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https://www.readbyqxmd.com/read/29235771/schedules-of-controlled-substances-placement-of-mt-45-into-schedule-i-final-order
#1
(no author information available yet)
With the issuance of this final order, the Administrator of the Drug Enforcement Administration places the substance MT-45 (Systematic IUPAC Name: 1-cyclohexyl-4-(1,2-diphenylethyl)piperazine), including its salts, isomers, and salts of isomers into schedule I of the Controlled Substances Act. This scheduling action is pursuant to the Controlled Substances Act and is required in order for the United States to discharge its obligations under the Single Convention on Narcotic Drugs, 1961. This action imposes the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances on persons who handle (manufacture, distribute, import, export, engage in research or conduct instructional activities with, or possess), or propose to handle, MT-45...
December 13, 2017: Federal Register
https://www.readbyqxmd.com/read/29199914/rethinking-the-relationship-between-socioeconomic-status-and-health-challenging-how-socioeconomic-status-is-currently-used-in-health-inequality-research
#2
Thierry Gagné, Adrian E Ghenadenik
AIMS: The Scandinavian Journal of Public Health recently reiterated the importance of addressing social justice and health inequalities in its new editorial policy announcement. One of the related challenges highlighted in that issue was the limited use of sociological theories able to inform the complexity linking the resources and mechanisms captured by the concept of socioeconomic status. This debate article argues that part of the problem lies in the often unchallenged reliance on a generic conceptualization and operationalization of socioeconomic status...
December 1, 2017: Scandinavian Journal of Public Health
https://www.readbyqxmd.com/read/29172557/expanding-the-early-and-late-starter-model-of-criminal-justice-involvement-for-forensic-mental-health-clients
#3
Anne G Crocker, Michael S Martin, Marichelle C Leclair, Tonia L Nicholls, Michael C Seto
The early and late starter model provides one of the most enduring frameworks for understanding the developmental course and severity of violence and criminality among individuals with severe mental illness. We expanded the model to account for differences in the age of onset of criminal behavior and added a group with no prior contact with the justice or mental health systems. We sampled 1,800 men and women found Not Criminally Responsible on account of Mental Disorder in 3 Canadian provinces. Using a retrospective file-based study, we explored differences in criminal, health, demographic, and social functioning characteristics, processing through the forensic psychiatric system and recidivism outcomes of 5 groups...
November 27, 2017: Law and Human Behavior
https://www.readbyqxmd.com/read/29170833/inclusion-of-assistive-technologies-in-a-basic-package-of-essential-healthcare-service
#4
Fiachra O'Brolcháin, Bert Gordijn
This paper outlines the potential and necessity of the development of assistive technologies (AT) for people with intellectual disabilities (IDs). We analyse a policy recommendation designed to determine the contents of a basic health package supplied by the state, known as the Dunning Funnel. We contend that the Dunning Funnel is a useful methodology, but is weakened by a potentially relativistic understanding of "necessity" in relation to the requirements of people with IDs (i.e., community standards will determine whether AT are necessary)...
November 23, 2017: HEC Forum: An Interdisciplinary Journal on Hospitals' Ethical and Legal Issues
https://www.readbyqxmd.com/read/29144594/on-the-origin-of-obesity-identifying-the-biological-environmental-and-cultural-drivers-of-genetic-risk-among-human-populations
#5
REVIEW
A Qasim, M Turcotte, R J de Souza, M C Samaan, D Champredon, J Dushoff, J R Speakman, D Meyre
Genetic predisposition to obesity presents a paradox: how do genetic variants with a detrimental impact on human health persist through evolutionary time? Numerous hypotheses, such as the thrifty genotype hypothesis, attempt to explain this phenomenon yet fail to provide a justification for the modern obesity epidemic. In this critical review, we appraise existing theories explaining the evolutionary origins of obesity and explore novel biological and sociocultural agents of evolutionary change to help explain the modern-day distribution of obesity-predisposing variants...
November 16, 2017: Obesity Reviews: An Official Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29124683/the-21st-century-cures-act-implications-for-the-reduction-of-racial-health-disparities-in-the-us-criminal-justice-system-a-public-health-approach
#6
Donna M Cole, Dawna Marie Thomas, Kelsi Field, Amelia Wool, Taryn Lipiner, Natalie Massenberg, Barbara J Guthrie
Past drug epidemics have disproportionately criminalized drug addiction among African Americans, leading to disparate health outcomes, increased rates of HIV/AIDS, and mass incarceration. Conversely, the current opioid addiction crisis in the USA focuses primarily on white communities and is being addressed as a public health problem. The 21st Century Cures Act has the potential to reduce racial health disparities in the criminal justice system through the Act's public health approach to addiction and mental health issues...
November 9, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29124449/the-evolution-of-public-health-ethics-frameworks-systematic-review-of-moral-values-and-norms-in-public-health-policy
#7
REVIEW
Mahmoud Abbasi, Reza Majdzadeh, Alireza Zali, Abbas Karimi, Forouzan Akrami
Given the evolution of the public health (PH) and the changes from the phenomenon of globalization, this area has encountered new ethical challenges. In order to find a coherent approach to address ethical issues in PH policy, this study aimed to identify the evolution of public health ethics (PHE) frameworks and the main moral values and norms in PH practice and policy. According to the research questions, a systematic search of the literature, in English, with no time limit was performed using the main keywords in databases Web of Science (ISI) and PubMed...
November 9, 2017: Medicine, Health Care, and Philosophy
https://www.readbyqxmd.com/read/29110543/police-legitimacy-and-compliance-with-the-law-among-chinese-youth
#8
Siyu Liu, Jianhong Liu
The process-based model of policing garnered considerable support in the discourse on police legitimacy. However, findings are largely based on Western contexts, and little attention has been paid to the model advanced by Tyler that police legitimacy helps promote compliance. Using a high school sample ( N = 711) from China, we follow Tankebe's operationalization and examine the role of legitimacy in youth support for the police and whether legitimacy helps predict compliance with the law. Findings indicate that procedural justice and shared values are strong predictors of youth support to the police, and this support positively predicts compliance with the law...
November 1, 2017: International Journal of Offender Therapy and Comparative Criminology
https://www.readbyqxmd.com/read/29098846/schedules-of-controlled-substances-temporary-placement-of-fub%C3%A2-amb-into-schedule-i-temporary-amendment-temporary-scheduling-order
#9
(no author information available yet)
The Administrator of the Drug Enforcement Administration is issuing this temporary scheduling order to schedule the synthetic cannabinoid, methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate [FUB-AMB, MMB-FUBINACA, AMB-FUBINACA], and its optical, positional, and geometric isomers, salts, and salts of isomers into schedule I. This action is based on a finding by the Administrator that the placement of this synthetic cannabinoid into schedule I of the Controlled Substances Act is necessary to avoid an imminent hazard to the public safety...
November 3, 2017: Federal Register
https://www.readbyqxmd.com/read/29098204/sexual-orientation-gender-and-environmental-injustice-unequal-carcinogenic-air-pollution-risks-in-greater-houston
#10
Timothy W Collins, Sara E Grineski, Danielle X Morales
Disparate residential hazard exposures based on disadvantaged gender status (e.g., among female-headed households) have been documented in the distributive environmental justice literature, yet no published studies have examined whether disproportionate environmental risks exist based on minority sexual orientation. To address this gap, we use data from the US Census, American Community Survey and the Environmental Protection Agency at the 2010 census tract level to examine the spatial relationships between same-sex partner households and cumulative cancer risk from exposure to hazardous air pollutants (HAPs) emitted by all ambient emission sources in Greater Houston (Texas)...
2017: Annals of the American Association of Geographers
https://www.readbyqxmd.com/read/29095111/distributive-justice-and-regenerative-medicine
#11
John Gardner
Many countries have identified regenerative medicine as a strategic priority, and have thus launched a range of initiatives to facilitate innovation in the field. This perspective paper argues that several initiatives involve resource distributions that could impinge on widely accepted egalitarian notions of fairness and justice that underpin current healthcare systems. Specifically, this paper focuses on five initiatives, and argues that these initiatives reflect a largely unacknowledged utilitarian perspective on distributive justice...
November 2, 2017: Regenerative Medicine
https://www.readbyqxmd.com/read/29093697/children-s-inequity-aversion-in-procedural-justice-context-a-comparison-of-advantageous-and-disadvantageous-inequity
#12
Xiaoju Qiu, Jing Yu, Tingyu Li, Nanhua Cheng, Liqi Zhu
There are two forms of unfairness widely studied in resource allocation settings: disadvantageous inequity (DI) in which one receives less than the partner and advantageous inequity (AI) in which one receives more than the other. We investigated children's aversion to AI and DI in a procedural justice context. Children of 4-, 6-, and 8- years old were asked to spin a wheel (procedure) to decide how to allocate two different rewards with others. In each condition, they chose between a fair procedure providing equal chances for the two parties to get the bigger reward, and an unfair procedure (either a disadvantageous procedure in the DI condition, or an advantageous procedure in the AI condition)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29091366/schedules-of-controlled-substances-temporary-placement-of-ortho-fluorofentanyl-tetrahydrofuranyl-fentanyl-and-methoxyacetyl-fentanyl-into-schedule-i-temporary-amendment-temporary-scheduling-order
#13
(no author information available yet)
The Administrator of the Drug Enforcement Administration is issuing this temporary scheduling order to schedule the synthetic opioids, N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)propionamide (ortho-fluorofentanyl or 2-fluorofentanyl), N-(1-phenethylpiperidin-4-yl)-N-phenyltetrahydrofuran-2-carboxamide (tetrahydrofuranyl fentanyl), and 2-methoxy-N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide (methoxyacetyl fentanyl), into Schedule I. This action is based on a finding by the Administrator that the placement of ortho-fluorofentanyl, tetrahydrofuranyl fentanyl, and methoxyacetyl fentanyl into Schedule I of the Controlled Substances Act is necessary to avoid an imminent hazard to the public safety...
October 26, 2017: Federal Register
https://www.readbyqxmd.com/read/29048385/disease-and-health-inequalities-attributable-to-air-pollutant-exposure-in-detroit-michigan
#14
Sheena E Martenies, Chad W Milando, Guy O Williams, Stuart A Batterman
The environmental burden of disease is the mortality and morbidity attributable to exposures of air pollution and other stressors. The inequality metrics used in cumulative impact and environmental justice studies can be incorporated into environmental burden studies to better understand the health disparities of ambient air pollutant exposures. This study examines the diseases and health disparities attributable to air pollutants for the Detroit urban area. We apportion this burden to various groups of emission sources and pollutants, and show how the burden is distributed among demographic and socioeconomic subgroups...
October 19, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29035496/schedules-of-controlled-substances-placement-of-ab-chminaca-abpinaca-and-thj-2201-into-schedule-i-final-rule
#15
(no author information available yet)
With the issuance of this final rule, the Drug Enforcement Administration places N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide (AB-CHMINACA), N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole-3-carboxamide (AB-PINACA), and [1-(5-fluoropentyl)-1H-indazol-3-yl](naphthalen-1-yl)methanone (THJ-2201), including their salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible, into schedule I of the Controlled Substances Act...
October 16, 2017: Federal Register
https://www.readbyqxmd.com/read/29033634/sudden-unexpected-death-in-epilepsy-a-retrospective-autopsy-study-of-112-epileptic-patients
#16
İpek Esen Melez, Murat Nihat Arslan, Deniz Oğuzhan Melez, Ahmet Necati Şanli, Sermet Koç
INTRODUCTION: Sudden unexpected deaths comprise the most important and worthy investigation case profiles in both neurology and forensic medicine. Epilepsy, which is one of the neuropathological causes of sudden unexpected deaths, is an important disorder having mysterious aspects. The aim of this study is to make common the points of view between neurology and forensic medicine experts and to discuss the features of the findings together with the related clinical hypotheses, leading to the differential diagnosis of sudden unexpected death in epilepsy (SUDEP) by presenting autopsy findings and available medical data of patients who had a prior diagnosis of epilepsy...
September 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/29028466/is-acute-care-oriented-research-ethical-in-resource-limited-settings
#17
Anwar D Jackson, Harold W Neighbors
In this case scenario, a medical student, Jenny, is conducting congenital heart disease research in a resource-limited setting faced with water insecurity. She has concerns about how ethical it is for her to conduct advanced clinical research in a region with more basic health needs. The first commentary argues that advanced clinical research in resource-limited settings follows the ethical principle of beneficence and interactional justice but violates the principle of distributive justice. The second commentary questions whether beneficence is enough, since the Belmont Report states that beneficence is the obligation to simultaneously reduce harm and increase benefit...
October 1, 2017: AMA Journal of Ethics
https://www.readbyqxmd.com/read/28991888/commonly-prescribed-antiretroviral-therapy-regimens-and-incidence-of-aids-defining-neurological-conditions
#18
Ellen C Caniglia, Andrew Phillips, Kholoud Porter, Caroline A Sabin, Alan Winston, Roger Logan, John Gill, Marie-Anne Vandenhende, Diana Barger, Sara Lodi, Santiago Moreno, José Ramón Arribas, Antonio Pacheco, Sandra W Cardoso, George Chrysos, Charalabos Gogos, Sophie Abgrall, Dominique Costagliola, Laurence Meyer, Remonie Seng, Ard van Sighem, Peter Reiss, Roberto Muga, Santiago Pérez Hoyos, Dominique Braun, Christoph Hauser, Pilar Barrufet, Maria Leyes, Janet Tate, Amy Justice, Miguel A Hernán
BACKGROUND: The differential effects of commonly prescribed combined antiretroviral therapy (cART) regimens on AIDS-defining neurological conditions (neuroAIDS) remain unknown. SETTING: Prospective cohort studies of HIV-positive individuals from Europe and the Americas included in the HIV-CAUSAL Collaboration. METHODS: Individuals who initiated a first-line cART regimen in 2004 or later containing a nucleoside reverse transcriptase inhibitor (NRTI) backbone and either atazanavir, lopinavir, darunavir, or efavirenz were followed from cART initiation until death, lost to follow-up, pregnancy, the cohort-specific administrative end of follow-up, or the event of interest, whichever occurred earliest...
October 4, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28990740/schedules-of-controlled-substances-removal-of-naldemedine-from-control-final-rule
#19
(no author information available yet)
With the issuance of this final rule, the Drug Enforcement Administration removes the substance naldemedine (4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-N-(2-(3-phenyl-1,2,4-oxadiazol-5-yl)propan-2-yl)-2,3,4,4a,5,7a-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide) including its salts from the schedules of the Controlled Substances Act. Prior to the effective date of this rule, naldemedine was a schedule II controlled substance because it can be derived from opium alkaloids. This action removes the regulatory controls and administrative, civil, and criminal sanctions applicable to controlled substances, including those specific to schedule II controlled substances, on persons who handle (manufacture, distribute, reverse distribute, dispense, conduct research, import, export, or conduct chemical analysis) or propose to handle naldemedine...
September 29, 2017: Federal Register
https://www.readbyqxmd.com/read/28976822/accelerating-regenerative-medicine-the-japanese-experiment-in-ethics-and-regulation
#20
Tamra Lysaght
In 2014, the Japanese National Diet introduced new laws aimed at promoting the clinical translation of stem cells and regenerative medicine. The basic action of these laws is to allow the early introduction of regenerative medicine products into the Japanese market through an accelerated approval process, while providing patients with access to certain types of stem cell and cell-based therapies in the context of private clinical practice. While this framework appears to offer enormous opportunities for the translation of stem cell science, it raises ethical challenges that have not yet been fully explored...
September 2017: Regenerative Medicine
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