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https://www.readbyqxmd.com/read/29755825/bilateral-asymmetric-rhegmatogenous-retinal-detachment-in-a-patient-with-stickler-syndrome
#1
Caner Öztürk, Almila Sarıgül Sezenöz, Gürsel Yılmaz, İmren Akkoyun
Here we present the long-term anatomical and visual outcomes of bilateral asymmetric rhegmatogenous retinal detachment repair in a patient with Stickler syndrome. A 17-year-old girl presented with decreased visual acuity in both eyes for more than one year. Her best-corrected visual acuity (BCVA) was 0.1 in the right eye and 0.05 in the left eye. Slit-lamp anterior segment examination revealed subcapsular cataract in both eyes. Fundus examination showed bilateral rhegmatogenous retinal detachment, chronic retinal detachment accompanied by multiple retinal holes, tears and membranous fibrillary vitreous in the peripheral retina...
April 2018: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/29748714/morphological-and-molecular-analyses-of-bipteria-lusitanica-n-sp-in-wild-white-seabream-diplodus-sargus-linnaeus-1758-in-portugal
#2
Caner Sirin, Maria J Santos, Luis F Rangel
The present study records the presence of Bipteria lusitanica n. sp. in wild white seabream, Diplodus sargus (Linnaeus, 1758) off the Portuguese coast. Myxosporean parasites were found in the interstitial tissue of kidney and free in urinary bladder of D. sargus with a 33.3% of prevalence of infection. Myxospores were triangular or inversely pyramidal in shape and anteriorly wider in frontal view, measuring 11.2 ± 1.0 μm in length, 12.6 ± 0.9 μm in width, and 11.6 ± 0.4 μm in thickness. The sinuous sutural line was parallel to the axis that connects the center of the two polar capsules...
May 11, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29724973/rationale-design-and-methodology-of-the-apollon-trial-a-comprehensive-observational-registry-of-heart-failure-with-midrange-and-preserved-ejection-fraction
#3
Bülent Özlek, Eda Özlek, Oğuzhan Çelik, Cem Çil, Volkan Doğan, Mehmet Tekinalp, Hicaz Zencirkıran Ağuş, Serkan Kahraman, Altuğ Ösken, İbrahim Rencüzoğulları, Veysel Ozan Tanık, Lütfü Bekar, Mustafa Ozan Çakır, Bedri Caner Kaya, Hakan Tibilli, Yunus Çelik, Özcan Başaran, Kadir Uğur Mert, Samet Sevinç, Erkan Demirci, Engin Dondurmacı, Murat Biteker
OBJECTIVE: Although almost half of chronic heart failure (HF) patients have mid-range (HFmrEF) and preserved left-ventricular ejection fraction (HFpEF), no studies have been carried out with these patients in our country. This study aims to determine the demographic characteristics and current status of the clinical background of HFmrEF and HFpEF patients in a multicenter trial. METHODS: A comPrehensive, ObservationaL registry of heart faiLure with mid range and preserved ejectiON fraction (APOLLON) trial will be an observational, multicenter, and noninterventional study conducted in Turkey...
May 2018: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/29685926/is-there-a-need-for-additional-dq-matching
#4
EDITORIAL
Caner Süsal, Martin Zeier
No abstract text is available yet for this article.
May 7, 2018: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/29678199/megan-lr-new-algorithms-allow-accurate-binning-and-easy-interactive-exploration-of-metagenomic-long-reads-and-contigs
#5
Daniel H Huson, Benjamin Albrecht, Caner Bağcı, Irina Bessarab, Anna Górska, Dino Jolic, Rohan B H Williams
BACKGROUND: There are numerous computational tools for taxonomic or functional analysis of microbiome samples, optimized to run on hundreds of millions of short, high quality sequencing reads. Programs such as MEGAN allow the user to interactively navigate these large datasets. Long read sequencing technologies continue to improve and produce increasing numbers of longer reads (of varying lengths in the range of 10k-1M bps, say), but of low quality. There is an increasing interest in using long reads in microbiome sequencing, and there is a need to adapt short read tools to long read datasets...
April 20, 2018: Biology Direct
https://www.readbyqxmd.com/read/29668348/phosphatidylserine-and-gtpase-activation-control-cdc42-nanoclustering-to-counter-dissipative-diffusion
#6
Elodie Sartorel, Caner Ünlü, Mini Jose, Aurélie Massoni-Laporte, Julien Meca, Jean-Baptiste Sibarita, Derek McCusker
The anisotropic organization of plasma membrane constituents is indicative of mechanisms that drive the membrane away from equilibrium. However, defining these mechanisms is challenging due to the short spatio-temporal scales at which diffusion operates. Here, we use high-density single protein tracking combined with photoactivation localization microscopy (sptPALM) to monitor Cdc42 in budding yeast, a system in which Cdc42 exhibits anisotropic organization. Cdc42 exhibited reduced mobility at the cell pole, where it was organized in nanoclusters...
April 18, 2018: Molecular Biology of the Cell
https://www.readbyqxmd.com/read/29625089/a-possible-molecular-basis-for-photoprotection-in-the-minor-antenna-proteins-of-plants
#7
Kieran F Fox, Caner Ünlü, Vytautas Balevičius, Baboo Narottamsing Ramdour, Carina Kern, Xiaowei Pan, Mei Li, Herbert van Amerongen, Christopher D P Duffy
The bioenergetics of light-harvesting by photosynthetic antenna proteins in higher plants is well understood. However, investigation into the regulatory non-photochemical quenching (NPQ) mechanism, which dissipates excess energy in high light, has led to several conflicting models. It is generally accepted that the major photosystem II antenna protein, LHCII, is the site of NPQ, although the minor antenna complexes (CP24/26/29) are also proposed as alternative/additional NPQ sites. LHCII crystals were shown to exhibit the short excitation lifetime and several spectral signatures of the quenched state...
April 3, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29616661/shell-feature-a-new-radiomics-descriptor-for-predicting-distant-failure-after-radiotherapy-in-non-small-cell-lung-cancer-and-cervix-cancer
#8
Hongxia Hao, Zhiguo Zhou, Shulong Li, Genevieve Maquilan, Michael R Folkert, Puneeth Iyengar, Kenneth D Westover, Kevin Albuquerque, Fang Liu, Hak Choy, Robert Timmerman, Lin Yang, Jing Wang
Distant failure is the main cause of human cancer-related mortalities. To develop a model for predicting distant failure in non-small cell lung cancer (NSCLC) and cervix cancer (CC) patients, a shell feature, consisting of outer voxels around the tumor boundary, was constructed using pre-treatment positron emission tomography (PET) images from 48 NSCLC patients received stereotactic body radiation therapy and 52 CC patients underwent external beam radiation therapy and concurrent chemotherapy followed with high-dose-rate intracavitary brachytherapy...
May 2, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29608481/bilateral-post-traumatic-facial-paralysis-that-contains-longitudinal-and-transverse-temporal-fracture
#9
Caner Şahin, Özkan Özen
Acute bilateral post-traumatic facial paralysis is rare in the literature. Post-traumatic facial paralysis is frequently accompanied transverse fractures of temporal more. The incidence of acute bilateral post-traumatic facial paralysis has been reported as 1 to 5 per million in the literature. Trauma and concurrent facial paralysis are usually in the same subsite (right temporal bone fracture and right facial paralysis). There is one pathophysiological pattern for a single temporal bone fracture in a subsite...
March 30, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29599319/aberrant-expression-of-piwil1-and-piwil2-and-their-clinical-significance-in-ductal-breast-carcinoma
#10
Monika Litwin, Anna Szczepańska-Buda, Dagmara Michałowska, Jędrzej Grzegrzółka, Aleksandra Piotrowska, Agnieszka Gomułkiewicz, Andrzej Wojnar, Piotr Dzięgiel, Wojciech Witkiewicz
BACKGROUND/AIM: P-Element-induced wimpy testis (PIWI) proteins in complex with PIWI-interacting RNA (piRNA) are involved in epigenetic regulation of gene expression in germline cells. Aberrant expression of piRNA and PIWI proteins have been identified in various types of tumour cells. The aim of this study was to evaluate the expression profiles of PIWI-like protein-1, -2 (PIWIL1 and PIWIL2), their immunohistochemical (IHC) characteristics in ductal breast cancer, and determine their correlation with clinicopathological parameters of this type of cancer...
April 2018: Anticancer Research
https://www.readbyqxmd.com/read/29593803/can-we-define-migraine-patients-with-blood-high-sensitivity-c-reactive-protein-and-galectin-3-levels-in-the-emergency-department
#11
Mehtap Gürger, Metin Atescelik, Mustafa Yilmaz, Mustafa Yildiz, Hatice Kalayci, Mehmet Ali Kobat, Caner Fevzi Demir
Introduction: Migraine, the most widespread cause of headache in young adults, is a frequent reason for presentation to emergency departments. The aim of this study was to determine the diagnostic value of serum galectin-3 and high-sensitivity C-reactive protein (hsCRP) levels in migraine patients. Material and methods: Serum galectin-3 and hsCRP levels were measured using enzyme-linked immunosorbent assay in 70 migraine patients and 70 healthy control subjects...
March 2018: Archives of Medical Science: AMS
https://www.readbyqxmd.com/read/29578925/successful-management-of-a-rare-cause-of-hemolytic-uremic-syndrome-with-eculizumab-in-a-child
#12
Caner Alparslan, Önder Yavaşcan, Belde Kasap Demir, Bahriye Atmiş, Aysun Karabay Bayazit, Göksel Leblebisatan, Elif P Öncel, Demet Alaygut, Fatma Mutlubaş, Nejat Aksu
BACKGROUND: Hemolytic uremic syndrome (HUS) is characterized by microangiopathic hemolytic anemia, acute renal failure, and thrombocytopenia. It very rarely coexists with acute lymphoblastic leukemia (ALL) emerging before, simultaneously, or after the diagnosis has been made, and management of the patient may be difficult. CASE: We present the case of a 7-year-old boy who was diagnosed with HUS and initially managed by hemodialysis (HD). Thereafter, HUS progressed, and neurological findings developed...
March 23, 2018: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/29564414/intravitreal-bevacizumab-as-rescue-therapy-following-treatment-failure-with-laser-photocoagulation-in-retinopathy-of-prematurity
#13
Caner Kara, Emre Hekimoğlu, İkbal Seza Petriçli, Handan Akıl
Purpose: To evaluate the efficacy of intravitreal bevacizumab (IVB) in case of treatment failure with laser photocoagulation in retinopathy of prematurity (ROP). Methods: A retrospective review of infants treated with IVB injection due to treatment failure with laser photocoagulation was performed. The anatomical results and complications were evaluated after treatment. Results: 9 eyes of 6 premature infants with a mean gestational age of 26...
March 2018: Journal of Current Ophthalmology
https://www.readbyqxmd.com/read/29554067/osteosarcoma-of-the-ethmoid-sinus
#14
Zülküf Burak Erdur, Emine Deniz Gözen, Hakki Caner Inan, Haydar Murat Yener, Nil Çomunoğlu, Cansu Yol, Çiğdem Papila, Harun Cansiz
Osteosarcoma (OS) is a malignant bone tumor and it is very rare in head and neck region. If it arises in this area, most common localizations of this tumor are mandible and maxilla and ethmoid sinus is very rare site for this malignancy. A 43-year-old female admitted to our clinic with the complaint of pain in the right half of the face and headache persisting for 2 months. According to the clinical symptoms and imaging studies, sinonasal ossifying fibroma was suspected. For this reason, patient was operated endoscopically and histopathological examination revealed that osteoid matrix producing atypical osteoblastic cells so these findings identified osteoblastic variant OS...
March 16, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29511555/impact-of-age-at-diagnosis-on-disease-progression-in-patients-with-primary-sclerosing-cholangitis
#15
Christian Rupp, Alexander Rössler, Taotao Zhou, Conrad Rauber, Kilian Friedrich, Andreas Wannhoff, Karl-Heinz Weiss, Peter Sauer, Peter Schirmacher, Caner Süsal, Wolfgang Stremmel, Daniel N Gotthardt
Background: The median age of diagnosis of primary sclerosing cholangitis (PSC) is ∼30-40 years. Objective: We aimed to analyse disease progression and liver-dependent survival in patients diagnosed with PSC after 50 years of age. Methods: Patients with PSC were analysed with regard to their age at diagnosis. Patients with a first diagnosis of PSC after the age of 50 years were considered as the late-onset group. Results: A total of 32/215 (14...
March 2018: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29502365/-molecular-origins-of-cancer-and-future-cancer-therapy
#16
L Xie, W J Hu, B R Liu
The accumulation of genomic and epigenetic changes gives rise to the tumorigenesis and progression. Currently, clonal evolution model and cancer stem cell model, two leading theories of caner origin, are becoming complementary to one another to explain the nature of tumor heterogeneity. Precision medicine that is based on the next generation sequencing and big data describes the phenomena of tumor heterogeneity more precisely. The future cancer therapy may need more comprehensive and dynamical understandings of the distinct subclones of tumor and follow the trends of cancer evolution...
February 23, 2018: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29496058/real-time-indocyanin-green-near-infrared-lymphangiography-for-the-reduction-of-drainage-volume-after-neck-dissection
#17
Jimmy Yu Wai Chan, Stanley Thian Sze Wong, William Ignace Wei
BACKGROUND: To investigate the role of indocyanine green (ICG) lymphangiography in the reduction of drainage after neck dissection. METHODS: Patients with oral cavity squamous cell carcinoma were randomized into Group A (study group) and Group B (control). In the study group, upon the completion of neck dissection, a total of 2.5 mg of ICG was injected submucosally at the four quadrants around the tumour. Another 2.5 mg of ICG was injected subdermally in the groin bilaterally...
March 2018: Oral Oncology
https://www.readbyqxmd.com/read/29487437/determination-of-the-microbial-flora-in-traditional-%C3%A4-zmir-tulum-cheeses-by-denaturing-gradient-gel-electrophoresis
#18
Burcin Karabey, Didem Eroglu, Caner Vural, Guven Ozdemir, Oktay Yerlikaya, Ozer Kinik
In this study, it was aimed to determine microbial flora members in three traditional Tulum cheeses (C1, C2 and C3) produced in different villages and settlement areas in İzmir, Turkey. For this purpose, culture depended and 16S rRNA based culture independent methods were used. According to the results of culture depended method, Lactococcus spp., Enterococcus spp., Staphylococcus spp., Lactobacillus spp., Pediococcus spp. and yeast-mold were detected in all samples at different levels. In order to determine and identify both of the culturable and non-culturable microorganisms, denaturing gradient gel electrophoresis (DGGE) method was used...
March 2018: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29485097/increased-expression-of-interleukin-18-mrna-is-associated-with-carotid-artery-stenosis
#19
Berk Arapi, Burcu Bayoğlu, Müjgan Cengiz, Ahmet Dirican, Serkan Burç Deser, Yerik Junusbekov, Caner Arslan
BACKGROUND: Carotid artery stenosis (CAS) is the atherosclerotic narrowing of the proximal internal carotid artery (ICA) and one of the main causes of stroke. Elevated expression of the pleiotropic proinflammatory cytokine, interleukin-18 (IL18), has been shown in human atherosclerotic plaques. AIMS: To investigate whether IL18 and interleukin-18 binding protein (IL18BP) mRNA expression and IL18 -137 G/C (rs187238) variants are associated with CAS development. STUDY DESIGN: Case-control study...
February 27, 2018: Balkan Medical Journal
https://www.readbyqxmd.com/read/29484508/undifferentiated-headache-broadening-the-approach-to-headache-in-children-and-adolescents-with-supporting-evidence-from-a-nationwide-school-based-cross-sectional-survey-in-turkey
#20
Christian Wöber, Çiçek Wöber-Bingöl, Derya Uluduz, Tuna Stefan Aslan, Uğur Uygunoglu, Ahmet Tüfekçi, Selen Ilhan Alp, Taşkın Duman, Fidan Sürgün, Gülser Karadaban Emir, Caner Feyzi Demir, Ferhat Balgetir, Yeliz Bahar Özdemir, Tanja Auer, Aksel Siva, Timothy J Steiner
BACKGROUND: Headache is a leading disabler in adults worldwide. In children and adolescents, the same may be true but the evidence is much poorer. It is notable that published epidemiological studies of these age groups have largely ignored headaches not fulfilling any specific set of ICHD criteria, although such headaches appear to be common. A new approach to these is needed: here we introduce, and investigate, a diagnostic category termed "undifferentiated headache" (UdH), defined in young people as recurrent mild-intensity headache of < 1 h's duration...
February 27, 2018: Journal of Headache and Pain
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