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Bioresorbable scaffold

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https://www.readbyqxmd.com/read/29339714/stent-thrombosis-in-patients-with-drug-eluting-stents-and-bioresorbable-vascular-scaffolds-the-feared-complication
#1
Laura S Kerkmeijer, Erhan Tenekecioglu, Joanna J Wykrzykowska
The percutaneous coronary intervention has undergone rapid evolution over the last 40 years and has become one of the most widely performed medical procedures. The introduction of intracoronary stents improved the safety and efficacy of percutaneous coronary intervention. But with the advent of stenting, a new potentially fatal enemy emerged: stent thrombosis. Ever since, adjunct pharmacological therapy, stent technique and technology have been adjusted to reduce the risk of stent thrombosis. The aim of the present article is to provide an overview of past, present and future aspects of percutaneous intervention in relation to stent thrombosis...
January 15, 2018: Polish Archives of Internal Medicine
https://www.readbyqxmd.com/read/29332307/scaffold-thrombosis-following-implantation-of-the-absorb-bvs-in-routine-clinical-practice-insight-into-possible-mechanisms-from-optical-coherence-tomography
#2
Robin P Kraak, Alexandre H Kajita, Hector M Garcia-Garcia, Jose P S Henriques, Jan J Piek, E Karin Arkenbout, René J van der Schaaf, Jan G P Tijssen, Robbert J de Winter, Joanna J Wykrzykowska
OBJECTIVES: To identify potential underlying mechanisms of early and (very) late scaffold thrombosis (ScT) by optical coherence tomography (OCT), in a frame-by-frame analysis. BACKGROUND: The absorb scaffold is associated with an increased risk of ScT compared with metallic stents. Several potential causes of bioresorbable ScT have been identified, however the precise etiology still remains unclear. METHODS: Between February 2013 and February 2016, 13 patients presenting with definite ScT underwent OCT imaging...
January 14, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29327860/bioresorbable-scaffolds-versus-metallic-stents-in-routine-pci
#3
Robin P Kraak, Joanna J Wykrzykowska
No abstract text is available yet for this article.
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29327859/bioresorbable-scaffolds-versus-metallic-stents-in-routine-pci
#4
Ron Waksman
No abstract text is available yet for this article.
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29327858/bioresorbable-scaffolds-versus-metallic-stents-in-routine-pci
#5
Corrado Tamburino, Piera Capranzano
No abstract text is available yet for this article.
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29327857/bioresorbable-scaffolds-versus-metallic-stents-in-routine-pci
#6
Gian-Battista Danzi, Raffaele Piccolo
No abstract text is available yet for this article.
November 2, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29326154/what-happened-to-the-bioresorbable-scaffold-concept-black-tide-or-chernobyl
#7
EDITORIAL
Antoine Lafont, Marco G Mennuni
No abstract text is available yet for this article.
January 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29326152/decision-analytic-markov-model-weighting-expected-benefits-and-current-limitations-of-first-generation-bioresorbable-vascular-scaffolds-implications-for-manufacturers-and-next-device-iterations
#8
Davide Capodanno, Sergio Buccheri, Sara Romano, Piera Capranzano, Bruno Francaviglia, Corrado Tamburino
BACKGROUND: Relative benefits of bioresorbable vascular scaffolds (BVS) compared with everolimus-eluting stents (EES) are expected to accrue after complete bioresorption. METHODS AND RESULTS: We built a decision analytic Markov model comparing BVS and EES for a contemporary percutaneous coronary intervention population. Procedure-related morbidity and outcome data from the available literature were used to derive model probabilities. The net benefit of BVS and EES was estimated in terms of quality-adjusted life expectancy...
January 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29322695/bioresorbable-scaffolds-in-coronary-intervention-unmet-needs-and-evolution
#9
REVIEW
Davide Capodanno
Bioresorbable scaffolds (BRS) represent a novel paradigm in the 40-year history of interventional cardiology. Restoration of cyclic pulsatility and physiologic vasomotion, adaptive vascular remodeling, plaque regression, and removal of the trigger for late adverse events are expected BRS benefits over current metallic drug-eluting stents. However, first-generation BRS devices have significant manufacturing limitations and rely on optimal implantation technique to avoid experiencing an excess of clinical events...
January 2018: Korean Circulation Journal
https://www.readbyqxmd.com/read/29321399/where-are-the-secrets-of-increased-thrombosis-and-aneurysm-formation-with-the-current-bioresorbable-vascular-scaffolds-hidden-%C3%A3-reply
#10
Jeehoon Kang, Hyo-Soo Kim
No abstract text is available yet for this article.
January 11, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29321398/where-are-the-secrets-of-increased-thrombosis-and-aneurysm-formation-with-the-current-bioresorbable-vascular-scaffolds-hidden
#11
Nicholas G Kounis, Ioanna Koniari, Grigorios Tsigkas, George D Soufras, George Hahalis
No abstract text is available yet for this article.
January 11, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29310720/direct-comparison-of-coronary-bare-metal-vs-drug-eluting-stents-same-platform-different-mechanics
#12
Wolfram Schmidt, Peter Lanzer, Peter Behrens, Christoph Brandt-Wunderlich, Alper Öner, Hüseyin Ince, Klaus-Peter Schmitz, Niels Grabow
BACKGROUND: Drug-eluting stents (DES) compared to bare metal stents (BMS) have shown superior clinical performance, but are considered less suitable in complex cases. Most studies do not distinguish between DES and BMS with respect to their mechanical performance. The objective was to obtain mechanical parameters for direct comparison of BMS and DES. METHODS: In vitro bench tests evaluated crimped stent profiles, crossability in stenosis models, elastic recoil, bending stiffness (crimped and expanded), and scaffolding properties...
January 8, 2018: European Journal of Medical Research
https://www.readbyqxmd.com/read/29285611/process-induced-degradation-of-bioresorbable-pdlga-in-bone-tissue-scaffold-production
#13
H Little, S A Clarke, E Cunningham, F Buchanan
Process-induced degradation of clinically relevant resorbable polymers was investigated for two thermal techniques, filament extrusion followed by fused deposition modelling (FDM). The aim was to develop a clear understanding of the relationship between temperature, processing time and resultant process-induced degradation. This acts to address the current knowledge gap in studies involving thermal processing of resorbable polymers. Poly(DL-lactide-co-glycolide) (PDLGA) was chosen for its clinically relevant resorption properties...
December 28, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/29284158/optimized-polymer-coating-for-magnesium-alloy-based-bioresorbable-scaffolds-for-long-lasting-drug-release-and-corrosion-resistance
#14
Wei Xu, Kai Yagoshi, Yuki Koga, Makoto Sasaki, Takuro Niidome
Magnesium (Mg) alloy-based bioresorbable scaffolds (BRSs) are attracting interest as next-generation stents. However, because medical Mg alloy materials degrade relatively quickly in physiological media, surface corrosion protection via biodegradable polymer coatings is important for clinical applications. Herein, the influence of biodegradable polymer coatings on the BRS corrosion was investigated. First, elution of the drug sirolimus (SRL) from various biodegradable polymers was estimated, including poly(d,l-lactic acid) (PDLLA), poly(d,l-lactic acid-co-ε-caprolactone) (PLCL) and poly(ε-caprolactone) (PCL)...
December 19, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29281608/a-new-generation-of-drug-eluting-stents-indications-and-outcomes-of-bioresorbable-vascular-scaffolds
#15
REVIEW
Ron Waksman
Drug-eluting stents (DES) are increasingly being used as a less invasive alternative to coronary artery bypass grafting. Early generation DES had durable polymers that provided acceptable efficacy outcomes but had high rates of stent thrombosis leading to myocardial infarction and death. Second-generation DES have improved outcomes by reducing stent thrombosis and recurrent stenosis. Newer DES with biodegradable polymers have similar efficacy as second-generation DES, but have higher rates of stent thrombosis...
December 2017: Cleveland Clinic Journal of Medicine
https://www.readbyqxmd.com/read/29278353/long-term-safety-of-bioresorbable-scaffolds-insights-from-a-network-meta-analysis-including-91-trials
#16
Si-Hyuck Kang, Bill D Gogas, Ki-Hyun Jeon, Jie-Suck Park, Wonjae Lee, Chang-Hwan Yoon, Jung-Won Suh, Seung-Sik Hwang, Tae-Jin Youn, In-Ho Chae, Hyo-Soo Kim
AIMS: To investigate the long-term safety and efficacy of biodegradable scaffolds and metallic stents. METHODS AND RESULTS: We analyzed a total of 91 randomized controlled trials with a mean follow-up of 3.7 years in 105,842 patients which compared 2 or more coronary metallic stents or biodegradable scaffolds and reported the long-term clinical outcomes (≥2 years). Network meta-analysis showed that patients treated with the Absorb bioresorbable vascular scaffold (BVS) had significantly higher risk of definite or probable scaffold thrombosis (ScT) compared to those treated with metallic DES...
December 26, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29277145/long-term-intravascular-follow-up-of-coronary-bifurcation-treatment-with-absorb-bioresorbable-vascular-scaffold
#17
Maarten Vanhaverbeke, Keir McCutcheon, Christophe Dubois, Johan Bennett
No abstract text is available yet for this article.
December 25, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/29276441/bioresorbable-scaffolds-in-spontaneous-coronary-artery-dissection-long-term-follow-up-in-4-patients
#18
Santiago Jesús Camacho Freire, Antonio Enrique Gómez Menchero, Jessica Roa Garrido, Javier León Jiménez, Rosa Cardenal Piris, José Francisco Díaz Fernández
Spontaneous coronary artery dissection is a rare condition, and diagnosis and treatment are challenging among patients who present with acute coronary syndrome. Typically, the condition affects young females who have no underlying atherosclerotic disease. To date, few cases of bioresorbable scaffold implantation for the treatment of spontaneous coronary artery dissection have been reported. Therefore, we describe the cases of 4 patients whom we treated with scaffolds. We evaluated the long-term results by using intravascular ultrasound and optical coherence tomographic scanning...
December 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/29260716/data-from-real-world-registries-can-it-guide-development-of-the-bioresorbable-scaffolds-of-tomorrow
#19
Salvatore Brugaletta, Luis Ortega-Paz, Yoshinobu Onuma
No abstract text is available yet for this article.
December 20, 2017: EuroIntervention
https://www.readbyqxmd.com/read/29247976/coronary-calcification-as-a-mechanism-of-plaque-media-shrinkage-in-vessels-treated-with-bioresorbable-vascular-scaffold-a-multimodality-intracoronary-imaging-study
#20
Yaping Zeng, Rafael Cavalcante, Carlos Collet, Erhan Tenekecioglu, Yohei Sotomi, Yosuke Miyazaki, Yuki Katagiri, Taku Asano, Mohammad Abdelghani, Shaoping Nie, Christos V Bourantas, Nico Bruining, Yoshinobu Onuma, Patrick W Serruys
BACKGROUND AND AIMS: Whether coronary calcification is correlated with plaque/media shrinkage (PS) remains unclear. The aim of this study was to assess the relationship between the calcification process and PS, combining serial optical coherence tomography (OCT) and intravascular ultrasound (IVUS) in vessels treated with bioresorbable vascular scaffolds (BVS). METHODS: In 15 patients (16 vessels), OCT and IVUS images were matched using anatomic landmarks at post-procedure and five years...
December 2, 2017: Atherosclerosis
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