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https://www.readbyqxmd.com/read/28493774/urinary-catheter-related-visits-to-the-emergency-department-and-implications-for-community-services
#1
Tiziana Ansell, Danielle Harari
Thousands of patients live with urinary catheters and the potential complications deriving from long-term use. Disjointed community services may result in patients attending the emergency department (ED) to manage catheter complications. AIM: to conduct a service review of catheterised patients attending the ED of a large London hospital; to describe incidence, reasons for attendance and cost to inform future planning for out-of-hospital care. METHOD: a catheter collaborative, consisting of multidisciplinary health professionals and patients, formulated survey questions...
May 11, 2017: British Journal of Nursing: BJN
https://www.readbyqxmd.com/read/28493506/alemtuzumab-dose-adjusted-for-body-weight-is-associated-with-earlier-lymphocyte-repletion-and-less-infective-episodes-in-the-first-year-post-renal-transplantation
#2
Michelle Willicombe, Dawn Goodall, Adam G McLean, David Taube
The optimal dose of alemtuzumab for renal transplant induction is not known and the doses reported in the literature vary. This study compares 2 separate dosing regimens of alemtuzumab in renal transplantation. The first is a standard fixed dose of 30mg (SD) and the second is a dose adjusted for body weight at 0.04mg/kg (AD). In this first-year post transplant, there was no difference in patient [HR 0.64 (0.22-1.86), p=0.39] or allograft survival [HR 1.18 (0.48-2.90), p=0.72] between the two groups. There was also no difference in overall rejection free survival [HR 1...
May 11, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28470334/transrectal-ultrasound-guided-prostate-biopsy-in-the-era-of-increasing-fluoroquinolone-resistance-prophylaxis-with-single-dose-ertapenem
#3
Michael Seitz, Christian Stief, Raphaela Waidelich, Markus Bader, Derya Tilki
PURPOSE: The aim of the study was to compare single-dose ertapenem (ERT) with the 3-day regime of ciprofloxacin (CIP) for prophylaxis of possible infections following transrectal prostate biopsy. METHODS: Data from a consecutive group of 542 patients from January 2012 to January 2017 were retrospectively analysed. As preinterventional prophylaxis patient group A (179) received 500 mg CIP twice a day for three days, beginning on the day before the biopsy (until June 2013); group B (363) received a single dose of ERT 60 min prior to intervention...
May 3, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28461995/is-a-ureteral-stent-required-after-use-of-ureteral-access-sheath-in-presented-patients-who-undergo-flexible-ureteroscopy
#4
Gastón Astroza, Manuel Catalán, Lucas Consigliere, Tomás Selman, José Salvadó, Francisco Rubilar
INTRODUCTION: Use of a ureteral access sheath (UAS) within flexible ureteroscopy (fURS) for the management of kidney and ureteral stones has shown improvements in its effectiveness, but it is also associated with increased risk of ureteral injury. Use of ureteral stent (US) after fURS is recommended by some authors, because of its role in reducing postoperative pain and preventing complications. Our objective is to determine if postoperative stenting is necessary in pre-stented patients that underwent fURS using UAS...
2017: Central European Journal of Urology
https://www.readbyqxmd.com/read/28450555/integrating-mri-and-chemokine-receptor-cxcr4-targeted-pet-for-detection-of-leukocyte-infiltration-in-complicated-urinary-tract-infections-after-kidney-transplantation
#5
Thorsten Derlin, Faikah Gueler, Jan H Bräsen, Jessica Schmitz, Dagmar Hartung, Thomas R Herrmann, Tobias L Ross, Frank Wacker, Hans-Jürgen Wester, Marcus Hiss, Hermann Haller, Frank M Bengel, Katja Hueper
Complicated urinary tract infections (UTIs) are frequent in immunosuppressed patients after kidney transplantation and may lead to allograft failure or urosepsis. Non-invasive detection of allograft involvement as well as localization of the primary site of infection are challenging. Therefore, we sought to determine whether molecular-targeted positron emission tomography (PET), combined with diffusion-weighted magnetic resonance imaging (MRI), enables detection of leukocytes in renal allografts. Methods: Thirteen kidney transplant recipients with complicated UTIs underwent both PET with a specific CXCR4-ligand, (68)Ga-Pentixafor, and diffusion-weighted MRI...
April 27, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28439032/inactivation-of-transcriptional-regulators-during-within-household-evolution-of-escherichia-coli
#6
Dagmara I Kisiela, Matthew Radey, Sandip Paul, Stephen Porter, Kseniya Polukhina, Veronika Tchesnokova, Sofiya Shevchenko, Diana Chan, Maliha Aziz, Timothy J Johnson, Lance B Price, James R Johnson, Evgeni V Sokurenko
We analyzed the within-household evolution of two household-associated Escherichia coli strains from pandemic clonal group ST131-H30, using isolates recovered from five individuals within two families, each of which had a distinct strain. Family 1's strain was represented by a urine isolate from the index patient (older sister) with recurrent cystitis, and a blood isolate from her younger sister with fatal urosepsis. Family 2's strain was represented by a urine isolate from the index patient (father) with pyelonephritis and renal abscesses, blood and kidney drainage isolates from the daughter with emphysematous pyelonephritis, and urine and fecal isolates from the mother with cystitis...
April 24, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28437674/laparoscopic-approach-to-colo-renal-fistula-with-renal-preservation-and-omentoplasty-a-case-report
#7
Awais Ashfaq, Robert Ferrigni, Nitin Mishra
Colorenal fistula as a result of percutaneous cryoablation has not been extensively reported. We report a gentleman who presented with urosepsis after percutaneous biopsy of a renal mass complicated by colorenal fistula. After failed attempts at conservative management, he underwent laparoscopic resection of his fistula with renal salvage and omentoplasty highlighting that nephrectomy is not always indicated.
April 4, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28435791/emphysematous-pyelonephritis-with-renal-artery-pseudoaneurysm
#8
Kevin Koo, Elias S Hyams
Emphysematous pyelonephritis is an acute infection of the renal parenchyma and perinephric tissues caused by gas-forming microorganisms, resulting in the radiographic presence of gas in the kidney, collecting system, and surrounding spaces. Here we present a case of severe emphysematous pyelonephritis in the setting of Klebsiella urosepsis. Surgical exploration of the flank revealed infectious disintegration of the renal parenchyma into a large phlegmon. The post-operative course was complicated by renal artery pseudoaneurysm and cutaneous fistualization of a perinephric fluid collection...
July 2017: Urology Case Reports
https://www.readbyqxmd.com/read/28391485/pelvic-organ-prolapse-surgery-in-elderly-patients
#9
Juliane Farthmann, Dirk Watermann, Haiko Zamperoni, Christopher Wolf, Thomas Fink, Boris Gabriel
PURPOSE: Pelvic organ prolapse (POP) can cause incomplete bladder emptying or hydronephrosis and renal failure. These are serious conditions, especially in elderly women, requiring resolution of POP. Pessary use is an alternative, but there are specific problems or patients may not want it. We therefore conducted a retrospective study on surgical treatment of elderly women with respect to the type of surgery and intra- and postoperative complications. METHODS: From two urogynecologic centers, we reviewed treatment data between 2003 and 2013, including patients ≥80 years of age...
April 8, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28377080/-flexible-ureterorenoscopy-and-laser-lithotripsy-for-upper-urinary-tract-stones-in-neurologic-patients-with-severe-motor-disability
#10
F-X Madec, E Suply, F Luyckx, M Nedelec, Y Chowaniec, J Branchereau, L Le Normand, P Glemain
OBJECTIVE: The study's objective was to evaluate the effectiveness and morbidity of flexible ureterorenoscopy and laser lithotripsy for upper urinary tract stones in patients with a nervous system pathology including severe motor disability. METHODS: Between 2006 and 2013, we retrospectively analyzed 83 flexible ureterorenoscopy to treat 63 kidneys in 42 patients. Stone free (SF) kidneys defined as an absence of stones on computerized tomography, renal ultrasound, X-ray or direct ureterorenoscopy, were considered a surgical success...
May 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28360956/shock-due-to-urosepsis-a-multicentre-study
#11
Fukashi Yamamichi, Katsumi Shigemura, Koichi Kitagawa, Kei Takaba, Issei Tokimatsu, Soichi Arakawa, Masato Fujisawa
INTRODUCTION: Urosepsis is a severe infection that can cause shock afterwards. The purpose of this study is to investigate the clinical and bacterial risk factors for shock in those cases with urosepsis caused by urinary tract infection in a multicentre study. METHODS: Our study included 77 consecutive urosepsis cases from four hospitals. We examined factors such as patient characteristics, underlying disease, serum white blood cell (WBC) count, platelet count, C-reactive protein (CRP) level at the time of diagnosis of urosepsis, urinary tract occlusion, causative bacteria, and bacterial antibiotic susceptibilities...
March 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28340257/cd8-positive-t-cell-leukoencephalitis-with-astrocytopathy-clinically-presenting-as-neuromyelitis-optica
#12
Diana L Thomas, Jody Manners, Daniel Marker, Joseph Mettenburg, Geoffrey Murdoch, Bryan Stevens, Guoji Wang, Clayton Wiley
We describe a novel disease entity with the clinical and radiologic presentation of neuromyelitis optica (NMO) and widespread CD8-positive T-cell leukoencephalitis and astrocytopathy. The 59-year-old female patient had a complex 2-year neurological history that included early changes in cognition and memory, progressive lower extremity motor dysfunction, and multimodal sensory involvement. MRI of the spinal cord showed increased T2 signal in the central cord extending from C2 through T4. MRI of the brain showed symmetric radial enhancement in periventricular deep white matter without evidence of demyelinating lesions...
May 1, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28320713/antimicrobial-percutaneous-nephrostomy-catheters-for-the-prevention-of-renal-infections-in-vitro-studies
#13
Nylev Vargas-Cruz, Ruth A Reitzel, Joel Rosenblatt, Mohamed Jamal, Ariel D Szvalb, Anne-Marie Chaftari, Ray Hachem, Issam Raad
Purpose - Percutaneous nephrostomy (PCN) catheters are the primary method for draining ureters obstructed by malignancy and preventing a decline of the renal function. However, PCN-related infections such as pyelonephritis and urosepsis remain a significant concern. Currently no antimicrobial PCNs are available for preventing infectious complications. Vascular catheters impregnated with Minocycline/Rifampin (M/R) and M/R with Chlorhexidine coating (M/R+CHD) have previously demonstrated antimicrobial activity...
March 20, 2017: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/28302165/bilateral-adrenal-hemorrhage-in-the-background-of-escherichia-coli-sepsis-a-case-report
#14
Jahanzaib Khwaja
BACKGROUND: Sepsis is a syndrome of life-threatening organ dysfunction caused by a dysregulated host response to infection. It can have devastating consequences, including bilateral adrenal hemorrhage, particularly in patients at high thrombotic risk, such as those with antiphospholipid syndrome and those on long-term anticoagulation. CASE PRESENTATION: A 49-year-old white woman re-presented to hospital with a history suggestive of sepsis. She had a medical background of primary antiphospholipid syndrome on lifelong warfarin...
March 17, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28299763/the-efficacy-of-transrectal-ultrasound-guided-biopsy-versus-transperineal-template-biopsy-of-the-prostate-in-diagnosing-prostate-cancer-in-men-with-previous-negative-transrectal-ultrasound-guided-biopsy
#15
Shady Nafie, Michael Wanis, Masood Khan
PURPOSE: We have previously demonstrated that transperineal template prostate biopsy (TPTPB) has a significantly higher cancer detection rate compared to transrectal ultrasound guided (TRUS) biopsy in biopsy naive men with a PSA < 20 ng/mL. We, therefore, performed a prospective study to determine whether TPTPB is still superior to TRUS biopsy in the detection of prostate cancer in men with persistently elevated PSA after one previous negative set of TRUS biopsies. MATERIALS AND METHODS: 42 patients with a background of one previous negative set of TRUS biopsy, persistently elevated PSA (but < 20 ng/mL) and benign feeling digital rectal examination (DRE) underwent simultaneous standard 12-core TRUS biopsy and 36-core TPTPB under general anaesthesia...
March 16, 2017: Urology Journal
https://www.readbyqxmd.com/read/28292360/acute-on-chronic-liver-failure-causes-clinical-characteristics-and-predictors-of-mortality
#16
Abbas Ali Tasneem, Nasir Hassan Luck
OBJECTIVE: To determine the causes, characteristics and predictors of mortality in patients with acute-on-chronic liver failure (ACLF). STUDY DESIGN: Cross-sectional study. PLACE AND DURATION OF STUDY: Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi, from July 2014 to June 2016. METHODOLOGY: All patients with acute-on-chronic liver disease (ACLD) with ages > 12 were included...
January 2017: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28284886/role-of-coil-embolization-during-prostatic-artery-embolization-incidence-indications-and-safety-profile-%C3%A2
#17
Shivank Bhatia, Vishal Sinha, Matthew Bordegaray, Issam Kably, Sardis Harward, Govindarajan Narayanan
PURPOSE: To determine if coil embolization is a safe adjunctive measure to prevent nontarget embolization during prostatic artery embolization (PAE). MATERIALS AND METHODS: A retrospective analysis of patients who underwent PAE with coil embolization (cPAE) or without coil embolization (nPAE) between January 2014 and June 2016 was conducted. Adverse events, identified in accordance with SIR guidelines, and procedural variables were compared between the 2 cohorts...
May 2017: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/28160088/antibiotic-use-and-the-prevention-and-management-of-infectious-complications-in-stone-disease
#18
Daniel A Wollin, Adrian D Joyce, Mantu Gupta, Michael Y C Wong, Pilar Laguna, Stavros Gravas, Jorge Gutierrez, Luigi Cormio, Kunjie Wang, Glenn M Preminger
The importance of assessing perioperative urine/stone cultures and providing appropriate antibiotic prophylaxis prior to shock wave lithotripsy (SWL) or endoscopic intervention cannot be minimized. Urinary tract infection (UTI) is the most common complication relating to stone intervention. Adequate assessment of culture data and adherence to appropriate guidelines may prevent the development of UTI and the potential for post-intervention urosepsis. This review outlines the current evidence for prophylaxis in the prevention of UTI and urosepsis, as well as the interpretation of stone culture data to provide an evidence-based approach for the judicious use of antibiotics in urologic stone practice...
February 3, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28043312/ureteroscopy-for-management-of-ureteric-stones-in-children-a-single-centre-experience
#19
Nadeem Iqbal, Ijaz Hussain, Sehrish Waqar, Rizwana Sadaf, Ravale Tashfeen, Nur -Un- Nisa Nabil, Saeed Akhter
OBJECTIVE: To determine the outcomes of pediatric patients who underwent ureteroscopic removal of ureteric stones in terms of stone free rates and complications. STUDY DESIGN: Descriptive case series. PLACE AND DURATION OF STUDY: Urology Department at Shifa International Hospital, Islamabad, from January 2012 to December 2014. METHODOLOGY: A retrospective analysis of 37 patients, who underwent ureteroscopy for the treatment of ureteral calculi at the study centre, was conducted...
December 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28031194/azithromycin-ciprofloxacin-impregnated-urinary-catheters-avert-bacterial-colonization-biofilm-formation-and-inflammation-in-a-murine-model-of-foreign-body-associated-urinary-tract-infections-caused-by-pseudomonas-aeruginosa
#20
Hina Saini, Anitha Vadekeetil, Sanjay Chhibber, Kusum Harjai
Pseudomonas aeruginosa is a multifaceted pathogen causing a variety of biofilm-mediated infections, including catheter-associated urinary tract infections (CAUTIs). The high prevalence of CAUTIs in hospitals, their clinical manifestations, such as urethritis, cystitis, pyelonephritis, meningitis, urosepsis, and death, and the associated economic challenges underscore the need for management of these infections. Biomaterial modification of urinary catheters with two drugs seems an interesting approach to combat CAUTIs by inhibiting biofilm...
March 2017: Antimicrobial Agents and Chemotherapy
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