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https://www.readbyqxmd.com/read/28412568/first-report-on-mrsa-cc398-recovered-from-wild-boars-in-the-north-of-portugal-are-we-facing-a-problem
#1
Margarida Sousa, Nuno Silva, Vera Manageiro, Sónia Ramos, António Coelho, David Gonçalves, Manuela Caniça, Carmen Torres, Gilberto Igrejas, Patrícia Poeta
The aim of the present study was to evaluate the resistance of Staphylococcus aureus recovered from wild boars, to analyze their genetic lineages, and to investigate the susceptibility to oxacillin. Samples from mouth and nose of 45 wild boars (Sus scrofa) were collected during hunt activity from November 2012 to January 2013 in the North of Portugal. S. aureus isolates were recovered from 30 of these samples (33%); one isolate/sample was further studied. The susceptibility of the isolates was tested by disk-diffusion test against 14 antimicrobial agents and minimal inhibitory concentration was used to test oxacillin according to EUCAST guidelines...
April 13, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28379981/improved-costs-and-outcomes-with-conscious-sedation-vs-general-anesthesia-in-tavr-patients-time-to-wake-up
#2
William Toppen, Daniel Johansen, Sohail Sareh, Josue Fernandez, Nancy Satou, Komal D Patel, Murray Kwon, William Suh, Olcay Aksoy, Richard J Shemin, Peyman Benharash
BACKGROUND: Transcatheter aortic valve replacement (TAVR) has become a commonplace procedure for the treatment of aortic stenosis in higher risk surgical patients. With the high cost and steadily increasing number of patients receiving TAVR, emphasis has been placed on optimizing outcomes as well as resource utilization. Recently, studies have demonstrated the feasibility of conscious sedation in lieu of general anesthesia for TAVR. This study aimed to investigate the clinical as well as cost outcomes associated with conscious sedation in comparison to general anesthesia in TAVR...
2017: PloS One
https://www.readbyqxmd.com/read/28342738/american-brachytherapy-society-consensus-statement-for-soft-tissue-sarcoma-brachytherapy
#3
A O Naghavi, D C Fernandez, N Mesko, A Juloori, A Martinez, J G Scott, C Shah, L B Harrison
PURPOSE: Radiation therapy represents an essential treatment option in the management of soft tissue sarcomas (STS). Brachytherapy represents an important subset of radiation therapy techniques used for STS, with evolving indications and applications. Therefore, the purpose of this guideline was to update clinicians regarding the data surrounding brachytherapy (BT) and provide recommendations for the utilization of BT in patients with STS. METHODS AND MATERIALS: Members of the American Brachytherapy Society with expertise in STS, and STS BT in particular, created an updated guideline for the use of BT in STS based on a literature review and clinical experience...
March 22, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28265967/acc-aats-aha-ase-asnc-scai-scct-sts-2016-appropriate-use-criteria-for-coronary-revascularization-in-patients-with-acute-coronary-syndromes-a-report-of-the-american-college-of-cardiology-appropriate-use-criteria-task-force-american-association-for-thoracic-surgery
#4
Manesh R Patel, John H Calhoon, Gregory J Dehmer, James Aaron Grantham, Thomas M Maddox, David J Maron, Peter K Smith
The American College of Cardiology, Society for Cardiovascular Angiography and Interventions, Society of Thoracic Surgeons, and American Association for Thoracic Surgery, along with key specialty and subspecialty societies, have completed a 2-part revision of the appropriate use criteria (AUC) for coronary revascularization. In prior coronary revascularization AUC documents, indications for revascularization in acute coronary syndromes (ACS) and stable ischemic heart disease were combined into 1 document. To address the expanding clinical indications for coronary revascularization, and in an effort to align the subject matter with the most current American College of Cardiology/American Heart Association guidelines, the new AUC for coronary artery revascularization were separated into 2 documents addressing ACS and stable ischemic heart disease individually...
March 6, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28158190/survival-impact-of-centralization-and-clinical-guidelines-for-soft-tissue-sarcoma-a-prospective-and-exhaustive-population-based-cohort
#5
Olfa Derbel, Pierre Etienne Heudel, Claire Cropet, Pierre Meeus, Gualter Vaz, Pierre Biron, Philippe Cassier, Anne-Valérie Decouvelaere, Dominique Ranchere-Vince, Olivier Collard, Eric De Laroche, Philippe Thiesse, Fadila Farsi, Dominic Cellier, François-Noel Gilly, Jean-Yves Blay, Isabelle Ray-Coquard
PURPOSE: The outcome of sarcoma has been suggested in retrospective and non-exhaustive studies to be better through management by a multidisciplinary team of experts and adherence to clinical practice guidelines (CPGs). The aim of this prospective and exhaustive population based study was to confirm the impact of adherence to CPGs on survival in patients with localized sarcoma. EXPERIMENTAL DESIGN: Between 2005 and 2007, all evaluable adult patients with a newly diagnosis of localized sarcoma located in Rhone Alpes region (n = 634), including 472 cases of soft-tissue sarcoma (STS), were enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28144906/guidelines-in-review-2016-acc-aats-aha-asnc-scai-scct-sts-appropriate-use-criteria-for-coronary-revascularization-in-patients-with-acute-coronary-syndromes
#6
REVIEW
Samuel K McElwee, Fadi G Hage
No abstract text is available yet for this article.
January 31, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/28027730/vancomycin-paste-does-not-reduce-the-incidence-of-deep-sternal-wound-infection-after-cardiac-operations
#7
COMPARATIVE STUDY
Heather L Lander, Julius I Ejiofor, Siobhan McGurk, Kaneko Tsuyoshi, Prem Shekar, Simon C Body
BACKGROUND: Deep sternal wound infection (DSWI) is a devastating complication that increases morbidity and death in cardiac surgical patients. Vancomycin is often administered intravenously for antibiotic prophylaxis in cardiac operations. Many cardiac surgeons also apply vancomycin paste topically to the sternal edges. We examined the effect of vancomycin paste on the incidence of DSWI in patients undergoing elective cardiac operations. METHODS: We retrospectively reviewed the medical records of all patients from 2003 to 2015 who underwent coronary artery bypass grafting, valve, or combined coronary artery bypass grafting and valve operations at a single institution...
February 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27891213/uk-guidelines-for-the-management-of-soft-tissue-sarcomas
#8
REVIEW
Adam Dangoor, Beatrice Seddon, Craig Gerrand, Robert Grimer, Jeremy Whelan, Ian Judson
Soft tissue sarcomas (STS) are rare tumours arising in mesenchymal tissues, and can occur almost anywhere in the body. Their rarity, and the heterogeneity of subtype and location means that developing evidence-based guidelines is complicated by the limitations of the data available. However, this makes it more important that STS are managed by teams, expert in such cases, to ensure consistent and optimal treatment, as well as recruitment to clinical trials, and the ongoing accumulation of further data and knowledge...
2016: Clinical Sarcoma Research
https://www.readbyqxmd.com/read/27849967/326-characterizing-cardiac-arrest-in-pediatric-cardiac-surgery-using-sts-chsd-and-utstein-guidelines
#9
Punkaj Gupta, Andrew Wilcox, Jeffrey Gossett, Mallikarjuna Rao Rettiganti
No abstract text is available yet for this article.
December 2016: Critical Care Medicine
https://www.readbyqxmd.com/read/27732925/echocardiographic-pulmonary-hypertension-probability-is-associated-with-clinical-outcomes-after-transcatheter-aortic-valve-implantation
#10
V J Nijenhuis, M P Huitema, V M M Vorselaars, M J Swaans, T de Kroon, J A S van der Heyden, B J W M Rensing, R Heijmen, J M Ten Berg, M C Post
AIMS: Pulmonary hypertension (PH) is associated with mortality after transcatheter aortic valve implantation (TAVI). However, diagnosis based on tricuspid regurgitant velocity (TRV) is often inaccurate and unreliable. The updated PH guidelines introduced a PH probability grading implementing additional PH signs on transthoracic echocardiography (TTE), from which we aimed to analyse its effects on clinical outcomes in patients undergoing TAVI. METHODS AND RESULTS: We included 591 consecutive patients (mean age 80...
December 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27687052/meta-analysis-comparing-established-risk-prediction-models-euroscore-ii-sts-score-and-acef-score-for-perioperative-mortality-during-cardiac-surgery
#11
REVIEW
Patrick G Sullivan, Joshua D Wallach, John P A Ioannidis
A wide variety of multivariable risk models have been developed to predict mortality in the setting of cardiac surgery; however, the relative utility of these models is unknown. This study investigated the literature related to comparisons made between established risk prediction models for perioperative mortality used in the setting of cardiac surgery. A systematic review was conducted to capture studies in cardiac surgery comparing the relative performance of at least 2 prediction models cited in recent guidelines (European System for Cardiac Operative Risk Evaluation [EuroSCORE II], Society for Thoracic Surgeons 2008 Cardiac Surgery Risk Models [STS] score, and Age, Creatinine, Ejection Fraction [ACEF] score) for the outcomes of 1-month or inhospital mortality...
November 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27664427/is-the-ross-procedure-a-riskier-operation-perioperative-outcome-comparison-with-mechanical-aortic-valve-replacement-in-a-propensity-matched-cohort
#12
Ismail Bouhout, Pierre-Emmanuel Noly, Aly Ghoneim, Louis-Mathieu Stevens, Raymond Cartier, Nancy Poirier, Denis Bouchard, Philippe Demers, Ismail El-Hamamsy
OBJECTIVES: The aim of this study was to compare perioperative outcomes in young adults following isolated Ross procedure versus mechanical aortic valve replacement (AVR) in a high-volume centre. METHODS: From 2007 to 2015, 337 elective isolated mechanical AVRs and 137 Ross procedures were performed in young adults (<65 years) at our centre. Using a 1:1 propensity score match analysis, 140 patients were included in the study (n = 70 in each group). Perioperative outcomes were defined using STS guidelines...
September 23, 2016: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/27646968/emerging-azithromycin-resistance-among-the-neisseria-gonorrhoeae-strains-isolated-in-hungary
#13
Alexandra Brunner, Eva Nemes-Nikodem, Csaba Jeney, Dora Szabo, Marta Marschalko, Sarolta Karpati, Eszter Ostorhazi
BACKGROUND: In the 1990s, azithromycin became the drug of choice for many infectious diseases but emerging resistance to the drug has only been reported in the last decade. In the last 5 years, the National Neisseria gonorrhoeae Reference Laboratory of Hungary (NNGRLH) has also observed an increased number of N. gonorrhoeae strains resistant to azithromycin. The aim of this study was to determine the most frequent sequence types (ST) of N. gonorrhoeae related to elevated levels of azithromycin MIC (minimal inhibitory concentration)...
September 20, 2016: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/27561402/public-health-research-and-scheduled-tribes-an-ethical-lens
#15
Katia S Mohindra
In this commentary, it is argued that greater attention paid to ethical considerations related to doing Public Health Research with Scheduled Tribes (STs) should be prioritized. Given the high levels of health needs among STs as well as their high levels of deprivation, cultural oppression, and impingement on their rights, there is a need to revisit our research practices to contribute to better health and overall empowerment. Specific strategies that could be integrated into research practice are offered. The paper concludes with a call for the development of national guidelines for Public Health Research with STs...
July 2016: Indian Journal of Public Health
https://www.readbyqxmd.com/read/27502605/accreditation-for-centers-of-sarcoma-surgery
#16
Sergio Sandrucci, Annalisa Trama, Vittorio Quagliuolo, Alessandro Gronchi
Soft-tissue sarcomas (STS) are a heterogeneous group of neoplasms which may be subclassified into over 70 specific histologies and may be distributed throughout the body. Approximately one-half arises in the extremities and one-third arises in the abdomen, pelvis, and retroperitoneum. The diversity and rarity of sarcomas combined with the quite large number of affected patients are factors which underline of the importance of networking in diagnosis, therapy, and research dealing with rare cancers. The expertise of the treating center is one of the most significant factors affecting survival in STS...
August 8, 2016: Updates in Surgery
https://www.readbyqxmd.com/read/27484846/hairy-matters-mtdna-quantity-and-sequence-variation-along-and-among-human-head-hairs
#17
Stijn Desmyter, Martin Bodner, Gabriela Huber, Sophie Dognaux, Cordula Berger, Fabrice Noël, Walther Parson
Hairs from the same donor have been found to differ in mtDNA sequence within and among themselves and from other tissues, which impacts interpretation of results obtained in a forensic setting. However, little is known on the magnitude of this phenomenon and published data on systematic studies are scarce. We addressed this issue by generating mtDNA control region (CR) profiles of >450 hair fragments from 21 donors by Sanger-type sequencing (STS). To mirror forensic scenarios, we compared hair haplotypes from the same donors to each other, to the corresponding buccal swab reference haplotypes and analyzed several fragments of individual hairs...
July 25, 2016: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/27354068/comparison-of-contemporary-preoperative-risk-models-at-predicting-acute-kidney-injury-after-isolated-coronary-artery-bypass-grafting-a-retrospective-cohort-study
#18
Shao-Wei Chen, Chih-Hsiang Chang, Pei-Chun Fan, Yung-Chang Chen, Pao-Hsien Chu, Tien-Hsing Chen, Victor Chien-Chia Wu, Su-Wei Chang, Pyng-Jing Lin, Feng-Chun Tsai
OBJECTIVES: Acute kidney injury (AKI) after coronary artery bypass grafting (CABG) is associated with short-term and long-term adverse outcomes. The European System for Cardiac Operative Risk Evaluation (EuroSCORE), EuroSCORE II, the Society of Thoracic Surgeons (STS) score and Age, Creatinine and Ejection Fraction (ACEF) score, have been widely used for predicting the operative risk of cardiac surgery. The aim of this study is to investigate the discriminant ability among current available models in predicting postoperative AKI...
2016: BMJ Open
https://www.readbyqxmd.com/read/27283169/soft-tissue-sarcoma-version-2-2016-nccn-clinical-practice-guidelines-in-oncology
#19
Margaret von Mehren, R Lor Randall, Robert S Benjamin, Sarah Boles, Marilyn M Bui, Ernest U Conrad, Kristen N Ganjoo, Suzanne George, Ricardo J Gonzalez, Martin J Heslin, John M Kane, Henry Koon, Joel Mayerson, Martin McCarter, Sean V McGarry, Christian Meyer, Richard J O'Donnell, Alberto S Pappo, I Benjamin Paz, Ivy A Petersen, John D Pfeifer, Richard F Riedel, Scott Schuetze, Karen D Schupak, Herbert S Schwartz, William D Tap, Jeffrey D Wayne, Mary Anne Bergman, Jillian Scavone
Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and treatment of patients with STS requires a multidisciplinary team with demonstrated expertise in the management of these tumors. The complete NCCN Guidelines for Soft Tissue Sarcoma (available at NCCN.org) provide recommendations for the diagnosis, evaluation, and treatment of extremity/superficial trunk/head and neck STS, as well as intra-abdominal/retroperitoneal STS, gastrointestinal stromal tumor, desmoid tumors, and rhabdomyosarcoma...
June 2016: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/27280420/evaluation-of-an-optimal-epidemiological-typing-scheme-for-legionella-pneumophila-with-whole-genome-sequence-data-using-validation-guidelines
#20
Sophia David, Massimo Mentasti, Rediat Tewolde, Martin Aslett, Simon R Harris, Baharak Afshar, Anthony Underwood, Norman K Fry, Julian Parkhill, Timothy G Harrison
Sequence-based typing (SBT), analogous to multilocus sequence typing (MLST), is the current "gold standard" typing method for investigation of legionellosis outbreaks caused by Legionella pneumophila However, as common sequence types (STs) cause many infections, some investigations remain unresolved. In this study, various whole-genome sequencing (WGS)-based methods were evaluated according to published guidelines, including (i) a single nucleotide polymorphism (SNP)-based method, (ii) extended MLST using different numbers of genes, (iii) determination of gene presence or absence, and (iv) a kmer-based method...
August 2016: Journal of Clinical Microbiology
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