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https://www.readbyqxmd.com/read/28078172/gastric-rupture-in-pregnancy-case-series-from-a-tertiary-institution-in-rwanda-and-review-of-the-literature
#1
David Ntirushwa, Stephen Rulisa, Febronie Muhorakeye, Lisa Bazzett-Matabele, Theogene Rurangwa, Maria Small
Background Gastric rupture is a rare, life-threatening condition during pregnancy. Case study We present three cases of gastric perforation during pregnancy and the puerperium. The first patient presented with gastric perforation 4 days following an uncomplicated cesarean delivery for obstetric indications. She initially complained of epigastric pain; however, those symptoms resolved. She later demonstrated worsening abdominal distension, intra-abdominal free fluid, and signs of peritonitis. At laparotomy, an ascariasis-associated gastric rupture was diagnosed...
October 2016: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28074870/microrna-155-is-upregulated-in-ascites-in-patients-with-spontaneous-bacterial-peritonitis
#2
Philipp Lutz, Mohamed M Haimid, Alessandra Pohlmann, Jennifer Lehmann, Christian Jansen, Robert Schierwagen, Sabine Klein, Christian P Strassburg, Ulrich Spengler, Jonel Trebicka
MircoRNA's (miR) have been recognised as important modulators of gene expression and potential biomarkers. However, they have been rarely investigated in bio fluids apart from blood. We investigated the association of miR-125b and miR-155 with complications of cirrhosis. Ascites was prospectively collected from patients with cirrhosis undergoing paracentesis at our department. miR's were determined in the supernatant using qPCR and normalized by SV-40. Clinical parameters were assessed at paracentesis and during follow-up...
January 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28063824/development-of-safe-and-potent-o-w-emulsion-of-paclitaxel-to-treat-peritoneal-dissemination
#3
Ken-Ichi Ogawara, Yoshiko Fukuoka, Yuta Yoshizawa, Toshikiro Kimura, Kazutaka Higaki
To develop a safer and more potent paclitaxel (PTX) formulation, we prepared various O/W emulsions by using egg phosphatidylcholine, Tween 80, and a mixture of triglycerides with different fatty acid chain lengths as the co-surfactant, surfactant, and oil phase component, respectively. The mean particle diameters of the PTX-emulsions prepared were around 100 nm. The PTX-emulsions did not provoke histamine release from rat mast cells and did not show any significant hemolytic activity, suggesting that PTX-emulsions are biocompatible...
January 4, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28057913/humoral-hypercalcemia-in-uterine-cancers-a-case-report-and-literature-review
#4
Vijeyaluxmy Motilal Nehru, Gwenalyn Garcia, Juan Ding, Fanyi Kong, Qun Dai
BACKGROUND Paraneoplastic hypercalcemia is a well-described complication associated with a variety of malignancies. However, its incidence in gynecological malignancies is low. CASE REPORT A 53-year-old woman presented with progressive abdominal distention and irregular vaginal bleeding of several weeks' duration. A contrast CT abdomen and pelvis was significant for a mass in the lower uterine/cervical region, multiple peritoneal and omental masses, enlarged pelvic and paraaortic lymph nodes, and large-volume ascites...
January 6, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28057514/systemic-effects-of-subtilase-cytotoxin-produced-by-escherichia-coli-o113-h21
#5
E Abril Seyahian, Gisela Oltra, Federico Ochoa, Santiago Melendi, Ricardo Hermes, James C Paton, Adrienne W Paton, Nestor Lago, Mauricio Castro Parodi, Alicia Damiano, Cristina Ibarra, Elsa Zotta
: Subtilase cytotoxin (SubAB) is a member of the AB5 cytotoxin family and is produced by certain strains of Shiga toxigenic Escherichia coli. The toxin is known to be lethal to mice, but the pathological mechanisms that contribute to Uremic Hemolytic Syndrome (HUS) are poorly understood. In this study we show that intraperitoneal injection of a sublethal dose of SubAB in rats triggers a systemic response, with ascitic fluid accumulation, heart hypertrophy and damage to the liver, colon and kidney...
January 2, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28043912/ultrasound-mediated-destruction-of-oxygen-and-paclitaxel-loaded-dual-targeting-microbubbles-for-intraperitoneal-treatment-of-ovarian-cancer-xenografts
#6
Tingting Luo, Jiangchuan Sun, Shenyin Zhu, Juan He, Lan Hao, Linlin Xiao, Yi Zhu, Qianqian Wang, Xin Pan, Zhigang Wang, Shufang Chang
Folate receptor (FR) is overexpressed in many epithelial cancers and tumor-associated macrophages (TAMs), which enable it to function as an appropriate target for cancer treatment. We have successfully synthesized multifunctional folate-targeted and oxygen/paclitaxel loaded microbubbles (TOPLMBs) for ultrasound (US) mediated delivery for combination therapy in an intraperitoneal ovarian cancer xenograft model. The TOPLMBs target both ovarian cancer cells and TAMs and provide a promising drug delivery strategy for the combination treatment of ovarian cancer and tumor microenvironment...
December 30, 2016: Cancer Letters
https://www.readbyqxmd.com/read/28043549/effect-of-time-duration-of-digestion-decontamination-technique-on-yield-of-mycobacteria-and-contamination-rates-from-sterile-body-fluids-pleural-and-ascitic-fluid-and-pus-specimens
#7
Samreen Shafiq, Faryal Saleem, Kauser Jabeen, Joveria Farooqi, Warda Alam, Sadia Hanif, Shazia Ali, Sadia Shakoor, Rumina Hasan
BACKGROUND: Duration of digestion/decontamination has a considerable impact on yield of mycobacteria especially from sterile body fluids and pus specimens. Additionally, duration of digestion/decontamination affects the contamination rates. This study evaluates the effect of digestion/decontamination protocol for 15 and 20min versus inoculation of media directly from the sample on contamination rates as well as the yield of mycobacteria from pus and sterile fluids other than cerebrospinal fluids...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28042217/performance-of-xpert-mtb-rif-on-ascitic-fluid-samples-for-detection-of-abdominal-tuberculosis
#8
Syed Beenish Rufai, Sarman Singh, Amit Singh, Parveen Kumar, Jitendra Singh, Anand Vishal
BACKGROUND: Diagnosis of abdominal tuberculosis (TB) from ascitic fluid samples using routinely available diagnostic methods is challenging due to its paucibacillary nature. Although performance of Xpert MTB/RIF assay has been evaluated extensively on pulmonary samples, its performance on extrapulmonary samples is still under evaluation. OBJECTIVES: The objective of this study was to find out the performance of Xpert MTB/RIF on ascitic fluid samples obtained from suspected cases of abdominal TB...
January 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28029208/pulmonary-and-tricuspid-valvuloplasty-in-carcinoid-heart-disease
#9
Ashkan Karimi, Negiin Pourafshar, James C Fudge
A 26-year-old female with carcinoid heart disease consisting of severe pulmonary and tricuspid valve stenosis was admitted with line associated sepsis. She recovered from sepsis with antibiotics and aggressive fluid resuscitation but became grossly volume overloaded with evidence of tense ascites and lower extremity edema. She developed worsening renal and hepatic function due to congestive nephropathy and hepatopathy, which did not respond to intravenous diuretics, and she was deemed too sick for surgical pulmonary and tricuspid valve replacement...
December 28, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28026995/scale-up-production-and-characterization-of-anti-human-cardiac-troponin-i-monoclonal-antibody-in-ascitic-fluid-of-balb-c-mice
#10
Asiabanha Rezaee Majid, Rasaee Mohammad Javad, Paknejad Malihe, Mohammadnejad Javad
The Human Cardiac Troponin I (hcTnI) is a 210 amino acid protein, 23 kDa in molecular weight. This biomarker is commonly used to diagnose myocardial infarction, micro injury, and acute coronary syndrome (ACS) in patients referring to emergency departments. The American Heart Association (AHA) and European Society of Cardiology (ESC) proposed troponin I as the gold biomarker for early detection of heart attack, especially in myocardial infarction (MI). Therefore, developing monoclonal antibodies against this biomarker could help in for early detection of heart attack...
December 27, 2016: Journal of Immunoassay & Immunochemistry
https://www.readbyqxmd.com/read/27994338/chylous-ascites-in-advanced-gallbladder-cancer
#11
Mallika Tewari, Rupesh Singh, H S Shukla
Chylous ascites is a very rare occurrence in a patient with gallbladder cancer (GBC), and only six cases have been reported. We report here one such case in a 55-year-old lady who presented to us with upper abdominal pain for 6 months. A polypoidal gallbladder mass with minimal liver invasion but with multiple subcentimeter pericholedochal, common hepatic, mesenteric, and para-aortic lymph nodes was found on contrast-enhanced computed tomography scan. At laparotomy, the abdomen had milky fluid with engorged beaded lymphatics all over the small intestine...
October 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/27987334/echocardiography-findings-in-a-case-with-ballantyne-syndrome
#12
Yutaro Suzuki, Mie Yamamura, Keisuke Kikuchi, Rifumi Hattori, Takeshi Umazume, Hisanori Minakami
Marked fluid retention occurs in Ballantyne syndrome, but few reports are available on changes in cardiac morphology in this syndrome. A woman with generalized edema, dyspnea, fetal hydrops (skin edema and ascites), thickened placenta, and elevated plasma B-type natriuretic peptide level (344 pg/mL) was admitted to our hospital at gestational week (GW) 20(+3) . Blood pressure remained within the normal range. However, acute increases in left atrial volume index, pulmonary artery systolic pressure, and hyperdynamic left ventricular function (as evidenced by increased left ventricular ejection fraction to 74% with cardiac index of 5...
December 17, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27986362/acute-focal-bacterial-nephritis-in-a-cohort-of-hospitalized-adult-patients-with-acute-pyelonephritis-assessment-of-risk-factors-and-a-predictive-model
#13
Joaquin Campos-Franco, Cristina Macia, Emilio Huelga, Carla Diaz-Louzao, Francisco Gude, Rosario Alende, Arturo Gonzalez-Quintela
BACKGROUND: Acute focal bacterial nephritis (AFBN) is a complicated form of acute pyelonephritis (APN) characterized by single or multiple areas of localised infection in the kidney without liquefaction or abscess. Studies investigating AFBN in adults are scarce. AIM: The present study was aimed at evaluating the prevalence, associated factors, and presence of atypical clinical and radiological manifestations in adult AFBN patients. Also, we developed a clinical prediction model to evaluate the probability of AFBN in patients with APN...
December 13, 2016: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/27979645/abdominal-cerebrospinal-fluid-pseudocyst-masquerading-as-ascites-in-an-adolescent-girl
#14
Raymond C Stetson, Kiran A Goyal, Benjamin J Sandefur
No abstract text is available yet for this article.
December 12, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27938534/chyloperitoneum-associated-with-idiopathic-pancreatitis-case-report-and-review-of-the-literature
#15
G D'Amata, M Rega, V Viola, V Bove, P Simeone, G Baiano
Acute chylous peritonitis is defined as the onset of acute abdomen findings due to abrupt chylous fluid accumulation in the peritoneal space. A correct diagnosis of this condition is seldom made preoperatively. The optimal management of true chylous pancreatitis depends upon the underlying etiology. Thorough lavage of the abdomen and adequate drainage has proven to be an excellent treatment modality for acute chylous peritonitis, since resolution of chylous ascites usually occurs within the next few days. However, conservative treatment may be appropriate in selected cases...
July 2016: Il Giornale di Chirurgia
https://www.readbyqxmd.com/read/27935910/ascites-and-adnexal-mass-with-raised-ca125-how-arduous-can-be-the-path-of-diagnosis
#16
D Pannu, S Malik, S Shamsunder, A Bhatnagar
Ascites, adnexal mass and elevated CA125 levels almost always suggest advanced ovarian carcinoma. We present a case of a 37 years old multiparous lady who presented with such a classical picture. Radiological picture was suggestive of ovarian carcinoma with peritoneal metastasis. However, ascitic fluid cytology was negative for malignant cells. A differential diagnosis of tubercular mass was made. Ascitic fluid was sent for adenosine deaminase test that was negative. Fine needle aspiration cytology failed to reveal any sufficient sample for evaluation...
January 2016: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/27900975/renal-fluid-overload-diagnosed-by-retinal-optical-coherence-tomography-scanning
#17
Sunny M Kar, Thanh-Giao Nguyen, Sneha Rathod, Saad Shaikh, Pran M Kar
Fluid overload is one of the major findings in patients with end-stage renal disease. Common findings in fluid overload include shortness of breath, pedal edema, ascites, and pericardial effusion. Rarely, vision loss can be associated with decompensated systemic fluid status. In the following case, we report an unusual case of vision loss due to retinal edema as a result of fluid overload diagnosed and followed to resolution by optical coherence tomography testing.
November 2016: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/27900084/sister-mary-joseph-nodule-caused-by-metastatic-desmoplastic-small-round-cell-tumor-a-clinicopathological-report
#18
Noppadol Larbcharoensub, Atcharaporn Pongtippan, Duangjai Pangpunyakulchai, Sith Phongkitkarun, Panuwat Lertsithichai, Thitiya S Dejthevaporn
Sister Mary Joseph nodule is an uncommon metastatic intra-abdominal malignancy involving the umbilicus. The present study describes a rare case of desmoplastic small round cell tumor (DSRCT), histological grade 3, high grade, Gilly classification 4, stage IV, in an 18-year-old Thai man presenting with the Sister Mary Joseph nodule, ascites and pleural effusion. The histopathological examination of the umbilical mass revealed the presence of malignant small round cells associated with prominent stromal desmoplasia...
November 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27895818/case-of-pseudo-meigs-syndrome-caused-by-gastric-cancer-related-metastatic-ovarian-tumor-with-prolonged-survival
#19
Masaru Okamoto, Kazunori Maeda, Atsushi Yanagitani, Kiwamu Tanaka
A 48-year-old woman presented with bilateral enlarged ovaries, ascites, bilateral pleural effusion, and advanced gastric cancer. Pleural fluid cytology did not reveal malignant cells. Oophorectomy, performed as a palliative procedure, was followed by rapid resolution of the pleural effusion and ascites. The patient was diagnosed with pseudo-Meigs' syndrome, and underwent chemotherapy followed by partial gastrectomy. At the last follow-up, 84 mo following oophorectomy, she was alive, and free of disease recurrence, despite not receiving any further treatment...
November 15, 2016: World Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/27894167/salinomycin-reduces-stemness-and-induces-apoptosis-on-human-ovarian-cancer-stem-cell
#20
Hyun Gyo Lee, So Jin Shin, Hye Won Chung, Sang Hoon Kwon, Soon Do Cha, Jin Eui Lee, Chi Heum Cho
OBJECTIVE: Cancer stem cells (CSCs) represent a subpopulation of undifferentiated tumorigenic cells thought to be responsible for tumor initiation, maintenance, drug resistance, and metastasis. The role of CSCs in drug resistance and relapse of cancers could significantly affect outcomes of ovarian cancer patient. Therefore, therapies that target CSCs could be a promising approach for ovarian cancer treatment. The antibiotic salinomycin has recently been shown to deplete CSCs. In this study, we evaluated the effect of salinomycin on ovarian cancer stem cells (OCSCs), both alone and in combination with paclitaxel (PTX)...
November 14, 2016: Journal of Gynecologic Oncology
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