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https://www.readbyqxmd.com/read/28657184/the-use-of-supplements-and-performance-and-image-enhancing-drugs-in-fitness-settings-a-exploratory-cross-sectional-investigation-in-the-united-kingdom
#1
Roisin Mooney, Pierluigi Simonato, Risha Ruparelia, Andres Roman-Urrestarazu, Giovanni Martinotti, Ornella Corazza
OBJECTIVE: The strive for perfection is prevalent in the fitness industry. This study aimed to explore the use of products to enhance performance alongside exposure to exercise addiction, appearance anxiety and self-esteem in fitness settings. METHODS: An online survey was prepared and piloted before wider dissemination in fitness clubs via snowballing and selected mailing lists. A list of commonly used products, including Performance and Image Enhancing Drugs (PIEDs) was provided...
May 2017: Human Psychopharmacology
https://www.readbyqxmd.com/read/28457658/pilot-scale-production-of-poly-3-hydroxybutyrate-co-4-hydroxybutyrate-biopolymers-with-high-molecular-weight-and-elastomeric-properties
#2
Kai-Hee Huong, Mat Junoh Azuraini, Nursolehah Abdul Aziz, Al-Ashraf Abdullah Amirul
Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [(P(3HB-co-4HB)] copolymer receives attention as next generation biomaterial in medical application. However, the exploitation of the copolymer is still constrained since such copolymer has not yet successfully been performed in industrial scale production. In this work, we intended to establish pilot production system of the copolymer retaining the copolymer quality which has recently discovered to have novel characteristic from lab scale fermentation. An increase of agitation speed has significantly improved the copolymer accumulation efficiency by minimizing the utilization of substrates towards cell growth components...
July 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28343243/fusarium-species-a-promising-tool-box-for-industrial-biotechnology
#3
REVIEW
Marina Gabriel Pessôa, Bruno Nicolau Paulino, Mario Cezar Rodrigues Mano, Iramaia Angélica Neri-Numa, Gustavo Molina, Glaucia Maria Pastore
Global demand for biotechnological products has increased steadily over the years. Thus, need for optimized processes and reduced costs appear as a key factor in the success of this market. A process tool of high importance is the direct or indirect use of enzymes to catalyze the generation of various substances. Also, obtaining aromas and pigments from natural sources has becoming priority in cosmetic and food industries in order to supply the demand from consumers to substitute synthetic compounds, especially when by-products can be used as starting material for this purpose...
May 2017: Applied Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28277879/crude-4-methylcyclohexanemethanol-mchm-did-not-cause-skin-irritation-in-humans-in-48-h-patch-test
#4
Andrew D Monnot, Rachel M Novick, Dennis J Paustenbach
Crude 4-methylcyclohexanemethanol (MCHM) is an industrial chemical used to wash and clean coal. On January 9th, 2014 approximately 10,000 gallons of a mixture containing crude MCHM were released into the Elk River near Charleston, West Virginia, contaminating the local water supply. Following the spill, residents reported numerous health complaints, and sought medical attention for ailments including rashes and itching. The relationship between the complaints and the spill were unknown, as such symptoms are reported frequently in the background...
March 13, 2017: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/28230450/characteristics-and-medication-use-of-psoriasis-patients-who-may-or-may-not-qualify-for-randomized-controlled-trials
#5
William Malatestinic, Beth Nordstrom, Jashin J Wu, Orin Goldblum, Kathleen Solotkin, Chen-Yen Lin, Kristin Kistler, Kathy Fraeman, Joseph Johnston, Lcdr Lesley Hawley, Nicholas Sicignano, Andre Araujo
BACKGROUND: Clinical trials impose exclusion criteria that may limit the generalizability of results. OBJECTIVES: To (a) determine the percentage of real-world patients who would qualify for psoriasis randomized controlled trials; (b) ascertain differences between moderate-to-severe psoriasis patients who would be eligible, ineligible, or potentially eligible for clinical trials; and (c) compare their biologic treatment patterns. METHODS: Moderate-to-severe psoriasis patients were identified from the U...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28220717/merger-acquisition-and-capital-expenditure-in-health-care
#6
Wenjing Ouyang, Peter E Hilsenrath
Investment, especially through merger and acquisition (M&A), is a leading topic of concern among health care managers. In addition, the implications of this activity for organization and market concentration are of great interest to policy makers. Using a sample of 2256 firm-year observations in the health care industry during the period from 1985 to 2011, this article provides novel evidence that managers learn from financial markets in making capital expenditure (CAPEX) and M&A investment decisions. Within the industry, managers in the Drugs subsector are most likely to do so, whereas managers in the Medical Equipment and Supplies are least likely to do so...
January 2017: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/28110669/in-vitro-screening-and-in-silico-validation-revealed-key-microbes-for-higher-production-of-significant-therapeutic-enzyme-l-asparaginase
#7
Archana Vimal, Awanish Kumar
l-asparaginase is an enzyme of medical prominence and reputable as a chemotherapeutic agent. It also has immense potential to cure autoimmune and infectious diseases. The vast application of this enzyme in healthcare sector increases its market demand. However, presently the huge market demand is not achieved completely. This serves the basis to explore better producer microbial strains to bridge the gap between huge demand and supply of this therapeutic enzyme. The present study deals with the successful screening of potent microorganisms producing l-asparaginase...
March 2017: Enzyme and Microbial Technology
https://www.readbyqxmd.com/read/28027167/meeting-the-needs-of-the-nation-for-radiation-protection-summary-of-the-52nd-annual-meeting-of-the-national-council-on-radiation-protection-and-measurements
#8
Richard E Toohey
The 52nd Annual Meeting of the National Council on Radiation Protection and Measurements (NCRP) was held in Bethesda, MD, 11-12 April 2016, on the topic of "Meeting National Needs for Radiation Protection." This meeting was an outgrowth of the NCRP initiative "Where are the Radiation Professionals?" (WARP), which addresses looming shortages in professional personnel trained in the radiological disciplines, including but not limited to health physics, radiological engineering, radiobiology, radiochemistry, radioecology, radiation emergency response; and the medical disciplines of diagnostic and interventional radiology, radiation oncology, nuclear medicine, and medical physics...
February 2017: Health Physics
https://www.readbyqxmd.com/read/27891693/understanding-and-learning-from-the-diversification-of-cannabis-supply-laws
#9
Beau Kilmer, Rosalie Liccardo Pacula
BACKGROUND AND AIMS: Prohibitions on producing, distributing and selling cannabis are loosening in various jurisdictions around the world. This paper describes the diversification of cannabis supply laws and discusses the challenges to and opportunities for learning from these changes. METHODS: We document changes in cannabis supply laws that de jure legalized cannabis production for medical and/or non-medical purposes (excluding industrial hemp) in Australasia, Europe, North America and South America...
July 2017: Addiction
https://www.readbyqxmd.com/read/27872967/l-methionine-production
#10
Jihyun Shim, Yonguk Shin, Imsang Lee, So Young Kim
L-Methionine has been used in various industrial applications such as the production of feed and food additives and has been used as a raw material for medical supplies and drugs. It functions not only as an essential amino acid but also as a physiological effector, for example, by inhibiting fat accumulation and enhancing immune response. Producing methionine from fermentation is beneficial in that microorganisms can produce L-methionine selectively using eco-sustainable processes. Nevertheless, the fermentative method has not been used on an industrial scale because it is not competitive economically compared with chemical synthesis methods...
November 22, 2016: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/27844015/l-asparaginase-production-in-the-pseudomonas-pseudoalcaligenes-strain-jhs-71-isolated-from-jooshan-hot-spring
#11
Arastoo Badoei-Dalfard
L-asparaginase has lots of medical and industrial applications. Ever since L-asparaginase anti-tumor activity was first demonstrated, its production using microbial systems has attracted considerable attention owing to their cost-effective and eco-friendly nature. The aim of this study is to obtain L-asparaginase producing bacteria and determining the enzyme activity. Samples were picked up from Jooshan hot springs located in the Sirch, Kerman. The L-asparaginase producing bacteria were screened on the agar medium supplied with L-asparagine and phenol red indicator dye (pH-7...
March 2016: Molecular Biology Research Communications
https://www.readbyqxmd.com/read/27808023/searching-for-best-direction-in-healthcare-distilling-opportunities-priorities-and-responsibilities
#12
Terrence Montague, Amédé Gogovor, Lucas Marshall, Bonnie Cochrane, Sara Ahmed, Emily Torr, John Aylen, Joanna Nemis-White
Canada's health and its care are evolving. Evidence from serial Health Care in Canada surveys of the public and health professionals over the last two decades reveal a persistent sense of care quality, despite an aging population, decreasing levels of good and excellent health, increasing prevalence of chronic illnesses; and sub-optimal access to timely and patient-centred care. Stakeholders are, however, somewhat pessimistic and many sense complete rebuilding, or major changes, may be necessary. To improve access, the primary health concern of all Canadians - increasing medical and nursing school enrolment, and requiring professionals to work in teams - have attracted increasingly high support from both the public and professionals...
2016: Healthcare Quarterly
https://www.readbyqxmd.com/read/27635235/recent-advances-in-synthetic-biosafety
#13
REVIEW
Anna J Simon, Andrew D Ellington
Synthetically engineered organisms hold promise for a broad range of medical, environmental, and industrial applications. Organisms can potentially be designed, for example, for the inexpensive and environmentally benign synthesis of pharmaceuticals and industrial chemicals, for the cleanup of environmental pollutants, and potentially even for biomedical applications such as the targeting of specific diseases or tissues. However, the use of synthetically engineered organisms comes with several reasonable safety concerns, one of which is that the organisms or their genes could escape their intended habitats and cause environmental disruption...
2016: F1000Research
https://www.readbyqxmd.com/read/27555801/medicine-reclassification-processes-and-regulations-for-proper-use-of-over-the-counter-self-care-medicines-in-japan
#14
Kaori Nomura, Yuki Kitagawa, Yasukatsu Yuda, Hiromi Takano-Ohmuro
OBJECTIVES: Japan has actively reclassified substances ranging from prescription drugs to over-the-counter (OTC) drugs in recent years. The sale of most OTC drugs was deregulated several times and pharmacists' supervision was deemed no longer mandatory. Japan established a new OTC evaluation system in 2015 to hear opinions from various stakeholders regarding medicine types to be reclassified. This study aimed to examine the new framework to identify candidate substances for reclassification...
2016: Risk Management and Healthcare Policy
https://www.readbyqxmd.com/read/27547162/three-myths-about-dietary-supplements-%C3%A2-and-how-knowing-the-right-answers-is-good-for-your-integrative-medicine-practice
#15
Loren Israelsen, Frank Lampe
The use of safe and beneficial dietary supplements remains an important part of your patients' healthy lifestyle-and supplements are likely an important part of your integrative medicine practice. Although issues surrounding potency, ingredient identification, adulteration, and the enforcement of existing laws are legitimate concerns for medical professionals and consumers, the responsible industry is actively working to raise quality standards for its products through a number of self-regulatory measures. These include education about and adoption of additional quality assurance initiatives, such as GMPs for botanical ingredients; better supply-chain management; adoption of improved identification and testing methodologies; an industry-wide product registry; the use of accredited third-party certifications and seals; and initiatives to promote widespread membership in the industry's trade associations, which is a reliable indicator of a company's support of and adherence to strict quality guidelines...
June 2016: Integrative Medicine
https://www.readbyqxmd.com/read/27529446/-counterfeit-medicines-in-internet-and-the-fakeshare-european-project-experiences-and-activities-in-spain
#16
Daniel Catalán-Matamoros, Nuria González-Ochando, Henar Pecharroman-Arribas, Ana Fernández-Muelas, Stella Sandra Bentolila-Benchimol, Manuel IbarraLorente
The illicit trafficking of medicines over the Internet is a growing problem that affects public health. Since 2013, the Spanish Agency of Medicines and Medical Devices (AEMPS) participates in the European project Fakeshare, co-funded by the European Commission and coordinated by the Italian Medicines Agency (Agenzia Italiana del Farmaco, AIFA). This project aims to coordinate initiatives against the illegal supply of medicines, including from purchases through websites engaged in illegal activity, to thefts and other diversions of medicines to the illicit trafficking...
August 16, 2016: Revista Española de Salud Pública
https://www.readbyqxmd.com/read/27497859/-whether-something-cool-is-good-enough-the-role-of-evidence-sales-representatives-and-nurses-expertise-in-hospital-purchasing-decisions
#17
Quinn Grundy
The emphasis on "value" within healthcare institutions has achieved unprecedented priority, particularly around the purchase of medical products and equipment. Health systems and institutions are implementing formal decision-making processes involving clinicians and supply chain professionals to rationalize purchasing and promote cost-effective investment. One particular form of this process is the "Value Analysis" process. Drawing from fieldwork (100 h), interviews (n = 51) and focus groups (n = 4) conducted from January 2012 to October 2014 at 4 acute care hospitals in the western United States, I analyze the ways that committee members constructed and evaluated a case for a product's value...
September 2016: Social Science & Medicine
https://www.readbyqxmd.com/read/27486651/drug-packaging-in-2015-risky-industry-choices-and-lax-regulation
#18
(no author information available yet)
Prescrire examined the packaging quality of 240 drugs in 2015. No new advances were identified, but drug packaging continues to expose patients to a variety of dangers. Some past advances persist: for example, INNs are often more legible, and recent patient leaflets tend to be clearer and more informative. But these measures are not applied to all drugs, and are rarely applied retroactively to older drugs. The overall picture in 2015 is that many drugs are difficult to identify, risky or downright dangerous to prepare, or supplied with patient leaflets that fail to correctly inform patients about their medication...
June 2016: Prescrire International
https://www.readbyqxmd.com/read/27283243/disruptive-innovation-in-community-pharmacy-impact-of-automation-on-the-pharmacist-workforce
#19
Jean Spinks, John Jackson, Carl M Kirkpatrick, Amanda J Wheeler
Pharmacy workforce planning has been relatively static for many decades. However, like all industries, health care is exposed to potentially disruptive technological changes. Automated dispensing systems have been available to pharmacy for over a decade and have been applied to a range of repetitive technical processes which are at risk of error, including record keeping, item selection, labeling and dose packing. To date, most applications of this technology have been at the local level, such as hospital pharmacies or single-site community pharmacies...
May 14, 2016: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/27280706/environmental-impacts-of-the-u-s-health-care-system-and-effects-on-public-health
#20
Matthew J Eckelman, Jodi Sherman
The U.S. health care sector is highly interconnected with industrial activities that emit much of the nation's pollution to air, water, and soils. We estimate emissions directly and indirectly attributable to the health care sector, and potential harmful effects on public health. Negative environmental and public health outcomes were estimated through economic input-output life cycle assessment (EIOLCA) modeling using National Health Expenditures (NHE) for the decade 2003-2013 and compared to national totals...
2016: PloS One
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