Shota Kosuge, Yuri Masaoka, Hideyo Kasai, Motoyasu Honma, Kouzou Murakami, Nobuyuki Yoshii, Keiko Watanabe, Takaaki Naito, Miku Kosuge, Misa Matsui, Daiki Shoji, Syunsuke Sakakura, Hidetomo Murakami, Masahiko Izumizaki
This study aimed to explore the relationship between gray matter volume changes and various clinical parameters in patients with migraine, focusing on symptom severity, quality of life, and states of depression and anxiety. Using a case-control design, we examined 33 patients with migraine, with or without aura, and 27 age-matched healthy subjects. We used magnetic resonance imaging to assess the volumes of 140 bilateral brain regions. Clinical evaluations included the Migraine Disability Assessment, the Migraine Specific Quality of Life Questionnaire, the Center for Epidemiologic Studies Depression scale, Spielberger's State and Trait Anxiety scales, and the Japanese version of the Montreal Cognitive Assessment...
2024: PloS One