Y V Vitruk, O P Gryzodub, E A Stakhovsky, V I Kashuba
BACKGROUND:  Prostate cancer is one of the most common male cancers in Western countries and takes the third place in morbidity in Ukraine. It is a highly heterogeneous disease. AIM: To analyze relative expression levels of the TGFB1, IL1B, FOS, EFNA5, TAGLN, PLAU, and EPDR1 genes in malignant and non-malignant prostate tissues. MATERIALS AND METHODS:  Total RNA was isolated from 16 prostate adenomas, 37 prostate adenocarcinomas, and 29 conventionally normal prostate tissues...
July 2017: Experimental Oncology
https://www.readbyqxmd.com/read/29387557/patients-with-small-prostates-and-low-grade-intravesical-prostatic-protrusion-a-urodynamic-evaluation
#11
Han Jie Lee, Alvin Lee, Hong Hong Huang, Palaniappan Sundaram, Keong Tatt Foo
Objective: Despite high-grade intravesical prostatic protrusion (IPP) being closely related to bladder outlet obstruction (BOO), up to 21% of patients with low IPP remain obstructed. This study evaluates the characteristics and urodynamic findings of men with small prostates and low IPP. Methods: One hundred and fourteen men aged >50 years old with lower urinary tract symptoms (LUTS) were assessed with symptoms, uroflowmetry, serum prostate-specific antigen (PSA), transabdominal ultrasound measurement of prostate volume (PV), IPP and post-void residual urine (PVRU)...
October 2017: Asian Journal of Urology
https://www.readbyqxmd.com/read/29379735/laparoscopic-adenomectomy-in-bph-does-it-have-a-role-today
#12
REVIEW
Ramalingam Manickam, Sivasankaran Nachimuthu, Senthil Kallappan, Mizar G Pai
Symptomatic benign prostatic hyperplasia (BPH) is managed medically worldwide, but transurethral resection of prostate (TURP) is the gold standard in refractory cases. Holmium laser enucleation of prostate (HoLEP), laser vaporization are other options which are widely practiced. However in larger glands which are more than 80 g, open adenomectomy is still practiced. Laparoscopic adenomectomy is a minimally invasive option in such circumstances. This article explains about different techniques in minimally invasive adenomectomy and the role for this procedure today...
January 2018: Asian Journal of Urology
https://www.readbyqxmd.com/read/29376601/-comparative-assessment-of-treatments-for-prostate-adenoma-greater-than-100-cm3
#13
COMPARATIVE STUDY
I N Orlov, S V Popov, A G Martov, E A Gallyamov, S M Malevich, I V Sushina, E A Grin, A E Sanzharov, A B Novikov, V P Sergeev, A D Kochkin
AIM: To compare holmium laser enucleation of the prostate (HoLEP) and endovideosurgical (EVS) adenomectomy in the treatment of prostate adenoma. MATERIALS AND METHODS: We compared treatment results of 180 patients with prostate adenomas greater than 100 cm3 who underwent EVS adenomectomy (n=90) and laser enucleation of the prostate (n=90). The analysis included the following parameters: duration of catheterization, length of postoperative hospital stay, I-PSS score, maximum urinary flow rate measured by uroflowmetry and complications according to Clavien-Dindo grading systems...
December 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/29329896/open-prostatectomy-versus-180-w-xps-greenlight-laser-vaporization-long-term-functional-outcome-for-prostatic-adenomas-80-g
#14
C Lanchon, G Fiard, J-A Long, V Arnoux, D Carnicelli, Q Franquet, D Poncet, E Bey, J-B Lefrancq, S Grisard, N Peilleron, N Terrier, B Boillot, J-J Rambeaud, J-L Descotes, C Thuillier
INTRODUCTION: GreenLight photoselective vaporisation of the prostate (PVP) offers an endoscopic alternative to open prostatectomy (OP) for treatment of large adenomas. This study compares long-term functional outcome of both techniques in patients with Benign prostatic obstruction (BPO)>80g. MATERIAL AND METHOD: Data from patients who underwent surgical treatment for BPO>80g from January 2010 to February 2015 at our institution were retrospectively collected and compared according to surgical technique...
March 2018: Progrès en Urologie
https://www.readbyqxmd.com/read/29307091/low-pressure-monopolar-electroresection-of-the-prostate-for-glands-sized-70-vs-70-cc-performed-with-continuous-irrigation-and-suprapubic-suction-perioperative-and-long-term-outcome
#15
Konrad Wilhelm, Ioana Maria Cazana, Martin Schoenthaler, Arndt Katzenwadel, Johannes Spaeth, Arkadiusz Miernik
PURPOSE: To evaluate long-term efficacy and safety of low-pressure transurethral resection of the prostate for prostates < 70 cc (group 1) vs. > 70 cc (group 2). PATIENTS AND METHODS: In this study patients operated with monopolar TURP between 2009 and 2012 were evaluated retrospectively. During surgery a specially designed trocar (18 Fr) was placed suprapubically and connected to a suction pump to maintain stable low-pressure conditions. After sample size calculations, long-term follow-up was completed for 70 invited patients in each group up to 9/2015...
March 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29280253/association-between-dietary-pattern-scores-and-the-prevalence-of-colorectal-adenoma-considering-population-subgroups
#16
Alyson Haslam, Sara Wagner Robb, James R Hébert, Hanwen Huang, Mark H Ebell
AIM: The purpose of the current study is to examine the dietary patterns in a diverse cohort of individuals and to see if the identified dietary patterns predict the prevalence of adenoma in a cross-sectional study. METHODS: Factor analysis was used to derive both sex- and population subgroup-specific dietary patterns among participants in the screening arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial. Logistic regression was used to assess associations between identified factor scores and colorectal adenoma (CRA) in sex-specific subgroups...
December 26, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/29246283/greater-adherence-to-a-mediterranean-diet-is-associated-with-lower-prevalence-of-colorectal-adenomas-in-men-of-all-races
#17
Alyson Haslam, Sara Wagner Robb, James R Hébert, Hanwen Huang, Mark H Ebell
To examine potential racial differences in Mediterranean diet scores and whether these differences are associated with the prevalence of colorectal adenoma (CRA), a cross-sectional analysis of data from the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial was performed. The authors hypothesize that people consuming a more Mediterranean-like diet have lower odds of CRA. Flexible sigmoidoscopy was used to determine the presence of colorectal adenoma. Mediterranean diet scores were calculated from food frequency questionnaire responses...
December 2017: Nutrition Research
https://www.readbyqxmd.com/read/29234539/transurethral-bipolar-plasmakinetic-vapo-enucleation-of-the-prostate-is-it-safe-for-patients-on-chronic-oral-anticoagulants-and-or-platelet-aggregation-inhibitors
#18
Waleed El-Shaer, Ahmed Abou-Taleb, Wael Kandeel
Objectives: To assess the safety and efficacy of bipolar plasmakinetic enucleation and resection of the prostate (PKERP) for the management of benign prostatic hyperplasia (BPH) in patients on oral anticoagulant (OAC) therapy and/or platelet aggregation inhibitors (PAIs). Patients and methods: In all, 91 patients were recruited and underwent PKERP whilst they were receiving PAIs (aspirin, 56 patients; clopidogrel, three; aspirin and clopidogrel, 11). In all, 15 patients were receiving an OAC drug perioperatively, whilst another six patients were on dual PAIs and OACs...
December 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29225121/anatomical-control-of-adenoma-technique-an-accurate-surgical-approach-to-thulium-laser-enucleation-of-the-prostate
#19
Marco Dellabella, Daniele Castellani
OBJECTIVE: To present our 2-lobe technique of thulium laser transurethral enucleation of the prostate. Transurethral resection of prostate and open prostatectomy have been traditionally considered as the gold standard for benign prostatic enlargement surgical treatment. Laser has been recently made available for benign prostatic enlargement surgery to minimize morbidity of traditional surgery.1 In 2009, Bach et al introduced the use of thulium laser,2 describing the 3-lobe technique, which overlaps open prostatectomy but with a greater control of hemostasis...
December 7, 2017: Urology
https://www.readbyqxmd.com/read/29195552/geometric-and-dosimetric-quality-assurance-using-logfiles-and-a-3d-helical-diode-detector-for-dynamic-wavearc
#20
Hideaki Hirashima, Mitsuhiro Nakamura, Yuki Miyabe, Nobutaka Mukumoto, Megumi Uto, Kiyonao Nakamura, Takashi Mizowaki, Masahiro Hiraoka
PURPOSE: To conduct patient-specific geometric and dosimetric quality assurance (QA) for the Dynamic WaveArc (DWA) using logfiles and ArcCHECK (Sun Nuclear Inc., Melbourne, FL, USA). METHODS: Twenty DWA plans, 10 for pituitary adenoma and 10 for prostate cancer, were created using RayStation version 4.7 (RaySearch Laboratories, Stockholm, Sweden). Root mean square errors (RMSEs) between the actual and planned values in the logfiles were evaluated. Next, the dose distributions were reconstructed based on the logfiles...
November 2017: Physica Medica: PM
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