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Cyanoacrylate and mesh

Toshinari Kawasaki, Kazumichi Yoshida, Takayuki Kikuchi, Akira Ishii, Yasushi Takagi, Susumu Miyamoto
BACKGROUND: Concerning traumatic aneurysms, those of the superficial temporal artery (STA) have been frequently reported in the literature, whereas those of the occipital artery (OA) are extremely rare. CASE DESCRIPTION: A 30-year-old man had been followed at another hospital for meningoencephalocele associated with his congenital occipital bone defect. He was admitted to our hospital with a chief complaint of neck swelling and pain during a football game. CT and MRI showed a hematoma in his right neck along with the meningoencephalocele...
October 11, 2016: World Neurosurgery
Mar Fernández-Gutiérrez, Marta Rodriguez-Mancheño, Bárbara Pérez-Köhler, Gemma Pascual, Juan Manuel Bellón, Julio San Román
The article deals with a comparative analysis of the parameters of the polymerization in physiological conditions of three commercially available alkyl cyanoacrylates, n-butyl cyanoacrylate (GLUBRAN 2), n-hexyl cyanoacrylate (IFABOND), and n-octyl cyanoacrylate (EVOBOND), the cell behavior of the corresponding polymers and the application of these adhesives in the fixation of surgical polypropylene meshes for hernia repair in an animal model of rabbits. The results obtained demonstrate that the curing process depends on the nature of the alkyl residue of the ester group of cyanoacrylate molecules, being the heat of polymerization lower for the octyl derivative in comparison with the hexyl and butyl, and reaching a maximum temperature of 35 °C after a time of mixing with physiological fluids of 60-70 s...
October 5, 2016: Macromolecular Bioscience
Gemma Pascual, Sandra Sotomayor, Marta Rodríguez, Bárbara Pérez-Köhler, Andreé Kühnhardt, Mar Fernández-Gutiérrez, Julio San Román, Juan Manuel Bellón
BACKGROUND: Cyanoacrylate(CA)-based tissue adhesives, although not widely used, are a feasible option to fix a mesh during abdominal hernia repair, due to its fast action and great bond strength. Their main disadvantage, toxicity, can be mitigated by increasing the length of their alkyl chain. The objective was to assess the in vitro cytotoxicity and in vivo biocompatibility in hernia repair of CAs currently used in clinical practice (Glubran(n-butyl) and Ifabond(n-hexyl)) and a longer-chain CA (OCA(n-octyl)), that has never been used in the medical field...
2016: PloS One
Kalpesh Jani
BACKGROUND: We present a randomised control trial to compare suture fixation of the mesh with non-mechanical fixation using n-butyl cyanoacrylate (NBCA) glue for laparoscopic totally extraperitoneal (TEP) hernioplasty. PATIENTS AND METHODS: After a standard dissection for laparoscopic TEP hernioplasty, the mesh was fixed using sutures or NBCA glue to the Cooper's ligament as per the randomised allocation. The primary endpoints were recurrence at 24 months and chronic groin pain...
April 2016: Journal of Minimal Access Surgery
Sandra Barbosa, Tania Nieves, Félix García, Eva Cepeda, Xavier Moll, Alberto Marco, Christine Weis, Pau Turon, Patri Vergara
OBJECTIVE: The aim of this study was to find a proper experimental design and to evaluate n-butyl-2-cyanoacrylate (Histoacryl) as a fixation method for a light-weight and large pore PP mesh (Synthetic PP Mesh-1) using the sheep as an animal model. METHODS: Posterior vaginal implantation by means of episiotomy was used to implant 8 ewes which were evaluated macroscopically and histologically at 3 months (n = 4) and 6 months (n = 4) post-surgery. In previous pilot studies anterior vaginal implantation was evaluated, as well as different synthetic mesh materials, sizes and fixation methods (n = 1 to 3) during three weeks...
2015: BioMed Research International
Gurhan Bas, Orhan Veli Ozkan, Orhan Alimoglu, Ramazan Eryilmaz, Mustafa Sahin, Ismail Okan, Ugur Cevikbas
Diaphragmatic injuries either by blunt or penetrating trauma require prompt surgical intervention and are often exigent to repair. N-butyl-2-cyanoacrylate (n-butyl-2-CA) is a tissue adhesive which has gained wide application in many areas of surgery including emergency. To repair the extensive injuries of the diaphragm it may be necessary the use of synthetic mesh by fixing it with sutures or staples. The use of tissue adhesives may circumvent the potential problems associated with mesh fixation. This study aimed to evaluate the efficacy and safety of tissue adhesives usage for mesh fixation in diaphragmatic injury repair...
2015: International Journal of Clinical and Experimental Medicine
Antonio Darecchio, Paolo Bocchi, Jan F Kukleta
AIM: To achieve full-surface contact of a prosthetic mesh with the abdominal wall (avoiding folds and wrinkles) in laparoscopic ventral/ incisional hernia repair (LVHR/ LIHR) and to fix the mesh with glue using a new surgical technique and a new device, developed for this specific procedure. MATERIAL OF STUDY: New surgical technique associated with a new surgical pneumatic device allows perfect positioning and extension of the intraperitoneal mesh and facilitates the glue application and mesh fixation...
May 2015: Annali Italiani di Chirurgia
R W Knackstedt, J A Dixon, P J O'Neill, F A Herrera
Background. Bilateral reduction mammoplasty is a common plastic surgery procedure that can be complicated by unfavorable scar formation along incision sites. Surgical adhesives can be utilized as an alternative or as an adjunct to conventional suture closures to help achieve good wound tension and provide an adequate barrier with excellent cosmesis. The recently introduced DERMABOND PRINEO Skin Closure System Skin Closure System combines the skin adhesive 2-octyl cyanoacrylate with a self-adhering polyester-based mesh...
2015: Case Reports in Medicine
Yoshiyuki Saito, Keisuke Kubota, Akihiro Okada, Tomoaki Deguchi, Junko Kuroda, Nobuhiro Nitori, Tomohisa Kadomura, Masashi Yoshida, Masaki Kitajima
PURPOSE: We developed a new technique, sutureless mesh fixation, using 2-octyl cyanoacrylate (Dermabond(®), a surgical tissue adhesive) for incisional hernia repair. The objective of this article is to introduce the new technique and to examine whether the technique provides sufficient resistance to abdominal pressure. METHODS: We conducted two tests using a porcine model, a traction experiment and artificial pneumoperitoneum test. In the traction experiment, the adherence properties of Dermabond(®) with mesh and peritoneum were examined using a tissue fragment from a pig...
April 10, 2015: Surgery Today
E Reynvoet, S Van Cleven, I Van Overbeke, K Chiers, P De Baets, R Troisi, F Berrevoet
PURPOSE: The use of glue as mesh fixation in laparoscopic ventral hernia repair (LVHR) significantly reduces fixation associated morbidity. This experiment evaluates the intraperitoneal use of synthetic glue as single mesh fixation. METHODS: A total of 21 sheep were operated using a hernia model with two fascial defects of 2 cm(2) at the linea alba. One week later two polypropylene meshes (Dynamesh®) were implanted laparoscopically, using cyanoacrylate glue (Ifabond®) or conventional fixation (Securestrap®)...
August 2015: Hernia: the Journal of Hernias and Abdominal Wall Surgery
A Burza, R Avantifiori, R Curinga, E Santini, P Delle Site, F Stipa
AIM: The aim of this retrospective study was to compare the results of two different mesh fixation methods in laparoscopic transabdominal preperitoneal hernioplasty (TAPP): tacker vs. synthetic cyanoacrylate glue. METHODS: The study group includes 70 patients with bilateral and monolateral recurrent inguinal hernia undergoing transabdominal preperitoneal repair (TAPP) in the period 2011-2013. A polypropylene mesh was fixed in group A (N.=35) with titanium tacks (EndoUniversal stapler, Covidien) or in group B (N...
December 2014: Minerva Chirurgica
Luis Garcia-Vallejo, Ivan Couto-Gonzalez, Pablo Concheiro-Coello, Beatriz Brea-Garcia, Antonio Taboada-Suarez
In an attempt to find the ideal surgical technique for mesh fixation during laparoscopic total extraperitoneal inguinal hernia repair, we evaluate the use of a synthetic surgical glue (N-butyl-cyanoacrylate-Glubran 2) in an effort to reduce postoperative pain and the complications associated with the use of staples. We have prospectively evaluated 61 consecutive patients (73 hernias) with a minimum follow-up period of 18 months and an average of 29.7 months, without any significant complications present. The majority (59%) only required low dosages of painkillers during the first 24 hours after surgery and have not experienced any cases of chronic pain or recurring hernias in the time period described...
June 2014: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
Mark D Bona, Brian W Arthur
BACKGROUND: The use of cyanoacrylate tissue adhesives in strabismus surgery has been variously successful, depending primarily on achieving adequate bond strength and minimizing extraocular muscle slippage. We investigate a novel approach to this problem, involving cyanoacrylate tissue adhesive on a polyglactin 910 scaffold as a means to secure extraocular muscle to the sclera for strabismus surgery. METHODS: In this experimental laboratory study, butyl-cyanoacrylate was used to fix a polyglactin 910 scaffold to the sclera of cadaver eyes...
February 2014: Journal of AAPOS: the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus
Yoshiaki Sakamoto, Kazuo Kishi
We describe a newly designed technique for the quick, easy, and cost-effective fixation of mesh skin grafts in a range of skin conditions and patients. We fixed the skin graft using octyl-2-cyanoacrylate (Dermabond; Ethicon), which was termed "Dendritic bonding." This technique exhibits several advantages over surgical stapling and suturing with absorbable sutures.
July 2012: Journal of Surgical Technique and Case Report
Somboon Subwongcharoen, Kanchana Ruksakul
BACKGROUND: There has been paramount concern among most surgeons over complications caused by staples in the form of pubic injury and nerve entrapment leading to chronic pain in laparoscopic inguinal hernia repair OBJECTIVE: The present study aimed to compare the use of N-butyl-2-cyanoacrylate (Histoacryl) with that of staples in fixation of mesh in totally extraperitoneal laparoscopic inguinal hernia repair in terms of acute and chronic pain, complications, and recurrence within 1 year MATERIAL AND METHOD: 60 patients were allocated into 2 groups...
March 2013: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
Ming-gang Wang, Mao-lin Tian, Xue-fei Zhao, Yu-sheng Nie, Jie Chen, Ying-mo Shen
BACKGROUND: Our purpose was to compare the recurrence rate and other clinical outcomes of laparoscopic (LS) transabdominal preperitoneal (TAPP) inguinal hernia repair using n-butyl-2-cyanoacrylate (NBCA) for mesh fixation with those of no mesh fixation and mesh fixation with titanium spiral tacks (ST). METHODS: The medical records of patients who received LS TAPP inguinal hernia repair between 2009 and 2012 at our institution were reviewed. Patients were included if the received LS TAPP with either no mesh fixation, mesh fixation with NBCA only, fixation with ST only, or fixation with NBCA + ST...
October 2013: Surgical Endoscopy
D L Sanders, S Waydia
PURPOSE: The technique for fixation of mesh has been attributed to adverse patient and surgical outcomes. Although this has been the subject of vigorous debate in laparoscopic hernia repair, the several methods of fixation in open, anterior inguinal hernia repair have seldom been reviewed. The aim of this systematic review was to determine whether there is any difference in patient-based (recurrence, post-operative pain, SSI, quality of life) or surgical outcomes (operative time, length of operative stay) with different fixation methods in open anterior inguinal hernioplasty...
April 2014: Hernia: the Journal of Hernias and Abdominal Wall Surgery
D Parvizi, H Friedl, M V Schintler, T Rappl, C Laback, M Wiedner, A Vasiljeva, L P Kamolz, S Spendel
BACKGROUND: Abdominoplasty is one of the most commonly performed procedures in plastic surgery. The appearance of the scar is a major factor that contributes to the aesthetic outcome of the procedure and depends largely on the technique of wound closure. The new Prineo™ wound closure system was introduced to combine the effectiveness of 2-octyl cyanoacrylate (Dermabond™) together with a self-adhering mesh. METHODS: Fifty-two women and eight men aged between 21 and 65 years who were scheduled for abdominoplasty were included in the study...
June 2013: Aesthetic Plastic Surgery
Roland Ladurner, Inga Drosse, Costanza Chiapponi, Dominik Bürklein, Volkmar Jansson, Andreas Kokott, Bettina Hoffmann, Günter Ziegler, Wolf Mustchler, Thomas Mussack, Matthias Schieker
BACKGROUND: In this study, we evaluate a new bioadhesive for intra-abdominal onlay mesh fixation of a polypropylene-polyvinylchloride graft. METHODS: Three pieces of a commercially available polypropylene/polyvinylfluoride mesh, each 3 × 3 cm in size, and three pieces of the same mesh coated with a polysaccharide bioadhesive were fixated to the surface of the anterior abdominal wall of 30 New Zealand white rabbits. The fixation was performed either by using four transabdominal Prolene(®) 4/0 sutures, four spiral tacks (Protack 5 mm Tyco), or cyanoacrylate glue (Glubran(®) GEM, Viareggio, Italy)...
June 2013: Surgical Endoscopy
Stanisław Dąbrowiecki, Stanisław Pierściński, Wojciech Szczęsny
INTRODUCTION: With an average incidence rate of 11%, chronic pain is considered the most serious complication of inguinal hernioplasty after surgical site infection. One of the proposed solutions to this problem is to use tissue adhesive for mesh fixation, which helps prevent nerve and tissue damage. AIM: The goal of this study was to compare mesh fixation with the use of sutures vs. adhesive in Lichtenstein's inguinal hernia repair in a randomized, double-blind one-center study...
June 2012: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
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