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https://www.readbyqxmd.com/read/29426291/paediatric-pancreaticobiliary-endoscopy-a-21-year-experience-from-a-tertiary-hepatobiliary-centre-and-systematic-literature-review
#1
Margaret G Keane, Mayur Kumar, Natascha Cieplik, Douglas Thorburn, Gavin J Johnson, George J Webster, Michael H Chapman, Keith J Lindley, Stephen P Pereira
BACKGROUND: In adults ERCP and endoscopic ultrasound (EUS) are standard methods of evaluating and treating many hepatopancreaticobiliary (HPB) conditions. HPB disease is being diagnosed with increasing frequency in children but information about role of ERCP and EUS and their outcomes in this population remain limited. Therefore the aims of this study were to describe the paediatric ERCP and EUS experience from a large tertiary referral HPB centre, and to systematically compare outcomes with those of other published series...
February 9, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29422634/biogenic-corrosion-inhibitor-on-mild-steel-protection-in-concentrated-hcl-medium
#2
Muthukumar Krishnan, Harinee Subramanian, Hans-Uwe Dahms, Vignesh Sivanandham, Palanichamy Seeni, Subramanian Gopalan, Ashok Mahalingam, Arthur James Rathinam
Turbinaria ornata (TO) extract was tested as green corrosion inhibitor on mild steel (MS) coupons in conc. HCl medium with an efficiency of 100% at 25 g l-1 during 5 min exposure. Antibacterial efficacy performed against 16 S rDNA identified marine biofilming bacteria (MBB) and human pathogenic bacteria (HPB). Maximum inhibition growth was 16 mm on MBB observed in Bacillus megaterium (MBF14 - AB894827) and 20 mm on HPB in Escherichia coli (B5 - NCIM 2931). Similarly, minimum of 10 mm on MBB witnessed in Pseudomonas sp...
February 8, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29381892/methodology-effects-on-determining-the-energy-concentration-and-the-apparent-total-tract-digestibility-of-components-in-diets-fed-to-growing-pigs
#3
Chengfei Huang, Ping Li, Xiao Kang Ma, Neil William Jaworski, Hans Henrik Stein, Chang Hua Lai, Jin Biao Zhao, Shuai Zhang
Objective: An experiment was conducted to investigate the effects of different diet formulations: F1 (Two complicated basal diets containing different CP levels plus tested feedstuff) vs F2 (A simple corn soybean meal basal diet plus tested feedstuff) combined with total collection (TC) or chromic oxide (Cr2O3) marker or acid-insoluble ash (AIA) marker method, and freeze-dry (FD) or oven-dry (OD) technique on estimation of nutrient digestibility in diets fed to growing pigs. Methods: In F1, twelve barrows were allocated to two 6 × 4 Youden Squares...
January 26, 2018: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/29353674/a-novel-3d-heteropoly-blue-type-photo-fenton-like-catalyst-and-its-ability-to-remove-dye-pollution
#4
Bao-Li Fei, Jian-Kai Zhong, Ni-Ping Deng, Jiang-Hong Wang, Qing-Bo Liu, Yang-Guang Li, Xiang Mei
A environment-friendly 3D inorganic heteropoly blue (HPB) Ba2Na2 [HPWV4WVI8O40]·26H2O was directly synthesized by hydrothermal method and characterized by means of ICP, IR, XPS, X-ray single crystal and X-ray powder diffraction. It was an efficient heterogeneous photo-Fenton-like catalyst to degrade anionic dye methyl orange under visible light irradiation. It removed cationic dyes methylene blue in neutral environment and rhodamine B in acidic condition via flocculation. The removal efficiency of methylene blue and rhodamine B by flocculation was more than 95%...
January 12, 2018: Chemosphere
https://www.readbyqxmd.com/read/29340728/indocyanine-green-retention-rates-at-15%C3%A2-min-predicted-hepatic-decompensation-in-a-western-population
#5
Bertrand Le Roy, Emilie Grégoire, Cyril Cossé, Badr Serji, Nicolas Golse, René Adam, Daniel Cherqui, Jean-Yves Mabrut, Yves-Patrice Le Treut, Eric Vibert
BACKGROUND: ICGR15 is widely used in Asia to evaluate the liver reserve before hepatectomy, but not in Western countries where patients are selected using the MELD score and/or platelet count. Postoperative liver failure is rare nowadays, but hepatic decompensation (HD), defined by 3-month postoperative ascites, impairs quality of life and survival. The aim of this study was to evaluate the relevance of indocyanine green retention rate at 15 min (ICGR15) before liver resection in Western countries, in order to predict HD...
January 16, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29318905/multiparametric-mri-for-early-detection-of-diffuse-liver-disease-an-interview-with-david-breen
#6
David J Breen
David J Breen is Associate Professor of Radiology and previous Clinical Director of Radiology at University Hospital Southampton. His interests are in abdominal imaging and intervention, particularly of hepato-pancreato-biliary (HPB)and renal disease. He has a major interest in image-guided tumor ablation and improving outcomes from these procedures. He has previously served as Vice Chair of the NHS England Clinical Reference Group in Interventional Radiology and for the NIHR/NCRN Upper GI Clinical Studies Group...
January 10, 2018: Biomarkers in Medicine
https://www.readbyqxmd.com/read/29304787/factors-associated-with-prolonged-length-of-stay-for-elective-hepatobiliary-and-neurosurgery-patients-a-retrospective-medical-record-review
#7
Siu Yin Lee, Soo-Hoon Lee, Jenny H H Tan, Howard S L Foo, Phillip H Phan, Alfred W C Kow, Sein Lwin, Penelope M Y Seah, Siti Zubaidah Mordiffi
BACKGROUND: Patients with prolonged length of hospital stay (LOS) not only increase their risks of nosocomial infections but also deny other patients access to inpatient care. Hepatobiliary (HPB) malignancies have some of highest incidences in East and Southeast Asia and the management of patients undergoing HPB surgeries have yet to be standardized. With improved neurosurgery techniques for intracranial aneurysms and tumors, neurosurgeries (NS) can be expected to increase. Elective surgeries account for far more operations than emergencies surgeries...
January 5, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29288741/optimization-of-washing-conditions-with-biogenic-mobilizing-agents-for-marine-fuel-contaminated-beach-sands
#8
Alessia Arelli, Andrea Nuzzo, Claudia Sabia, Ibrahim M Banat, Giulio Zanaroli, Fabio Fava
Washing is a rapid and effective treatment to remediate contaminated sands impacted by oil spills, although synthetic additives used to increase extraction efficiency may cause additional pollution issues due to their intrinsic toxicity and very often low biodegradability. In this study, different biogenic mobilizing agents (soybean lecithins, cyclodextrins, cholic acids, plant-derived cleaners, rhamnolipids and sophorolipids) were tested in the washing of beach sands artificially contaminated with the Intermediate Fuel Oil IFO-180...
December 27, 2017: New Biotechnology
https://www.readbyqxmd.com/read/29287736/prospective-evaluation-of-the-international-study-group-for-liver-surgery-definition-of-post-hepatectomy-liver-failure-after-liver-resection-an-international-multicentre-study
#9
Asma Sultana, Mark Brooke-Smith, Shahid Ullah, Joan Figueras, Myrddin Rees, Jean-Nicolas Vauthey, Claudius Conrad, Thomas J Hugh, O James Garden, Sheung T Fan, Michael Crawford, Masatoshi Makuuchi, Yukihiro Yokoyama, Markus Büchler, Robert Padbury
BACKGROUND: The International Study Group for Liver Surgery (ISGLS) definition of post hepatectomy liver failure (PHLF) was developed to be consistent, widely applicable, and to include severity stratification. This international multicentre collaborative study aimed to prospectively validate the ISGLS definition of PHLF. METHODS: 11 HPB centres from 7 countries developed a standardised reporting form. Prospectively acquired anonymised data on liver resections performed between 01 July 2010 and 30 June 2011 was collected...
December 26, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29281197/smoking-cessation-program-among-naval-diver-trainees-in-the-republic-of-singapore-navy
#10
Jake Jk Goh
BACKGROUND: Since 2016, the Naval Diving Unit (NDU) of the Republic of Singapore Navy (RSN) has instituted a smoking cessation trial program for their trainees, instituting a blanket ban on smoking during training hours in order to promote smoking cessation and create a smoke-free culture among its servicemen. For the rest of RSN personnel, they would attend a more costly, established Health Promotion Board (HPB) smoking cessation program, which employs social support strategies, while they undergo basic training in the Navy Military Experts Institute (NMI)...
November 2017: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29275908/centralisation-for-resection-of-the-pancreatic-head-a-comparison-of-operative-factors-and-early-outcomes-during-the-evolving-unit-and-tertiary-unit-phases-at-a-uk-institution
#11
M Kostalas, H Nageswaran, S Froghi, A Riga, R Kumar, N Menezes, T R Worthington, N D Karanjia
AIMS: To assess impact of centralisation on patients undergoing pancreatic head resections at a tertiary hepatobiliary (HPB) centre in the UK. METHODS: Data were analysed from a prospectively maintained database from 1998 to 2014 on all patients undergoing pancreatic head resections. Two specific time periods were defined; these were the evolving unit phase (EU) from 1998 to 2009 and finally the established tertiary unit phase (TU) from 2010 to 2014. Peri-operative factors and post-operative outcomes were analysed...
August 19, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29221960/when-everything-else-fails-high-pressure-balloon-for-undilatable-lesions
#12
REVIEW
Ioannis Felekos, Grigoris V Karamasis, Antonis N Pavlidis
Heavily calcified lesions are encountered with increasing frequency during percutaneous coronary interventions (PCI). This poses a significant problem as it often leads to suboptimal stent expansion, which in turn is a major cause for stent restenosis and thrombosis. Various technologies have been developed to tackle this. The high-pressure balloon (OPN) seems to be a promising adjunct in treating undilatable lesions. In this concise mini review we highlight the use of HPB and we present the current status of technology implemented in complex PCI cases...
November 10, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29206676/hepatobiliary-hands-of-hopkins
#13
Henry A Pitt
OBJECTIVE: This historical perspective documents the role that John L. Cameron played in advancing hepatobiliary research, education, and surgery at Johns Hopkins in the 1970s, 1980s, and 1990s. SUMMARY OF BACKGROUND DATA: Dating back to William S. Halsted in the 19th century, leaders of the Department of Surgery at Johns Hopkins have been interested in hepatobiliary disease and surgery. John L. Cameron had broad hepato-pancreato-biliary (HPB) interests when he completed his surgical training...
December 4, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29203661/unusual-zinc-binding-mode-of-hdac6-selective-hydroxamate-inhibitors
#14
Nicholas J Porter, Adaickapillai Mahendran, Ronald Breslow, David W Christianson
Histone deacetylases (HDACs) regulate myriad cellular processes by catalyzing the hydrolysis of acetyl-l-lysine residues in histone and nonhistone proteins. The Zn2+-dependent class IIb enzyme HDAC6 regulates microtubule function by deacetylating α-tubulin, which suppresses microtubule dynamics and leads to cell cycle arrest and apoptosis. Accordingly, HDAC6 is a target for the development of selective inhibitors that might be useful in new therapeutic approaches for the treatment of cancer, neurodegenerative diseases, and other disorders...
December 4, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29199380/liver-resection-for-hcc-outside-the-bclc-criteria
#15
Manish S Bhandare, Shraddha Patkar, Nitin Shetty, Ashwin Polnaya, Suyash Kulkarni, Rohit R Dusane, Shailesh V Shrikhande, Mahesh Goel
PURPOSE: Surgical resection still remains the mainstay of management of hepatocellular carcinoma (HCC). At present, Barcelona clinic liver cancer (BCLC) staging is the most widely used tool to guide treatment; however, criteria for offering surgery as curative treatment are restrictive. We aimed to evaluate short-term and long-term outcomes of HCC after resection, even for patients outside BCLC criteria for resection. METHODS: Data was collected from a prospective database from GI and HPB Department, Tata Memorial Hospital, Mumbai...
December 4, 2017: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/29159756/patient-provider-communication-and-health-outcomes-among-individuals-with-hepato-pancreato-biliary-disease-in-the-usa
#16
Qinyu Chen, Eliza W Beal, Eric B Schneider, Victor Okunrintemi, Xu-Feng Zhang, Timothy M Pawlik
BACKGROUND: Patient-provider communication (PPC) is utilized as a value-based metric in pay-for-performance programs. We sought to evaluate the association of PPC with patient-reported health outcomes, as well as healthcare resource utilization among a nationally representative cohort of patients with hepato-pancreato-biliary (HPB) diagnoses. METHODS: Patients with HPB diseases were identified from the 2008-2014 Medical Expenditure Panel Survey cohort. A weighted PPC composite score was categorized using the responses from the CAHPS (Consumer Assessment of Healthcare Providers and Systems) survey as optimal, average, or poor...
November 20, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29135498/state-of-the-john-l-cameron-md-division-of-hepatobiliary-and-pancreatic-surgery-the-program-that-john-cameron-built
#17
Ammar A Javed, Christopher L Wolfgang
: The pancreatic surgery program at Johns Hopkins is recognized as being among the top programs in the field. It is part of the newly formed John L. Cameron Division of HPB surgery. This division of surgery is a highly productive group of academic surgeons in terms of clinical volume, research endeavors, and education. The division functions as part of a large multidisciplinary group at Johns Hopkins. The program has an interesting history and can trace its roots back to the actions of a single individual-John L...
November 13, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29132195/current-evidence-for-the-use-of-n-acetylcysteine-following-liver-resection
#18
REVIEW
Richard Kemp, Jonathan Mole, Dhanny Gomez
BACKGROUND: N-acetylcysteine (NAC) has many uses in medicine; notable in the management of paracetamol toxicity, acute liver failure and liver surgery. The aim of this review was to critically appraise the published literature for the routine use of NAC in liver resection surgery. METHODS: An electronic search was performed of EBSCOhost (Medline and CINAHL database), PubMed and the Cochrane Library for the period 1990-2016. MeSH headings: 'acetyl-cysteine', 'liver resection' and 'hepatectomy' were used to identify all relevant articles published in English...
November 13, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29110059/differentiating-focal-nodular-hyperplasia-from-hepatocellular-adenoma-is-hepatobiliary-phase-mri-hbp-mri-using-linear-gadolinium-chelates-always-useful
#19
Marion Roux, Frederic Pigneur, Laurence Baranes, Julien Calderaro, Mélanie Chiaradia, Thomas Decaens, Sandrine Kastahian, Anaïs Charles-Nelson, Lambros Tselikas, Charlotte Costentin, Alexis Laurent, Daniel Azoulay, Ariane Mallat, Alain Rahmouni, Alain Luciani
PURPOSE: To assess the value of Hepatobiliary phase MRI (HPB-MRI) to differentiate FNH and HCA, and evaluate its impact on diagnostic accuracy, diagnostic confidence, inter-observer variability, and patient clinical management. METHODS: Forty-nine patients referred for Gd-BOPTA-enhanced MRI were retrospectively included in this IRB-approved study, with a total of 119 lesions-90 FNH and 29 HCA. Two observers separately assessed in 2 distinct randomized reading sessions the performance of MRI with (HBP-MRI) or without (conventional MRI) the use of HBP images...
November 6, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29101562/academic-status-does-not-affect-outcome-following-complex-hepato-pancreato-biliary-procedures
#20
Maria S Altieri, Jie Yang, Donald Groves, Donglei Yin, Kristen Cagino, Mark Talamini, Aurora Pryor
INTRODUCTION: There is a growing debate regarding outcomes following complex hepato-pancreato-biliary (HPB) procedures. The purpose of our study is to examine if facility type has any impact on complications, readmission rates, emergency department (ED) visit rates, and length of stay (LOS) for patients undergoing HPB surgery. METHODS: The SPARCS administrative database was used to identify patients undergoing complex HPB procedures between 2012 and 2014 in New York...
November 3, 2017: Surgical Endoscopy
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