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https://www.readbyqxmd.com/read/28712034/recurrence-of-acute-lymphoblastic-leukemia-manifesting-as-serous-retinal-detachments-and-optic-disc-swelling
#1
Ozge Yabas Kiziloglu, Mert Mestanoglu, Ozgun Melike Totuk Gedar, Cafer Adiguzel, Okan Toygar
PURPOSE: The aim of this case report is to describe a patient with acute lymphoblastic leukemia (ALL) who developed bilateral serous retinal detachments and unilateral optic disc swelling. METHODS: A 23-year-old woman with ALL presented to the ophthalmology clinic with bilateral subacute visual loss. RESULTS: Ophthalmologic examination revealed bilateral serous retinal detachments and unilateral optic disc swelling. Magnetic resonance imaging for differential diagnosis was inconclusive; however, cerebrospinal fluid sampling demonstrated leukemic involvement of the central nervous system...
July 15, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28709702/clinical-and-morphologic-characteristics-of-mek-inhibitor-associated-retinopathy-differences-from-central-serous-chorioretinopathy
#2
Jasmine H Francis, Larissa A Habib, David H Abramson, Lawrence A Yannuzzi, Murk Heinemann, Mrinal M Gounder, Rachel N Grisham, Michael A Postow, Alexander N Shoushtari, Ping Chi, Neil H Segal, Rona Yaeger, Alan L Ho, Paul B Chapman, Federica Catalanotti
PURPOSE: To investigate the clinical and morphologic characteristics of serous retinal disturbances in patients taking mitogen-activated protein kinase kinase (MEK) inhibitors. PARTICIPANTS: A total of 313 fluid foci in 50 eyes of 25 patients receiving MEK inhibitors for treatment of their metastatic cancer, who had evidence of serous retinal detachments confirmed by optical coherence tomography (OCT). DESIGN: Single-center, retrospective cohort study...
July 12, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28682907/evaluation-of-sysmex-xn-1000-hematology-analyzer-for-cell-count-and-screening-of-malignant-cells-of-serous-cavity-effusion
#3
Weiyi Xu, Qian Yu, Lixia Xie, Baode Chen, Ling Zhang
Over the years, with the advancement in hematology analyzer technology, the use of fluid analysis method has seen a drastic increase in clinical examinations. Cell counting and classification in independent body fluid analysis method are conducted by semiconductor laser flow cytometry and nucleic acid fluorescence staining techniques. This study is to evaluate the efficacy of Sysmex XN-1000 hematology analyzer in cell counting and to screen malignant cells with serous cavity effusion. Specimens (N = 206) with serous cavity effusion from our hospital were included in this study...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28681573/monomorphic-epitheliotropic-intestinal-t-cell-lymphoma-in-pleural-effusion-a-case-report
#4
F Antoniadou, A Dimitrakopoulou, P M Voutsinas, K Vrettou, I Vlahadami, M Voulgarelis, P Korkolopoulou, N Kafasi, P Mikou
Dissemination of lymphomas in serous effusions is quite common. Cytology aims to contribute in the clinical management of haematologic patients, providing an accurate and rapid diagnosis. Ancillary techniques such as immunocytochemistry and flow cytometry are essential to classify the lymphoma entity. Comprehensive awareness of the clinical picture and previous histologic documentation are essential for a lymphomatous effusion diagnosis. We report an unusual case of monomorphic epitheliotropic intestinal T-cell lymphoma, formerly known as enteropathy associated T-cell lymphoma (EATL) type II, spreading in the pleural cavity...
July 5, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28680734/hydroxyapatite-bone-cement-application-for-the-reconstruction-of-retrosigmoid-craniectomy-in-the-treatment-of-cranial-nerves-disorders
#5
Nouman Aldahak, Derrick Dupre, Mohamed Ragaee, Sebastien Froelich, Jack Wilberger, Khaled M Aziz
BACKGROUND: Retromastoid craniectomy (RSC) is a cardinal surgical approach used to access the posterior fossa. Hydroxyapetite bone cement (HBC) is frequently employed for cranioplasty in efforts to prevent cerebrospinal fluid (CSF) leak, whilst maintaining low complication rates and good cosmetic satisfaction. The authors aim to determine the safety and effectiveness of HBC for reconstruction RSC used for treatment of various cranial nerves disorders. METHODS: The authors conducted a retrospective one-center two surgeons review of 113 patients who underwent RSC filled with HBC for the treatment of cranial nerve disorders...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28674835/photodynamic-therapy-in-chronic-central-serous-chorioretinopathy-with-subretinal-fluid-outside-the-fovea
#6
Elon H C van Dijk, Greet Dijkman, Camiel J F Boon
PURPOSE: To assess the efficacy of photodynamic therapy (PDT) in patients with chronic central serous chorioretinopathy (cCSC), in whom subretinal fluid (SRF) was solely present outside the foveal area. METHODS: In this retrospective study, 16 eyes of 15 cCSC patients who received half-dose PDT because of notable subjective visual complaints due to the presence of extrafoveal SRF, were included. An ophthalmic examination was performed before treatment, including Early Treatment Diabetic Retinopathy Study best-corrected visual acuity measurement, applanation tonometry, slit-lamp examination, and indirect ophthalmoscopy, followed by multimodal imaging, including fundus photography, fundus autofluorescence, spectral-domain optical coherence tomography (OCT), enhanced-depth imaging OCT of the choroid, fluorescein angiography, and indocyanine green angiography...
July 3, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28673727/central-serous-chorioretinopathy-and-glucocorticoids-an-update-on-evidence-for-association
#7
REVIEW
Benjamin P Nicholson, Elizabeth Atchison, Amrou Ali Idris, Sophie J Bakri
Central serous chorioretinopathy (CSC) is a common idiopathic retinal disease characterized by central vision loss from serous detachment of the neurosensory retina, serous pigment epithelial detachments, and leakage of fluid through the retinal pigment epithelium into the sub-retinal space. The concept of an association between exogenous glucocorticoid use and CSC is widely accepted among ophthalmologists. Here we review the evidence for and against such an association. This evidence includes two large, case-control studies that found strong associations, and a smaller, population-based study that found no association...
June 30, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28653813/eplerenone-for-chronic-central-serous-chorioretinopathy-a-randomized-controlled-prospective-study
#8
Roy Schwartz, Zohar Habot-Wilner, Michael R Martinez, Amir Nutman, Dafna Goldenberg, Shai Cohen, Shiri Shulman, Hanan Guzner-Gur, Anat Loewenstein, Michaella Goldstein
PURPOSE: To evaluate the efficacy and safety of eplerenone for chronic nonresolving central serous chorioretinopathy (CSC). METHODS: Prospective, double-blind, randomized placebo-controlled study. Nineteen eyes of 17 patients with persistent subretinal fluid (SRF) due to CSC were enrolled and randomized to receive eplerenone 50 mg/day or placebo for 3 months, followed by a 3-month follow-up. The main outcome measure was change in SRF from baseline to 3 months of treatment...
June 27, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/28649123/extraovarian-primary-peritoneal-carcinomatosis-a-case-report
#9
Gregory Nicolas, Tony Kfoury, Hassan Fawaz, Mahdi Issa
BACKGROUND Extraovarian primary peritoneal carcinoma (EOPPC) is a rare malignant epithelial tumor with an age-adjusted incidence rate of 6.78 per million, which arises from the peritoneal lining with minimal or no ovarian involvement. EOPPC is a diagnosis of exclusion with the absence of other identifiable primary sites and after surgical assessment and consideration of the histological report to evaluate the extent of ovarian invasion. CASE REPORT A 66-year-old woman complained of mild postprandial epigastric pain...
June 26, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28633941/pancreatic-cyst-fluid-vascular-endothelial-growth-factor-a-and-carcinoembryonic-antigen-a-highly-accurate-test-for-the-diagnosis-of-serous-cystic-neoplasm
#10
Rosalie A Carr, Michele T Yip-Schneider, Scott Dolejs, Bradley A Hancock, Huangbing Wu, Milan Radovich, C Max Schmidt
BACKGROUND: Accurate differentiation of pancreatic cystic lesions is important for pancreatic cancer early detection and prevention as well as avoidance of unnecessary surgical intervention. Serous cystic neoplasms (SCN) have no malignant potential, but may mimic premalignant mucinous cystic lesions: mucinous cystic neoplasm (MCN) and intraductal papillary mucinous neoplasm (IPMN). We recently identified vascular endothelial growth factor (VEGF)-A as a novel pancreatic fluid biomarker for SCN...
May 18, 2017: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/28607529/ev-associated-mmp9-in-high-grade-serous-ovarian-cancer-is-preferentially-localized-to-annexin-v-binding-evs
#11
Agnes T Reiner, Sisareuth Tan, Christiane Agreiter, Katharina Auer, Anna Bachmayr-Heyda, Stefanie Aust, Nina Pecha, Mattias Mandorfer, Dietmar Pils, Alain R Brisson, Robert Zeillinger, Sai Kiang Lim
High-grade serous ovarian cancer (HGSOC) is the most aggressive type of ovarian cancer and is responsible for most deaths caused by gynecological cancers. Numerous candidate biomarkers were identified for this disease in the last decades, but most were not sensitive or specific enough for clinical applications. Hence, new biomarkers for HGSOC are urgently required. This study aimed to identify new markers by isolating different extracellular vesicle (EV) types from the ascites of ovarian cancer patients according to their affinities for lipid-binding proteins and analyzing their protein cargo...
2017: Disease Markers
https://www.readbyqxmd.com/read/28606265/-the-fundus-manifestations-and-sd-oct-findings-of-patients-with-acute-vogt-koyanagi-harada-disease
#12
B Li, J J Ye, M F Zhang, D H Li
Objective: To conclude the characteristics of fundus appearance and spectral domain optical coherence tomography(SD-OCT) findings of patients with acute Vogt-Koyanagi-Harada (VKH) disease. Methods: The clinical data of 17 patients (34 eyes) diagnosed of acute VKH in Peking Union Medical College Hospital from Jan. 2012 to Dec. 2014 were studied retrospectively.Examinations included visual acuity, slit lamp, fundus, color fundus pictures, FFA and SD-OCT. Results: Eight men and 9 women were enrolled with mean age of (40...
June 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28588687/retroperitoneal-fibrosis-and-constrictive-pericarditis-igg4-related-diseases-a-case-report
#13
Brankica Terzic, Marijan Spasic, Predrag Djuric, Vladimir Vasiljevic, Slavica Radjen, Mirjana Mijuskovic
Retroperitoneal fibrosis (RPF) is a rare disease characterized by infiltration of inflammatory cells and deposition of thickened fibrous tissues. The present study presents the case of a 53-year-old patient treated for generalized weakness and fatigue for 1 year prior to hospitalization. A cardiac ultrasound revealed pericardial effusion that required pericardiocentesis, during which 1,400 ml serous fluid with the characteristics of an exudate was aspirated. A pericardiectomy was performed due to persistent effusion and histological examination indicated pericardial fibrosis...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28559772/classifying-hydroceles-of-the-pelvis-and-groin-an-overview-of-etiology-secondary-complications-evaluation-and-management
#14
REVIEW
Gautam Dagur, Jason Gandhi, Yiji Suh, Steven Weissbart, Yefim R Sheynkin, Noel L Smith, Gargi Joshi, Sardar Ali Khan
INTRODUCTION: A hydrocele is defined as the pathological buildup of serous fluid in the pelvis and groin due to various etiologies such as diseases or trauma. It has distinct clinical manifestations, particularly discomfort and psychosocial distress. Understanding the anatomy, embryology, and physiology associated with hydrocele formation is crucial to understand its onset and progression. MATERIALS AND METHODS: A MEDLINE(®) search was conducted using keywords for the relevant classification of hydrocele and its etiology, complications, sexual barriers, evaluation, and management...
April 2017: Current Urology
https://www.readbyqxmd.com/read/28520626/multimodal-imaging-of-acute-exudative-polymorphous-vitelliform-maculopathy-with-optical-coherence-tomography-angiography-and-adaptive-optics-scanning-laser-ophthalmoscopy
#15
Dimitra Skondra, Peter L Nesper, Amani A Fawzi
PURPOSE: To report a case of acute exudative polymorphous vitelliform maculopathy including the findings of optical coherence tomography angiography and adaptive optics scanning laser ophthalmoscopy. METHODS: Findings on clinical examination, color fundus photography, spectral-domain optical coherence tomography, infrared reflectance, autofluorescence, optical coherence tomography angiography, and adaptive optics scanning laser ophthalmoscopy. RESULTS: A 54-year-old white man with no significant medical history and history of smoking presented with bilateral multiple serous and vitelliform detachments consistent with acute exudative polymorphous vitelliform maculopathy...
May 16, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/28514814/-possibilities-and-limitations-of-oct-angiography-in-patients-with-central-serous-chorioretinopathy
#16
B Cakir, M Reich, S J Lang, A Bühler, A Stahl, D Böhringer, H Agostini, C Lange
Purpose Central serous chorioretinopathy (CSC) is a commonly acquired maculopathy characterized by the accumulation of subretinal fluid at the posterior pole. This study aims to analyze optical coherence tomography angiography (OCTA) findings in patients with acute and chronic CSC and to compare them to conventional imaging methods. Methods A series of 43 consecutive eyes of 29 patients diagnosed with CSC and 18 eyes of 9 healthy control subjects were included in this retrospective study. The OCTA images were assessed and compared to conventional fluorescence (FAG) and indocyanine green angiography (ICG)...
May 17, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/28511236/long-term-outcomes-after-endoscopic-ultrasound-guided-ablation-of-pancreatic-cysts
#17
Jun-Ho Choi, Dong Wan Seo, Tae Jun Song, Do Hyun Park, Sang Soo Lee, Sung Koo Lee, Myung-Hwan Kim
Background and study aims The aim of this study was to investigate the long-term outcomes after endoscopic ultrasound (EUS)-guided pancreatic cyst ablation. Patients and methods In a single-center, prospective study, 164 patients with pancreatic cysts underwent EUS-guided cyst ablation using ethanol with paclitaxel. The inclusion criteria were as follows: unilocular or oligolocular cysts; clinically indeterminate cysts that required EUS fine-needle aspiration; and/or cysts that grew during the observation period...
May 16, 2017: Endoscopy
https://www.readbyqxmd.com/read/28508379/-retinal-pigment-epithelial-detachment-in-hyperviscosity-syndrome
#18
V C Müller, N Mihailovic, C R Clemens, F Alten, N Eter
We present a case of a 57-year-old woman who reported bilateral visual impairment since 2 weeks. She had a medical history of congenital, cyanotic heart failure. Funduscopic examination revealed serous retinal detachment on the left side, central subneurosensory detachment on the right side, retinal vessel tortuosity and multiple retinal haemorrhages in the periphery. As blood analysis showed a distinct increase in haemoglobin and haematocrit, hyperviscosity syndrome was suspected to have caused bilateral serous retinal detachment...
May 15, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28489693/dysfunctional-autonomic-regulation-of-the-choroid-in-central-serous-chorioretinopathy
#19
C Nathaniel Roybal, Elisabeth Sledz, Yasser Elshatory, Li Zhang, David R P Almeida, Eric K Chin, Brice Critser, Michael D Abramoff, Stephen R Russell
PURPOSE: To study the effect of changing perfusion pressures on retinal and choroidal structure in central serous chorioretinopathy (CSC). METHODS: This prospective observational case series included seven healthy volunteers (14 eyes) and seven patients (14 eyes) with CSC. Each patient underwent spectral domain optical coherence tomography with enhanced depth imaging in the upright (sitting) and supine positions. Image segmentation focused on central macular thickness, subretinal fluid, total macular volume, choroidal thickness, and choriocapillaris thickness...
May 9, 2017: Retina
https://www.readbyqxmd.com/read/28474320/large-hemobezoar-causing-acute-small-bowel-obstruction-after-roux-en-y-gastric-bypass-laparoscopic-management
#20
Emanuele Soricelli, Enrico Facchiano, Giovanni Quartararo, Benedetta Beltrame, Luca Leuratti, Marcello Lucchese
The present video shows the laparoscopic management of an acute small bowel obstruction (ASBO) after a Roux-en-Y Gastric Bypass (RYGBP), due to the development of an intraluminal hemobezoar involving the jejuno-jejunostomy (j-j). On the first postoperative day (POD), the patient presented persistent abdominal pain, sense of fullness, nausea, and vomiting with traces of blood. The abdominal tube drained a small amount of serous fluid, while blood tests revealed a mild leukocytosis and a slight decrease of the hemoglobin...
May 4, 2017: Obesity Surgery
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