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3 d printing

Terrence R Tiersch, William T Monroe
Development of devices through design, prototyping, testing, and fabrication is especially necessary for enhancement of research and eventual application in cryobiology. The advent of 3-dimensional printing offers unique opportunities for this process, given that the materials involved are suitable for use in cryogenic temperatures. We report herein that 3-D printing with polylactic acid (PLA) thermoplastic is ideally suited for cryobiology device development. Devices that are designed and standardized in open-source fashion can be electronically distributed and created locally on increasingly affordable 3-D printers, and can accelerate cryobiology findings and improve reproducibility of results...
October 18, 2016: Cryobiology
Giovanni Fusco, Francesca Gallo, Cristina Tortolini, Paolo Bollella, Federica Ietto, Antonella De Mico, Andrea D'Annibale, Riccarda Antiochia, Gabriele Favero, Franco Mazzei
In this work, we developed an impedimetric label-free immunosensor for the detection of 2,4-Dichlorophenoxy Acetic Acid (2,4-D) herbicide either in standard solution and spiked real samples. For this purpose, we prepared by electropolymerization a conductive polymer poly-(aniline-co-3-aminobenzoic acid) (PANABA) then we immobilized anti-2,4-D antibody onto a nanocomposite AuNPs-PANABA-MWCNTs employing the carboxylic moieties as anchor sites. The nanocomposite was synthesized by electrochemical polymerization of aniline and 3-aminobenzoic acid, in the presence of a dispersion of gold nanoparticles, onto a multi-walled carbon nanotubes-based screen printed electrode...
October 5, 2016: Biosensors & Bioelectronics
Florian Tobias Alwin Kretz, Rahmin Khoramnia, Mary Safwat Attia, Michael Janusz Koss, Katharina Linz, Gerd Uwe Auffarth
PURPOSE: To evaluate postoperative outcomes and visual performance in intermediate distance after implantation of a +1.5 diopters (D) addition, aspheric, rotational asymmetric multifocal intraocular lens (MIOL). METHODS: Patients underwent bilateral cataract surgery with implantation of an aspheric, asymmetric MIOL with +1.5 D near addition. A complete ophthalmological examination was performed preoperatively and 3 months postoperatively. The main outcome measures were monocular and binocular uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UIVA), distance corrected intermediate visual acuity (DCIVA), uncorrected near visual acuity (UNVA) and distance corrected keratometry, and manifest refraction...
October 2016: Korean Journal of Ophthalmology: KJO
Samuel R Barber, Elliott D Kozin, Matthew Dedmon, Brian M Lin, Kyuwon Lee, Sumi Sinha, Nicole Black, Aaron K Remenschneider, Daniel J Lee
INTRODUCTION: Surgical simulators are designed to improve operative skills and patient safety. Transcanal Endoscopic Ear Surgery (TEES) is a relatively new surgical approach with a slow learning curve due to one-handed dissection. A reusable and customizable 3-dimensional (3D)-printed endoscopic ear surgery simulator may facilitate the development of surgical skills with high fidelity and low cost. Herein, we aim to design, fabricate, and test a low-cost and reusable 3D-printed TEES simulator...
November 2016: International Journal of Pediatric Otorhinolaryngology
Thorsten Jentzsch, Lazaros Vlachopoulos, Philipp Fürnstahl, Daniel A Müller, Bruno Fuchs
BACKGROUND: Sarcomas are associated with a relatively high local recurrence rate of around 30 % in the pelvis. Inadequate surgical margins are the most important reason. However, obtaining adequate margins is particularly difficult in this anatomically demanding region. Recently, three-dimensional (3-D) planning, printed models, and patient-specific instruments (PSI) with cutting blocks have been introduced to improve the precision during surgical tumor resection. This case series illustrates these modern 3-D tools in pelvic tumor surgery...
September 21, 2016: World Journal of Surgical Oncology
Kyle K VanKoevering, Scott J Hollister, Glenn E Green
Importance: Three-dimensional (3-D) printing is an exponentially growing technology that enables the use of a patient's image data to create patient-specific models, devices, and implants. Three-dimensional printing, developed in the 1980s, has emerged in the past decade with the potential to create new paradigms in personalized medicine. Observations: The field of otolaryngology has advanced many current and evolving future medical applications of 3-D printing...
October 6, 2016: JAMA Otolaryngology—Head & Neck Surgery
Tânia V Pinto, Paula Costa, Céu M Sousa, Carlos A D Sousa, Clara Pereira, Carla J S M Silva, Manuel Fernando R Pereira, Paulo J Coelho, Cristina Freire
Photochromic silica nanoparticles (SiO2@NPT), fabricated through covalent immobilization of silylated naphthopyrans based on 2H-naphtho[1,2-b]pyran (S1, S2) and 3H-naphtho[2,1-b]pyran (S3, S4) or through direct adsorption of parent naphthopyrans (NPT 1, 3) onto silica nanoparticles, were successfully incorporated onto cotton fabrics by screen-printing process. Two aqueous acrylic (AC) and polyurethane (PU)-based inks were used as dispersing media. All textiles exhibited reversible photochromism under UV and solar irradiation, developing fast response and intense coloration...
October 5, 2016: ACS Applied Materials & Interfaces
Rei Shiwaku, Yasunori Takeda, Takashi Fukuda, Kenjiro Fukuda, Hiroyuki Matsui, Daisuke Kumaki, Shizuo Tokito
Printed organic thin-film transistors (OTFTs) are well suited for low-cost electronic applications, such as radio frequency identification (RFID) tags and sensors. Achieving both high carrier mobility and uniform electrical characteristics in printed OTFT devices is essential in these applications. Here, we report on printed high-performance OTFTs and circuits using silver nanoparticle inks for the source/drain electrodes and a blend of dithieno[2,3-d;2',3'-d']benzo[1,2-b;4,5-b']dithiophene (DTBDT-C6) and polystyrene for the organic semiconducting layer...
October 4, 2016: Scientific Reports
Ambavaram Vijaya Bhaskar Reddy, Zulkifli Yusop, Jafariah Jaafar, Vemula Madhavi, Gajulapalle Madhavi
Drug discovery is a highly intricate, tedious and potentially rewarding approach associated with huge risk. Pharmaceutical companies literally spend millions of dollars to produce a single successful drug. The drug discovery process also needs firm compliance to directions on manufacturing and testing the drug standards before it comes into the market. All these considerations increase the demand to develop advanced approaches in drug discovery. The contributions of advanced technologies including high resolution analytical instruments, 3-D biological printing, next-generation sequencing and bioinformatics have made positive impact on drug discovery & development...
September 30, 2016: Current Drug Discovery Technologies
Andrew W Cairns, Raymond R Bond, Dewar D Finlay, Cathal Breen, Daniel Guldenring, Robert Gaffney, Anthony G Gallagher, Aaron J Peace, Pat Henn
INTRODUCTION: The 12-lead Electrocardiogram (ECG) presents a plethora of information and demands extensive knowledge and a high cognitive workload to interpret. Whilst the ECG is an important clinical tool, it is frequently incorrectly interpreted. Even expert clinicians are known to impulsively provide a diagnosis based on their first impression and often miss co-abnormalities. Given it is widely reported that there is a lack of competency in ECG interpretation, it is imperative to optimise the interpretation process...
September 26, 2016: Journal of Biomedical Informatics
Adam E Jakus, Alexandra L Rutz, Sumanas W Jordan, Abhishek Kannan, Sean M Mitchell, Chawon Yun, Katie D Koube, Sung C Yoo, Herbert E Whiteley, Claus-Peter Richter, Robert D Galiano, Wellington K Hsu, Stuart R Stock, Erin L Hsu, Ramille N Shah
Despite substantial attention given to the development of osteoregenerative biomaterials, severe deficiencies remain in current products. These limitations include an inability to adequately, rapidly, and reproducibly regenerate new bone; high costs and limited manufacturing capacity; and lack of surgical ease of handling. To address these shortcomings, we generated a new, synthetic osteoregenerative biomaterial, hyperelastic "bone" (HB). HB, which is composed of 90 weight % (wt %) hydroxyapatite and 10 wt % polycaprolactone or poly(lactic-co-glycolic acid), could be rapidly three-dimensionally (3D) printed (up to 275 cm(3)/hour) from room temperature extruded liquid inks...
September 28, 2016: Science Translational Medicine
Larry J Kricka
Several emerging or disruptive technologies can be identified that might, at some point in the future, displace established laboratory medicine technologies and practices. These include increased automation in the form of robots, 3-D printing, technology convergence (e.g., plug-in glucose meters for smart phones), new point-of-care technologies (e.g., contact lenses with sensors, digital and wireless enabled pregnancy tests) and testing locations (e.g., Retail Health Clinics, new at-home testing formats), new types of specimens (e...
August 2016: EJIFCC
D F Craft, W A Woodward, J Kanke, S Kry, R M Howell
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
J E Alpuche Aviles, D K Sasaki, M Jensen, D Rickey, A Dubey, C Harris, P McCowan, B McCurdy
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
A Dubey, K Johnson, D Sasaki, D Rickey, C Harris, T Boyer, J B Butler, A Leylek, A M Sharma, R Koul
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
Cassandra E Nelson, Nina R Beri, Jeffrey G Gardner
Physiological studies of recalcitrant polysaccharide degradation are challenging for several reasons, one of which is the difficulty in obtaining a reproducibly accurate real-time measurement of bacterial growth using insoluble substrates. Current methods suffer from several problems including (i) high background noise due to the insoluble material interspersed with cells, (ii) high consumable and reagent cost and (iii) significant time delay between sampling and data acquisition. A customizable substrate and cell separation device would provide an option to study bacterial growth using optical density measurements...
November 2016: Journal of Microbiological Methods
Miao Meng, Mehdi Kiani
Ultrasound has been recently proposed as an alternative modality for efficient wireless power transmission (WPT) to biomedical implants with millimeter (mm) dimensions. This paper presents the theory and design methodology of ultrasonic WPT links that involve mm-sized receivers (Rx). For given load (RL) and powering distance (d), the optimal geometries of transmitter (Tx) and Rx ultrasonic transducers, including their diameter and thickness, as well as the optimal operation frequency (fc) are found through a recursive design procedure to maximize the power transmission efficiency (PTE)...
September 20, 2016: IEEE Transactions on Biomedical Circuits and Systems
Woong Hee Lee, Hang Ren, Jianfeng Wu, Ondrej Novak, Richard B Brown, Chuanwu Xi, Mark E Meyerhoff
Herein, we report a novel design and the antimicrobial efficacy of a flexible nitric oxide (NO) releasing patch for potential wound healing applications. The compact sized polydimethylsiloxane (PDMS) planar patch generates NO via electrochemical reduction of nitrite ions mediated by a copper(II)-ligand catalyst using a portable power system and an internal gold coated stainless steel mesh working electrode. Patches are fabricated via soft lithography and 3-D printing. The devices can continuously release NO over 4 days and exhibit potent bactericidal effects on both Escherichia coli and Staphylococcus aureus...
September 12, 2016: ACS Biomaterials Science & Engineering
Joshua L Hermsen, Thomas M Burke, Stephen P Seslar, David S Owens, Beth A Ripley, Nahush A Mokadam, Edward D Verrier
OBJECTIVE: Static 3-dimensional printing is used for operative planning in cases that involve difficult anatomy. An interactive 3D print allowing deliberate surgical practice would represent an advance. METHODS: Two patients with hypertrophic cardiomyopathy had 3-dimensional prints constructed preoperatively. Stereolithography files were generated by segmentation of chest computed tomographic scans. Prints were made with hydrogel material, yielding tissue-like models that can be surgically manipulated...
August 20, 2016: Journal of Thoracic and Cardiovascular Surgery
Robert M Sweet
BACKGROUND: The challenges of training and assessing endourologic skill have driven the development of new training systems. The Center for Research in Education and Simulation Technologies (CREST) has developed a team and a methodology to facilitate this development process. METHODS: Backwards design principles were applied. A panel of experts first defined desired clinical and educational outcomes. Outcomes were subsequently linked to learning objectives. Gross task deconstruction was performed and the primary domain was classified as primarily involving decision-making, psychomotor skill or communication...
September 15, 2016: Journal of Endourology
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