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https://www.readbyqxmd.com/read/29905652/dynamic-sodium-imaging-at-ultra-high-field-reveals-progression-in-a-preclinical-migraine-model
#1
Nastaren Abad, Jens T Rosenberg, David C Hike, Michael G Harrington, Samuel C Grant
Under the hypothesis that increased extracellular sodium induces sustained neuronal excitability with the onset and progression of migraine, this study evaluates dynamic in vivo Na fluxes in the brain of a preclinical rodent analogue of migraine. Ultra-high field Na MRI at 21.1 T has demonstrated potential to quantify sodium concentrations with good spatial and temporal resolution following the onset of central sensitization. Sprague-Dawley male rats with implanted intraperitoneal (IP) lines were studied by MRI before and after an in situ injection of 10 mg/kg of nitroglycerin (NTG) versus vehicle and saline controls...
June 12, 2018: Pain
https://www.readbyqxmd.com/read/29904858/brain-mri-in-patients-affected-by-migraine-with-aura-is-there-any-cortical-lesion
#2
Katia Khouri Chalouhi, Silvia Squarza, Anna Pisani Mainini, Paola Di Fiore, Maurizio Cariati, Fabio Frediani, Carla Uggetti
No abstract text is available yet for this article.
June 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29904830/migraine-and-cerebrovascular-disease-still-a-dangerous-connection
#3
Elio Clemente Agostoni, Marco Longoni
Migraine is a common type of headache in young adults, with an estimated prevalence of 4% before puberty and as high as 25% in women by their mid to late 30s. About one third of migraineurs experience transient neurological symptoms known as auras, which characterize a variant known as migraine with aura. Many evidences have shown an increased risk of vascular events in patients affected by migraine, particularly among women and among migraine patients with aura. Potential underlying mechanisms include endothelial dysfunction, hypercoagulability, platelet aggregation, vasospasm, cardiovascular risk factors, paradoxical embolism, spreading depolarization, shared genetic risk, use of non-steroidal anti-inflammatory drugs, and immobilization...
June 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29900326/data-of-ascending-cortical-vein-occlusion-induced-spreading-depression
#4
Buket Dönmez-Demir, Muge Yemisci, Turgay Dalkara
The data presented in this article are related to the research article entitled "Microembolism of single cortical arterioles can induce spreading depression and ischemic injury; a potential trigger for migraine and related MRI lesions" (Donmez-Demir et al., 2018) [1]. This article presents data showing that thrombosis of a small ascending cortical vein (25 µm) in the mouse may also trigger spreading depression as does penetrating arteriole occlusion, although less frequently (22% vs. 100%).
June 2018: Data in Brief
https://www.readbyqxmd.com/read/29899730/brain-correlates-of-single-trial-visual-evoked-potentials-in-migraine-more-than-meets-the-eye
#5
Marco Lisicki, Kevin D'Ostilio, Gianluca Coppola, Alain Maertens de Noordhout, Vincenzo Parisi, Jean Schoenen, Delphine Magis
Background: Using conventional visual evoked potentials (VEPs), migraine patients were found to be hyperresponsive to visual stimulus. Considering that a significant portion of neuronal activity is lost for analysis in the averaging process of conventional VEPs, in this study we investigated visual evoked responses of migraine patients and healthy volunteers using a different approach: single trial analysis. This method permits to preserve all stimulus-induced neuronal activations, whether they are synchronized or not...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29883214/advances-in-migraine-neuroimaging-and-clinical-utility-from-the-mri-to-the-bedside
#6
Antonio Russo, Marcello Silvestro, Alessandro Tessitore, Gioacchino Tedeschi
In current migraine clinical practice, no specific diagnostic investigations are available and therefore the diagnosis is an eminently clinical process where instrumental examinations may have a part to exclude possible causes of secondary headaches. While migraine clinical phenotype has been widely characterized, migraine pathophysiology has still a gap that might be partly bridged by structural and functional neuroimaging investigations. Areas Covered: This article aims to review the recent advances in functional neuroimaging, the consequent progress in the knowledge of migraine pathophysiology and their putative application and impact in the clinical setting...
June 8, 2018: Expert Review of Neurotherapeutics
https://www.readbyqxmd.com/read/29881904/migraine-with-extensive-skin-markings-a-case-report
#7
Sabrina Berdouk, Sobia Khan
BACKGROUND: Migraines are a commonly seen complaint in the emergency department, but migraines with extensive skin markings have rarely been reported and so the cause is still unknown. CASE PRESENTATION: We report a 28-year-old Pakistani male complaining of recurrent migraines that are now associated with skin markings that appear on his forehead and last for a few days and then disappear on their own. A diagnosis of migraines with cutaneous markings was made. An MRI was done on the patient and showed normal results...
June 7, 2018: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29876641/olfactory-bulbus-volume-and-olfactory-sulcus-depth-in-migraine-patients-an-mri-evaluation
#8
Adil Doğan, Nuray Bayar Muluk, Mehmet Hamdi Şahan, Neşe Asal, Mikail Inal, Ufuk Ergün
OBJECTIVES: To compare the measurements of olfactory bulb volume and olfactory sulcus depth in patients with migraine and a control group. METHODS: The study included the cranial MRI (1.5 T) images of 200 adults diagnosed with migraine and a control group of 100 subjects without migraine. The control group mainly consisted of the patients with non-migraneous headache. The measurements were obtained from coronal T2-weighted images for standard olfactory bulb (OB) volume and olfactory sulcus (OS) depth...
June 6, 2018: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29870626/-childhood-sporadic-type-of-hemiplegic-migraine-with-arteria-cerebri-media-hypoperfusion
#9
Csaba Nagy, Gábor Bajzik, Andrea Skobrák, Eszter Csorba, Anikó Lajtai, Gábor Balogh, Ferenc Nagy, Zsolt Vajda
Hemiplegic migraine is a rare subtype of migraine that is associated with reversible motor weakness in the aura phase. This is an uncommon form of migraine usually starting in childhood. The purpose of this case report is to highlight the differential diagnostic difficulty of the first attack. We describe a case, where the fluctuating unilateral motor weakness and aphasia suggested that the patient had ischaemic stroke. Nevertheless the brain MRI and MR angiography, the measured 5-hydroxyindole acetic acid (5-HIAA) concentration changes and the spontaneously improving clinical status proved the diagnosis of hemiplegic migraine...
September 30, 2017: Ideggyógyászati Szemle
https://www.readbyqxmd.com/read/29866668/case-of-primary-sjogren-s-syndrome-preceded-by-dystonia
#10
Kerime Ararat, Idanis Berrios, Anas Hannoun, Carolina Ionete
There are only six cases in literature that describe development of dystonia with Sjogren's syndrome (SS). We describe a case of a 43-year-old woman who presented with symptoms including movement disorder, sensory neurogenic bladder, sensory loss and neuropathic pain, migraine like headaches, musculoskeletal pain, Raynaud's phenomenon and dysautonomia. Symptoms started in 2000, with weakness that progressed to dystonia in 2003. Diagnostic work-up was inconclusive with negative inflammatory serologies, cerebrospinal fluid and MRI for many years...
June 4, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29848110/volume-and-shape-of-subcortical-grey-matter-structures-related-to-headache-a-cross-sectional-population-based-imaging-study-in-the-nord-tr%C3%A3-ndelag-health-study
#11
Andreas Kattem Husøy, Carl Pintzka, Live Eikenes, Asta K Håberg, Knut Hagen, Mattias Linde, Lars Jacob Stovner
Background The relationship between subcortical nuclei and headache is unclear. Most previous studies were conducted in small clinical migraine samples. In the present population-based MRI study, we hypothesized that headache sufferers exhibit reduced volume and deformation of the nucleus accumbens compared to non-sufferers. In addition, volume and deformation of the amygdala, caudate, hippocampus, pallidum, putamen and thalamus were examined. Methods In all, 1006 participants (50-66 years) from the third Nord-Trøndelag Health Survey, were randomly selected to undergo a brain MRI at 1...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29844925/decompression-for-botulinum-toxin-exacerbated-cervical-myeloradiculopathy-in-the-setting-of-congenital-stenosis-and-arnold-chiari-i-malformation
#12
Abhinav Mohan, Eric Chang
Introduction: We present a case describing the management of a woman with severe, functionally limiting cervical myeloradiculopathy in the setting of congenital cervical canal stenosis and Arnold-Chiari I malformation. Case presentation: The subject is a 57-year-old woman with prior anterior cervical discectomy and fusion who presented with left-sided neck pain associated with radiculopathy, migraine, gait incoordination, and cervical dystonia. Cervical stenosis and Chiari malformation were confirmed using MRI...
2018: Spinal Cord Series and Cases
https://www.readbyqxmd.com/read/29809228/migraine-improvement-correlates-with-posterior-cingulate-cortical-thickness-reduction
#13
Vanise C G Amaral, Gustavo Tukamoto, Tadeu Kubo, Ronir Raggio Luiz, Emerson Gasparetto, Maurice B Vincent
Objective The main goal of this study was to correlate migraine improvement, after prophylactic therapy, with cortical thickness changes. Methods Cortical thickness maps were obtained with magnetic resonance imaging (MRI) from 19 patients with migraine before (first scan) and after (second scan) prophylactic treatment, and these were compared with controls using the FreeSurfer MRI tool. Cortical changes were correlated with the headache index (HI). Results Anincrease incortical thickness was found in the right cuneus and precuneus, somatosensory and superior parietal cortices in both patient scans, compared with the controls...
March 2018: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/29801894/migraine-as-possible-red-flag-of-pfo-presence-in-suspected-demyelinating-disease
#14
E Signoriello, M Cirillo, G Puoti, G Signoriello, A Negro, E Koci, M A B Melone, A Rapacciuolo, G Maresca, G Lus
OBJECTIVES: To investigate a possible association between isolated white matter lesions suggestive of demyelinating disease in magnetic resonance imaging (MRI) and patent foramen ovale (PFO) evidence in migraine patients, with or without aura. MATERIALS: 31 migraine patients, 28 females and 3 males, with MRI evidence of white matter lesions suggestive of demyelinating disease according to the Barkhof Criteria. All patients underwent further diagnostics including lumbar puncture, autoimmunity panel and cardiological evaluation to detect the presence of PFO...
July 15, 2018: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/29799347/detection-of-microbleeds-associated-with-sentinel-headache-using-mri-quantitative-susceptibility-mapping-pilot-study
#15
Daichi Nakagawa, Kohsuke Kudo, Olatilewa Awe, Mario Zanaty, Yasunori Nagahama, Cameron Cushing, Vincent Magnotta, Minako Hayakawa, Lauren Allan, Jeremy Greenlee, Issam A Awad, Timothy Carroll, James Torner, Madhavan L Raghavan, David M Hasan
OBJECT Sentinel headaches (SHs) associated with cerebral aneurysms (CAs) could be due to microbleeds, which are considered a sign that an aneurysm is unstable. Despite the prognostic importance of these microbleeds, they remain difficult to detect using routine imaging studies. The objective of this pilot study is to detect microbleeds associated with SH using a magnetic resonance imaging (MRI) quantitative susceptibility mapping (QSM) sequence and then evaluate the morphological characteristics of unstable aneurysms with microbleeds...
May 25, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29777478/the-relationship-with-restless-legs-syndrome-fibromyalgia-and-depressive-symptoms-in-migraine-patients
#16
Zehra Akdag Uzun, Semiha Kurt, Hatice Karaer Unaldi
OBJECTIVE: In this study, we aimed to investigate restless legs syndrome, depression, frequency of fibromyalgia and possible causes of its frequencies, and the relationships among these synergies and migraine's prodrome, aura, pain, and postdrome symptoms in patients with migraine. SUBJECTS AND METHODS: The study group included 200 patients previously or recently diagnosed with definite migraine and according to International Headache Society criteria and 200 healthy volunteers...
May 18, 2018: Neurological Sciences
https://www.readbyqxmd.com/read/29668636/spinal-dural-arteriovenous-fistula-presenting-with-subarachnoid-hemorrhage-a-case-report
#17
Jingzhe Han, Duanhua Cao, Hongmei Wang, Ye Ji, Zhilei Kang, Jianguo Zhu
RATIONALE: Subarachnoid hemorrhage (SAH) is a common and serious disease and one of the most important differential diagnoses in the emergency department. PATIENT CONCERNS: A 39-year-old female patient with a 12 years' history of migraine, presented with a sudden headache combined with motor aphasia. Physical examination suggested probable positive neck resistance. SAH was confirmed by magnetic resonance imaging. In addition, spinal digital subtraction angiography and spinal vascular computed tomography angiography indicated spinal arteriovenous malformation (SAVM)...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29623825/functional-neuroimaging-biomarkers-in-migraine-diagnostic-prognostic-and-therapeutic-implications
#18
Antonio Russo, Marcello Silvestro, Alessandro Tessitore, Gioacchino Tedeschi
INTRODUCTION: in current migraine clinical practice conventional neuroimaging examinations are often sought to exclude possible causes of secondary headaches or migraine-associated disorders. Contrariwise, although advanced magnetic resonance imaging (MRI) has improved tremendously our understanding of human brain processes in migraine patients, to the state of the art they have not superseded the conventional neuroimaging techniques in the migraine clinical setting. METHODS: a comprehensive review was conducted of PubMed citations by entering the key word "marker" AND/OR "biomarker" combined with "migraine" AND/OR "headache...
April 5, 2018: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/29607917/-cadasil-with-cysteine-sparing-notch3-mutation-manifesting-as-dissociated-progression-between-cognitive-impairment-and-brain-image-findings-in-3-years-a-case-report
#19
Keisuke Tachiyama, Yuji Shiga, Yutaka Shimoe, Ikuko Mizuta, Toshiki Mizuno, Masaru Kuriyama
A 55-year-old man with no history of stroke or migraine presented to the clinic with cognitive impairment and depression that had been experiencing for two years. Neurological examination showed bilateral pyramidal signs, and impairments in cognition and attention. Brain MRI revealed multiple lacunar lesions and microbleeds in the deep cerebral white matter, subcortical regions, and brainstem, as well as diffuse white matter hyperintensities without anterior temporal pole involvement. Cerebral single-photon emission computed tomography (SPECT) revealed bilateral hypoperfusion in the basal ganglia...
April 25, 2018: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/29592973/cortical-laminar-necrosis-in-a-case-of-migrainous-cerebral-infarction
#20
Vikram Khardenavis, Davala Krishna Karthik, Sharvari Kulkarni, Anirudda Deshpande
We report a 27-year-old woman, a known case of classical migraine headache, on oral contraceptive pills. She had a severe episode of migraine with visual aura attack, which continued late into the night. The next early morning, her headache persisted and she developed abrupt onset of dysarthria, right hemiparaesthesias. She attributed symptoms to her long-standing headache problem, and hence did not seek medical help for the next two weeks. The symptoms persisted despite her headache subsiding over the next 24 hours...
March 28, 2018: BMJ Case Reports
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