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https://www.readbyqxmd.com/read/29774071/molecular-detection-and-analysis-of-exosomes-using-surface-enhanced-raman-scattering-gold-nanorods-and-a-miniaturized-device
#1
Elyahb Allie Kwizera, Ryan O'Connor, Vojtech Vinduska, Melody Williams, Elizabeth R Butch, Scott E Snyder, Xiang Chen, Xiaohua Huang
Exosomes are a potential source of cancer biomarkers. Probing tumor-derived exosomes can offer a potential non-invasive way to diagnose cancer, assess cancer progression, and monitor treatment responses. Novel molecular methods would facilitate exosome analysis and accelerate basic and clinical exosome research. Methods: A standard gold-coated glass microscopy slide was used to develop a miniaturized affinity-based device to capture exosomes in a target-specific manner with the assistance of low-cost 3-D printing technology...
2018: Theranostics
https://www.readbyqxmd.com/read/29770491/customised-spectacles-using-3-d-printing-technology
#2
Onder Ayyildiz
BACKGROUND: This study describes a novel method of customised spectacles prototyping and manufacturing using 3-D printing technology. METHODS: The procedure for manufacturing customised spectacles using 3-D printing technology in this study involved five steps: patient selection; using surface topography; 3-D printing of the phantom model; 3-D designing of the spectacles; and 3-D printing of the spectacles. RESULTS: The effective time required for 3-D printing of the spectacles was 14 hours...
May 16, 2018: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29768120/three-dimensionally-printed-pearl-powder-poly-caprolactone-composite-scaffolds-for-bone-regeneration
#3
Xu Zhang, Xiaoyu Du, Dejian Li, Rongguang Ao, Bin Yu, Baoqing Yu
Pearl has great potential as a natural biomaterial for bone tissue engineering, but it suffers from low porosity, difficulty in molding, and poor anti-buckling property. In this study, we used the 3-D printing technique to fabricate original pearl powder and PCL composite scaffolds with different concentrations of pearl powder. The four groups of scaffolds were termed PCL, 30% Pearl/PCL, 50% Pearl/PCL and 80% Pearl/PCL scaffolds according to the proportion of pearl powder. The samples were systematically investigated by scanning electron microscopy (SEM), wide-angle XRD, liquid substitution, Zwick static materials testing, and energy dispersive X-ray analysis...
May 16, 2018: Journal of Biomaterials Science. Polymer Edition
https://www.readbyqxmd.com/read/29757158/origins-of-the-changing-detector-response-in-small-megavoltage-photon-radiation-fields
#4
John D Fenwick, Georgios Georgiou, Carl Graham Rowbottom, Tracy S A Underwood, Sudhir Kumar, Alan E Nahum
Differences in detector response between measured small fields, fclin, and wider reference fields, fmsr, can be overcome by using correction factors or by designing detectors with field-size invariant responses. The changing response in small fields is caused by perturbations of the electron fluence within the detector sensitive volume. For solid-state detectors, it has recently been suggested that these perturbations might be caused by the non-water-equivalent effective atomic numbers Z of detector materials, rather than by their non-water-like densities...
May 14, 2018: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29750892/erratum
#5
(no author information available yet)
Chen LW, Gregg A, Palm D. Longitudinal evaluation of quality improvement and public health accreditation readiness in Nebraska local health departments, 2011-2016. Public Health Rep. 2018;133(3):250-256. (Original DOI: 10.1177/0033354918754542) There was an error with respect to Figures 2 and 3 in the original published version of this article. The article has been corrected online and in print.
January 1, 2018: Public Health Reports
https://www.readbyqxmd.com/read/29750754/the-barrow-biomimetic-spine-fluoroscopic-analysis-of-a-synthetic-spine-model-made-of-variable-3d-printed-materials-and-print-parameters
#6
Michael A Bohl, Michael A Mooney, Garrett J Repp, Peter Nakaji, Steve W Chang, Jay D Turner, U Kumar Kakarla
STUDY DESIGN: Objective and subjective fluoroscopic assessments of a new synthetic spine model. OBJECTIVE: To analyze the fluoroscopic performance and fidelity to human tissue of a new synthetic spine model. SUMMARY OF BACKGROUND DATA: The [blinded for review] Biomimetic Spine project aims to develop a 3-dimensional (3D) printed, synthetic spine model that will one day replace cadaveric tissue in spine biomechanical research. A crucial component to any biomimetic spine model is that it performs similarly to cadaveric tissue on standard diagnostic imaging modalities...
May 10, 2018: Spine
https://www.readbyqxmd.com/read/29733278/design-and-characterization-of-an-acoustically-and-structurally-matched-3-d-printed-model-for-transcranial-ultrasound-imaging
#7
Chen Bai, Meiling Ji, Ayache Bouakaz, Yujin Zong, Mingxi Wan
For investigating human transcranial ultrasound imaging (TUI) through the temporal bone, an intact human skull is needed. Since it is complex and expensive to obtain one, it requires that experiments are performed without excision or abrasion of the skull. Besides, to mimic blood circulation for the vessel target, cellulose tubes generally fit the vessel simulation with straight linear features. These issues, which limit experimental studies, can be overcome by designing a 3-D-printed skull model with acoustic and dimensional properties that match a real skull and a vessel model with curve and bifurcation...
May 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29730456/outcome-and-safety-analysis-of-3d-printed-patient-specific-pedicle-screw-jigs-for-complex-spinal-deformities-a-comparative-study
#8
Bhavuk Garg, Manish Gupta, Menaka Singh, Dinesh Kalyanasundaram
BACKGROUND CONTEXT: Spinal deformities are very challenging to treat and have a great risk of neurological complications due to hardware placement during corrective surgery. Various techniques have been introduced to ensure safe and accurate placement of pedicle screws. Patient-specific screw guides with pre-drawn and pre-validated trajectory seems to be an attractive option. PURPOSE: We have focused on developing 3D printing technique for complex spinal deformities in India...
May 3, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29725268/mesoporous-bioactive-glass-coated-3d-printed-borosilicate-bioactive-glass-scaffolds-for-improving-repair-of-bone-defects
#9
Xin Qi, Hui Wang, Yadong Zhang, Libin Pang, Wei Xiao, Weitao Jia, Shichang Zhao, Deping Wang, Wenhai Huang, Qiugen Wang
Background: In the field of tissue engineering, there is currently increasing interest in new biomedical materials with high osteogenic ability and comparable mechanical function to repair bone defects. Three-dimensional (3-D) bioactive borosilicate glass (BG) scaffolds exhibit uniform interconnected macro-pores, high porosity and high compressive strength. In this study, we fabricated 3-D BG scaffolds by the 3D printing technique, then coated the surface of the 3-D BG scaffolds with mesoporous bioactive glass (MBG) (BG-MBG scaffold)...
2018: International Journal of Biological Sciences
https://www.readbyqxmd.com/read/29710318/a-3-dimensional-printed-short-segment-template-prototype-for-mandibular-fracture-repair
#10
Parul Sinha, Gary Skolnick, Kamlesh B Patel, Gregory H Branham, John J Chi
Importance: After reduction of complex mandibular fractures, contouring of the fracture plates to fixate the reduced mandibular segments can be time-consuming. Objective: To explore the potential application of a 3-dimensional (3-D)-printed short-segment mandibular template in the management of complex mandibular fractures. Design, Setting, and Participants: A feasibility study was performed at a tertiary academic center using maxillofacial computed tomography data of 3 patients with comminuted mandibular fractures who required preoperative planning with a perfected complete mandible model...
April 26, 2018: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/29707454/virtual-incision-pattern-planning-using-three-dimensional-images-for-optimization-of-syndactyly-surgery
#11
Inge A Hoevenaren, Rinaldo D Vreeken, Arico C Verhulst, Dietmar J O Ulrich, Thomas J J Maal, Till Wagner
Syndactyly is a congenital condition characterized by fusion of the fingers. If not treated correctly during infancy, syndactyly may hinder the normal development of hand function. Many surgical techniques have been developed, with the main goal to create a functional hand with the smallest number of operative corrections. Therefore, exact preoperative planning of the reconstructive procedure is essential. An imaging method commonly used for preoperative planning is 3-dimensional (3D) surface imaging. The goal of this study was to implement the use of this technique in hand surgery, by designing a virtual planning tool for a desyndactylization procedure based on 3D hand images...
March 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29699451/an-explore-transplant-group-randomized-controlled-education-trial-to-increase-dialysis-patients-decision-making-and-pursuit-of-transplantation
#12
Amy D Waterman, John Devin Peipert
INTRODUCTION: Dialysis centers must provide transplant education to patients but often do not address the risks and benefits of living and deceased donor transplant. RESEARCH QUESTIONS: In a group randomized controlled trial of 20 dialysis centers and 253 patients, we assessed whether the Explore Transplant education program increased patients' readiness to pursue transplant, transplant knowledge, informed transplant decision-making, discussions about transplant with potential living donors, pursuit and receipt of living or deceased donor transplant, and whether these effects varied by race...
January 1, 2018: Progress in Transplantation
https://www.readbyqxmd.com/read/29667682/modeling-the-free-radical-polymerization-of-hexanediol-diacrylate-hdda-a-molecular-dynamics-and-graph-theory-approach
#13
Ariana Torres-Knoop, Ivan Kryven, Verena Schamboeck, Piet D Iedema
In the printing, coating and ink industries, photocurable systems are becoming increasingly popular and multi-functional acrylates are one of the most commonly used monomers due to their high reactivity (fast curing). In this paper, we use molecular dynamics and graph theory tools to investigate the thermo-mechanical properties and topology of hexanediol diacrylate (HDDA) polymer networks. The gel point was determined as the point where a giant component was formed. For the conditions of our simulations, we found the gel point to be around 0...
April 18, 2018: Soft Matter
https://www.readbyqxmd.com/read/29667396/direct-printing-of-graphene-electrodes-for-high-performance-organic-inverters
#14
Aditi Naik, Jae Joon Kim, Özlem Usluer, D Leonardo Gonzalez Arellano, Ethan B Secor, Antonio Facchetti, Mark C Hersam, Alejandro L Briseno, James J Watkins
The scalable fabrication of high-resolution electrodes and interconnects is necessary to enable advanced, high-performance, printed and flexible electronics. Here, we demonstrate the direct printing of graphene patterns with feature widths from 300 µm to ~310 nm by liquid-bridge-mediated nanotransfer molding. This solution-based technique enables residue-free printing of graphene patterns on a variety of substrates with surface energies between ~43 and 73 mN m-1 . Using printed graphene source and drain electrodes, high-performance organic field-effect transistors (OFETs) are fabricated with single-crystal rubrene (p-type) and fluorocarbon-substituted dicyanoperylene-3,4:9,10-bis(dicarboximide) (PDIF-CN2 ) (n-type) semiconductors...
April 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29667223/mental-health-and-well-being-in-parents-of-excessively-crying-infants-prospective-evaluation-of-a-support-package
#15
C Powell, D Bamber, J Long, R Garratt, J Brown, S Rudge, T Morris, N Bhupendra Jaicim, R Plachcinski, S Dyson, E M Boyle, I St James-Roberts
BACKGROUND: During the first 4 months of age, approximately 20% of infants cry a lot without an apparent reason. Most research has targeted the crying, but the impact of the crying on parents, and subsequent outcomes, need to receive equal attention. This study reports the findings from a prospective evaluation of a package of materials designed to support the well-being and mental health of parents who judge their infant to be crying excessively. The resulting "Surviving Crying" package comprised a website, printed materials, and programme of Cognitive Behaviour Therapy-based support sessions delivered to parents by a qualified practitioner...
April 17, 2018: Child: Care, Health and Development
https://www.readbyqxmd.com/read/29660055/accuracy-assessment-of-pedicle-and-lateral-mass-screw-insertion-assisted-by-customized-3d-printed-drill-guides-a-human-cadaver-study
#16
Peter A J Pijpker, Joep Kraeima, Max J H Witjes, D L Marinus Oterdoom, Maarten H Coppes, Rob J M Groen, Jos M A Kuijlen
BACKGROUND: Accurate cervical screw insertion is of paramount importance considering the risk of damage to adjacent vital structures. Recent research in 3-dimensional (3D) technology describes the advantage of patient-specific drill guides for accurate screw positioning, but consensus about the optimal guide design and the accuracy is lacking. OBJECTIVE: To find the optimal design and to evaluate the accuracy of individualized 3D-printed drill guides for lateral mass and pedicle screw placement in the cervical and upper thoracic spine...
April 5, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29659609/patients-perceived-needs-of-osteoarthritis-health-information-a-systematic-scoping-review
#17
Louisa Chou, Lisa Ellis, Michelle Papandony, K L Maheeka D Seneviwickrama, Flavia M Cicuttini, Kaye Sullivan, Andrew J Teichtahl, Yuanyuan Wang, Andrew M Briggs, Anita E Wluka
BACKGROUND: Optimal management of osteoarthritis requires active patient participation. Understanding patients' perceived health information needs is important in order to optimize health service delivery and health outcomes in osteoarthritis. We aimed to review the existing literature regarding patients' perceived health information needs for OA. METHODS: A systematic scoping review was performed of publications in MEDLINE, EMBASE, CINAHL and PsycINFO (1990-2016)...
2018: PloS One
https://www.readbyqxmd.com/read/29658034/generation-of-3-dimensional-multi-patches-on-silica-particles-via-printing-with-wrinkled-stamps
#18
D John, M Zimmermann, A Böker
A simple route towards patchy particles with anisotropic patches with respect to a different functionality and directionality is presented. This method is based on microcontact printing of positively charged polyethylenimine (PEI) on silica particles using wrinkled stamps. Due to the wrinkled surface, the number of patches on the particles as well as the distance between two patches can be controlled.
April 16, 2018: Soft Matter
https://www.readbyqxmd.com/read/29621883/sentinel-wraps-real-time-monitoring-of-food-contamination-by-printing-dnazyme-probes-on-food-packaging
#19
Hanie Yousefi, M Monsur Ali, Hsuan-Ming Su, Carlos D M Filipe, Tohid F Didar
Here, we report the development of a transparent, durable, and flexible sensing surface that generates a fluorescence signal in the presence of a specific target bacterium. This material can be used in packaging, and it is capable of monitoring microbial contamination in various types of food products in real time without having to remove the sample or the sensor from the package. The sensor was fabricated by covalently attaching picoliter-sized microarrays of an E. coli-specific RNA-cleaving fluorogenic DNAzyme probe (RFD-EC1) to a thin, flexible, and transparent cyclo-olefin polymer (COP) film...
April 6, 2018: ACS Nano
https://www.readbyqxmd.com/read/29610093/cryo-ultrasonic-nde-ice-cold-ultrasonic-waves-for-the-detection-of-damage-in-complex-shaped-engineering-components
#20
Francesco Simonetti, Isaak L Satow, Alex J Brath, Kaden C Wells, John Porter, Brian Hayes, Kenneth Davis
Recent advances in computational methods, materials science, and new manufacturing processes are resulting in an unprecedented design flexibility which is driving the geometrical complexity of the components found in modern structures and machines. For safety-critical components, the geometrical complexity poses a significant challenge to the sensitivity of the existing nondestructive evaluation (NDE) methods available for the detection of manufacturing defects or damage that develops while a component is in service...
April 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
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