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Asthma pediatrics

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https://www.readbyqxmd.com/read/29466963/pediatric-severe-asthma-a-case-series-report-and-perspectives-on-anti-ige-treatment
#1
Virginia Mirra, Silvia Montella, Francesca Santamaria
BACKGROUND: The primary goal of asthma management is to achieve disease control for reducing the risk of future exacerbations and progressive loss of lung function. Asthma not responding to treatment may result in significant morbidity. In many children with uncontrolled symptoms, the diagnosis of asthma may be wrong or adherence to treatment may be poor. It is then crucial to distinguish these cases from the truly "severe therapy-resistant" asthmatics by a proper filtering process...
February 21, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29466083/laparoscopic-nissen-fundoplication-an-excellent-treatment-of-gerd-related-respiratory-symptoms-in-children-results-of-a-multicentric-study
#2
Ciro Esposito, Amulya Saxena, Sabine Irtan, Holger Till, Maria Escolino
INTRODUCTION: Respiratory manifestations of gastroesophageal reflux disease (GERD), particularly chronic cough, are being recognized with increased frequency in children. This survey aimed to investigate the efficacy of laparoscopic Nissen fundoplication for treatment of GERD-related respiratory symptoms not responsive to medical therapy in neurological normal children. MATERIALS AND METHODS: We collected data of children with GERD-related respiratory complaints not responsive to medical therapy who underwent laparoscopic Nissen fundoplication in four European centers of Pediatric Surgery over a 10-year period...
February 21, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29461017/medication-adherence-in-pediatric-asthma-a-systematic-review-of-the-literature
#3
REVIEW
Wendy N Gray, Mallory Netz, Andrew McConville, David Fedele, Scott T Wagoner, Megan R Schaefer
OBJECTIVE: To provide a systematic review of correlates of adherence to inhaled corticosteroids (ICS) in pediatric asthma across the individual, family, community, and healthcare system domains. METHODS: Articles assessing medication adherence in pediatric asthma published from 1997 to 2016 were identified using PsychINFO, Medline, and CINAHL. Search terms included asthma, compliance, self-management, adherence, child, and youth. Search results were limited to articles: 1) published in the US; 2) using a pediatric population (0-25 years old); and 3) presenting original data related to ICS adherence...
February 20, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29459526/-the-course-of-asthma-symptoms-in-japanese-children-the-first-report-from-a-multicenter-prospective-cohort-study
#4
Akira Akasawa, Hiroko Watanabe, Mayumi Furukawa, Mari Sasaki, Koichi Yoshida, Hiroshi Odajima, Motohiro Ebisawa, Takao Fujisawa
BACKGROUND: The use of asthma control guidelines and anti-inflammatory drugs have significantly decreased the number of severe asthma cases including death from asthma. However, there are few prospective cohort studies among pediatric asthma patients in Japan describing the course of asthma symptoms with the treatment taken into consideration. METHOD: We recruited a total of 851 children diagnosed with asthma through 90 hospitals and clinics in 2004 to 2006. Questionnaires were posted annually to collect data on their asthma symptoms, treatment and environmental exposures...
2018: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/29458220/incidence-of-autoimmune-and-related-disorders-after-resolution-of-endogenous-cushing-syndrome-in-children
#5
Christina Tatsi, Meg Keil, Charalampos Lyssikatos, Elena Belyavskaya, Constantine A Stratakis, Maya B Lodish
Glucocorticoids are widely used for immunosuppression in autoimmune diseases. After the resolution of hypercortisolemia, the immune system recovers allowing for autoimmune diseases to manifest. Here we investigated the presence of autoimmune and related diseases that developed after cure of endogenous Cushing syndrome (CS) in children. We identified 129 children who were diagnosed and successfully treated for endogenous CS at the National Institutes of Health from 1997 until 2017, and who were followed for at least 6 months after treatment...
February 19, 2018: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29445779/wireless-sensor-dependent-ecological-momentary-assessment-for-pediatric-asthma-mhealth-applications
#6
Chris M Buonocore, Rosemary A Rocchio, Alfonso Roman, Christine E King, Majid Sarrafzadeh
Pediatric asthma is a prevalent chronic disease condition that can benefit from wireless health systems through constant symptom management. In this paper, we propose a smart watch based wireless health system that incorporates wireless sensing and ecological momentary assessment (EMA) to determine an individual's asthma symptoms. Since asthma is a multifaceted disease, this approach provides individualized symptom assessments through various physiological and environmental wireless sensor based EMA triggers specific to common asthma exacerbations...
July 2017: ...IEEE...International Conference on Connected Health: Applications, Systems and Engineering Technologies
https://www.readbyqxmd.com/read/29445636/economic-burden-of-pediatric-asthma-annual-cost-of-disease-in-iran
#7
Laleh Sharifi, Raheleh Dashti, Zahra Pourpak, Mohammad Reza Fazlollahi, Masoud Movahedi, Zahra Chavoshzadeh, Habib Soheili, Saied Bokaie, Anoushiravan Kazemnejad, Mostafa Moin
Background: Asthma is the first cause of children hospitalization and need for emergency and impose high economic burden on the families and governments. We aimed to investigate the economic burden of pediatric asthma and its contribution to family health budget in Iran. Methods: Overall, 283 pediatric asthmatic patients, who referred to two tertiary pediatric referral centers in Tehran capital of Iran, included from 2010-2012. Direct and indirect asthma-related costs were recorded during one-year period...
February 2018: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/29441827/urinary-bisphenol-a-concentrations-in-relation-to-asthma-in-a-sample-of-egyptian-children
#8
M M Youssef, Ems El-Din, M M AbuShady, N R El-Baroudy, T A Abd El Hamid, A F Armaneus, A S El Refay, J Hussein, D Medhat, Y A Latif
BACKGROUND: Bronchial asthma is one of the top disabling diseases in pediatrics. Limited research has been studied the association of the widely used plastic monomer bisphenol A (BPA) with childhood asthma. OBJECTIVE: To compare the levels of urinary BPA in asthmatic and control children and to investigate the implication of BPA among other risk factors for the development of asthma. SUBJECTS AND METHODS: This case-control study included 97 children (45 asthmatic and 52 healthy controls) aged 3-8 years...
January 1, 2018: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/29440128/a-quality-improvement-intervention-to-improve-inpatient-pediatric-asthma-controller-accuracy
#9
Alexander H Hogan, Deepa Rastogi, Michael L Rinke
OBJECTIVES: Our objective was to investigate if a rigorous quality improvement (QI) intervention could increase accuracy of pediatric asthma controller medications on discharge from an inpatient hospitalization. METHODS: Our interprofessional QI team developed interventions such as improving documentation and creating standardized language to ensure patients were discharged on an appropriate asthma controller medication and improve assessment of asthma symptom control...
February 13, 2018: Hospital Pediatrics
https://www.readbyqxmd.com/read/29437489/controller-adherence-following-hospital-discharge-in-high-risk-children-a-pilot-randomized-trial-of-text-message-reminders
#10
Chén C Kenyon, Siobhan M Gruschow, William O Quarshie, Heather Griffis, Michelle C Leach, Joseph J Zorc, Tyra C Bryant-Stephens, Victoria A Miller, Chris Feudtner
OBJECTIVE: To assess the feasibility of a mobile health, inhaled corticosteroid (ICS) adherence reminder intervention and to characterize adherence trajectories immediately following severe asthma exacerbation in high-risk urban children with persistent asthma. METHODS: Children aged 2-13 with persistent asthma were enrolled in this pilot randomized controlled trial during an asthma emergency department (ED) visit or hospitalization. Intervention arm participants received daily text message reminders for 30 days, and both arms received electronic sensors to measure ICS use...
February 13, 2018: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/29434271/adherence-and-quality-of-life-in-adults-and-children-during-3-years-of-slit-treatment-with-grazax-a-real-life-study
#11
Hampus Kiotseridis, Peter Arvidsson, Vibeke Backer, Vagn Braendholt, Alf Tunsäter
Respiratory allergic disease represents a global health problem, 30% of the population suffers from allergic rhinoconjunctivitis and 20% suffer from asthma. Allergy immunotherapy induce immunological tolerance and thereby modify the response to allergens and sublingual immunotherapy (SLIT) offers the possibility of home administration of allergen therapy, but adherence is more uncertain. The aim of the study was to investigate the adherence with GRAZAX in adults and children ≥ 5 years during three consecutive years of treatment...
February 12, 2018: NPJ Primary Care Respiratory Medicine
https://www.readbyqxmd.com/read/29433792/clinical-characteristics-of-influenza-virus-induced-lower-respiratory-infection-during-the-2015-to-2016-season
#12
Kazuhiro Uda, Kensuke Shoji, Chitose Koyama-Wakai, Munehiro Furuichi, Noriyasu Iwase, Seiichiro Fujisaki, Shinji Watanabe, Isao Miyairi
BACKGROUND: Influenza A(H1N1)pdm09 virus infections often manifest severe respiratory symptoms, particularly in patients with a past history of allergic disease. Most of these findings were reported during the 2009 pandemic. The purpose of this study was to detail the clinical characteristics of influenza virus-induced lower respiratory infection (LRI) during the A(H1N1)pdm09-predominant 2015-2016 season. METHODS: We retrospectively reviewed the clinical characteristics of influenza-induced LRI cases in children admitted to a tertiary children's hospital...
February 9, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29432207/prevalence-of-comorbid-conditions-pre-existing-and-diagnosed-at-a-tertiary-care-pediatric-weight-management-clinic
#13
Griselle Leon, Elizabeth de Klerk, Josephine Ho, Michelle Jackman, Raylene A Reimer, Kimberly E Connors, Paola Luca
BACKGROUND: Childhood obesity places individuals at risk for a multitude of physical and mental health problems. The aim of this study was to assess the prevalence of obesity related comorbidities diagnosed prior to and after attending a tertiary care pediatric weight management clinic. METHODS: A cross sectional retrospective chart review of patients 2-17 years old seen in the weight management clinic at Alberta Children's Hospital from May 2012 to May 2014. RESULTS: A total of 199 patients were included in the review...
February 13, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29431176/phd-forum-multimodal-iot-and-emr-based-smart-health-application-for-asthma-management-in-children
#14
Utkarshani Jaimini
According to a study done in 2014 by National Health Interview Survey around 6.3 million children in United States suffer from asthma [1]. Asthma remains one of the leading reasons for pediatric admissions to children's hospitals, and has a prevalence rate of approximately 10% in children and it leads to missed days from school and other societal costs. This occurs despite improved medications to control asthma symptoms. Asthma management is challenging as it involves understanding asthma causes and avoiding asthma triggers that are both multi-factorial and individualistic in nature...
May 2017: Proc Int Conf Smart Comput SMARTCOMP
https://www.readbyqxmd.com/read/29427984/controlling-the-risk-domain-in-pediatric-asthma-through-personalized-care
#15
William C Anderson, Stanley J Szefler
Strategies to control the risk domain of NHLBI EPR-3 (National Heart, Lung, and Blood Institute Expert Panel Report-3) asthma guidelines, which includes exacerbations requiring systemic corticosteroids, reduction in lung growth, and progressive loss of lung function, and treatment-related adverse effects, are evolving in children and adolescents. Increasing evidence demonstrates that children and adolescents with asthma are at risk of a reduction in lung growth, leading to lower lung function and potentially chronic obstructive pulmonary disease as adults...
February 2018: Seminars in Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29421950/current-and-future-challenges-in-pediatric-severe-asthma
#16
Amelia Licari, Gian Luigi Marseglia
No abstract text is available yet for this article.
February 8, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29420850/chitotriosidase-inhibits-allergic-asthmatic-airways-via-regulation-of-tgf-%C3%AE-expression-and-foxp3-treg-cells
#17
Jung Yeon Hong, Mina Kim, In Suk Sol, Kyung Won Kim, Chang-Min Lee, Jack A Elias, Myung Hyun Sohn, Chun Geun Lee
BACKGROUND: Chitotriosidase (Chitnase 1, Chit1), a major true chitinase in humans, is induced in childhood asthma and has been implicated in the pathogenesis of a variety of inflammatory and tissue remodeling responses. We hypothesized that Chit1 plays a significant role in the pathogenesis of allergic asthma. To identify the role of Chit1, the mechanisms that underlie these contributions and the relevance of these murine findings to childhood asthma. METHODS: Wild type and Chit1-deficient mice and cells in culture were used to define the roles of Chit1 in models of allergic adaptive Th2 inflammation...
February 8, 2018: Allergy
https://www.readbyqxmd.com/read/29414895/a-case-of-spontaneous-pneumomediastinum-with-subcutaneous-emphysema-in-children
#18
Said Benlamkaddem, Mohamed Adnane Berdai, Smael Labib, Mustapha Harandou
Spontaneous pneumomediastinum is defined as free air or gas contained within the mediastinum, which almost invariably originates from the alveolar space or the conducting airways. It is rare in pediatric patients; however, occasional cases are reported to result from forced Valsalva's maneuver due to cough, emesis, a first attack of wheeze, or asthma exacerbations. We report the case of a 7-year-old previously healthy girl, with a history of persistent dry cough one day before, who was brought to our unit with face, neck and chest swelling...
February 7, 2018: Children
https://www.readbyqxmd.com/read/29411715/evaluation-of-fractioned-nitric-oxide-in-chronic-cough-patients
#19
Y Yildiz, M Igde
INTRODUCTION: Cough exceeding 3-8 weeks was defined as chronic cough in various guides. Asthma is the most common cause of chronic-specific cough. Causes other than asthma include prolonged bacterial bronchitis and upper airway cough syndrome (UACS). Nitric oxide (NO) causes vascular smooth muscle relaxation, bronchodilation, and oxidant effects via its metabolite, peroxynitrite. An increase in NO results in inflammation, vasodilatation, and bronchial edema. MATERIALS AND METHODS: The study group included 90 patients aged 6-17 years selected from individuals presenting to the Pediatric Immunology and Allergic Diseases Clinic with cough persisting for 4 weeks and 30 other patients representing to the control group...
January 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29410045/lifetime-air-pollution-exposure-and-asthma-in-a-pediatric-birth-cohort
#20
M B Rice, S L Rifas-Shiman, A A Litonjua, M W Gillman, N Liebman, I Kloog, H Luttmann-Gibson, B A Coull, J Schwartz, P Koutrakis, E Oken, M A Mittleman, D R Gold
No abstract text is available yet for this article.
February 1, 2018: Journal of Allergy and Clinical Immunology
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