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https://www.readbyqxmd.com/read/28740674/does-the-usage-of-digital-chest-drainage-systems-reduce-pleural-inflammation-and-volume-of-pleural-effusion-following-oncologic-pulmonary-resection-a-prospective-randomized-trial
#1
Michèle De Waele, John Agzarian, Waël C Hanna, Colin Schieman, Christian J Finley, Joseph Macri, Laura Schneider, Terri Schnurr, Forough Farrokhyar, Katherine Radford, Parameswaran Nair, Yaron Shargall
BACKGROUND: Prolonged air leak and high-volume pleural drainage are the most common causes for delays in chest tube removal following lung resection. While digital pleural drainage systems have been successfully used in the management of post-operative air leak, their effect on pleural drainage and inflammation has not been studied before. We hypothesized that digital drainage systems (as compared to traditional analog continuous suction), using intermittent balanced suction, are associated with decreased pleural inflammation and postoperative drainage volumes, thus leading to earlier chest tube removal...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28738216/early-time-related-course-of-image-findings-in-postmortem-mri-typical-findings-and-observer-agreement-in-a-porcine-model
#2
Frank Oliver Henes, Marc Regier, Peter Bannas, Marlen Henker, Axel Heinemann, Jan Sperhake, Philipp G C Begemann, Gerhard Adam, Michael Groth
PURPOSE: To assess early time-related image findings in postmortem magnetic resonance imaging (MRI) and to evaluate observer agreement in a porcine model. MATERIAL AND METHODS: Three pigs were examined by MRI at 15 different time points in the first 36h after death. Two observers independently recorded the postmortem interval (PMI) to the appearance of fluid collection (pleural space, interlobar and interlobular pulmonary fissures and hepatic interlobar fissures), gas accumulation (intrahepatic and intracardial) and blood clotting (aorta and intrahepatic venous vessels)...
July 15, 2017: Legal Medicine
https://www.readbyqxmd.com/read/28737858/the-effects-of-pneumococcal-conjugate-vaccine-pcv7-and-pcv13-on-turkish-children-with-invasive-pneumococcal-disease-a-single-center-experience
#3
Halil Özdemir, Caner Yıldız, Selin Nar Ötgün, Hatice Erkol, Adem Karbuz, Bilge Aldemir Kocabaş, Tuğçe Tural Kara, Ayşegül Gözalan, Rıza Durmaz, Ergin Çiftçi, Derya Aysev, Erdal İnce
INTRODUCTION: The aim of this prospective single-center study was to determine the changings in incidence of invasive pneumococcal disease (IPD), serotype distribution and the antimicrobial resistance patterns of S. pneumoniae in children with IPD after the period (1 to 7 years) of vaccination with PCV7 (2008) and PCV13 (2011). POPULATION AND METHODS: The study was conducted on 39 Turkish children with IPD between ages 1 month and 18 years in Ankara, Turkey. Streptococcus pneumoniae was identified using standard laboratory procedures from blood, cerebrospinal fluid (CSF), pleural fluid, and other sterile body fluids and tissues...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28736305/better-with-ultrasound-pleural-procedures-in-critically-ill-patients
#4
REVIEW
Scott J Millington, Seth Koenig
Procedures designed to drain fluid or air from the pleural spaces can be technically challenging in patients who are critically ill, and are associated with significant complications. Many individual ultrasound techniques have been described, each with the goal of making pleural drainage procedures safer. This article presents a systemic approach for incorporating many of these tools into procedures such as diagnostic thoracentesis, therapeutic drainage, or pleural catheter insertion. A series of illustrative figures and narrated video presentations are included to demonstrate many of the described techniques...
July 20, 2017: Chest
https://www.readbyqxmd.com/read/28728978/anticancer-drug-loaded-quantum-dots-engineered-polymeric-nanoparticles-diagnosis-therapy-combined-approach
#5
D Belletti, G Riva, M Luppi, G Tosi, F Forni, M A Vandelli, B Ruozi, F Pederzoli
Primary Effusion Lymphoma (PEL) is an HHV-8-related non Hodgkin lymphoma localized in body cavities (as pleural, peritoneal and pericardial) presenting lymphomatous effusion that, until now, lack of an effective therapy. Curcumin was reported to display pro-apoptotic effect via the inhibition of the JAK/STAT pathway, that is overexpressed in PEL cells, as consequence of virus infection. The administration of curcumin is severely restricted by its physicochemical properties, mainly its low solubility in biological fluid and consequently low bioavailability...
July 18, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28728273/-a-retrospective-study-of-the-perioperative-complications-following-whole-lung-lavage-in-the-treatment-of-pulmonary-alveolar-proteinosis
#6
Z Q Zhou, W L Guo, Y Chen, C H Zhong, S Y Li
Objective: To evaluate the safety of the procedures of whole lung lavage(WLL) for pulmonary alveolar proteinosis(PAP) in perioperative period. Methods: In this retrospective study, we collected clinical data from 78 WLL procedures of PAP patients from January 2006 to June 2016 in Guangzhou Institute of Respiratory Disease. The causes of perioperative complications were analyzed. Results: Eighteen (23.07%) of the 78 procedures developed complications, including pleural effusion(n=4), pneumonia(n=4), cardiac failure(n=2), cardiac arrhythmia (n=2), pneumothorax(n=2), atelectasis(n=1), lung edema(n=1), laryngeal edema(n=1), pleural effusion and pneumonia(n=1)...
July 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28727272/performance-of-clinical-prediction-rules-for-diagnosis-of-pleural-tuberculosis-in-a-high-incidence-setting
#7
Lely Solari, Alonso Soto, Patrick Van der Stuyft
OBJECTIVES: Diagnosis of pleural tuberculosis (PT) is still a challenge, particularly in resource- constrained settings. Alternative diagnostic tools are needed. We aimed at evaluating the utility of Clinical Prediction Rules (CPRs) for diagnosis of Pleural Tuberculosis (PT) in Peru. METHODS: We identified CPRs for diagnosis of PT through a structured literature search. CPRs using high-complexity tests, as defined by the FDA, were excluded. We applied the identified CPRs to patients with pleural exudates attending two third-level hospitals in Lima, Peru, a setting with high incidence of tuberculosis...
July 20, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28720600/is-the-mechanism-of-re-expansion-pulmonary-oedema-in-a-heart-lung-interaction
#8
Candy Masego Mokotedi, Martin Balik
The mechanism of re-expansion pulmonary oedema (Re-PE) is unclear. There are multiple variables in play when evaluating the response to evacuation of pleural fluid. We present an educational case of a critically ill patient admitted for respiratory failure who was fully dependent on ventricular pacing set at a constant rate throughout the episode of Re-PE. The transthoracic echocardiography (TTE) showed an ejection fraction of 38%, moderate mitral regurgitation (MR), mildly dilated right ventricle and moderate pulmonary hypertension...
July 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28719668/epidemiology-and-distribution-of-10-superantigens-among-invasive-streptococcus-pyogenes-disease-in-germany-from-2009-to-2014
#9
Matthias Imöhl, Christina Fitzner, Stephanie Perniciaro, Mark van der Linden
A nationwide laboratory-based surveillance study of invasive S. pyogenes infections was conducted in Germany. Invasive isolates (n = 719) were obtained between 2009 and 2014. Most isolates were obtained from blood (92.1%). The proportions of isolates from cerebrospinal fluid, pleural fluid, synovial fluid and peritoneal fluid were 3.9%, 1.8%, 1.7% and 0.6%, respectively. The most common emm types were emm 1 (31.8%), emm 28 (15.4%) and emm 89 (14.5%). The most common superantigen genes (speA, speC, speG, speH, speI, speJ, speK, speL, speM, ssa) identified from S...
2017: PloS One
https://www.readbyqxmd.com/read/28714265/can-malignant-and-inflammatory-pleural-effusions-in-dogs-be-distinguished-using-computed-tomography
#10
Thom C Watton, Ana Lara-Garcia, Christopher R Lamb
Computed tomography (CT) is the primary imaging modality used to investigate human patients with suspected malignant or inflammatory pleural effusion, but there is a lack of information about the clinical use of this test in dogs. To identify CT signs that could be used to distinguish pleural malignant neoplasia from pleuritis, a retrospective case-control study was done based on dogs that had pleural effusion, pre- and postcontrast thoracic CT images, and cytological or histopathological diagnosis of malignant or inflammatory pleural effusion...
July 16, 2017: Veterinary Radiology & Ultrasound
https://www.readbyqxmd.com/read/28712199/multimodality-imaging-approach-for-the-early-diagnosis-boerhaave-syndrome
#11
Javed Anwar, Rasikh Maqsood, Sanaullah Soomro
Boerhaave's syndrome is a spontaneous transmural rupture or perforation of the oesophagus or post-emesis oesophageal rupture. Boerhaave's syndrome has a high risk of morbidity and mortality, and early, definitive diagnosis leading to prompt management improves outcomes. Definitive diagnosis of this syndrome is made with imaging, including x-ray, USG and computed tomography Scan. This is a case of a 50-year male with history of sudden onset of epigastric pain after an episode of forceful emesis was referred for Ultrasound (USG) abdomen...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28710242/pseudomonas-aeruginosa-as-an-unusual-cause-of-cavitating-lung-lesion
#12
Justin D Salciccioli, Hannah Woodcock, Mathina Darmalingam
A 31-year-old woman with systemic lupus erythematosus presented to the emergency department with cough for 1 week. Chest radiograph demonstrated cavitating lesion in the right upper zone with surrounding ground-glass change. Blood culture results from the day of hospital presentation grew Pseudomonas aeruginosa Sputum sample and pleural fluid grew P. aeruginosa and were negative for acid-fast bacilli. P. aeruginosa is a rare cause of cavitating lung lesion and has been associated with immunocompromised hosts...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28708679/transpulmonary-pressure-describes-lung-morphology-during-decremental-positive-end-expiratory-pressure-trials-in-obesity
#13
Jacopo Fumagalli, Lorenzo Berra, Changsheng Zhang, Massimiliano Pirrone, Roberta R De Santis Santiago, Susimeire Gomes, Federico Magni, Glaucia A B Dos Santos, Desmond Bennett, Vinicius Torsani, Daniel Fisher, Caio Morais, Marcelo B P Amato, Robert M Kacmarek
OBJECTIVES: Atelectasis develops in critically ill obese patients when undergoing mechanical ventilation due to increased pleural pressure. The current study aimed to determine the relationship between transpulmonary pressure, lung mechanics, and lung morphology and to quantify the benefits of a decremental positive end-expiratory pressure trial preceded by a recruitment maneuver. DESIGN: Prospective, crossover, nonrandomized interventional study. SETTING: Medical and Surgical Intensive Care Units at Massachusetts General Hospital (Boston, MA) and University Animal Research Laboratory (São Paulo, Brazil)...
August 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28705799/rapid-developing-empyema-by-group-f-beta-streptococcus-anginosus-group
#14
Muhammad Azharuddin, Dy Prudence, Prem Shanker Shukla, Ajay Mathur
A 43-year-old male had progressive pleuritic left-sided chest tightness with shortness of breath. He had dental caries and tenderness on palpation of the left lateral chest. Complete blood count showed leucocytosis. CT scan of the chest with pulmonary emboli protocol showed multiple pulmonary nodules and nodular pleural thickening at left posterior lateral pleura. Forty-eight hours post CTPE scan, CT scan of the chest, abdomen and pelvis displayed right lower lobe consolidation and left-sided pleural effusion with superimposed compressive atelectasis...
July 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28700504/silent-presentation-of-multiple-metastasis-burkitt-lymphoma-in-a-child-a-case-report-and-review-of-the-literature
#15
REVIEW
Ingrith Miron, Lucian Miron, Vasile Valeriu Lupu, Ancuta Ignat
RATIONALE: The Burkitt lymphoma (BL) is a very aggressive B-cell non-Hodgkin's lymphoma. It accounts for 34% of lymphoma cases in children. PATIENT CONCERNS: We present the case of a 6-year-old boy diagnosed with BL, who presented multiple contrasting elements of the disease: silent symptomatology, without involvement of the bone marrow at first, but with multiorgan infiltration and a fast evolution, despite starting the treatment shortly after the symptoms appeared...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28681573/monomorphic-epitheliotropic-intestinal-t-cell-lymphoma-in-pleural-effusion-a-case-report
#16
F Antoniadou, A Dimitrakopoulou, P M Voutsinas, K Vrettou, I Vlahadami, M Voulgarelis, P Korkolopoulou, N Kafasi, P Mikou
Dissemination of lymphomas in serous effusions is quite common. Cytology aims to contribute in the clinical management of haematologic patients, providing an accurate and rapid diagnosis. Ancillary techniques such as immunocytochemistry and flow cytometry are essential to classify the lymphoma entity. Comprehensive awareness of the clinical picture and previous histologic documentation are essential for a lymphomatous effusion diagnosis. We report an unusual case of monomorphic epitheliotropic intestinal T-cell lymphoma, formerly known as enteropathy associated T-cell lymphoma (EATL) type II, spreading in the pleural cavity...
July 5, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28680698/non-iatrogenic-traumatic-isolated-bilothorax-in-a-cat
#17
Ronan A Mullins, Marc A Barandun, Barbara Gallagher, Laura C Cuddy
CASE SUMMARY: A 6-month-old spayed female domestic shorthair cat presented for evaluation of suspected bite wounds over the right caudal thorax and left cranial flank. Thoracic radiographs identified a mild right-sided pneumothorax, a small volume of right-sided pleural effusion, with increased soft tissue opacity in the right cranial and middle lung lobes. Abdominal ultrasound identified a very small gall bladder and several small pockets of free peritoneal fluid. Cytological analysis of peritoneal fluid was consistent with a modified transudate...
January 2017: JFMS open reports
https://www.readbyqxmd.com/read/28678571/therapeutical-effect-of-intrapleural-perfusion-with-hyperthermic-chemotherapy-on-malignant-pleural-effusion-under-video-assisted-thoracoscopic-surgery
#18
Xing Feng, Lucheng Zhu, Xiaoling Xiong, Hong Jiang, Zhibing Wu, Wen Meng, Yasi Xu, Shirong Zhang, Shenglin Ma
BACKGROUND: Patients with malignant pleural effusions (MPEs) have limited life expectancy. This study aims to investigate the feasibility of intrapleural perfusion with hyperthermic chemotherapy (IPHC) under video-assisted thoracoscopic surgery on MPE patients. METHODS: MPE patients were enrolled in the study and treated with IPHC. The treatment response was classified as complete response (CR, no re-accumulation of pleural fluid for 4 weeks), partial response (PR, re-accumulation above the post-IPHC level but below the pre-IPHC level for four weeks), no response (NR; re-accumulation or above the pre-IPHC level)...
July 5, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28676624/recurrent-pleural-effusion-secondary-to-a-pancreatic-pleural-fistula-treated-endoscopically
#19
Marco Antonio Bustamante Bernal, Jose Lisandro Gonzalez Martinez, Arleen Ortiz, Marc J Zuckerman
BACKGROUND Pancreatic-pleural fistula (PPF) is an uncommon complication of pancreatitis. Pleural effusions secondary to PPF are caused by fistulization of pancreatic secretions to the thorax derived from the rupture or leakage of a pseudocyst. CASE REPORT We describe the case of a 44-year-old male with recurrent right-sided pleural effusions and alcoholic pancreatitis who presented with epigastric pain and shortness of breath. Pleural fluid analysis revealed an amylase of 7002 U/lt. MRCP showed segmental narrowing and stricture of the proximal main pancreatic duct and an area of walled-off necrosis...
July 5, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28674714/genexpert-technology-a-breakthrough-for-the-diagnosis-of-tuberculous-pericarditis-and-pleuritis-in-less-than-2-hours
#20
Muhammad Saeed, Mobeen Ahmad, Shagufta Iram, Saba Riaz, Mehwish Akhtar, Maleeha Aslam
OBJECTIVES: To evaluate the diagnostic validity of GeneXpert for the detection of Mycobacterium tuberculosis (MTB) in pericardial and pleural effusions samples. METHODS: A cross sectional study was conducted at the Mycobacteriology Laboratory, Allama Iqbal Medical College, Lahore, Pakistan. A total of 286 (158 pleural and 128 pericardial fluids) samples were received from tuberculosis (TB) suspects between January 2014 and August 2016. Every sample was processed for Ziehl-Neelsen (Zn) smear, Lowenstein Jensen (LJ) culture, GeneXpert MTB/RIF assay according to standard protocols...
July 2017: Saudi Medical Journal
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