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https://www.readbyqxmd.com/read/28497089/impact-of-oral-capsule-of-peganum-harmala-on-alleviating-urinary-symptoms-in-men-with-benign-prostatic-hyperplasia-a-randomized-clinical-trial
#1
Majid Shirani-Boroujeni, Saeed Heidari-Soureshjani, Zahra Keivani Hafshejani
Introduction: Benign prostatic hyperplasia (BPH) is considered as a major cause of lower urinary tract symptoms (LUTS) in older men and its most common sign is nocturia. Objectives: This study aimed to determine the effect of the seeds of Peganum harmala compared with tamsulosin on alleviating urinary symptoms in patients with BPH. Patients and Methods: In this single blind clinical trial study, 90 patients diagnosed with BPH and LUTS, based on international prostate standard survey (IPSS) were divided into three groups...
2017: Journal of Renal Injury Prevention
https://www.readbyqxmd.com/read/28466585/efficacy-and-safety-of-combination-therapy-with-tamsulosin-dutasteride-and-imidafenacin-for-the-management-of-overactive-bladder-symptoms-associated-with-benign-prostatic-hyperplasia-a-multicenter-randomized-open-label-controlled-trial-direct-study
#2
Tomonori Yamanishi, Hirotaka Asakura, Narihito Seki, Shoji Tokunaga
OBJECTIVES: To evaluate the efficacy and safety of a combination therapy with dutasteride and imidafenacin in patients with benign prostatic hyperplasia and persistent overactive bladder symptoms. METHODS: A total of 163 patients presenting an enlarged prostate (volume >30 mL) and persistent overactive bladder symptoms despite at least 8 weeks of tamsulosin were randomized to receive tamsulosin and dutasteride, or tamsulosin, dutasteride and imidafenacin at a 1:1 ratio...
May 2, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28457310/unilateral-choroidal-detachment-following-the-use-of-tamsulosin
#3
Susanne M Lubbers, Wouter J Japing
No abstract text is available yet for this article.
April 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28424499/tamsulosin-for-treatment-of-lower-urinary-tract-symptoms-in-women-a-systematic-review-and-meta-analysis
#4
H L Zhang, Z G Huang, Y Qiu, X Cheng, X Q Zou, T T Liu
Tamsulosin has been used for the off-label treatment of lower urinary tract symptoms (LUTS) in women. Over the past few years, several randomized controlled trials (RCTs) have reported the clinical effectiveness and safety of tamsulosin for LUTS in women. Therefore, the aim of the present study was to perform a meta-analysis to evaluate the safety and efficacy of tamsulosin in treating LUTS in women, which may resolve some of the current controversies over use of the drug and provide more reliable evidence for the use of tamsulosin...
April 20, 2017: International Journal of Impotence Research
https://www.readbyqxmd.com/read/28410800/superparamagnetic-graphene-oxide-based-dispersive-solid-phase-extraction-for-preconcentration-and-determination-of-tamsulosin-hydrochloride-in-human-plasma-by-high-performance-liquid-chromatography-ultraviolet-detection
#5
Yaser Pashaei, Fatemeh Ghorbani-Bidkorbeh, Maryam Shekarchi
In the present study, superparamagnetic graphene oxide-Fe3O4 nanocomposites were successfully prepared by a modified impregnation method (MGOmi) and their application as a sorbent in the magnetic-dispersive solid phase extraction (M-dSPE) mode to the preconcentration and determination of tamsulosin hydrochloride (TMS) in human plasma was investigated by coupling with high performance liquid chromatography-ultraviolet detection (HPLC-UV). The structure, morphology and magnetic properties of the prepared nanocomposites were characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX), and vibrating sample magnetometry (VSM)...
March 19, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28409402/clinical-evaluation-of-tamsulosin-in-the-relief-of-lower-urinary-tract-symptoms-in-advanced-prostate-cancer-patients
#6
Tong Zhang, Haihu Wu, Shuai Liu, Wei He, Kejia Ding
PURPOSE: To assess the effectiveness and safety of tamsulosin combined with androgen deprivation therapy (ADT) for lower urinary tract symptoms (LUTS) in advanced prostate cancer (PC) patients. METHODS: Ninety PC patients with moderate-to-severe LUTS randomized into two groups of 45 each. One group received ADT (group 1), and the other received ADT plus tamsulosin (group 2) for 24 weeks. The outcome measures were changes in the International Prostate Symptom Score (IPSS), IPSS obstructive and irritative subscores, quality of life (QoL), maximum urinary flow rate (Q max), post-voiding residual (PVR) and prostate-specific antigen (PSA) from baseline...
April 13, 2017: International Urology and Nephrology
https://www.readbyqxmd.com/read/28384011/tadalafil-facilitates-the-distal-ureteral-stone-expulsion-a-meta-analysis
#7
Yunjin Bai, Yubo Yang, Xiaoming Wang, Yin Tang, Ping Han, Jia Wang
OBJECTIVE: To assess the efficacy and safety of tadalafil in facilitating the spontaneous passage of distal ureteral stones. METHODS: The relevant studies were identified by searching MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials up to November 2016. Randomized controlled trials evaluating effects of tadalafil for distal ureteral stones were included. RESULTS: Six publications involving 921 patients were included...
April 6, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28365782/role-of-silodosin-as-medical-expulsive-therapy-in-ureteral-calculi-a-meta-analysis-of-randomized-controlled-trials
#8
Xin-Jian Liu, Jian-Guo Wen, You-Dong Wan, Bo-Wen Hu, Qing-Wei Wang, Yan Wang
The objective of this study is to investigate the efficacy of silodosin in medical expulsive therapy (MET) for ureteral stones. We conducted a systematic review and meta-analysis to determine the efficacy and safety of silodosin in MET for ureteral calculi. We searched PubMed, Embase, Medline, Central (the Cochrane Library, Issue 1,2013), Google Scholar from the inception to March 2015 for randomized controlled trials (RCTs), comparing silodosin with tamsulosin or control on ureteral stone passage. Eight RCTs with a total of 1145 ureteral stone patients (300 patients in the control group, 287 patients in the tamsulosin group, 558 patients in the silodosin group) were included in this meta-analysis...
April 1, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28365198/-how-to-act-when-an-alpha-blocker-is-associated-with-a-potent-inhibitor-of-cyp3a4
#9
N Bensalah, S Garcia, F X Rose, P Bedouch, O Conort, M Juste, R Roubille, B Allenet, M Tod, B Charpiat
OBJECTIVE: Combination of alpha-blockers with potent CYP3A4 inhibitors is either contra-indicated or not recommended. We searched data supporting this classification and guiding prescribers when such an interaction occurs. METHODS: We analyzed reports published by the French agency for drug safety, reference books and performed search in databases of pharmacokinetics studies and case or case series related with these interactions. RESULTS: The classification of the potential severity of these interactions defined by the French agency for drug safety evolved over time...
March 29, 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28361519/evidence-is-enough-a-systematic-review-and-network-meta-analysis-of-the-efficacy-of-tamsulosin-0-2-mg-and-tamsulosin-0-4-mg-as-an-initial-therapeutic-dose-in-asian-benign-prostatic-hyperplasia-patients
#10
Su Jin Kim, In-Soo Shin, Sung-Jong Eun, Taeg-Keun Whangbo, Jin Wook Kim, Young Sam Cho, Joon Chul Kim
PURPOSE: We compared the efficacy of tamsulosin between 0.2 mg and 0.4 mg in Asian prostatic hyperplasia (BPH) patients using network meta-analysis due to lack of studies with direct comparison. METHODS: The literature search was conducted using the MEDLINE, Embase, and Cochrane Library. Keywords used were "BPH," "tamsulosin," "placebo." Experimental groups were defined as tamsulosin 0.2 mg (Tam 0.2) and 0.4 mg (Tam 0.4) and common control group was defined as placebo for indirect treatment comparison...
March 24, 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28344784/effects-of-tamsulosin-and-tolterodine-on-double-j-stent-related-symptoms-a-double-blind-randomized-placebo-controlled-trial
#11
Mahmoudreza Moradi, Hossein Abdi, Sina Ebrahimi, Haress Rezaee, Kaveh Kaseb
BACKGROUND: Ureteral double J stent are routinely applied for urologic patients although stent-related symptoms are common. Several attempts have been reported to minimize these symptoms. OBJECTIVE: To compare Tolterodine, Tamsulosin, and placebo effects on double J stent-related symptoms. MATERIAL AND METHOD: In all, 125 patients (82 males and 43 females) with double J stent were randomly divided into three groups (group 1, n: 42, group2, n: 40 and group 3, n: 43)...
2017: SAGE Open Medicine
https://www.readbyqxmd.com/read/28306333/efficacy-and-safety-of-naftopidil-in-the-medical-expulsion-therapy-for-distal-ureteral-stone-a-systematic-review-and-meta-analysis
#12
Jun Li, Zhuang Tang, Liang Gao, Jinhong Li, Feng Qin, Jiuhong Yuan
PURPOSE: The selective α-adrenoceptor blocker is widely used as a cost-effective treatment option for medical expulsive therapy (MET) of ureteral stones. In this review, we aimed to assess the efficacy and safety of naftopidil for MET compared with control or tamsulosin. METHODS: A systematic literature search was performed in PubMed, Cochrane Library, Embase, and Google Scholar to identify randomized controlled trials that compared naftopidil with either control or tamsulosin for the management of distal ureteral stones...
May 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28291706/medical-expulsive-therapy-use-in-emergency-department-patients-diagnosed-with-ureteral-stones
#13
Ralph C Wang, Newton Addo, Thomas Chi, Christopher Moore, Michael Mallin, Stephen Shiboski, Marshall Stoller, Rebecca Smith-Bindman
OBJECTIVE: Recent studies have clarified the role of alpha-blockers, such as tamsulosin, for patients diagnosed with ureteral stones <10mm not requiring an urgent intervention. Prior studies have reported low rates of use of MET by emergency physicians. We sought to describe patterns of alpha-blocker use and to determine factors associated with utilization in patients diagnosed with ureterolithiasis in the ED. METHODS: We used data from a randomized trial of CT scan vs...
February 28, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28275519/sildenafil-citrate-in-combination-with-tamsulosin-versus-tamsulosin-monotherapy-for-management-of-male-lower-urinary-tract-symptoms-due-to-benign-prostatic-hyperplasia-a-randomised-double-blind-placebo-controlled-trial
#14
Amr Fawzi, Mostafa Kamel, Emad Salem, Esam Desoky, Mohamed Omran, Hazem Elgalaly, Ahmed Sakr, Aref Maarouf, Salem Khalil
OBJECTIVE: To assess the additive effect of sildenafil citrate to tamsulosin in the treatment of lower urinary tract symptoms due to benign prostatic hyperplasia (LUTS/BPH) in men with or without erectile dysfunction (ED). PATIENTS AND METHODS: In all, 150 men with untreated LUTS/BPH with or without ED were randomised to receive sildenafil 25 mg once daily (OD) or placebo OD (night time) combined with tamsulosin 0.4 mg OD (day time) for 6 months. Changes from pre-treatment scores in International Prostate Symptom Score (IPSS), IPSS-quality of life (QoL) score, maximum urinary flow rate (Qmax), and the five-item version of the International Index of Erectile Function questionnaire (IIEF-5) were assessed at 3 and 6 months...
March 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/28261676/efficacy-of-phosphodiesterase-type-5-inhibitors-for-the-treatment-of-distal-ureteral-calculi-a-systematic-review-and-meta-analysis
#15
Carlos Eduardo Montes Cardona, Herney Andrés García-Perdomo
PURPOSE: To determine the efficacy of phosphodiesterase type 5 inhibitors (PDE5i) as medical expulsive therapy (MET) for the treatment of distal ureteral calculi. MATERIALS AND METHODS: A search strategy was conducted in the MEDLINE, CENTRAL, and Embase databases. Searches were also conducted in other databases and unpublished literature. Clinical trials were included without language restrictions. The risk of bias was evaluated with the Cochrane Collaboration's tool...
March 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28257560/dutasteride-add-on-therapy-reduces-detrusor-mass-in-patients-with-benign-prostatic-enlargement-not-satisfied-with-alpha-adrenergic-antagonist-monotherapy-a-single-center-prospective-study
#16
Cosimo De Nunzio, Aldo Brassetti, Flavia Proietti, Mauro Gacci, Sergio Serni, Francesco Esperto, Andrea Tubaro
AIMS: The ultrasound assessment of bladder wall thickness (BWT) and intravesical prostatic protrusion (IPP) have emerged as a non-invasive, inexpensive, time-saving alternatives to pressure-flow studies to assess benign prostatic obstruction (BPO). Aim of our study was to evaluate the effect on detrusor mass of dutasteride add-on therapy in men with lower urinary tract symptoms (LUTS) and benign prostatic enlargement (BPE). METHODS: A consecutive series of BPE patients with a prostate volume (PV) ≥30 mL and an international prostate symptoms score (IPSS) ≥8 not satisfied with Tamsulosin monotherapy were enrolled...
March 3, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28248054/-age-related-androgen-deficiency-and-benign-prostatic-hyperplasia-how-to-improve-the-rehabilitation-of-patients-after-transurethral-surgery
#17
A G Martov, D V Ergakov
RELEVANCE: Age-related androgen deficiency often coexists with benign prostatic hyperplasia (BPH), which requires surgical treatment. At the same time, severe lower urinary tract symptoms secondary to BPH are considered a relative contraindication to testosterone replacement therapy. The aim of this study was to evaluate the importance of correcting age-related androgen deficiency in patients with benign prostatic hyperplasia after transurethral operations. MATERIALS AND METHODS: The study comprised 60 patients with androgen deficiency (plasma testosterone levels below12...
December 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28247325/medical-expulsive-therapy-worthwhile-or-wishful-thinking
#18
REVIEW
Tad Kroczak, Kenneth T Pace, Jason Y Lee
PURPOSE OF REVIEW: We set out to provide an overview of the most recent evidence for medical expulsive therapy (MET). Conflicting level 1 evidence for and against the use of MET has been published. RECENT FINDINGS: The largest double-blind randomized control trial (1110 patients) comparing placebo, tamsulosin, and nifedipine found no benefit for MET in preventing the need for secondary intervention. A recent meta-analysis of 55 randomized trials using alpha-blockers suggests that no benefit is seen with smaller ureteric calculi, but patients with larger ureteric calculi experience shorter times to stone passage, fewer episodes of pain, require less surgical intervention, and fewer hospital admissions...
April 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28212471/-management-of-ureteric-colic-with-ketorolac-and-nifedipin-vs-ketorolac-and-tamsulosin-in-the-emergency-room
#19
Álvaro J Montiel-Jarquín, Valeria M Rocha-Rocha, Hugo A Solís-Mendoza, María S Romero-Figueroa, Ivet Etchegaray-Morales, Ivan Alvarado-Ortega
BACKGROUND: Ureteric colic is the most common symptom of lithiasis. It is caused by the presence of stones accumulated in the renal papillae. These stones often migrate down the ureter, causing a ureteric colic, characterized by a severe pain in the lumbar region. The aim of this study was to compare the use of ketorolac and nifedipine vs. ketorolac and tamsulosin for the medical treatment of pain caused by stones in the lower ureter. METHODS: Longitudinal study of 150 patients of 21-years or older with stones in the lower third of the ureter...
2017: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/28210174/anterior-segment-optical-coherence-tomography-changes-with-introduction-and-discontinuation-of-tamsulosin
#20
Abdullah Al-Kharashi, Amir A Azimzadeh, Jerry Leung, Sidney Radomski, Lenny Radomski, Wai-Ching Lam
PURPOSE: The aim of this study was to quantify changes and reversibility in pupil dilation and iris dilator muscle region thickness associated with introduction and subsequent discontinuation of tamsulosin in patients naïve to this drug with the aid of an anterior OCT system. METHODS: The study was carried out on 7 patients (14 eyes) naïve to tamsulosin and with benign prostatic hypertrophy (BHP). Measurements taken by Vistante OCT were done pre- and post-dilation of the following: pupil size, iris dilator muscle region (DMR) thickness, sphincter muscle region (SMR) thickness, and anterior chamber depth...
July 2016: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
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