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https://www.readbyqxmd.com/read/28804801/pancreatic-enzyme-supplementation-after-gastrectomy-for-gastric-cancer-a-randomized-controlled-trial
#1
Marco Catarci, Manuele Berlanda, Giovanni Battista Grassi, Francesco Masedu, Stefano Guadagni
BACKGROUND: Gastrectomy for gastric cancer is a significant cause of secondary exocrine pancreatic insufficiency. Pancreatic enzyme replacement therapy may influence nutritional status and quality of life after gastrectomy, but the pertinent clinical research to date remains controversial. A randomized controlled trial to test this hypothesis was carried out. METHODS: After gastrectomy, 43 patients with gastric cancer were randomly assigned to a normal diet (Normal-d; n = 21) or to a pancreatic enzyme supplementation diet (PES-d; n = 22) and were followed up during a 12-month period, assessing nutritional status and quality of life through body mass index (BMI), instant nutritional assessment (INA) class status, serum pre-albumin (SPA) values, and GastroiIntestinal Quality of Life Index (GIQLI)...
August 14, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28798306/hyperspectral-imaging-for-predicting-the-internal-quality-of-kiwifruits-based-on-variable-selection-algorithms-and-chemometric-models
#2
Hongyan Zhu, Bingquan Chu, Yangyang Fan, Xiaoya Tao, Wenxin Yin, Yong He
We investigated the feasibility and potentiality of determining firmness, soluble solids content (SSC), and pH in kiwifruits using hyperspectral imaging, combined with variable selection methods and calibration models. The images were acquired by a push-broom hyperspectral reflectance imaging system covering two spectral ranges. Weighted regression coefficients (BW), successive projections algorithm (SPA) and genetic algorithm-partial least square (GAPLS) were compared and evaluated for the selection of effective wavelengths...
August 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28798229/role-of-technetium-99m-methylene-diphosphonate-spect-ct-in-the-detection-of-sacroiliitis-in-patients-with-spondyloarthropathy-comparison-with-clinical-markers-and-mri
#3
Rahul V Parghane, Baljinder Singh, Aman Sharma, Harmandeep Singh, Paramjit Singh, Anish Bhattacharya
Rationale: To evaluate the role of (99m)Tc-MDP SPECT/CT for the detection of sacroiliitis in spondyloarthopathies (SpA) and comparison with clinical markers and MRI. Methods: A total of 155 diagnosed patients (83M : 72 F; mean age 35.80±12.40 years; range 18-60 years ) with SpA as per the European Spondyloarthropathy Study Group criteria (ESSG) criteria were prospectively included All the patients were subjected to clinical evaluation (using BASDAI scoring), ESR, CRP levels, planar (99m)Tc MDP bone scintigraphy, hybrid SPECT/CT and MRI of the pelvic region...
August 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28792263/implementing-and-evaluating-a-community-based-inter-institutional-interprofessional-education-pilot-programme
#4
Chante Stubbs, Mavis N Schorn, Jacinta P Leavell, Elena Wong Espiritu, Gerald Davis, Chad K Gentry, Elisa Friedman, Traci Patton, Ali Graham, Ron Crowder, Consuelo H Wilkins
Many health professions programmes have begun integrating interprofessional learning into their curricula; however, community-based interprofessional education (IPE) initiatives are relatively scarce. The Meharry-Vanderbilt Alliance IPE Faculty Collaborative, comprised of faculty from five institutions, developed a community-based IPE programme that allowed students to engage in meaningful interprofessional activities while exposing them to social determinants of health. Thirty students from ten professions were divided into six teams and paired with three community organisations...
August 9, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28791026/decrease-of-markers-related-to-bone-erosion-in-serum-of-patients-with-musculoskeletal-disorders-after-serial-low-dose-radon-spa-therapy
#5
Aljona Cucu, Kateryna Shreder, Daniela Kraft, Paul Friedrich Rühle, Gerhart Klein, Gerhard Thiel, Benjamin Frey, Udo S Gaipl, Claudia Fournier
Musculoskeletal disorders (MSDs) are the most frequent cause of disability in Europe. Reduced mobility and quality of life of the patients are often associated with pain due to chronic inflammation. The inflammatory process, accompanied by a destruction of the cartilage and bone tissue, is discussed as a result of (A) the infiltration of immune cells into the joints, (B) an altered homeostasis of the joint cavity (synovium) with a critical role of bone remodeling cells, and (C) release of inflammatory factors including adipokines in the arthritic joint...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28790806/perceptions-of-patients-with-rheumatic-diseases-on-the-impact-on-daily-life-and-satisfaction-with-their-medications-rheu-life-a-survey-to-patients-treated-with-subcutaneous-biological-products
#6
Carlos M González, Loreto Carmona, Javier de Toro, Enrique Batlle-Gualda, Antonio I Torralba, María J Arteaga, Luis Cea-Calvo
OBJECTIVE: The aim of this study was to explore perceptions of patients with rheumatic diseases treated with subcutaneous (SC) biological drugs on the impact on daily life and satisfaction with current therapy, including preferred attributes. METHODS: A survey was developed ad hoc by four rheumatologists and three patients, including Likert questions on the impact of disease and treatment on daily life and preferred attributes of treatment. Rheumatologists from 50 participating centers were instructed to handout the survey to 20 consecutive patients with rheumatoid arthritis (RA), axial spondyloarthritis (ax-SpA), or psoriatic arthritis (PsA) receiving SC biological drugs...
2017: Patient Preference and Adherence
https://www.readbyqxmd.com/read/28783429/characterization-of-livestock-associated-methicillin-resistant-staphylococcus-aureus-cc398-and-mecc-positive-cc130-from-zoo-animals-in-the-united-kingdom
#7
Alessio Bortolami, Ranieri Verin, Julian Chantrey, Michela Corrò, Ian Ashpole, Javier Lopez, Dorina Timofte
Little is known about the characteristics and diseases associated with methicillin-resistant Staphylococcus aureus (MRSA) in nondomestic animals. Four presumptive MRSA isolates, obtained from clinical (n = 3) and surveillance specimens (n = 1) from dwarf (Helogale parvula) and yellow mongooses (Cynictis penicillata) from a United Kingdom zoo, were analyzed by PCR for detection of mecA and mecC-mediated methicillin resistance, and virulence genes. Isolates were genotyped by multilocus sequence typing (MLST) and staphylococcal cassette chromosome mec (SCCmec) and spa sequence typing...
August 7, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28783314/deciphering-the-role-of-sulfonated-unit-in-heparin-mimicking-polymer-to-promote-neural-differentiation-of-escs
#8
Jiehua Lei, Yuqi Yuan, Zhonglin Lyu, Mengmeng Wang, Qi Liu, Hongwei Wang, Lin Yuan, Hong Chen
Glycosaminoglycans (GAGs), especially heparin and heparan sulfate (HS) hold great potential for inducing the neural differentiation of embryonic stem cells (ESCs) and have brought new hope for the treatment of neurological diseases. However, the disadvantages of natural heparin/HS, such as difficulty in isolating with a sufficient amount, highly heterogeneous in structure, the risk of immune responses, have limited their further therapeutic applications. Thus, there is a great demand for stable, controllable and well-defined synthetic alternatives of heparin/HS with more effective biological functions...
August 7, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28782651/emergence-of-dalbavancin-non-susceptible-vancomycin-intermediate-staphylococcus-aureus-visa-after-treatment-of-mrsa-central-line-associated-bloodstream-infection-with-a-dalbavancin-and-vancomycin-containing-regimen
#9
Brian J Werth, Rupali Jain, Andrew Hahn, Lisa Cummings, Tatiana Weaver, Adam Waalkes, Dhruba Sengupta, Stephen J Salipante, Robert M Rakita, Susan M Butler-Wu
OBJECTIVES: Dalbavancin is a long-acting lipoglycopeptide with activity against Gram-positives, including methicillin-resistant Staphylococcus aureus(MRSA). The potential for lipoglycopeptides, with half-lives greater than one-week, to select for resistance is unknown. Here we explore a case of MRSA central line-associated blood stream infection in which dalbavancin and vancomycin non-susceptibility emerged in a urine isolate collected after the patient was treated with vancomycin and dalbavancin sequentially...
August 3, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28780098/prevalence-and-characterization-of-methicillin-resistant-staphylococcus-aureus-carrying-meca-or-mecc-and-methicillin-susceptible-staphylococcus-aureus-in-dairy-sheep-farms-in-central-italy
#10
G Giacinti, V Carfora, A Caprioli, D Sagrafoli, N Marri, G Giangolini, R Amoruso, M Iurescia, F Stravino, S Dottarelli, F Feltrin, A Franco, S Amatiste, A Battisti
Between January and May 2012, a total of 286 bulk tank milk samples from dairy sheep farms located in central Italy were tested for the presence of Staphylococcus aureus. One hundred fifty-three samples were positive for S. aureus (53.5%), with an average count of 2.53 log cfu/mL. A total of 679 S. aureus colonies were screened for methicillin resistance by the cefoxitin disk diffusion test, and 104 selected cefoxitin-susceptible isolates were also tested for their susceptibility to other antimicrobials representative of the most relevant classes active against Staphylococcus spp...
August 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28776771/efficacious-holidays-the-therapeutic-dimensions-of-pleasure-and-discipline-in-czech-respiratory-spas
#11
Susanna Trnka
As evidence-based medicine has increasingly become the standard for assessing the efficacy of health care, the Czech Republic finds itself in a dilemma, with centuries of sanatorium-style spa treatments resisting easy categorization. Despite some critics' contentions that spas are "pointless holidays" and reductions in government funding of health spas, in 2014 Czech courts affirmed every Czech citizen's right to spa treatments if their health status merits it. Drawing on research in two children's respiratory spas, this article considers the experiences of patients aged two-15 and their accompanying parents or guardians (mainly mothers) to suggest that in addition to the range of therapeutic procedures highlighted within spa cures, more amorphous aspects-such as pleasure and discipline-may be just as central to spas' successes...
August 4, 2017: Medical Anthropology Quarterly
https://www.readbyqxmd.com/read/28776360/biomarkers-imaging-and-disease-activity-indices-in-patients-with-early-axial-spondyloarthritis-the-italian-arm-of-the-spondyloarthritis-caught-early-space-study
#12
M Lorenzin, A Ortolan, S Vio, M Favero, F Oliviero, M Zaninotto, C Cosma, C Lacognata, L Punzi, R Ramonda
The study aimed to evaluate biomarkers facilitating early diagnosis of axial spondyloarthritis (axSpA) and correlations between them and disease activity parameters and imaging indexes. Patients with low back pain (LBP) (≥3 months, ≤2 years, onset ≤45 years) participating in the Italian arm of the SpondyloArthritis-Caught-Early SPACE study underwent a physical examination, questionnaires, laboratory tests, X-rays and MRI of the spine and sacroiliac joints (SIJ). An expert rheumatologist formulated axSpA diagnosis in accordance with Assessment of SpondyloArthritis International Society (ASAS) criteria...
August 3, 2017: Reumatismo
https://www.readbyqxmd.com/read/28771160/staphylococcus-aureus-isolated-from-wastewater-treatment-plants-in-tunisia-occurrence-of-human-and-animal-associated-lineages
#13
Meriam Ben Said, Mohamed Salah Abbassi, Paula Gómez, Laura Ruiz-Ripa, Senda Sghaier, Chourouk Ibrahim, Carmen Torres, Abdennaceur Hassen
The objective was to characterize Staphylococcus aureus isolated from two wastewater treatment plants (WWTPs) located in Tunis City (Tunisia), during the period 2014-2015. Genetic lineages, antibiotic resistance mechanisms and virulence factors were determined for the recovered isolates. S. aureus isolates were recovered from 12 of the 62 wastewater samples tested (19.35%), and one isolate/sample was characterized, all of them being methicillin-susceptible (MSSA). Six spa types (t587, t674, t224, t127, t701 and t1534) were found among the 12 isolates, and the spa-t587, associated with the new sequence type ST3245, was the most predominant one (7 isolates)...
August 2017: Journal of Water and Health
https://www.readbyqxmd.com/read/28771156/radioactivity-and-hydrochemical-properties-of-certain-thermal-turkish-spa-waters
#14
Muazzez Çelik Karakaya, Mahmut Doğru, Necati Karakaya, Fatih Kuluöztürk, Mahmut Tahir Nalbantçılar
The study aims to determine the radioactivity levels of thermal waters which have been used seasonally or permanently in spas for therapeutic intentions. Samples were collected from spas in different regions of Turkey. Some radionuclides ((40)K, (232)Th, (226)Ra, (137)Cs), gross alpha (GA) and gross beta (GB) activities, and physical and some chemical parameters were measured. Gamma radiation measurements for (226)Ra, (232)Th and (40)K radionuclides were performed by using a high purity germanium (HPGe) detector...
August 2017: Journal of Water and Health
https://www.readbyqxmd.com/read/28769113/spondyloarthritis-reinforcing-treat-to-target-for-spa
#15
Sarah Onuora
No abstract text is available yet for this article.
August 3, 2017: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/28768510/educational-needs-in-patients-with-spondyloarthritis-in-sweden-a-mixed-methods-study
#16
Emma Haglund, Ann Bremander, Stefan Bergman, Ingrid Larsson
BACKGROUND: There is a demand for a flexible and individually tailored patient education to meet patients' specific needs and priorities, but this area has seldom been studied in patients with spondyloarthritis (SpA), a family of inflammatory rheumatic diseases. The aim of the present study was to identify needs and priorities in patient education in patients with SpA. A second aim was to investigate patients' experiences and preferences of receiving patient education. METHODS: Data collection included a questionnaire survey with the Educational Needs Assessment Tool (ENAT) and interviews, using a mixed-methods design...
August 2, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28767630/predictive-findings-of-the-presence-of-stooping-in-patients-with-lumbar-degenerative-kyphosis-by-upright-whole-spine-lateral-radiography
#17
Seung Min Son, Jong Ki Shin, Tae Sik Goh, Kuen Tak Suh, Jung Sub Lee
STUDY DESIGN: Retrospective study. OBJECTIVE: To identify the relationships between radiological findings and the presence of stooping in lumbar degenerative kyphosis (LDK). SUMMARY OF BACKGROUND DATA: Many studies have addressed fixed sagittal imbalances and surgical treatments. However, information regarding the relationship between radiological findings and stooping in LDK is sparse. METHODS: The study included 73 patients with LDK and 44 with normal lumbar lordosis...
August 1, 2017: Spine
https://www.readbyqxmd.com/read/28764693/the-relationship-between-demographic-and-disease-related-variables-and-health-related-quality-of-life-in-patients-with-axial-spondyloarthritis
#18
Gudrun Rohde, Kari Hansen Berg, Anne Prøven, Glenn Haugeberg
BACKGROUND: Axial spondyloarthritis (ax-SpA) is a chronic inflammatory disease of the spine causing pain, stiffness, loss in physical function, and fatigue. Therefore, the physical and psychological burden of having this chronic disease can reduce the quality of life. We aimed to explore the relationship between demographic- and disease-related variables and health-related quality of life (HRQoL) in patients with ax-SpA. METHODS: Demographic- and disease-related, HRQoL-related and treatment data were collected...
August 1, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28762060/a-2-year-observational-study-on-treatment-targets-in-psoriatic-arthritis-patients-treated-with-tnf-inhibitors
#19
Maria Sole Chimenti, Paola Triggianese, Paola Conigliaro, Marco Tonelli, Gianfranco Gigliucci, Lucia Novelli, Miriam Teoli, Roberto Perricone
The aim of this study was to evaluate clinical remission and MDA in PsA patients who started TNF-inhibitors (TNFi) treatment with a 2-year follow-up. Concomitant therapies as well as comorbidities were assessed. Level of concordance of clinimetric indices and the potential predictive factors of remission/MDA were also evaluated. Clinical and laboratory evaluations were prospectively performed in PsA patients at baseline (T0) and after 22 (T22), 54 (T54), and 102 (T102) weeks of treatment. Disease activity and disability were assessed using DAS28, CPDAI, DAPSA, MDA, and HAQ-SpA...
July 31, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28761820/immuno-biosensor-for-detection-of-cd20-positive-cells-using-surface-plasmon-resonance
#20
REVIEW
Dariush Shanehbandi, Jafar Majidi, Tohid Kazemi, Behzad Baradaran, Leili Aghebati-Maleki, Farzaneh Fathi, Jafar Ezzati Nazhad Dolatabadi
Purpose: Surface plasmon resonance (SPR) sensing confers a real-time assessment of molecular interactions between biomolecules and their ligands. This approach is highly sensitive and reproducible and could be employed to confirm the successful binding of drugs to cell surface targets. The specific affinity of monoclonal antibodies (MAb) for their target antigens is being utilized for development of immuno-sensors and therapeutic agents. CD20 is a surface protein of B lymphocytes which has been widely employed for immuno-targeting of B-cell related disorders...
June 2017: Advanced Pharmaceutical Bulletin
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