keyword
https://read.qxmd.com/read/38656423/predictive-role-of-systemic-immune-inflammation-index-and-neutrophil-lymphocyte-ratio-values-in-infants-with-retinopathy-of-prematurity
#1
JOURNAL ARTICLE
Oğuzhan Oruz, Mehmet Serdar Dervişoğulları, Müzeyyen Ezgi Öktem, Caner İncekaş
PURPOSE: To search the relationship between serum neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and systemic immune-inflammation index (SII) values with the development of retinopathy of prematurity (ROP) and the requirement for laser treatment. METHODS: This retrospective cohort study was carried out with 195 preterm infants between 2012 and 2023. The NLR, PLR, LMR, and SII values were calculated on both the first day and at the end of the first month after birth...
April 24, 2024: Graefe's Archive for Clinical and Experimental Ophthalmology
https://read.qxmd.com/read/38652818/histopathological-evaluation-of-bipolar-and-microneedle-radiofrequency-energy-on-the-skin-and-fat-of-the-abdominal-region-of-the-rat
#2
JOURNAL ARTICLE
Caner Gelbal, Burak Ergün Tatar, Bengi Yilmaz, Yiğit Uyanikgil, Canberk Tomruk, Mehmet Bozkurt
BACKGROUND: Radiofrequency (RF)-based devices are frequently used in plastic surgeries. In the current literature, no comparative experimental study has demonstrated the histological and immunological effects of these devices that are frequently used in the facial area. In this study, we investigated the histological and immunological effects of Bipolar RF (BodyTite) and Microneedle RF (Morpheus 8) devices in the rat abdominal region. METHODS: 24 rats were used in this study...
April 23, 2024: Plastic and Reconstructive Surgery
https://read.qxmd.com/read/38651684/trypanosomes-and-gut-microbiota-interactions-in-triatomine-bugs-and-tsetse-flies-a-vectorial-perspective
#3
REVIEW
Zeph Nelson Omondi, Ayşe Caner, Suha Kenan Arserim
Triatomines (kissing bugs) and tsetse flies (genus: Glossina) are natural vectors of Trypanosoma cruzi and Trypanosoma brucei, respectively. T. cruzi is the causative agent of Chagas disease, endemic in Latin America, while T. brucei causes African sleeping sickness disease in sub-Saharan Africa. Both triatomines and tsetse flies are host to a diverse community of gut microbiota that co-exist with the parasites in the gut. Evidence has shown that the gut microbiota of both vectors plays a key role in parasite development and transmission...
April 23, 2024: Medical and Veterinary Entomology
https://read.qxmd.com/read/38651158/diagnostic-value-of-one-step-nucleic-acid-amplification-for-sentinel-lymph-node-metastasis-in-cytokeratin-19-positive-tumors-evidence-from-bioinformatics-and-meta-analysis
#4
Ke Li, Min Meng, Weiwei Zhang, Junyi Li, Yiting Wang, Changhui Zhou
BACKGROUND: The status of the sentinel lymph nodes (SLNs) was an important prognostic factor in varies cancers. A one-step nucleic acid amplification (OSNA) assay, a molecular-based whole-node analysis method based on CK19 mRNA copy number, was developed to diagnose lymph node metastases. We aimed to evaluate the value of OSNA for the diagnosis of sentinel lymph node metastasis in CK19 positive cancers. CK19 mRNA and protein expression for pan-caner analysis were obtained from TCGA and the Human protein atlas database...
2024: Frontiers in Oncology
https://read.qxmd.com/read/38627605/a-scientometric-analysis-and-visualisation-of-elderly-suicide-research-from-1951-to-2022
#5
JOURNAL ARTICLE
Seher Palanbek Yavaş, Caner Baysan
BACKGROUND: There are still many gaps in both national and international literature on elderly suicide. This study aimed to identify the most influential journals in elderly suicide, the countries and authors that contribute the most to the field, and the trends in the field. MATERIAL AND METHODS: Studies published on elderly suicide between 1951 and 2022 were retrieved utilising the Web of Science Core Collection. Co-authorship analysis of countries and authors, as well as co-occurrence analysis of keywords, were conducted using VOSviewer 1...
April 16, 2024: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://read.qxmd.com/read/38627442/new-treatment-alternatives-for-primary-and-metastatic-colorectal-cancer-by-an-integrated-transcriptome-and-network-analyses
#6
JOURNAL ARTICLE
Caner Karaca, Ezgi Demir Karaman, Asim Leblebici, Hasan Kurter, Hulya Ellidokuz, Altug Koc, Ender Berat Ellidokuz, Zerrin Isik, Yasemin Basbinar
Metastatic colorectal cancer (CRC) is still in need of effective treatments. This study applies a holistic approach to propose new targets for treatment of primary and liver metastatic CRC and investigates their therapeutic potential in-vitro. An integrative analysis of primary and metastatic CRC samples was implemented for alternative target and treatment proposals. Integrated microarray samples were grouped based on a co-expression network analysis. Significant gene modules correlated with primary CRC and metastatic phenotypes were identified...
April 16, 2024: Scientific Reports
https://read.qxmd.com/read/38618499/capacity-for-the-management-of-kidney-failure-in-the-international-society-of-nephrology-eastern-and-central-europe-region-report-from-the-2023-isn-global-kidney-health-atlas-isn-gkha
#7
REVIEW
Caner Alparslan, Jolanta Malyszko, Fergus J Caskey, Mirna Aleckovic-Halilovic, Zdenka Hrušková, Silvia Arruebo, Aminu K Bello, Sandrine Damster, Jo-Ann Donner, Vivekanand Jha, David W Johnson, Adeera Levin, Charu Malik, Masaomi Nangaku, Ikechi G Okpechi, Marcello Tonelli, Feng Ye, Vladimir Tesar, Sanjin Racki
Delivery of care for kidney failure (KF) globally has a significant disparity; even in some countries, it means end of life for the person. The International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA) tries to address gaps in KF care and standardize global nephrology care. From the third iteration of the ISN-GKHA, we present data for countries in the ISN Eastern and Central Europe region. The median prevalences of chronic kidney disease (12.8%) and treated KF (873.5 pmp) were higher than the global rates, respectively...
April 2024: Kidney International Supplements
https://read.qxmd.com/read/38610862/the-effect-of-preoperative-administration-of-glucocorticoids-on-the-postoperative-complication-rate-in-liver-surgery-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#8
REVIEW
Caner Turan, Emőke Henrietta Kovács, László Szabó, Işıl Atakan, Fanni Dembrovszky, Klementina Ocskay, Szilárd Váncsa, Péter Hegyi, László Zubek, Zsolt Molnár
Background : Glucocorticoids may grant a protective effect against postoperative complications. The evidence on their efficacy, however, has been inconclusive thus far. We investigated the effects of preoperatively administered glucocorticoids on the overall postoperative complication rate, and on liver function recovery in patients undergoing major liver surgery. Methods: We performed a systematic literature search on PubMed, Embase, and CENTRAL in October 2021, and repeated the search in April 2023. Pre-study protocol was registered on PROSPERO (ID: CRD42021284559)...
April 3, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38610649/esophagus-dilation-and-quality-of-life-in-adults-with-scleroderma-and-concomitant-obstructive-sleep-apnea
#9
JOURNAL ARTICLE
Tugce Yakut, Caner Cinar, Sait Karakurt, Haner Direskeneli, Yasemin Yalcinkaya, Yüksel Peker
(1) Background : Systemic sclerosis (SSc) is a rare systemic disease, which often affects the esophagus, leading to dilation and complications such as dysphagia and reflux. Obstructive sleep apnea (OSA) is a chronic condition with recurrent episodes of upper airway collapsibility and is known to impair quality of life (QoL). The primary aim of this study was to investigate the occurrence of esophagus dilation in patients with SSc and concomitant OSA and, further, to address the impact of these conditions on QoL...
March 25, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38587562/evaluating-the-predictive-value-of-late-gadolinium-enhancement-assessed-by-cardiac-magnetic-resonance-on-sudden-cardiac-death-in-patients-selected-for-implantable-cardioverter-defibrillator-and-cardiac-resynchronization-therapy-implantation-a-systematic-review
#10
JOURNAL ARTICLE
Richárd Masszi, Előd-János Zsigmond, Réka Ehrenberger, Caner Turan, Péter Fehérvári, Brigitta Teutsch, Zsolt Molnár, Zsófia Drobni, Hajnalka Vágó, Péter Hegyi, Béla Merkely, Annamária Kosztin
AIMS: Late gadolinium enhancement (LGE) assessed by cardiovascular magnetic resonance (CMR) can evaluate myocardial scar associated with a higher risk of sudden cardiac death (SCD), which can guide the selection between cardiac resynchronization therapy with or without a defibrillator (CRT-P/CRT-D). Our aim was to investigate the association between LGE and SCD risk in patients with CRT using the LGE-CMR technique. METHODS AND RESULTS: We performed a systematic literature search using four databases...
April 8, 2024: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://read.qxmd.com/read/38587026/thorax-computed-tomography-ctx-guided-ground-truth-annotation-of-chest-radiographs-cxr-for-improved-classification-and-detection-of-covid-19
#11
JOURNAL ARTICLE
Şükrü Mehmet Ertürk, Tuğçe Toprak, Rana Günöz Cömert, Cemre Candemir, Eda Cingöz, Zeynep Nur Akyol Sari, Celal Caner Ercan, Esin Düvek, Berke Ersoy, Edanur Karapinar, Atadan Tunaci, M Alper Selver
Several data sets have been collected and various artificial intelligence models have been developed for COVID-19 classification and detection from both chest radiography (CXR) and thorax computed tomography (CTX) images. However, the pitfalls and shortcomings of these systems significantly limit their clinical use. In this respect, improving the weaknesses of advanced models can be very effective besides developing new ones. The inability to diagnose ground-glass opacities by conventional CXR has limited the use of this modality in the diagnostic work-up of COVID-19...
April 8, 2024: International Journal for Numerical Methods in Biomedical Engineering
https://read.qxmd.com/read/38580966/comprehensive-analyses-of-the-cancer-associated-fibroblast-subtypes-and-their-score-system-for-prediction-of-outcomes-and-immunosuppressive-microenvironment-in-prostate-cancer
#12
JOURNAL ARTICLE
Ze Gao, Ning Zhang, Bingzheng An, Dawei Li, Zhiqing Fang, Dawei Xu
BACKGROUND: Cancer-associated fibroblasts (CAFs) drive cancer progression and treatment failure on one hand, while their tumor-restraining functions are also observed on the other. Recent single cell RNA sequencing (scRNA-seq) analyses demonstrates heterogeneity of CAFs and defines molecular subtypes of CAFs, which help explain their different functions. However, it remains unclear whether these CAF subtypes have the same or different biological/clinical implications in prostate cancer (PCa) or other malignancies...
April 5, 2024: Cancer Cell International
https://read.qxmd.com/read/38578389/covid-19-vaccination-in-patients-with-inborn-errors-of-immunity-reduces-hospitalization-and-critical-care-needs-related-to-covid-19-a-usidnet-report
#13
JOURNAL ARTICLE
John McDonnell, Kimberley Cousins, M Elizabeth M Younger, Adam Lane, Hassan Abolhassani, Roshini S Abraham, Salem Al-Tamemi, Juan Carlos Aldave-Becerra, Eman Hesham Al-Faris, Alberto Alfaro-Murillo, Suzan A AlKhater, Nouf Alsaati, Alexa Michelle Altman Doss, Melissa Anderson, Ernestina Angarola, Barbara Ariue, Danielle E Arnold, Amal H Assa'ad, Caner Aytekin, Meaghan Bank, Jenna R E Bergerson, Jack Bleesing, John Boesing, Carolina Bouso, Nicholas Brodszki, Diana Cabanillas, Carol Cady, Meghan A Callahan, Roberta Caorsi, Javier Carbone, Maria Carrabba, Riccardo Castagnoli, Jason R Catanzaro, Samantha Chan, Sharat Chandra, Hugo Chapdelaine, Zahra Chavoshzadeh, Hey Jin Chong, Lori Connors, Filippo Consonni, Oscar Correa-Jimenez, Charlotte Cunningham-Rundles, Katherine D'Astous-Gauthier, Ottavia Maria Delmonte, Yesim Yilmaz Demirdag, Deepti R Deshpande, Natalie M Diaz-Cabrera, Victoria R Dimitriades, Rasha El-Owaidy, Gehad ElGhazali, Suleiman Al-Hammadi, Giovanna Fabio, Astrid Schellnast Faure, Jin Feng, James M Fernandez, Lauren Fill, Guacira R Franco, Robert W Frenck, Ramsay L Fuleihan, Giuliana Giardino, Jessica Galant-Swafford, Eleonora Gambineri, Elizabeth K Garabedian, Ashley V Geerlinks, Ekaterini Goudouris, Octavio Grecco, Qiang Pan-Hammarström, Hedieh Haji Khodaverdi Khani, Lennart Hammarström, Nicholas L Hartog, Jennifer Heimall, Gabriela Hernandez-Molina, Caroline C Horner, Robert W Hostoffer, Nataliya Hristova, Kuang-Chih Hsiao, Gabriela Ivankovich-Escoto, Faris Jaber, Maaz Jalil, Mahnaz Jamee, Tiffany Jean, Stephanie Jeong, Devi Jhaveri, Michael B Jordan, Avni Y Joshi, Amanpreet Kalkat, Henry J Kanarek, Erinn S Kellner, Amer Khojah, Ruby Khoury, Cristina M Kokron, Ashish Kumar, Kelsey Lecerf, Heather K Lehman, Jennifer W Leiding, Harry Lesmana, Xin Rong Lim, Joao Pedro Lopes, Ana Laura López, Lucia Tarquini, Ingrid S Lundgren, Julieann Magnusson, Ana Karolina B B Marinho, Gian Luigi Marseglia, Giulia M Martone, Annamaria G Mechtler, Leonardo Mendonca, Joshua D Milner, Peter J Mustillo, Asal Gharib Naderi, Samuele Naviglio, Jeremy Nell, Hana B Niebur, Luigi Notarangelo, Matias Oleastro, María Claudia Ortega-López, Neil R Patel, Gordana Petrovic, Claudio Pignata, Oscar Porras, Benjamin T Prince, Jennifer M Puck, Nashmia Qamar, Marco Rabusin, Nikita Raje, Lorena Regairaz, Kimberly A Risma, Elizabeth H Ristagno, John Routes, Persio Roxo-Junior, Negin Salemi, Christopher Scalchunes, Susan J Schuval, Suranjith L Seneviratne, Ashwin Shankar, Roya Sherkat, Junghee Jenny Shin, Abeer Siddiqi, Sara Signa, Ali Sobh, Fabiana Mascarenhas Souza Lima, Kristen K Stenehjem, Jonathan S Tam, Monica Tang, Myrthes Toledo Barros, James Verbsky, Eleni Vergadi, Dayne H Voelker, Stefano Volpi, Luke A Wall, Christine Wang, Kelli W Williams, Eveline Y Wu, Shan Shan Wu, Jessie J Zhou, Alexandria Cook, Kathleen E Sullivan, Rebecca Marsh
BACKGROUND: The CDC and ACIP recommend COVID-19 vaccination for patients with inborn errors of immunity (IEI). Not much is known about vaccine safety in IEI, and whether vaccination attenuates infection severity in IEI. OBJECTIVE: To estimate COVID-19 vaccination safety and examine effect on outcomes in patients with IEI. METHODS: We built a secure registry database in conjunction with the US Immunodeficiency Network to examine vaccination frequency and indicators of safety and effectiveness in IEI patients...
April 5, 2024: Journal of Clinical Immunology
https://read.qxmd.com/read/38577850/medical-care-as-flea-market-bargaining-an-international-interdisciplinary-study-of-varieties-of-shared-decision-making-in-physician-patient-interactions
#14
JOURNAL ARTICLE
Ilka Sommer, Solmaz Assa, Cadja Bachmann, Wei Chen 陈未, Melih Elcin, Elisabeth Funk, Caner Kamisli, Tao Liu 刘涛, Alexander H Maass, Stefanie Merse, Caroline Morbach, Anja Neumann, Till Neumann, Benjamin Quasinowski, Stefan Störk, Sarah Weingartz, Götz Wietasch, Anja Weiss Weiß
Phenomenon : Shared decision making (SDM) is a core ideal in the interaction between healthcare providers and patients, but the implementation of the SDM ideal in clinical routines has been a relatively slow process. Approach : In a sociological study, 71 interactions between physicians and simulated patients enacting chronic heart failure were video-recorded in China, Germany, the Netherlands, and Turkey as part of a quasi-experimental research design. Participating physicians varied in specialty and level of experience...
April 5, 2024: Teaching and Learning in Medicine
https://read.qxmd.com/read/38572819/change-in-the-neutrophil-lymphocyte-ratio-may-predict-early-recurrence-in-operated-bladder-cancer
#15
JOURNAL ARTICLE
Rumeysa Çolak, Gökmen Umut Erdem, Caner Kapar, İlkay Gültürk, Faruk Aksu, Gülçin Şahingöz Erdal, Mesut Yılmaz, Deniz Tural
BACKGROUND: Recurrence develops in 50% of operated bladder cancer patients. It is important to detect recurrence in advance, and there is no prognostic reliable biomarker for bladder cancer. OBJECTIVE: The aim of this study is to show that changes in hematological parameters before radiological imaging can predict recurrence. METHODS: We performed a retrospective cohort study of patients undergoing radical cystectomy for urothelial carcinoma of the bladder identified using our institutional database (2010-2022)...
April 4, 2024: Asia-Pacific Journal of Clinical Oncology
https://read.qxmd.com/read/38561203/can-dynamic-spinal-stabilization-be-an-alternative-to-fusion-surgery-in-adult-spinal-deformity-cases
#16
JOURNAL ARTICLE
Ali Fahir Ozer, Mehmet Yigit Akgun, Ege Anil Ucar, Mehdi Hekimoglu, Ahmet Tulgar Basak, Caner Gunerbuyuk, Sureyya Toklu, Tunc Oktenoglu, Mehdi Sasani, Turgut Akgul, Ozkan Ates
BACKGROUND: Rigid stabilization and fusion surgery are widely used for the correction of spinal sagittal and coronal imbalance (SCI). However, instrument failure, pseudoarthrosis, and adjacent segment disease are frequent complications of rigid stabilization and fusion surgery in elderly patients. In this study, we present the results of dynamic stabilization and 2-stage dynamic stabilization surgery for the treatment of spinal SCI. The advantages and disadvantages are discussed, especially as an alternative to fusion surgery...
April 1, 2024: International Journal of Spine Surgery
https://read.qxmd.com/read/38554370/immunotherapy-experience-in-sinonasal-nut-midline-carcinoma-case-report
#17
JOURNAL ARTICLE
Burcu Caner, Sibel O Orhan, Adem Deligonul, Turkkan Evrensel
NUT midline carcinoma (NMC) is an aggressive malignant neoplasm arising from midline structures. Although it is classified as a rare disease, the pathological nonspecific appearance as undifferentiated/poorly differentiated carcinoma and the difficulty in making the definitive diagnosis are probably the reasons for the underdiagnosis; the disease is thought to be more prevalent. There is no standard treatment for the disease. The disease shows a poor response to chemotherapy and radiotherapy, and patients' survival is poor...
January 1, 2024: Journal of Cancer Research and Therapeutics
https://read.qxmd.com/read/38547029/pain-neuroscience-education-following-arthroscopic-rotator-cuff-repair-for-patients-with-rotator-cuff-tears-a-double-blind-randomized-controlled-clinical-trial
#18
JOURNAL ARTICLE
Caner Kararti, Fatih Özyurt, Muhammed İhsan Kodak, Hakkı Çağdaş, Gülşah Özsoy, İsmail Özsoy, Abdulhamit Tayfur
OBJECTIVE: This trial examines the efficacy of the Pain Neuroscience Education (PNE) on clinical outcomes in patients with arthroscopic rotator cuff repair (ARCR). DESIGN: A total of 36 participants undergoing ARCR were assigned to either the experimental group (n = 18) or control group (n = 18) in this randomized study. A 6-week-long conventional physiotherapy program was administered for both groups. In addition, a PNE protocol was administered for the experimental group for a whole period of 6 weeks (one session/week, 15-60 min per session)...
March 25, 2024: American Journal of Physical Medicine & Rehabilitation
https://read.qxmd.com/read/38530698/ultrasound-guided-radial-artery-puncture-by-nurses-in-emergency-department-a-randomized-controlled-study
#19
JOURNAL ARTICLE
Birdal Güllüpınar, Caner Sağlam, Arif Karagöz, Serhat Koran, Erden Erol Ünlüer
INTRODUCTION: Radial artery puncture has been performed by palpation as a standard method in many emergency departments and intensive care units. Nurses play an important role in the care of patients in various settings. Ultrasonography can be performed and interpreted not only by physicians but also by nurses. This study aimed to evaluate whether emergency nurses would be more successful in radial artery puncture procedure by using ultrasonography instead of palpation. METHODS: This single-center, prospective, randomized controlled study was conducted in the emergency department...
March 26, 2024: Journal of Emergency Nursing: JEN: Official Publication of the Emergency Department Nurses Association
https://read.qxmd.com/read/38527384/integrating-spatial-temporal-soundscape-mapping-with-landscape-indicators-for-effective-conservation-management-and-planning-of-a-protected-area
#20
JOURNAL ARTICLE
Xiaoqing Xu, Caner Baydur, Jingjie Feng, Chengzhao Wu
Protected areas (PAs) possess generous biodiversity, making them great potential for human and wildlife well-being. Nevertheless, rising anthropogenic sounds may pose a serious challenge and threat to the habitats. Therefore, understanding the acoustic environments of PAs and implementing proper conservation strategies are essential for maintaining species richness within the territory. In this study, we investigate the spatial-temporal variations of soundscape distribution in the Dashanbao Protected Area (DPA) of China, ultimately discussing the planning and management strategies...
March 24, 2024: Journal of Environmental Management
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