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Bioresorbable scaffold

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https://www.readbyqxmd.com/read/28102777/comparison-of-early-vascular-morphological-changes-between-bioresorbable-poly-l-lactic-acid-scaffolds-and-metallic-stents-in-porcine-iliac-arteries
#1
Yasuhito Sekimoto, Hideaki Obara, Kentaro Matsubara, Naoki Fujimura, Hirohisa Harada, Yuko Kitagawa
Bioresorbable scaffolds have the potential to overcome several problems associated with metallic stents. Bioresorbable poly-L-lactic acid (PLLA) scaffold implantation for the treatment of peripheral artery disease has already been reported in animal models and clinical trials; however, no studies comparing PLLA scaffolds and bare metal stents (BMSs) with regard to early vascular morphological changes, identified using intravascular ultrasound (IVUS) analysis, have been reported. In this study, PLLA scaffolds and BMSs were implanted bilaterally in iliac arteries of five miniature pigs...
January 19, 2017: Organogenesis
https://www.readbyqxmd.com/read/28096169/correction-to-procedural-and-long-term-outcomes-of-bioresorbable-scaffolds-versus-drug-eluting-stents-in-chronic-total-occlusions-the-bonito-registry-bioresorbable-scaffolds-versus-drug-eluting-stents-in-chronic-total-occlusions
#2
https://www.readbyqxmd.com/read/28089777/bioresorbable-vascular-scaffold-to-treat-malignant-in-stent-restenosis-in-a-patient-with-nickel-allergy
#3
Alfonso Jurado-Román, María T López-Lluva, Ignacio Sánchez-Pérez, Jesús Piqueras-Flores, Ramón Maseda, Fernando Lozano-Ruíz-Poveda
Nickel is the most frequent allergen in patients with allergic contact dermatitis and nickel allergy has been associated with recurrent in-stent restenosis. However, it is often misdiagnosed because of a low suspicion threshold. It should be discarded in patients with recurrent in-stent restenosis, especially if their medical history reveals prior contact dermatitis. It is also noteworthy and rarely specified that even newer generation stents that use novel metal alloys also contain low amounts of nickel. To avoid the implantation of new stents containing this metal, when percutaneous coronary intervention is indicated, drug eluting balloons or bioresorbable vascular scaffolds associated with small doses of steroids could provide good alternatives of treatment...
January 2, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/28076449/long-term-follow-up-of-patients-after-percutaneous-coronary-intervention-with-everolimus-eluting-bioresorbable-vascular-scaffold
#4
Rafael Alexandre Meneguz-Moreno, José de Ribamar Costa, Freddy Antônio Britto Moscoso, Rodolfo Staico, Luiz Fernando Leite Tanajura, Marinella Patrizia Centemero, Auréa Jacob Chaves, Andrea Claudia Leão de Sousa Abizaid, Amanda Guerra de Moraes Rego E Sousa, Alexandre Antonio Cunha Abizaid
Background: Bioresorbable vascular scaffolds (BVS) were developed to improve the long-term results of percutaneous coronary intervention, restoring vasomotion. Objectives: To report very late follow-up of everolimus-eluting Absorb BVS (Abbott Vascular, Santa Clara, USA) in our center. Methods: Observational retrospective study, in a single Brazilian center, from August 2011 to October 2013, including 49 patients submitted to Absorb BVS implantation...
January 9, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28069611/bioresorbable-vascular-scaffolds-for-the-treatment-of-chronic-total-occlusions-an-international-multicenter-registry
#5
Satoru Mitomo, Toru Naganuma, Yusuke Fujino, Hiroyoshi Kawamoto, Sandeep Basavarajaiah, Michael Pitt, Wei-Hsian Yin, Damras Tresukosol, Antonio Colombo, Sunao Nakamura
BACKGROUND: There are only limited studies reporting clinical outcomes after bioresorbable vascular scaffold (BVS; Absorb; Abbott Vascular, Santa Clara, CA) implantation for coronary chronic total occlusions (CTO). The aim of this study was to evaluate the real-world feasibility and safety of BVS implantation for the treatment of CTO. METHODS AND RESULTS: We retrospectively evaluated CTO cases treated with BVS from a multicenter registry. The primary end point was target lesion failure defined as a composite of cardiac death, target vessel myocardial infarction, and clinically driven target lesion revascularization...
January 2017: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28057285/very-late-bioresorbable-vascular-scaffold%C3%A2-thrombosis-smoke-or-fire
#6
EDITORIAL
Fernando Alfonso, Javier Cuesta
No abstract text is available yet for this article.
January 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28057284/very-late-scaffold-thrombosis-of-bioresorbable-vascular-scaffold-systematic-review-and%C3%A2-a%C3%A2-meta-analysis
#7
Toshiaki Toyota, Takeshi Morimoto, Hiroki Shiomi, Yusuke Yoshikawa, Hidenori Yaku, Yugo Yamashita, Takeshi Kimura
OBJECTIVES: This study sought to compare the 2-year outcomes between bioresorbable vascular scaffold (BVS) and everolimus-eluting metallic drug-eluting stent (EES). BACKGROUND: The occurrence of very late stent/scaffold thrombosis (VLST) of BVS beyond 1 year after implantation is an increasing concern. METHODS: We conducted a meta-analysis of 24 studies (BVS: n = 2,567 and EES: n = 19,806) reporting the 2-year outcomes of BVS and/or EES to compare the risk of BVS versus EES for stent/scaffold thrombosis (ST) and target lesion failure (TLF) in 7 comparative studies (3 randomized and 4 observational), and to estimate the pooled incidence rates of ST and TLF including additional 17 single-arm studies...
January 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28045410/clinical-and-angiographic-outcomes-at-more-than-1-year-after-treatment-of-chronic-total-occlusions-with-the-everolimus-eluting-bioresorbable-vascular-scaffold
#8
Aylin Hatice Yamaç, Abdülkadir Yıldız, Meherrem Nasifov, Ahmet Taştan, Nemat Bashirov, Ömer Göktekin
OBJECTIVE: Treatment of chronic total occlusion (CTO) with everolimus-eluting bioresorbable vascular scaffold (BVS) is safe and effective at short-term follow-up (FU). The current study investigated clinical and angiographic outcomes after treatment of CTO with BVS at >1 year. METHODS: Thirty patients who underwent successful recanalization of 35 CTOs were included in this study. Quantitative coronary angiography (QCA) was performed at median FU period of 402 days...
December 2016: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28040446/first-evidence-of-complete-resorption-4%C3%A2-years-after-bioresorbable-scaffold-implantation-in-the-setting-of-st-segment%C3%A2-elevation%C3%A2-myocardial-infarction
#9
Tommaso Gori, Thomas Münzel
No abstract text is available yet for this article.
December 17, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28040440/persistent-bioresorbable-vascular-scaffold-by-optical-coherence-tomography-imaging-at-5-years
#10
Noriaki Moriyama, Koki Shishido, Kazuki Tobita, Takuma Takada, Tomoki Ochiai, Saori Tsukuda, Futoshi Yamanaka, Kazuya Sugitatsu, Shingo Mizuno, Yutaka Tanaka, Masato Murakami, Junya Matsumi, Saeko Takahashi, Takeshi Akasaka, Shigeru Saito
No abstract text is available yet for this article.
December 17, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28039591/visualizing-polymeric-bioresorbable-scaffolds-with-three-dimensional-image-reconstruction-using-contrast-enhanced-micro-computed-tomography
#11
Sheng Tu, Fudong Hu, Wei Cai, Liyan Xiao, Linlin Zhang, Hong Zheng, Qiong Jiang, Lianglong Chen
There are no previous studies showing how to visualize polymeric bioresorbable scaffolds (BRSs) by micro-computed tomography (mCT). There are no previous studies showing how to visualize polymeric bioresorbable scaffolds (BRSs) by micro-computed tomography (mCT). This study aimed to explore the feasibility of detecting polymeric BRS with 3-dimensional reconstruction of BRS images by contrast-enhanced mCT and to determine the optimal imaging settings. BRSs, made of poly-L-lactic acid (PLLA), were implanted in coronary bifurcation models...
December 30, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28038806/bioresorbable-coronary-stent-for-the-treatment-of-complex-coronary-lesions-data-from-an-all-comer-registry
#12
Andrea Cuculo, Antonio Ruggiero, Antonio Centola, Giulio Campanale, Tommaso Passero, Antonio Gaglione, Matteo Di Biase, Natale Daniele Brunetti
BACKGROUND: The study aimed to report the results from an all-comers registry of patients undergoing coronary angioplasty and treated with bioresorbable vascular scaffold (BVS). METHODS: Fifty-five consecutive patients with type B/C coronary lesions according to the AHA classification and treated with BVS were enrolled in the study. The clinical and procedural characteristics of enrolled patients were recorded. Fifty-five consecutive subjects with coronary lesions type B/C treated with everolimus eluting stent (EES) were used as control group...
December 19, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/28030655/percutaneous-coronary-intervention-with-bioresorbable-scaffolds-in-a-young-child
#13
Tamim M Nazif, Sanjog Kalra, Ziad A Ali, Dimitrios Karmpaliotis, Mariel E Turner, Thomas J Starc, Yang Cao, Charles C Marboe, Michael B Collins, Martin B Leon, Ajay J Kirtane
Importance: Although much less frequent than in adults, coronary artery disease requiring revascularization may develop in children because of homozygous familial hypercholesterolemia or other underlying conditions. Percutaneous coronary intervention (PCI) with a bioresorbable scaffold (BRS) may have advantages over metallic coronary stents in this population. Objective: To present a case of the successful treatment of unstable, multivessel coronary artery disease in a child with PCI with BRS implantation...
December 28, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/28025048/tropoelastin-inhibits-intimal-hyperplasia-of-mouse-bioresorbable-arterial-vascular-grafts
#14
Tadahisa Sugiura, Riddhima Agarwal, Shuhei Tara, Tai Yi, Yong-Ung Lee, Christopher K Breuer, Anthony S Weiss, Toshiharu Shinoka
: Neointimal hyperplasia, which results from the activation, proliferation and migration of vascular smooth muscle cells (SMCs), is a detrimental condition for vascular stents or vascular grafts that leads to stenosis. Preventing neointimal hyperplasia of vascular grafts is critically important for the success of arterial vascular grafts. We hypothesized that tropoelastin seeding onto the luminal surface of the graft would prevent neointimal hyperplasia through suppressing neointimal smooth muscle cell proliferation...
December 23, 2016: Acta Biomaterialia
https://www.readbyqxmd.com/read/28017314/coronary-artery-aneurysm-after-bioresorbable-vascular-scaffold-implantation-with-post-dilation-is-less-more
#15
Felix Meincke, Claudia Reinholz, Tobias Spangenberg, Hendrik Wienemann, Aref Arjomand, Felix Kreidel, Karl-Heinz Kuck, Alexander Ghanem
No abstract text is available yet for this article.
December 1, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28017311/efficacy-and-safety-of-the-absorb-everolimus-eluting-bioresorbable-scaffold%C3%A2-for-treatment-of-patients%C3%A2-with%C3%A2-diabetes-mellitus-results-of-the-absorb-diabetic-substudy
#16
Dean J Kereiakes, Stephen G Ellis, Takeshi Kimura, Alexandre Abizaid, Weiying Zhao, Susan Veldhof, Minh-Thien Vu, Zhen Zhang, Yoshinobu Onuma, Bernard Chevalier, Patrick W Serruys, Gregg W Stone
OBJECTIVES: The study sought to evaluate the efficacy and safety of the Absorb everolimus-eluting bioresorbable vascular scaffold (BVS) (Abbott Vascular, Abbott Park, Illinois) in patients with diabetes mellitus. BACKGROUND: Randomized, controlled trials have demonstrated comparable clinical outcomes following percutaneous coronary intervention with either Absorb BVS or metallic Xience everolimus-eluting stent. However, these trials lack power required to provide reliable treatment effect estimates in this high-risk population...
December 1, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28012050/comparative-assessment-of-plaque-media-change-on-three-modalities-of-ivus-immediately-after-implantation-of-either-everolimus-eluting-bioresorbable-vascular-scaffold-or-everolimus-eluting-metallic-stent-in-absorb-ii-study
#17
Yaping Zeng, Rafael Cavalcante, Erhan Tenekecioglu, Pannipa Suwannasom, Yohei Sotomi, Carlos Collet, Mahammad Abdelghani, Hans Jonker, Franck Digne, Dieter Horstkotte, Manfred Zehender, Ciro Indolfi, Francesco Saia, Rosario Fiorilli, Bernard Chevalier, Leonardo Bolognese, Javier Goicolea, Shaoping Nie, Yoshinobu Onuma, Patrick W Serruys
The purpose of the study to assess the comparability of immediate changes in plaque/media volume (PV) on three modalities of intravascular ultrasound (IVUS) after implantation of either bioresorbable vascular scaffold (BVS) or everolimus-eluting metallic stent (EES) in Absorb II Study. The two devices have different device volume and ultrasound backscattering that may interfere with the "plaque/media" assessed by three modalities on IVUS: grayscale, backscattering of radiofrequency and brightness function. In a multicenter randomized controlled trial, 501 patients with stable or unstable angina underwent documentary IVUS pre- and post- implantation...
December 23, 2016: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28008545/a-tri-leaflet-nitinol-mesh-scaffold-for-engineering-heart-valves
#18
S Hamed Alavi, Marc Soriano Baliarda, Noemi Bonessio, Lorenzo Valdevit, Arash Kheradvar
The epidemiology of valvular heart disease has significantly changed in the past few decades with aging as one of the main contributing factors. The available options for replacement of diseased valves are currently limited to mechanical and bioprosthetic valves, while the tissue engineered ones that are under study are currently far from clinical approval. The main problem with the tissue engineered heart valves is their progressive deterioration that leads to regurgitation and/or leaflet thickening a few months after implantation...
December 22, 2016: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28005110/biomechanics-of-polyhydroxyalkanoate-mesh-augmented-single-row-rotator-cuff-repairs
#19
Robert Z Tashjian, Christopher W Kolz, Thomas Suter, Heath B Henninger
Polyhydroxyalkanoate (PHA) mesh is a bioresorbable scaffold used to reinforce the suture-tendon interface in rotator cuff repairs (RCRs). We conducted a study of cyclic and ultimate failure properties of PHA mesh-augmented single-row RCRs and nonaugmented RCRs. Eight pairs of fresh-frozen cadaver humeri (6 male, 2 female) were tested. Mean (SD) age was 61 (9) years. The supraspinatus tendon was resected and reattached in a single-row configuration using 2 triple-loaded suture anchors and 6 simple stitches. The opposite humerus underwent RCR augmented with 2 strips of 13-mm × 23-mm PHA mesh...
November 2016: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28004209/sealing-of-calcified-plaques-after-bioresorbable-scaffold-implantations-a-five-year-follow-up
#20
Erhan Tenekecioglu, Christos V Bourantas, Yoshinobu Onuma, Patrick W Serruys
No abstract text is available yet for this article.
December 21, 2016: International Journal of Cardiovascular Imaging
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