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Traumatic stress

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https://www.readbyqxmd.com/read/28742078/longitudinal-changes-in-glucocorticoid-receptor-exon-1f-methylation-and-psychopathology-after-military-deployment
#1
R R Schür, M P Boks, B P F Rutten, N P Daskalakis, L de Nijs, M van Zuiden, A Kavelaars, C J Heijnen, M Joëls, R S Kahn, E Geuze, E Vermetten, C H Vinkers
Several cross-sectional studies have demonstrated the relevance of DNA methylation of the glucocorticoid receptor exon 1F region (GR-1F) for trauma-related psychopathology. We conducted a longitudinal study to examine GR-1F methylation changes over time in relation to trauma exposure and the development of post-deployment psychopathology. GR-1F methylation (52 loci) was quantified using pyrosequencing in whole blood of 92 military men 1 month before and 6 months after a 4-month deployment period to Afghanistan...
July 25, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28741845/self-regulation-shift-theory-a-dynamic-systems-approach-to-traumatic-stress
#2
Charles C Benight, Kotaro Shoji, Douglas L Delahanty
Self-regulation shift theory (SRST) is a threshold theory explaining self-regulation following trauma that utilizes nonlinear dynamics to capture systemic shifts in trauma adaptation. Cusp catastrophe modeling tests nonlinear changes in an outcome (e.g., posttraumatic distress) based on an identified bifurcation factor under specific conditions (i.e., asymmetry variables). We evaluated two cusp models in a motor vehicle accident (MVA) database and then confirmed findings within a similar dataset. Based on SRST, we tested coping self-efficacy (CSE) as the bifurcation factor and a set of asymmetry controlling variables...
July 25, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28741810/gender-differences-in-machine-learning-models-of-trauma-and-suicidal-ideation-in-veterans-of-the-iraq-and-afghanistan-wars
#3
Jaimie L Gradus, Matthew W King, Isaac Galatzer-Levy, Amy E Street
Suicide rates among recent veterans have led to interest in risk identification. Evidence of gender-and trauma-specific predictors of suicidal ideation necessitates the use of advanced computational methods capable of elucidating these important and complex associations. In this study, we used machine learning to examine gender-specific associations between predeployment and military factors, traumatic deployment experiences, and psychopathology and suicidal ideation (SI) in a national sample of veterans deployed during the Iraq and Afghanistan conflicts (n = 2,244)...
July 25, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28741670/intensive-cognitive-therapy-for-post-traumatic-stress-disorder-in-routine-clinical-practice-a-matched-comparison-audit
#4
Hannah Murray, Sharif El-Leithy, Jo Billings
OBJECTIVES: Intensive cognitive therapy for post-traumatic stress disorder (PTSD) has been shown to be as effective as weekly treatment in controlled trials. In this study, outcome data comparing standard and intensive treatments delivered in routine clinical practice were analysed. METHODS: A consecutive case series of intensive treatment cases were compared to matched control cases who had completed weekly treatment. RESULTS: Both groups showed significant improvements on PTSD and depression measures...
July 25, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28741031/inhibition-of-serotonin-transporters-disrupts-the-enhancement-of-fear-memory-extinction-by-3-4-methylenedioxymethamphetamine-mdma
#5
Matthew B Young, Seth D Norrholm, Lara M Khoury, Tanja Jovanovic, Sheila A M Rauch, Collin M Reiff, Boadie W Dunlop, Barbara O Rothbaum, Leonard L Howell
RATIONALE: 3,4-Methylenedioxymethamphetamine (MDMA) persistently improves symptoms of post-traumatic stress disorder (PTSD) when combined with psychotherapy. Studies in rodents suggest that these effects can be attributed to enhancement of fear memory extinction. Therefore, MDMA may improve the effects of exposure-based therapy for PTSD, particularly in treatment-resistant patients. However, given MDMA's broad pharmacological profile, further investigation is warranted before moving to a complex clinical population...
July 24, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28740632/psychological-effects-on-patient-s-relatives-regarding-their-presence-during-resuscitation
#6
Hassan Soleimanpour, Jafar Sadegh Tabrizi, Asghar Jafari Rouhi, Samad Ej Golzari, Ata Mahmoodpoor, Robab Mehdizadeh Esfanjani, Maryam Soleimanpour
Introduction: Presence of family and patients' relatives throughout resuscitation procedure is one of the most challenging concerns. Methods: In an interventional (quasi-experimental) study that was conducted during a 6 months period, the patients' relatives were randomly divided into two groups of intervention (the relatives who were eager to be present throughout the resuscitation procedure- under the family protection protocol, all of the procedure steps were explained to the relatives by an expert nurse who was not involved in the resuscitation procedure and control group (those who were not invited routinely to be present throughout the resuscitation procedure...
2017: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/28740430/a-systematic-literature-review-exploring-the-prevalence-of-post-traumatic-stress-disorder-and-the-role-played-by-stress-and-traumatic-stress-in-breast-cancer-diagnosis-and-trajectory
#7
REVIEW
Paola Arnaboldi, Silvia Riva, Chiara Crico, Gabriella Pravettoni
Stress has been extensively studied as a psychosomatic factor associated with breast cancer. This study aims to review the prevalence of post-traumatic stress disorder (PTSD), its associated risk factors, the role of predicting factors for its early diagnosis/prevention, the implications for co-treatment, and the potential links by which stress could impact cancer risk, by closely examining the literature on breast cancer survivors. The authors systematically reviewed studies published from 2002 to 2016 pertaining to PTSD, breast cancer and PTSD, and breast cancer and stress...
2017: Breast Cancer: Targets and Therapy
https://www.readbyqxmd.com/read/28739293/psychological-recovery-after-intensive-care-outcomes-of-a-long-term-quasi-experimental-study-of-structured-nurse-led-follow-up
#8
Rannveig J Jónasdóttir, Helga Jónsdóttir, Berglind Gudmundsdottir, Gisli H Sigurdsson
OBJECTIVES: To compare psychological recovery of patients receiving structured nurse-led follow-up and patients receiving usual care after intensive care discharge. DESIGN: Quasi-experimental study. SETTING: Single centre, university hospital, mixed intensive care patient population. MAIN OUTCOME MEASURES: Symptoms of post-traumatic stress disorder, anxiety and depression measured three and four times over 12 months after intensive care discharge...
July 21, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28739068/management-of-emergence-delirium-in-adult-ptsd-patients-recommendations-for-practice
#9
Donnamarie Lovestrand, Steven Lovestrand, Denise M Beaumont, Jonathan G Yost
Emergence delirium is a known phenomenon which occurs after general anesthesia in approximately 5% of the general population. However, individuals who have been diagnosed with post-traumatic stress disorder may present with symptoms refractory to conventional methods of reorientation. In the past several years, literature has begun to address the problem, but no standardized guidelines exist at present. The authors synthesize the available literature, combining data with evidence-driven principles from multiple disciplines, to submit an initial set of guidelines until research either supports or disproves these recommendations...
August 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28738687/critical-incident-stress-debriefing-after-adverse-patient-safety-events
#10
Reema Harrison, Albert Wu
Adverse events (AEs) are common, estimated to occur in around 10% internationally. Although preventable harm can be minimized, when AEs occur it is important that they be managed appropriately. AEs can be traumatic not only for patients, their friends, and relatives, but also for the involved clinicians, who have been referred to as "second victims" in a growing body of international research. Despite the frequency with which AEs occur, organizational mechanisms for supporting staff in these circumstances are not routinely embedded in healthcare settings...
May 2017: American Journal of Managed Care
https://www.readbyqxmd.com/read/28738210/neural-activity-and-emotional-processing-following-military-deployment-effects-of-mild-traumatic-brain-injury-and-posttraumatic-stress-disorder
#11
Daniel V Zuj, Kim L Felmingham, Matthew A Palmer, Ellie Lawrence-Wood, Miranda Van Hooff, Andrew J Lawrence, Richard A Bryant, Alexander C McFarlane
Posttraumatic Stress Disorder (PTSD) and mild traumatic brain injury (mTBI) are common comorbidities during military deployment that affect emotional brain processing, yet few studies have examined the independent effects of mTBI and PTSD. The purpose of this study was to examine distinct differences in neural responses to emotional faces in mTBI and PTSD. Twenty-one soldiers reporting high PTSD symptoms were compared to 21 soldiers with low symptoms, and 16 soldiers who reported mTBI-consistent injury and symptoms were compared with 16 soldiers who did not sustain an mTBI...
July 21, 2017: Brain and Cognition
https://www.readbyqxmd.com/read/28738029/confronting-compassion-fatigue-assessment-and-intervention-in-inpatient-oncology%C3%A2
#12
Lisa M Zajac, Katherine J Moran, Carla J Groh
BACKGROUND: A notable variation among patient satisfaction scores with nursing care was identified. Contributing factors were examined and revealed significant negative correlations between the unit death rate and surviving patients' satisfaction scores. Compassion fatigue (CF) was hypothesized to be a major contributing factor.
. OBJECTIVES: The objective was to address CF in RNs and oncology care associates (assistive personnel) by developing an intervention to provide bereavement support to staff after patient deaths...
August 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28737954/an-app-a-day-keeps-the-doctor-away-guided-education-and-training-via-smartphones-in-subthreshold-post-traumatic-stress-disorder
#13
Michael J Roy, Michelle E Costanzo, Krista B Highland, Cara Olsen, Denece Clayborne, Wendy Law
Post traumatic stress disorder (PTSD) symptoms are common in military service members (SMs), but stigma can impede treatment initiation. Smartphone applications (apps) are available anywhere, anytime, with the potential to both mitigate the impact of stigma and reduce PTSD symptom severity. We provided 144 SMs or family members, with subthreshold PTSD symptoms (PTSD Checklist [PCL] scores of 28-49), with apps promoting psychoeducation, social engagement, and relaxation and randomized them to 6 weeks of resilience enhancement (brief cognitive-behavioral session, followed by daily text messages directing app use) or a control group (daily text messages of inspirational quotes)...
July 24, 2017: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/28736792/double-injected-human-stem-cells-enhance-rehabilitation-in-tbi-mice-via-modulation-of-survival-and-inflammation
#14
Chul Kim, Ji-Min Park, TaeHo Kong, Seungmin Lee, Ki-Weon Seo, Yuri Choi, Young Sook Song, Jisook Moon
Traumatic brain injury (TBI), a complicated form of brain damage, is a major cause of mortality in adults. Following mechanical and structural primary insults, a battery of secondary insults, including neurotransmitter-mediated cytotoxicity, dysregulation of calcium and macromolecule homeostasis, and increased oxidative stress, exacerbate brain injury and functional deficits. Although stem cell therapy is considered to be an alternative treatment for brain injuries, such as TBI and stroke, many obstacles remain...
July 24, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28736465/network-indicators-of-the-social-ecology-of-adolescents-in-relative-and-non-relative-foster-households
#15
Jennifer Blakeslee, Brianne H Kothari, Bowen McBeath, Paul Sorenson, Lew Bank
Though the presence, composition, and quality of social relationships-particularly as found in family networks-has an important influence on adolescent well-being, little is known about the social ecology of youth in foster care. This study examined the social networks of foster youth participating in a large RCT of an intervention for siblings in foster care. Youth reported on the people they lived with and the relatives they were in contact with, which provided indicators of network size, composition, and relationship quality...
February 2017: Children and Youth Services Review
https://www.readbyqxmd.com/read/28735779/a-systematic-review-of-variables-associated-with-sleep-paralysis
#16
REVIEW
Dan Denis, Christopher C French, Alice M Gregory
Sleep paralysis is a relatively common but under-researched phenomenon. While the causes are unknown, a number of studies have investigated potential risk factors. In this article, we conducted a systematic review on the available literature regarding variables associated with both the frequency and intensity of sleep paralysis episodes. A total of 42 studies met the inclusion criteria. For each study, sample size, study site, sex and age of participants, sleep paralysis measure, and results of analyses looking at the relationship(s) between sleep paralysis and associated variable(s) were extracted...
June 8, 2017: Sleep Medicine Reviews
https://www.readbyqxmd.com/read/28734152/trajectories-of-alcohol-use-in-the-uk-military-and-associations-with-mental-health
#17
L Goodwin, S Norton, N T Fear, M Jones, L Hull, S Wessely, R J Rona
INTRODUCTION: There are higher levels of alcohol misuse in the military compared to the general population. Yet there is a dearth of research in military populations on the longitudinal patterns of alcohol use. This study aims to identify group trajectories of alcohol consumption in the UK military and to identify associations with childhood adversity, deployment history and mental disorder. METHODS: Data on weekly alcohol consumption across an eight year period and three phases of a UK military cohort study (n=667) were examined using growth mixture modelling...
July 12, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28731844/outcome-by-gender-in-the-veterans-health-administration-motivating-overweight-obese-veterans-everywhere-weight-management-program
#18
Bryan C Batch, Karen Goldstein, William S Yancy, Linda L Sanders, Susanne Danus, Steven C Grambow, Hayden B Bosworth
BACKGROUND: Few evaluations of the Veterans Health Administration Motivating Overweight/Obese Veterans Everywhere (MOVE!) weight management program have assessed 6-month weight change or factors associated with weight change by gender. MATERIALS AND METHODS: Analysis of administrative data from a national sample of veterans in the VA MOVE! PROGRAM: HASH(0x5356be8) RESULTS: A total of 62,882 participants were included, 14...
July 21, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/28731565/a-narrative-synthesis-of-women-s-out-of-body-experiences-during-childbirth
#19
Lynda Bateman, Catriona Jones, Julie Jomeen
INTRODUCTION: Some women have a dissociated, out-of-body experience (OBE) during childbirth, which may be described as seeing the body from above or floating above the body. This review examines this phenomenon using narratives from women who have experienced intrapartum OBEs. METHODS: A narrative synthesis of qualitative research was employed to systematically synthesize OBE narratives from existing studies. Strict inclusion and exclusion criteria were applied...
July 21, 2017: Journal of Midwifery & Women's Health
https://www.readbyqxmd.com/read/28729949/modeling-the-effect-of-blunt-impact-on-mitochondrial-function-in-cartilage-implications-for-development-of-osteoarthritis
#20
Georgi I Kapitanov, Bruce P Ayati, James A Martin
OBJECTIVE: Osteoarthritis (OA) is a disease characterized by degeneration of joint cartilage. It is associated with pain and disability and is the result of either age and activity related joint wear or an injury. Non-invasive treatment options are scarce and prevention and early intervention methods are practically non-existent. The modeling effort presented in this article is constructed based on an emerging biological hypothesis-post-impact oxidative stress leads to cartilage cell apoptosis and hence the degeneration observed with the disease...
2017: PeerJ
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