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https://www.readbyqxmd.com/read/29160058/unraveled-face-dependent-effects-of-multi-layered-graphene-embedded-in-transparent-organic-light-emitting-diodes
#1
Jong Tae Lim, Jaesu Kim, Hyunkoo Lee, Jaehyun Moon, Byoung-Hwa Kwon, Seongdeok Ahn, Nam Sung Cho, Byung-Wook Ahn, Jeong-Ik Lee, Kyuwook Ihm, Seong Chu Lim
With increasing demand for transparent conducting electrode, graphene has attracted considerable attention, owing to its high electrical conductivity, high transmittance, low reflectance, flexibility and tunable work function. Two faces of single layer graphene are indistinguishable in its nature and this idea has not been doubted even in multilayered graphene (MLG) because it is difficult to separately characterize the front (first-born) and rear face (last-born) of MLG by using conventional analysis tools, such as Raman, ultraviolet spectroscopy, scanning probe microscopy, and sheet resistance...
November 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29157917/the-mediator-complex-in-genomic-and-non-genomic-signaling-in-cancer
#2
Hannah Weber, Michael J Garabedian
Mediator is a conserved, multi-subunit macromolecular machine divided structurally into head, middle, and tail modules, along with a transiently associating kinase module. Mediator functions as an integrator of transcriptional regulatory activity by interacting with DNA-bound transcription factors and with RNA polymerase II (Pol II) to both activate and repress gene expression. Mediator has been shown to affect multiple steps in transcription, including chromatin looping between enhancers and promoters, pre-initiation complex formation, transcriptional elongation, and mRNA splicing...
November 17, 2017: Steroids
https://www.readbyqxmd.com/read/29154747/disseminated-methicillin-susceptible-staphylococcus-aureus-infection
#3
David R Perkins, James A Hall, Lisa M Lopez, Lizbeth Janice Cahuayme-Zuniga
INTRODUCTION: When clinicians think about Staphylococcus aureus bacteria, what comes to the mind of most is the dreaded methicillin-resistant form. However, clinicians should not forget the methicillin-susceptible type, which is just as virulent. CASE PRESENTATION: The authors present the case of a 20-year-old woman who was admitted with septic shock and multi-organ failure and was found to have disseminated methicillin-susceptible Staphylococcus aureus (MSSA) infection...
November 20, 2017: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29151063/predation-among-microorganisms-a-huge-potential-of-interspecies-dependencies
#4
Justyna Kowalska, Marcin Włodarczyk
There are many interactions between species (including bacteria) in the environment. One of them is predation, which always leads to the death of a prey. Described in this review Bdellovibrio bacteriovorus (Deltaproteobacteria) and Micavibrio aeruginosavorus (Alfaproteobacteria) are uniflagellate, rod shaped and curved obligate predators of Gram-negative bacteria. Both species belong to the group of BALOs (Bdellovibrio and like organisms). B. bacteriovorus use periplasmic predatory strategy and M. aeruginosavorus are epibiotic hunters...
November 3, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/29150378/enhanced-antibacterial-effects-of-green-synthesized-zno-nps-using-aristolochia-indica-against-multi-drug-resistant-bacterial-pathogens-from-diabetic-foot-ulcer
#5
Katherin Steffy, G Shanthi, Anson S Maroky, S Selvakumar
BACKGROUND: Increased incidence of Multi-drug resistance in microorganisms has become the greatest challenge in the treatment of Diabetic Foot Ulcer (DFU) and urges the need of a new antimicrobial agent. In this study, we determined the bactericidal effects of ZnO nanoparticles (ZnO NPs) green synthesized from Aristolochia indica against Multi-drug Resistant Organisms (MDROs) isolated from pus samples of DFU patients attending in a tertiary care hospital in South India. METHODS: ZnO NPs were characterized by UV-vis-DRS spectroscopy, Atomic Force Microscopy (AFM), Transmission Electron Microscopy (TEM) and for its zeta potential value...
November 14, 2017: Journal of Infection and Public Health
https://www.readbyqxmd.com/read/29142104/constraints-on-lateral-gene-transfer-in-promoting-fimbrial-usher-protein-diversity-and-function
#6
Christopher J Stubenrauch, Gordon Dougan, Trevor Lithgow, Eva Heinz
Fimbriae are long, adhesive structures widespread throughout members of the family Enterobacteriaceae. They are multimeric extrusions, which are moved out of the bacterial cell through an integral outer membrane protein called usher. The complex folding mechanics of the usher protein were recently revealed to be catalysed by the membrane-embedded translocation and assembly module (TAM). Here, we examine the diversity of usher proteins across a wide range of extraintestinal (ExPEC) and enteropathogenic (EPEC) Escherichia coli, and further focus on a so far undescribed chaperone-usher system, with this usher referred to as UshC...
November 2017: Open Biology
https://www.readbyqxmd.com/read/29137627/prevalence-of-current-patterns-and-predictive-trends-of-multidrug-resistant-salmonella-typhi-in-sudan
#7
Ayman A Elshayeb, Abdelazim A Ahmed, Marmar A El Siddig, Adil A El Hussien
BACKGROUND: Enteric fever has persistence of great impact in Sudanese public health especially during rainy season when the causative agent Salmonella enterica serovar Typhi possesses pan endemic patterns in most regions of Sudan - Khartoum. OBJECTIVES: The present study aims to assess the recent state of antibiotics susceptibility of Salmonella Typhi with special concern to multidrug resistance strains and predict the emergence of new resistant patterns and outbreaks...
November 14, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29137578/predictive-value-of-quick-sepsis-related-organ-failure-scores-following-sepsis-related-medical-emergency-team-calls-a-retrospective-cohort-study
#8
D Boulos, Y Shehabi, J A Moghaddas, M Birrell, A Choy, V Giang, J Nguyen, T Hall, S Le
We conducted a cohort study of adult ward patients who had a Medical Emergency Team (MET) call triggered by confirmed or suspected sepsis in an Australian tertiary centre to assess the predictive utility of systemic inflammatory response syndrome (SIRS) and quick Sepsis-Related Organ Failure Assessment (qSOFA) scores for 28-day mortality over a 12-month period. Sepsis was the causative aetiology in 970 MET calls for 646 patients with a mean age of 68 years and median Charlson Comorbidity score (CCS) of 3.0...
November 2017: Anaesthesia and Intensive Care
https://www.readbyqxmd.com/read/29133186/a-novel-protocol-for-contact-isolation-for-multi-drug-resistant-organisms-mdros-in-children-on-inpatient-rehabilitation-and-effects-on-functional-outcomes-a-noninferiority-study
#9
Kelly L D Pham, Kristie F Bjornson, Marisa Osorio, Kathryn B Whitlock, Teresa L Massagli
BACKGROUND: The incidence of contact isolation for multidrug resistant organisms is increasing in acute hospitals and inpatient rehabilitation units alike. There is limited evidence on the effect of contact isolation on functional outcomes during inpatient rehabilitation. OBJECTIVE: To determine whether the use of a modified contact isolation protocol (MCI) resulted in non-inferior functional outcomes compared to children without contact isolation (NCI) on inpatient rehabilitation...
November 10, 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29128604/influence-of-maternal-age-on-the-effects-of-seleno-l-methionine-in-the-model-organism-daphnia-pulex-under-standard-and-heat-stress-conditions
#10
Jordan R Nelson, Tonia S Schwartz, Julia M Gohlke
Selenium deficiency and toxicity increase the risk of adverse developmental and reproductive outcomes; however, few multi-stressor studies have evaluated the influence of maternal age on organic selenium dose-response and additional stressors over the life course. While multi-stressor research in mammalian models is time-consuming and expensive, use of alternative models can efficiently produce screening data for prioritizing research in mammalian systems. As a well-known eco-toxicological model, Daphnia pulex, may offer advantages in screening for impacts of multi-stressor exposures...
November 8, 2017: Reproductive Toxicology
https://www.readbyqxmd.com/read/29119059/the-bacteriological-profile-of-the-burned-patients-in-the-center-of-burns-in-chu-mohamed-vi-marrakech-about-123-cases
#11
Yassine Benchamkha, Ouafaa Dhaidah, Adil Dahazze, Quaboul Meriem, Moulay Driss Elamrani, Salwa Ettalbi
The bacterial nosocomial infection is one of the leading causes of morbidity and mortality for burned patient; we conducted a retrospective study of 123 patients hospitalized in the burns center CHUMED VI of Marrakechover a period of 3 years, from January 1(st), 2013 to December 31(st), 2016. The criteria for nosocomial infection were those of the Center for Disease Control in Atlanta in 1988. Incidence rates were calculated. The bacterial ecology of the department was described as also antibiotype. The predominancy of the population was male...
2017: International Journal of Burns and Trauma
https://www.readbyqxmd.com/read/29111434/empiric-treatment-of-lower-urinary-tract-infections-in-the-face-of-spreading-multi-drug-resistance-in-vitro-study-of-nitroxoline-effectiveness
#12
A Sobke, O Makarewicz, M Baier, C Bär, W Pfister, S G Gatermann, M W Pletz, C Forstner
The spread of antimicrobial resistance challenges the empiric treatment in urinary tract infections (UTI). Among others, nitrofurantoin is recommended for first line treatment, but acceptance among clinicians is limited due to chronic nitrofurantoin-induced lung toxicity and insufficient coverage of Enterobacteriaceae other than Escherichia coli. Nitroxoline seems to be an alternative to nitrofurantoin due to its favourable safety profile but data on its current in vitro susceptibility are sparse. In this study susceptibility to nitroxoline was tested against 3,012 urinary clinical isolates (including multidrug-resistant bacteria and Candida spp...
October 27, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29110374/towards-understanding-the-mechanisms-of-actions-of-ceacam6-in-cancer-progression
#13
REVIEW
Balsam Rizeq, Zain Zakaria, Allal Ouhtit
Human carcinoembryonic antigen (CEA) is the prototypic member of highly related cell surface glycoproteins that includes Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) and others. CEACAM6 (formerly NCA) that belongs to the immunoglobulin superfamily, is a cell adhesion proteins of the CEA family. It is normally expressed on the epithelial surfaces and the surface of myeloid (CD66c). CEACAM6 is a multi-functional glycoprotein that mediates homotypic binding with other CEA family members and heterotypic binding with integrin receptors...
November 7, 2017: Cancer Science
https://www.readbyqxmd.com/read/29103699/salmonella-spp-and-listeria-monocytogenes-shedding-in-domestic-ruminants-and-characterization-of-potentially-pathogenic-strains
#14
Ana Hurtado, Medelin Ocejo, Beatriz Oporto
Salmonella and Listeria monocytogenes are important human pathogens that can be isolated from the faeces of ruminants, and constitute potential sources of human infection via contamination of food and water or contact (direct or indirect) between humans and animals. A cross-sectional survey including 301 herds was carried out to estimate the prevalence of cattle herds (beef and dairy) and sheep flocks positive for these zoonotic organisms in ruminants in the Basque Country (Northern Spain). The proportion of herds where Salmonella shedding was detected was 5...
October 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/29103679/testing-cathelicidin-susceptibility-of-bacterial-mastitis-isolates-technical-challenges-and-data-output-for-clinical-isolates
#15
Melissa N Langer, Stefanie Blodkamp, Martin Bayerbach, Andrea T Feßler, Nicole de Buhr, Thomas Gutsmann, Lothar Kreienbrock, Stefan Schwarz, Maren von Köckritz-Blickwede
Bovine mastitis caused by bacterial pathogens, such as Staphylococcus (S.) aureus and Escherichia (E.) coli, is a major economic problem in dairy industry. In order to limit the presence of multi-resistant bacteria in bovine mastitis, alternatives for the treatment with antibiotics are urgently needed. Antimicrobial peptides (AMPs) have recently been discussed as a potential new strategy against bacterial infections. They are key players in the innate immune system, as they can directly act against microorganisms or modulate the immune system...
October 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/29103599/three-dimensional-discrete-element-method-for-the-prediction-of-protoplasmic-seepage-through-membrane-in-a-biological-cell
#16
Kelvin K L Wong
This paper presents a three-dimensional and compressible biological cell model based on discrete element method using multiple interacting agent that represent cellular structures within a simulated environment. The cytoplasm and nucleoplasm fluid behavior in the cell is time dependent. When taking this approach, it is important to calibrate protoplasmic flow behaviors through simulation techniques such as compressing the cell and examining the agents representing the cell cytoplasm seeping between the ones representing the confining cell membrane...
October 25, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29103080/first-report-of-neonatal-early-onset-sepsis-caused-by-multi-drug-resistant-raoultella-ornithinolytica
#17
Asad Abbas, Istiyaq Ahmad
Raoultella ornithinolytica is increasingly being isolated as a causative organism in human infections. Most of the infections caused by R. ornithinolytica are hospital acquired and occur in patients who are immunocompromised, had invasive procedures or have indwelling catheters. This is a first report of early onset neonatal sepsis caused by multi-drug-resistant R. ornithinolytica. The infection was not very severe and was characterised by generalized flushing of the skin. Patient made complete recovery once appropriate antibiotics were started...
November 4, 2017: Infection
https://www.readbyqxmd.com/read/29097343/molecular-detection-of-multi-drug-resistant-mycobacterium-leprae-from-indian-leprosy-patients
#18
Mallika Lavania, Itu Singh, Ravindra P Turankar, Madhvi Ahuja, Vinay Pathak, Utpal Sengupta, Loretta Das, Archana Kumar, Joydeepa Darlong, Rajeev Nathan, Asha Maseey
OBJECTIVE: Emergence of multi drug resistant (MDR) organism for any infectious disease is a public health concern. Global efforts to control leprosy by intensive chemotherapy have led to a significant decrease in the number of registered patients. Currently recommended control measures for treating leprosy with MDT was designed to prevent the spread of dapsone resistant strains of Mycobacterium leprae. We report here the identification of MDR strains of M. leprae from relapsed leprosy patients from endemic regions in India...
October 30, 2017: Journal of Global Antimicrobial Resistance
https://www.readbyqxmd.com/read/29096346/intraabdominal-abscess-caused-by-stenotrophomonas-maltophilia-a-case-report
#19
Toyomitsu Sawai, Sumako Yoshioka, Nobuko Matsuo, Naofumi Suyama, Hiroshi Mukae
INTRODUCTION: Stenotrophomonas maltophilia usually causes nosocomial infections, but intraabdominal abscesses or organ/space surgical site infection (SSI) secondary to this organism has been rarely reported. Here, we reported a rare case of SSI that presented as intraabdominal abscess caused by S. maltophilia. PRESENTATION OF CASE: A 68-year-old woman presented to our hospital with transverse colon cancer. Further work up with abdominal computed tomography (CT) revealed left renal cell carcinoma...
October 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29081854/toxic-shock-in-children-with-bone-and-joint-infections-a-review-of-seven-years-of-patients-admitted-to-one-intensive-care-unit
#20
D L Kerr, E K Loraas, A C Links, T V Brogan, G A Schmale
PURPOSE: The objective of this study was to compare the frequency of severe systemic, multi-organ involvement and toxic shock syndrome (TSS) in patients with Staphylococcus aureus (SA) and Group A β-haemolytic Streptococcus pyogenes (GABS) bone and joint infections. METHODS: We retrospectively reviewed patients treated for septic arthritis or osteomyelitis at one children's hospital between 2002 and 2009. The rates of intensive care unit (ICU) admission for methicillin-sensitive SA (MSSA), methicillin-resistant SA (MRSA) and GABS infections were compared, as were the lengths of stay, number of surgeries, operative procedures and cases of TSS...
October 1, 2017: Journal of Children's Orthopaedics
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