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https://www.readbyqxmd.com/read/28647840/interaction-of-ferulic-acid-with-glutathione-s-transferase-and-carboxylesterase-genes-in-the-brown-planthopper-nilaparvata-lugens
#1
Jun Yang, Xiao-Qin Sun, Shu-Ying Yan, Wen-Jun Pan, Mao-Xin Zhang, Qing-Nian Cai
Plant phenolics are crucial defense phytochemicals against herbivores and glutathione S-transferase (GST) and carboxylesterase (CarE) in herbivorous insects are well-known detoxification enzymes for such xenobiotics. To understand relationship between a plant phenolic and herbivore GST or CarE genes, we evaluated the relationship between a rice phenolic ferulic acid and resistance to brown planthopper (BPH, Nilaparvata lugens), and investigated the interaction of ferulic acid with GST or CarE genes in BPH. The results indicate that ferulic acid content in tested rice varieties was highly associated with resistance to BPH...
June 24, 2017: Journal of Chemical Ecology
https://www.readbyqxmd.com/read/28646227/size-dependent-uptake-and-hemolytic-effect-of-zinc-oxide-nanoparticles-on-erythrocytes-and-biomedical-potential-of-zno-ferulic-acid-conjugates
#2
E Preedia Babu, A Subastri, A Suyavaran, K Premkumar, V Sujatha, B Aristatile, Ghedeir M Alshammari, V Dharuman, C Thirunavukkarasu
Despite zinc oxide nanoparticles (ZnONPs) being increasingly used as carriers in biomedical fields due to their multifaceted properties and therapeutic importance, better understanding of the mechanisms and cellular consequences resulting from their interaction with cells and cellular components has been warranted. In the present study, we investigate the size-dependent interaction of ZnONPs on RBCs, and its impact on cell viability, DNA damage, ROS generation and morphological changes, employing cellular and analytical methods...
June 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28642684/ferulic-acid-improves-functional-recovery-after-acute-spinal-cord-injury-in-rats-by-inducing-hypoxia-to-inhibit-microrna-590-and-elevate-vascular-endothelial-growth-factor-expressions
#3
Zhenjie Li, Shengyun Wang, Wenfang Li, Hongbin Yuan
Spinal cord injury (SCI) is the leading cause of paralysis, disability and even death in severe cases, and neural stem cells (NSCs) transplant has been employed for repairing SCI. Ferulic acid (FA) is able to promote neurogenesis in various stem cell therapies. We aimed to investigate the effect of FA on NSC transplant therapy, and the underlying mechanism, in improving functional recovery in SCI rat model. A rat model of SCI was established, which then received transplant of NSCs with or without FA pre-treatment...
2017: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/28641405/biotransformation-of-ferulic-acid-to-protocatechuic-acid-by-corynebacterium-glutamicum-atcc-21420-engineered-to-express-vanillate-o-demethylase
#4
Naoko Okai, Takaya Masuda, Yasunobu Takeshima, Kosei Tanaka, Ken-Ichi Yoshida, Masanori Miyamoto, Chiaki Ogino, Akihiko Kondo
Ferulic acid (4-hydroxy-3-methoxycinnamic acid, FA) is a lignin-derived phenolic compound abundant in plant biomass. The utilization of FA and its conversion to valuable compounds is desired. Protocatechuic acid (3,4-dihydroxybenzoic acid, PCA) is a precursor of polymers and plastics and a constituent of food. A microbial conversion system to produce PCA from FA was developed in this study using a PCA-producing strain of Corynebacterium glutamicum F (ATCC 21420). C. glutamicum strain F grown at 30 °C for 48 h utilized 2 mM each of FA and vanillic acid (4-hydroxy-3-methoxybenzoic acid, VA) to produce PCA, which was secreted into the medium...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28640960/ferulic-acid-alleviates-symptoms-of-preeclampsia-in-rats-by-upregulating-vascular-endothelial-growth-factor
#5
Weiyan Gong, Jipeng Wan, Qing Yuan, Quanzhan Man, Xiaojing Zhang
Preeclampsia is a complication affecting pregnant women worldwide, which leads to maternal and fetal morbidity and mortality. In this study, we evaluated the efficacy of ferulic acid (FA) on an N(ω) -nitro-L-arginine methyl ester hydrochloride (L-NAME) induced rat model of preeclampsia. L-NAME was administered to pregnant rats to induce preeclampsia. 48 rats were divided into three experimental groups (n=16 each): control group, preeclampsia group and preeclampsia with FA treatment (preeclampsia+FA). Physiological characteristics such as urine volume, total urine protein and blood pressure were assessed...
June 22, 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/28640190/trans-cinnamic-and-chlorogenic-acids-affect-the-secondary-metabolic-profiles-and-ergosterol-biosynthesis-by-fusarium-culmorum-and-f-graminearum-sensu-stricto
#6
Tomasz Kulik, Kinga Stuper-Szablewska, Katarzyna Bilska, Maciej Buśko, Anna Ostrowska-Kołodziejczak, Dariusz Załuski, Juliusz Perkowski
Plant-derived compounds limiting mycotoxin contamination are currently of major interest in food and feed production. However, their potential application requires an evaluation of their effects on fungal secondary metabolism and membrane effects. In this study, different strains of Fusarium culmorum and F. graminearum sensu stricto were exposed to trans-cinnamic and chlorogenic acids on solid YES media. Fusaria produced phenolic acids, whose accumulation was lowered by exogenous phenolic compounds. In addition, fungi reduced exogenous phenolic acids, leading either to their conversion or degradation...
June 22, 2017: Toxins
https://www.readbyqxmd.com/read/28634228/spatial-mapping-and-profiling-of-metabolite-distributions-during-germination
#7
Adam D Feenstra, Liza E Alexander, Zhihong Song, Andrew R Korte, Marna Yandeau-Nelson, Basil J Nikolau, Young-Jin Lee
Germination is a highly complex process by which seeds begin to develop and establish themselves as viable organisms. In this paper, we utilize a combination of GC-MS, LC-fluorescence, and mass spectrometry imaging (MSI) approaches to profile and visualize the metabolic distributions of germinating seeds from two different inbreds of maize seeds, B73 and Mo17. GC and LC analyses demonstrate that the two inbreds are highly differentiated in their metabolite profiles throughout the course of germination, especially with regard to amino acids, sugar alcohols, and small organic acids...
June 20, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28631780/tuning-the-photocatalytic-activity-of-bismuth-wolframate-towards-selective-oxidations-for-the-biorefinery-driven-by-solar-light
#8
Rosaria Ciriminna, Riccardo Delisi, Francesco Parrino, Leonardo Palmisano, Mario Pagliaro
The sol-gel entrapment of nanostructured Bi2WO6 enhances the activity and the selectivity of the short-gap semiconductor in the sunlight-driven photo-oxidation of trans-ferulic and trans-cinnamic acid dissolved in water with air as the primary oxidant. Valuable products such as vanillin, benzaldehyde, benzoic acid and vanillic acid are obtained. This provides the proof of concept that photocatalysis could be a promising technology in tomorrow's solar biorefineries.
June 20, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28629185/leptadenia-reticulata-retz-wight-arn-jivanti-botanical-agronomical-phytochemical-pharmacological-and-biotechnological-aspects
#9
REVIEW
Sudipta Kumar Mohanty, Mallappa Kumara Swamy, Uma Rani Sinniah, Maniyam Anuradha
Leptadenia reticulata (Retz.) Wight & Arn. (Apocynaceae), is a traditional medicinal plant species widely used to treat various ailments such as tuberculosis, hematopoiesis, emaciation, cough, dyspnea, fever, burning sensation, night blindness, cancer, and dysentery. In Ayurveda, it is known for its revitalizing, rejuvenating, and lactogenic properties. This plant is one of the major ingredients in many commercial herbal formulations, including Speman, Envirocare, Calshakti, Antisept, and Chyawanprash. The therapeutic potential of this herb is because of the presence of diverse bioactive compounds such as α-amyrin, β-amyrin, ferulic acid, luteolin, diosmetin, rutin, β-sitosterol, stigmasterol, hentricontanol, a triterpene alcohol simiarenol, apigenin, reticulin, deniculatin, and leptaculatin...
June 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28628837/the-influence-of-essential-oils-from-xiang-fu-si-wu-decoction-on-its-non-volatile-components-and-its-application-for-pharmacokinetics-in-normal-rats
#10
Ying Pan, Dawei Qian, Pei Liu, Yang Zhang, Zhenhua Zhu, Li Zhang, Jin-Ao Duan
Xiang-Fu-Si-Wu Decoction (XFSWD) has been used to treat gynecology diseases in clinical practice for hundreds of years in China, especially for primary dysmenorrheal of QiZhi Type. In previous researches, both essential oils (XEO) and non-volatile components (NXEO) extracted from XFSWD showed significant pharmacological activities, but the influence of XEO on NXEO was unclear. The purpose of this paper was to develop a validated analytical method for simultaneous determination of ten components including Vanillic acid, Ferulic acid, Caffeic acid, Gallic acid, Paeoniflorin, Albiflorin, Tetrahydropalmatine, Protopine, Berberine and Tetrahydrocolumbamine, and to compare the pharmacokinetic parameters of these components to illustrate the influences of XEO on NXEO in normal rats...
June 4, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28627304/the-effects-of-selected-phytochemicals-on-biofilm-formed-by-five-methicillin-resistant-staphylococcus-aureus
#11
Barbara Kot, Kamila Wierzchowska, Agata Grużewska, Dzmitry Lohinau
The aim of this study was to evaluate the ability of 0.1% thyme oil (TO), trans-cinnamaldehyde (TC), ferulic acid (FA), p-coumaric acid (p-CA), caffeic acid (CA), lavender essential oil (LO), geranium essential oil (GO) and tee tree oil (TTO) to control biofilms formed by methicillin-resistant Staphylococcus aureus (MRSA) strains. Depending on the strains, TO reduced 59.7-85% of biofilm mass, while TC 52.9-82.4% after 48 h of treatment. Reduction of metabolic activity of biofilms in ranges 79.3-86% and 85...
June 18, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28626590/antiglycemic-effect-of-water-extractable-arabinoxylan-from-wheat-aleurone-and-bran
#12
Lovemore Nkhata Malunga, Marta Izydorczyk, Trust Beta
The studies on the effects of arabinoxylan (AX) polysaccharides on postprandial glucose response have resulted in contrasting results owing to the diversity in AX structures. Four water extractable AX (WEAX) extracts obtained from wheat aleurone and bran were used to investigate (a) the effect of AX on activities of α-amylase and α-glucosidase, (b) influence of AX chemical composition on their inhibition potency, and (c) kinetics of enzyme inhibition. α-Amylase activity was not significantly affected by the presence WEAX fractions regardless of type or concentration...
2017: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28626449/characterization-of-feruloyl-esterases-produced-by-the-four-lactobacillus-species-l-amylovorus-l-acidophilus-l-farciminis-and-l-fermentum-isolated-from-ensiled-corn-stover
#13
Zhenshang Xu, Huiying He, Susu Zhang, Tingting Guo, Jian Kong
Lactic acid bacteria (LAB) play important roles in silage fermentation, which depends on the production of sufficient organic acids to inhibit the growth of undesirable microorganisms. However, LAB are not able to degrade cellulose and hemicellulose. Bacteria and fibrolytic enzymes are usually used as inoculants to improve the silage quality and digestibility. In the present study, we isolated four Lactobacillus strains (L. amylovorus CGMCC 11056, L. acidophilus CCTCC AB2010208, L. farciminis CCTCC AB2016237 and L...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28617955/expression-atlas-and-comparative-coexpression-network-analyses-reveal-important-genes-involved-in-the-formation-of-lignified-cell-wall-in-brachypodium-distachyon
#14
Richard Sibout, Sebastian Proost, Bjoern Oest Hansen, Neha Vaid, Federico M Giorgi, Severine Ho-Yue-Kuang, Frédéric Legée, Laurent Cézart, Oumaya Bouchabké-Coussa, Camille Soulhat, Nicholas Provart, Asher Pasha, Philippe Le Bris, David Roujol, Herman Hofte, Elisabeth Jamet, Catherine Lapierre, Staffan Persson, Marek Mutwil
While Brachypodium distachyon (Brachypodium) is an emerging model for grasses, no expression atlas or gene coexpression network is available. Such tools are of high importance to provide insights into the function of Brachypodium genes. We present a detailed Brachypodium expression atlas, capturing gene expression in its major organs at different developmental stages. The data were integrated into a large-scale coexpression database ( www.gene2function.de), enabling identification of duplicated pathways and conserved processes across 10 plant species, thus allowing genome-wide inference of gene function...
June 15, 2017: New Phytologist
https://www.readbyqxmd.com/read/28610437/a-new-ferulic-acid-ester-from-rhodiola-wallichiana-var-cholaensis-crassulaceae
#15
Yaling Song, Jianming Zhou, Xuejing Wang, Xue Xie, Yiwu Zhao, Fuyong Ni, Wenzhe Huang, Zhenzhong Wang, Wei Xiao
A new ferulic acid ester, 6-feruloyloxyhexanoic acid (1), was isolated along with 10 known ones (2-11), from the concentrated water extract of Rhodiola wallichiana var. cholaensis. Their chemical structures were elucidated on the basis of extensive spectroscopic methods including Two-dimensional nuclear magnetic resonance (2D NMR) experiments. Compound 3 was isolated from this plant for the first time. The protective effects against H2O2-induced myocardial cell injury in cultured H9c2 cells were also evaluated...
June 14, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28608752/ferulic-acid-and-its-water-soluble-derivatives-inhibit-nitric-oxide-production-and-inducible-nitric-oxide-synthase-expression-in-rat-primary-astrocytes
#16
Masaki Kikugawa, Tomoaki Ida, Hideshi Ihara, Tatsuji Sakamoto
We recently reported that two water-soluble derivatives of ferulic acid (1-feruloyl glycerol, 1-feruloyl diglycerol) previously developed by our group exhibited protective effects against amyloid-β-induced neurodegeneration in vitro and in vivo. In the current study, we aimed to further understand this process by examining the derivatives' ability to suppress abnormal activation of astrocytes, the key event of neurodegeneration. We investigated the effects of ferulic acid (FA) derivatives on nitric oxide (NO) production and inducible nitric oxide synthase (iNOS) expression in rat primary astrocytes...
June 13, 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/28608557/salicornia-extract-ameliorates-salt-induced-aggravation-of-nonalcoholic-fatty-liver-disease-in-obese-mice-fed-a-high-fat-diet
#17
Jae Hwan Kim, Sujin Suk, Woo Jung Jang, Chang Hyung Lee, Jong-Eun Kim, Jin-Kyu Park, Mee-Hyang Kweon, Jong Hun Kim, Ki Won Lee
High-fat and high-salt intakes are among the major risks of chronic diseases including obesity, nonalcoholic fatty liver disease (NAFLD), and nonalcoholic steatohepatitis (NASH). Salicornia is a halophytic plant known to exert antioxidant, antidiabetic, and hypolipidemic effects, and Salicornia-extracted salt (SS) has been used as a salt substitute. In this study, the effects of SS and purified salt (PS) on the aggravation of NAFLD/NASH were compared. C57BL/6J male mice (8-wk-old) were fed a high-fat diet (HFD) for 6 mo and divided into 3 dietary groups, which were additionally fed HFD, HFD + SS, and HFD + PS for 13 wk...
June 13, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28608235/ferulic-acid-supplementation-for-management-of-depression-in-epilepsy
#18
Tanveer Singh, Taranjot Kaur, Rajesh Kumar Goel
Neuroinflammation driven altered neurochemical milieu have been reported to play a significant role in pathogenesis of comorbid depression in epilepsy. Most of the antiepileptic drugs (AEDs) such as levetiracetam, taigabine, topiramate have not been reported any significant effect in alleviating neuroinflammation, which may explain their ineffectiveness in ameliorating depression associated with epilepsy. The supplementation of antidepressants (ADs) attracts various pharmacokinetic and pharmacodynamic interactions with AEDs and was considered unsafe in epilepsy...
June 12, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28600204/antioxidant-antimicrobial-cell-viability-and-enzymatic-inhibitory-of-antioxidant-polymers-as-biological-macromolecules
#19
REVIEW
Hadi Hashemi Gahruie, Mehrdad Niakousari
Polymeric antioxidants such as Catechinaldehyde Polycondensates, Catechin-acelaldehydepolycondensates, Flavonoid-grafted chitosan fibers, Ferulate hydrogel, Dextran ferulate hydrogel, Starch-quercetin conjugate, Gallic acid- and Caffeic acid-functionalized chitosan, Gallic acid - chitosan conjugate, Poly(rutin), Gallic acid grafted chitosan, Dextran-Catechin Conjugate belong to biological macromolecules. These kinds of compounds have stronger antioxidant potential and pharmacokinetic activities, as compared to similar low molecular weight preservatives...
June 6, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28598504/microencapsulation-of-corn-wastewater-nejayote-phytochemicals-by-spray-drying-and-their-release-under-simulated-gastrointestinal-digestion
#20
Javier Villela-Castrejón, Beatriz A Acosta-Estrada, Janet A Gutiérrez-Uribe
Corn lime cooking generates a large amount of wastewater known as nejayote that is composed of suspended solids and solubilized phytochemicals. Spray drying can be an alternative to recover bioactive molecules, such as ferulic acid, from nejayote. Besides the yield, the physicochemical properties (solubility, water activity, pH, moisture, hygroscopicity, total phenolic content, and distribution of free and bound hydroxycinnamic acids) of spray-dried nejayote powders were analyzed. The powders were obtained at 200 °C/100 °C or 150 °C/75 °C (inlet/outlet) air temperatures with the addition of maltodextrin (MD) or 2-hydroxypropyl-beta-cyclodextrin (HBCD) as encapsulating agents...
June 9, 2017: Journal of Food Science
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