keyword
https://read.qxmd.com/read/38418639/evaluation-of-changes-in-macular-structures-after-subthreshold-micropulse-laser-therapy-on-chronic-central-serous-chorioretinopathy
#21
JOURNAL ARTICLE
Lijun Liu, Qian Xu, Xian Song, Yuqing Zhao, Yu Zhang, Yi Qu
PURPOSE: To evaluate the changes in macular structures following subthreshold micropulse laser (SHML) treatment for chronic central serous chorioretinopathy (cCSC). METHODS: Data of 33 eyes from 31 cCSC patients treated with SHML and followed up for at least 6 months has been included in this retrospective study. Main outcome measurements include resolution of subretinal fluid (SRF) and pigment epithelial detachment (PED), the recovery of ellipsoid zone (EZ) continuity, and the foveal outer nuclear layer (ONL) thickness along with its ratio...
February 29, 2024: Lasers in Medical Science
https://read.qxmd.com/read/38406665/crossover-to-pdt-after-the-unsuccessful-micropulse-laser-treatment-of-central-serous-chorioretinopathy
#22
JOURNAL ARTICLE
Maciej Gawęcki, Krzysztof Kiciński, Andrzej Grzybowski
PURPOSE: Subthreshold micropulse laser (SML) and photodynamic therapy (PDT) are among the most effective therapeutic modalities applied to central serous chorioretinopathy (CSCR). This study aimed to evaluate the efficacy and durability of PDT in CSCR cases unresponsive to at least two SML treatments. METHODS: The study included 26 consecutive eyes of 24 patients (21 males and three females) with chronic CSCR. In all cases, a lack of reduction in subretinal fluid (SRF) levels was noted after at least two consecutive SML sessions...
2024: Adv Ophthalmol Pract Res
https://read.qxmd.com/read/38398376/effect-of-focal-laser-photocoagulation-on-the-ganglion-cell-complex-thickness-in-acute-central-serous-chorioretinopathy
#23
JOURNAL ARTICLE
A Young Lee, Jinyoung Choi, Sang Un Lee, Chul Woo Kim, Daniel Duck-Jin Hwang
This study investigated the changes in the ganglion cell complex (GCC) of patients with acute central serous chorioretinopathy (CSC) following focal laser photocoagulation (FLP) and sought to determine its correlation with visual acuity (VA). Our retrospective study was conducted on 30 patients diagnosed with acute CSC between January 2015 and April 2022, who underwent FLP within 3 months of symptom onset. The study assessed GCC changes by measuring the thickness of its inner retinal layers-retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), and inner plexiform layer (IPL) using optical coherence tomography (OCT)...
February 13, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38381619/bilaterally-subluxed-diffractive-intraocular-lenses-big-expectations-and-even-bigger-comorbidities
#24
JOURNAL ARTICLE
Nicole R Fram, Ehud Assia, Nandini Venkateswaran, John Morgan Micheletti, Brian Shafer, Iqbal Ike K Ahmed, Julie M Schallhorn, Jay M Stewart
A 78-year-old woman with an ocular history of cataract surgery with a diffractive intraocular lens (IOL) in each eye has developed fluctuating vision, greater in the right eye than the left eye, after 4 years. She has a history of inactive central serous retinopathy and a vision potential of 20/25 + 2 in the right eye and 20/25 in the left eye. She has well-controlled diabetes, hypertension, and hypercholesterolemia. She has enjoyed her spectacle independence for some time and wishes to have her vision restored...
March 1, 2024: Journal of Cataract and Refractive Surgery
https://read.qxmd.com/read/38376085/mitogen-activated-pathway-kinase-inhibitor-associated-retinopathy-do-features-differ-with-upstream-versus-downstream-inhibition
#25
JOURNAL ARTICLE
Jasmine H Francis, William Foulsham, Julia Canestraro, James J Harding, Eli L Diamond, Alexander Drilon, David H Abramson
INTRODUCTION: Many cancers have derangement of the mitogen-activated pathway kinase (MAPK), making this pathway blockade a therapeutic target. However, inhibitors of MAPK can result in adverse effects including retinopathy. This study compares clinical and morphological characteristics of serous retinal disturbances in patients taking agents with variable inhibition of MAPK: either direct interference of mitogen-activated protein kinase kinase (MEK) or extracellular signal-regulated kinase (ERK) inhibitors or with indirect inhibition via interference with FGFR signaling...
August 2023: Ocular Oncology and Pathology
https://read.qxmd.com/read/38374948/peripapillary-retinal-neovascularization-and-vitreous-hemorrhage-secondary-to-peripapillary-pachychoroid-syndrome
#26
Imène Zhioua Braham, Mejdi Boukari, Rim Maalej, Ilhem Mili, Raja Zhioua
PURPOSE: To report a case of peripapillary pachychoroid syndrome (PPS) complicated with peripapillary retinal neovascularization causing vitreous hemorrhage. OBSERVATION: A 42-year-old man, with a history of a visual loss of the right eye (RE) for 4 years, presented for ophthalmological examination. Best-corrected visual acuity was «counting fingers» in the RE and 20/25 in the left eye. Fundus examination showed irregular pattern of hypopigmentation of the retinal pigmented epithelium in both eyes with retinal neovessels in the peripapillary region of the RE...
March 2024: American Journal of Ophthalmology Case Reports
https://read.qxmd.com/read/38343245/intra-and-inter-expert-validation-of-an-automatic-segmentation-method-for-fluid-regions-associated-with-central-serous-chorioretinopathy-in-oct-images
#27
JOURNAL ARTICLE
Mateo Gende, Lúa Castelo, Joaquim de Moura, Jorge Novo, Marcos Ortega
Central Serous Chorioretinopathy (CSC) is a retinal disorder caused by the accumulation of fluid, resulting in vision distortion. The diagnosis of this disease is typically performed through Optical Coherence Tomography (OCT) imaging, which displays any fluid buildup between the retinal layers. Currently, these fluid regions are manually detected by visual inspection a time-consuming and subjective process that can be prone to errors. A series of six deep learning-based automatic segmentation architectural configurations of different levels of complexity were trained and compared in order to determine the best model intended for the automatic segmentation of CSC-related lesions in OCT images...
January 12, 2024: J Imaging Inform Med
https://read.qxmd.com/read/38327706/case-report-page-kidney-with-multiple-serosal-effusions-caused-by-bilateral-spontaneous-renal-subcapsular-hemorrhage
#28
Leibo Wang, Zuze Qiu, Shun Zhan, Guanyu Shi, Wei He, Zhuangding Cen, Feng Xu, Wu Tian, Daobing Li
Page kidney is caused by the perirenal or subcapsular accumulation of blood or fluid pressing on the renal parenchyma and is a rare cause of secondary hypertension. In this study, we report a case of Page caused by bilateral spontaneous subcapsular renal hematoma, the main manifestations of which were secondary hypertension, multiple serous effusions, and renal insufficiency. After admission, drug blood pressure control was ineffective. After bilateral perirenal effusion puncture and drainage were performed to relieve bilateral perirenal compression, blood pressure gradually dropped to normal, multi-serous cavity effusion (pericardial, thoracic, and abdominal effusion) gradually disappeared, and kidney function returned to normal...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38318574/curious-case-of-a-giant-retroperitoneal-cyst
#29
Viral Surani, Sanjay Chatterjee, Sunila Jaggi, Niranjan Banka, Shivani Desai, Gajanan Rodge
Adrenal cysts are uncommon fluid-filled masses that develop in the adrenal gland. Typically, they are non-functional, asymptomatic, and smaller than 10 cm in diameter when incidentally detected. However, the presence of giant adrenal cysts, exceeding 10 cm in diameter, creates a diagnostic challenge due to the difficulty in determining their origin. Surgical intervention is advised when the cyst surpasses 10 cm in diameter, produces symptoms, causes endocrine abnormalities, exhibits intracystic bleeding, or raises suspicion of malignancy...
January 2024: Curēus
https://read.qxmd.com/read/38311164/nkx2-3-transcription-factor-is-a-key-regulator-of-mucous-cell-identity-in-salivary-glands
#30
JOURNAL ARTICLE
Xin Gao, Taro Mukaibo, Xiaolu Wei, Roberta C Faustoferri, Maria S Oei, Seo-Kyoung Hwang, Adela Jingyi Yan, James E Melvin, Catherine E Ovitt
Saliva is vital to oral health, fulfilling multiple functions in the oral cavity. Three pairs of major salivary glands and hundreds of minor salivary glands contribute to saliva production. The secretory acinar cells within these glands include two distinct populations. Serous acinar cells secrete a watery saliva containing enzymes, while mucous acinar cells secrete a more viscous fluid containing highly glycosylated mucins. Despite their shared developmental origins, the parotid gland (PG) is comprised of only serous acinar cells, while the sublingual gland (SLG) contains predominantly mucous acinar cells...
February 2, 2024: Developmental Biology
https://read.qxmd.com/read/38310296/chylopericardium-following-esophagectomy-a-case-report-and-systematic-review
#31
JOURNAL ARTICLE
Xinglin Yang, Jinghong Zhang, Pengxia Sun, Jihai Liu, Jiangshan Wang, Huadong Zhu
BACKGROUND: Chylopericardium is a rare condition characterized by the accumulation of chyle in the pericardial space. It is most commonly caused by thoracic duct injury. Chylopericardium following esophagectomy is extremely rare but can cause life-threatening complications. This report presents a case of chylopericardium post-esophagectomy, resulting in cardiac tamponade and cardiac arrest. A systematic literature review was also conducted to facilitate the understanding of this rare condition...
February 3, 2024: Journal of Cardiothoracic Surgery
https://read.qxmd.com/read/38301969/central-serous-chorioretinopathy-an-evidence-based-treatment-guideline
#32
REVIEW
Helena M A Feenstra, Elon H C van Dijk, Chui Ming Gemmy Cheung, Kyoko Ohno-Matsui, Timothy Y Y Lai, Hideki Koizumi, Michael Larsen, Giuseppe Querques, Susan M Downes, Suzanne Yzer, Mark P Breazzano, Yousif Subhi, Ramin Tadayoni, Siegfried G Priglinger, Laurenz J B Pauleikhoff, Clemens A K Lange, Anat Loewenstein, Roselie M H Diederen, Reinier O Schlingemann, Carel B Hoyng, Jay K Chhablani, Frank G Holz, Sobha Sivaprasad, Andrew J Lotery, Lawrence A Yannuzzi, K Bailey Freund, Camiel J F Boon
Central serous chorioretinopathy (CSC) is a relatively common disease that causes vision loss due to macular subretinal fluid leakage and is often associated with reduced vision-related quality of life. In CSC, the leakage of subretinal fluid through defects in the retinal pigment epithelial layer's outer blood-retina barrier appears to occur secondary to choroidal abnormalities and dysfunction. The treatment of CSC is currently the subject of controversy, although recent data obtained from several large randomized controlled trials provide a wealth of new information that can be used to establish a treatment algorithm...
January 31, 2024: Progress in Retinal and Eye Research
https://read.qxmd.com/read/38288177/risks-and-management-of-central-serous-chorioretinopathy-in-a-middle-aged-female
#33
Reshma Annam, Pravallika Padyala, Preethi Annam, Sailaja Nandennagari, Krupavaram Bethala
Central serous chorioretinopathy (CSC) is the buildup of fluid in the posterior pole distorting the vision resulting from either neurosensory or retinal pigment epithelial detachment. This is a case report of a 33-year-old female complaining of cloudiness in the left eye who was subsequently diagnosed with CSC using optical coherence tomography (OCT). Remission was observed in four months, possibly from ocular drop treatment or spontaneous. Our case report is unique as the incidence of CSC is more common in males, almost six times higher than in females...
December 2023: Curēus
https://read.qxmd.com/read/38281567/scleral-thickness-in-simple-versus-complex-central-serous-chorioretinopathy-scleral-thickness-in-simple-versus-complex-csc
#34
JOURNAL ARTICLE
Naoya Imanaga, Nobuhiro Terao, Sorako Wakugawa, Yasunori Miyara, Shota Sawaguchi, Ayano Oshiro, Yukihide Yamauchi, Hideki Koizumi
PURPOSE: To evaluate the association between scleral thickness and a newly developed multimodal imaging-based classification of central serous chorioretinopathy (CSC). DESIGN: Retrospective, cross-sectional study. METHODS: This study included 217 eyes of 217 patients classified as simple or complex CSC based on the established protocols. Clinical and anatomical factors were compared between the two types. The scleral thickness was measured at four locations using anterior-segment optical coherence tomography...
January 26, 2024: American Journal of Ophthalmology
https://read.qxmd.com/read/38272519/alirocumab-associated-unilateral-posterior-uveitis
#35
JOURNAL ARTICLE
Ehinomen Sarah Inegbedion, Matthew Azzopardi, Tracey Inessa, Yu Jeat Chong
A man in his mid-40s who had been recently started on alirocumab (a human monoclonal antibody which inhibits proprotein convertase subtilisin/kexin type 9) due to his strong familial cardiovascular risk and refractory hypercholesterolaemia presented with a few-hour history of acute-onset left-sided blurred vision. The best-corrected visual acuities were 6/6 bilaterally and slit-lamp examination was normal. However, optical coherence tomography revealed serous subretinal fluid in the left macula. Optos ultra-widefield retinal imaging and fundus autofluorescence, along with a set of blood tests, did not reveal any alternative causes...
January 24, 2024: BMJ Case Reports
https://read.qxmd.com/read/38270124/intravitreal-brolucizumab-for-chronic-central-serous-chorioretinopathy-without-choroidal-neovascular-membrane-a-pilot-study
#36
JOURNAL ARTICLE
Srishti Raksheeth Ramamurthy, Umesh Chandra Behera, Ritesh Narula, SriniVas R Sadda, Raja Narayanan
PURPOSE: To study intravitreal brolucizumab in the management of persistent macular fluid in chronic central serous chorioretinopathy (CSCR) without choroidal neovascular membrane (CNVM). METHODS: Retrospective case series which included eyes with chronic CSCR with persistent macular fluid for ≥ 3 months without CNVM. Intravitreal brolucizumab was administered in all eyes. Primary outcome measure was the resolution of intraretinal (IRF) and/or subretinal fluid (SRF) on OCT...
January 25, 2024: Seminars in Ophthalmology
https://read.qxmd.com/read/38263930/transcriptome-analysis-of-choroidal-endothelium-links-androgen-receptor-role-to-central-serous-chorioretinopathy
#37
JOURNAL ARTICLE
Sandrine H Künzel, Dominika Pohlmann, Lynn Zur Bonsen, Matteus Krappitz, Oliver Zeitz, Antonia M Joussen, Alexandre Dubrac, Steffen E Künzel
BACKGROUND: Central Serous Chorioretinopathy (CSCR) manifests as fluid accumulation between the neurosensory retina and the retinal pigment epithelium (RPE). Elevated levels of steroid hormones have been implicated in CSCR pathogenesis. This investigation aims to delineate the gene expression patterns of CSCR-associated risk and steroid receptors across human choroidal cell types and RPE cells to discern potential underlying mechanisms. METHODS: This study utilized a comprehensive query of transcriptomic data derived from non-pathological human choroid and RPE cells...
January 24, 2024: European Journal of Ophthalmology
https://read.qxmd.com/read/38254230/serous-maculopathy-with-absence-of-retinal-pigment-epithelium-smarpe-associated-with-large-drusen
#38
JOURNAL ARTICLE
Luiz H Lima, João Pedro Romero Braga, Gustavo B Melo, Wener P Cella, Adam S L Brandão, Rodrigo L Meirelles, Claudio Zett, Francyne V R Cyrino, Rodrigo Jorge
PURPOSE: To describe the association of serous maculopathy with absence of retinal pigment epithelium (SMARPE) and large drusen in patients with non-neovascular age-related macular degeneration (AMD). METHODS: A retrospective study of ophthalmic examination and multimodal imaging data of individuals with SMARPE and large drusen observed over a period of 12-month was accomplished. SMARPE was defined as subretinal accumulation of fluid within the macular area due to retinal pigment epithelium (RPE) aperture...
January 22, 2024: International Journal of Retina and Vitreous
https://read.qxmd.com/read/38253572/selective-retina-therapy-with-real-time-feedback-controlled-technology-in-central-serous-chorioretinopathy-a-24-month-follow-up-real-world-prospective-study
#39
JOURNAL ARTICLE
Chang Ki Yoon, Hyeong Gon Yu
OBJECTIVE: Although central serous chorioretinopathy (CSC) treatment using selective retinal therapy (SRT) has presented favourable outcomes, no long-term studies with a real-world clinical practice regimen have been conducted. METHODS AND ANALYSIS: We performed a long-term assessment of CSC treatment using SRT with real-time feedback (RTF) technology. 50 patients (53 eyes) with CSC and more than a 1-month symptom duration were recruited and treated with SRT using a 1...
January 22, 2024: BMJ Open Ophthalmology
https://read.qxmd.com/read/38235944/rapid-diurnal-variation-of-serous-retinal-detachment-during-braf-and-mek-inhibitor-treatment-a-case-series
#40
JOURNAL ARTICLE
Giorgio Enrico Bravetti, Kevin Muggler, Assma Ben Aissa, Gabriele Thumann, Ariane Malclès
No abstract text is available yet for this article.
January 18, 2024: Acta Ophthalmologica
keyword
keyword
52401
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.