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https://www.readbyqxmd.com/read/28088416/space-allowance-influences-individually-housed-holstein-bull-calf-innate-immune-measures-and-standing-behaviors-after-castration-at-3-weeks-of-age
#1
M S Calvo-Lorenzo, L E Hulbert, M A Ballou, A L Fowler, Y Luo, K C Klasing, F M Mitloehner
Dairy calves in the Southwest regions of the United States are typically raised individually in wooden hutches with 1.23 m(2) of space. The objective of the study was to determine if increased space allowance in wooden hutches influences measures of innate immunity and behaviors of Holstein bull calves pre- and postcastration. Calves were randomly assigned at 4 d of age to conventional (CONV; 1.23 m(2) of space; n = 18), moderate (MOD; 1.85 m(2) space; n = 17), or maximized space allowance (MAX; 3.71 m(2) space; n = 19) in hutches...
January 11, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28080905/plasma-protein-electrophoresis-and-select-acute-phase-proteins-in-healthy-bonnethead-sharks-sphyrna-tiburo-under-managed-care
#2
Michael W Hyatt, Cara L Field, Tonya M Clauss, Kristopher L Arheart, Carolyn Cray
Preventative health care of elasmobranchs is an important but understudied field of aquatic veterinary medicine. Evaluation of inflammation through the acute phase response is a valuable tool in health assessments. To better assess the health of bonnethead sharks ( Sphyrna tiburo ) under managed care, normal reference intervals of protein electrophoresis (EPH) and the acute phase proteins, C-reactive protein (CRP) and haptoglobin (HP), were established. Blood was collected from wild caught, captive raised bonnethead sharks housed at public aquaria...
December 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28079528/assessing-the-evolution-of-redundancy-synergy-of-spontaneous-variability-regulation-with-age
#3
Alberto Porta, Vlasta Bari, Beatrice De Maria, Natália Maria Perseguini, Juliana Milan, Patricia Rehder-Santos, Vinícius Minatel, Anielle Takahashi, Aparecida Catai
We exploited a model-based Wiener-Granger causality method in the information domain for the evaluation of the transfer entropy (TE) and interaction TE (ITE), the latter taken as a measure of the net balance between redundancy and synergy, to describe the interactions between the spontaneous variability of heart period (HP) and systolic arterial pressure (SAP) and the effect of respiration (R) on both variables. Cardiac control was typified via the genuine TE from SAP to HP, that from R to HP, and the ITE from SAP and R to HP, while vascular control was characterized via the genuine TE from HP to SAP, that from R to SAP, and the ITE from HP and R to SAP...
January 12, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28079397/mixed-compared-with-single-source-proteins-in-high-protein-diets-affect-kidney-structure-and-function-differentially-in-obese-fa-fa-zucker-rats
#4
Jessay G Devassy, Jennifer L Wojcik, Naser H M Ibrahim, Peter Zahradka, Carla G Taylor, Harold M Aukema
Questions remain regarding the potential negative effects of dietary high protein (HP) on kidney health, particularly in the context of obesity in which the risk for renal disease is already increased. To examine whether some of the variability in HP effects on kidney health may be due to source of protein, obese fa/fa Zucker rats were given HP (35% of energy from protein) diets containing either casein, soy protein, or a mixed source of animal and plant proteins for 12 weeks. Control lean and obese rats were given diets containing casein at normal protein (15% of energy from protein) levels...
October 6, 2016: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/28079268/renoprotective-effect-of-hypericum-perforatum-against-diabetic-nephropathy-in-rats-insights-in-the-underlying-mechanisms
#5
Dalia M Abd El Motteleb, Dalia I Abd El Aleem
Oxidative stress and inflammation play a key role in the initiation and progression of diabetic nephropathy (DN). The present study aimed to investigate the possible protective effect of hypericum perforatum (HP) against DN. Rats were allocated into six groups; control: received normal saline, diabetic untreated (DM): received single dose of streptozotocin (STZ) after injection of nicotinamide (NA), gliclazide: received STZ,NA+ gliclazide (10mg/kg), DM+HP50, DM+HP100, DM+HP200:received STZ,NA and HP 50, 100, 200 mg/kg respectively...
January 12, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28078126/gastrointestinal-lymphoma-in-western-algeria-pattern-of-distribution-and-histological-subtypes-retrospective-study
#6
Soumia Zeggai, Noria Harir, Abdenacer Tou, Miloud Medjamia, Khaira Guenaoui
BACKGROUND: Primary gastrointestinal (GI) lymphomas (GIL) are uncommon diseases that can involve the whole GI tract. Considerable variation exists in the literature with respect to incidence of the various histological subtypes and sites of involvement. This study was undertaken to establish the anatomic distribution, histological subtypes and sites of GI lymphomas of patients from Western Algeria. METHODS: The case records of 58 consecutive patients with GIL diagnosed at the Pathologies Departments of Algerian west region (the Military Hospital of Oran city and the Central University Hospital of Sidi Bel Abbes city) from January 2006 to December 2013 were retrospectively evaluated for epidemiology and histopathology report...
December 2016: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28077732/high-protein-and-high-dietary-fiber-breakfasts-result-in-equal-feelings-of-fullness-and-better-diet-quality-in-low-income-preschoolers-compared-with-their-usual-breakfast
#7
Sibylle Kranz, Mary Brauchla, Wayne W Campbell, Rickard D Mattes, Amy J Schwichtenberg
BACKGROUND: In the United States, 17% of children are currently obese. Increasing feelings of fullness may prevent excessive energy intake, lead to better diet quality, and promote long-term maintenance of healthy weight. OBJECTIVE: The purpose of this study was to develop a fullness-rating tool (aim 1) and to determine whether a high-protein (HP), high-fiber (HF), and combined HP and HF (HPHF) breakfast increases preschoolers' feelings of fullness before (pre) and after (post) breakfast and pre-lunch, as well as their diet quality, as measured by using a composite diet quality assessment tool, the Revised Children's Diet Quality Index (aim 2)...
January 11, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28077268/development-of-high-resolution-3d-hyperpolarized-carbon-13-mr-molecular-imaging-techniques
#8
Eugene Milshteyn, Cornelius von Morze, Galen D Reed, Hong Shang, Peter J Shin, Zihan Zhu, Hsin-Yu Chen, Robert Bok, Andrei Goga, John Kurhanewicz, Peder E Z Larson, Daniel B Vigneron
The goal of this project was to develop and apply techniques for T2 mapping and 3D high resolution (1.5 mm isotropic; 0.003 cm(3)) (13)C imaging of hyperpolarized (HP) probes [1-(13)C]lactate, [1-(13)C]pyruvate, [2-(13)C]pyruvate, and [(13)C,(15)N2]urea in vivo. A specialized 2D bSSFP sequence was implemented on a clinical 3T scanner and used to obtain the first high resolution T2 maps of these different hyperpolarized compounds in both rats and tumor-bearing mice. These maps were first used to optimize timings for highest SNR for single time-point 3D bSSFP acquisitions with a 1...
January 7, 2017: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/28072936/haptoglobin-and-free-haemoglobin-during-cardiac-surgery-is-there-a-link-to-acute-kidney-injury
#9
A J Wetz, E M Richardt, H Schotola, M Bauer, A Bräuer
Acute kidney injury (AKI) is frequently observed after cardiac surgery (CS) with cardiopulmonary bypass (CPB). Multiple mechanisms underlie this phenomenon, including CPB-dependent haemolysis. Haemoglobin is released during haemolysis, and free haemoglobin (frHb) causes tubular cell injury after exceeding the binding capacity of haptoglobin (Hp). The objective of this study was to investigate the influence of perioperative changes in frHb and Hp levels on the incidence of CS-associated (CSA) AKI. After receiving local ethics committee approval and obtaining informed consent from our patients, we analysed the data pertaining to 154 patients undergoing CPB surgery...
January 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/28072881/reciprocal-symbiont-sharing-in-the-lodging-mutualism-between-walking-corals-and-sipunculans
#10
Momoko Igawa, Hiroki Hata, Makoto Kato
Solitary scleractinian corals of the genera Heterocyathus and Heteropsammia inhabit soft marine bottoms without attaching to hard substrata. The corallums of these genera contain a coiled cavity inhabited by a sipunculan that roams the seafloor, carrying the host coral with it. The coral serves as a sturdy shelter that protects the sipunculan from possible predators. At the same time, the sipunculan maintains the coral in an upright position on the soft bottom. This coral-sipunculan association is unique because two phylogenetically distant coral genera have developed convergent associations with sipunculans...
2017: PloS One
https://www.readbyqxmd.com/read/28068579/changes-in-fatty-acid-metabolism-induced-by-varied-micro-supplementation-with-zinc-in-snails-helix-pomatia-gastropoda-pulmonata
#11
Danuta Kowalczyk-Pecka, Stanisław Pecka, Edyta Kowalczuk-Vasilev
We analyzed the changes in the profile of fatty acids (FA) in the foot tissues and hepatopancreas (HP) of snails Helix pomatia exposed to five microdoses of zinc (0.1, 0.25, 0.5, 0.75, or 1mg/l) administered in the form of a pure salt solution and in the form of EDTA and lysine chelates. Selection from a pool of 56 fatty acids analyzed in snail tissues yielded a set of 12 biomarker acids undergoing significant changes in contact with toxic substances. The selection criteria included the greatest percentage among the FA profile and their significant role in physiological processes...
January 6, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28063587/indirect-chiral-separation-of-8-novel-amphetamine-derivatives-as-potential-new-psychoactive-compounds-by-gc-ms-and-hplc
#12
Jennifer A Weiß, Kian Kadkhodaei, Martin G Schmid
Amphetamine and its derivatives gained high popularity on the illegal drug market. In the last few years, a lot of new psychoactive compounds structurally related to amphetamine, such as 4-fluoroamphetamine and 4-fluoromethamphetamine swamped the drug market. They were designed to circumvent prohibition of amphetamine and N-methylamphetamine and are distributed via the Internet. Often, a halogen atom is introduced into the phenyl ring of amphetamine to turn the illegal amphetamine legal. Since amphetamines possess a chiral centre, two enantiomers are available, which might differ in activity...
January 2017: Science & Justice: Journal of the Forensic Science Society
https://www.readbyqxmd.com/read/28063479/positive-immunomodulatory-effects-of-heterologous-dna-vaccine-modified-live-vaccine-prime-boost-immunization-against-the-highly-pathogenic-prrsv-infection
#13
Chaitawat Sirisereewan, Teerawut Nedumpun, Sawang Kesdangsakonwut, Yonlayong Woonwong, Roongtham Kedkovid, Jirapat Arunorat, Roongroje Thanawongnuwech, Sanipa Suradhat
Porcine reproductive and respiratory syndrome virus (PRRSV) infection is one of the most important swine pathogens, and causes a major economic impact worldwide. Recently, a new variant type 2 PRRSV, highly pathogenic PRRSV (HP-PRRSV) has emerged and continued to circulate in Southeast Asia region. Currently, commercially available PRRSV vaccines, modified live PRRS vaccines (MLV) are not able to provide complete protection against HP-PRRSV and been reported to induce negative immunomodulatory effects. Interestingly, a novel DNA vaccine was developed and successfully used to improve PRRSV-specific immune responses following MLV vaccination...
January 2017: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/28057901/genetic-diversity-and-phylogenetic-analysis-of-porcine-reproductive-and-respiratory-syndrome-virus-in-southern-china-from-2007-to-2014
#14
Qiwen Wu, Zhili Li, Guanqun Zhang, Jianqiang Niu, Xiduo Zeng, Baoli Sun, Jingyun Ma
Porcine reproductive and respiratory syndrome virus (PRRSV) has a high degree of genetic variation. Here, we characterized the genetic variation and evolutionary relationships among circulating PRRSV strains in Southern China. In this study, we analyzed 29 NSP2 strains and 150 ORF5 strains from clinical samples collected in Southern China during 2007-2014. The alignment results showed that the nucleotide identities of the two genes among these strains were 80.5-99.7% and 80.9-100%, respectively. Phylogenetic analysis based on NSP2 gene showed that high pathogenic PRRSV were still the dominant virus in Southern China from 2013 to 2014...
January 4, 2017: Journal of Veterinary Science
https://www.readbyqxmd.com/read/28056333/-recommendation-for-the-prevention-and-treatment-of-non-steroidal-anti-inflammatory-drug-induced-gastrointestinal-ulcers-and-its-complications
#15
(no author information available yet)
Non-steroidal anti-inflammatory drugs (NSAIDs) are a broad class of non glucocorticoid drugs which are extensively used in anti-inflammatory, analgesic, and antipyretic therapies. However, NSAIDs may cause many side effects, most commonly in gastrointestinal(GI) tract. Cardiovascular system, kidney, liver, central nervous system and hematopoietic system are also involved. NSAID-induced GI side effects not only endanger the patients' health, increase mortality, but also greatly increase the cost of medical care...
January 1, 2017: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/28056089/helicobacter-pylori-promote-b7-h1-expression-by-suppressing-mir-152-and-mir-200b-in-gastric-cancer-cells
#16
Gengchen Xie, Wei Li, Ruidong Li, Ke Wu, Ende Zhao, Yu Zhang, Peng Zhang, Liang Shi, Di Wang, Yuping Yin, Rui Deng, Kaixiong Tao
The most common cause of gastric cancer is infection with helicobacter pylori (HP), but the associated molecular mechanism is not well understood. In the present study, we found a marked increase in the expression of B7-H1, a member of the B7 co-stimulatory family of molecules that bind to programmed death-1 (PD-1) and play a critical immunoregulatory role in the cell-mediated immune response, in HP-positive gastric cancer tissue. Infection of cultured gastric cancer cells with HP promoted B7-H1 expression and inhibited miR-152 and miR-200b expression...
2017: PloS One
https://www.readbyqxmd.com/read/28054191/central-venous-pressure-drop-after-hypovolemic-phlebotomy-is-a-strong-independent-predictor-of-intraoperative-blood-loss-during-liver-resection
#17
Andries Ryckx, Claudine Christiaens, Mathias Clarysse, Franky Vansteenkiste, Pieter Jan Steelant, Gregory Sergeant, Isabelle Parmentier, Hans Pottel, Mathieu D'Hondt
BACKGROUND: Intraoperative hypovolemic phlebotomy (HP) has been suggested to reduce central venous pressure (CVP) before hepatectomy. This study aimed to analyze the impact of CVP drop after HP on intraoperative blood loss and postoperative renal function. METHODS: A retrospective review of a prospective database including 100 consecutive patients (43 males and 57 females; mean age, 65 years; range 23-89 years) undergoing liver resection with HP was performed. The primary outcome variable was estimated blood loss (EBL), and the secondary outcome was postoperative serum creatinin (Scr)...
January 4, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28053856/a-primary-esophageal-malt-lymphoma-patient-with-helicobacter-pylori-infection-achieved-complete-remission-after-h-pylori-eradication-without-anti-lymphoma-treatment
#18
Keiichi Moriya, Hideto Tamura, Kyoko Nakamura, Masaru Hosone, Koiti Inokuchi
Primary esophageal lymphoma is an extremely rare disease. We report a 76-year-old woman with esophageal lymphoma who achieved remission after Helicobacter pylori (HP) eradication. Esophagogastroduodenoscopy (EGD) revealed a mass in the lower esophagus, and she was diagnosed with stage IE mucosa-associated lymphoid tissue (MALT) lymphoma. She rejected any anti-lymphoma treatment except for HP eradication. Follow-up EGD demonstrated the disappearance of the esophageal MALT lymphoma 2 months after HP eradication, and she remained in remission for more than 3 years...
2017: Leukemia Research Reports
https://www.readbyqxmd.com/read/28052817/spectrophotometric-assay-for-sensitive-detection-of-glycerol-dehydratase-activity-using-aldehyde-dehydrogenase
#19
Eul-Soo Park, Sunghoon Park, Jong-Shik Shin
Glycerol dehydratase (GDHt) is a pivotal enzyme for fermentative utilization of glycerol by catalyzing radical-mediated conversion of glycerol into 3-hydroxypropionaldehyde (3-HPA). Precise and sensitive monitoring of cellular GDHt activity during the fermentation process is a prerequisite for reliable metabolic analysis to afford efficient cellular engineering and process optimization. Here we report a new spectrophotometric assay for the sensitive measurement of the GDHt activity with a sub-nanomolar limit of detection (LOD)...
January 2, 2017: Journal of Bioscience and Bioengineering
https://www.readbyqxmd.com/read/28052763/development-and-evaluation-of-a-diagnostic-cytokine-release-assay-for-mycobacterium-suricattae-infection-in-meerkats-suricata-suricatta
#20
Charlene Clarke, Stuart James Patterson, Julian Ashley Drewe, Paul David van Helden, Michele Ann Miller, Sven David Charles Parsons
BACKGROUND: Sensitive diagnostic tools are necessary for the detection of Mycobacterium suricattae infection in meerkats (Suricata suricatta) in order to more clearly understand the epidemiology of tuberculosis and the ecological consequences of the disease in this species. We therefore aimed to develop a cytokine release assay to measure antigen-specific cell-mediated immune responses of meerkats. RESULTS: Enzyme-linked immunosorbent assays (ELISAs) were evaluated for the detection of interferon-gamma (IFN-γ) and IFN-γ inducible protein 10 (IP-10) in meerkat plasma...
January 4, 2017: BMC Veterinary Research
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