keyword
MENU ▼
Read by QxMD icon Read
search

Pancreatic cancer surgery

keyword
https://www.readbyqxmd.com/read/29450752/racial-and-socioeconomic-differences-in-the-use-of-high-volume-commission-on-cancer-accredited-hospitals-for-cancer-surgery-in-the-united-states
#1
Nabil Wasif, David Etzioni, Elizabeth B Habermann, Amit Mathur, Barbara A Pockaj, Richard J Gray, Yu-Hui Chang
BACKGROUND: Although major cancer surgery at a high-volume hospital is associated with lower postoperative mortality, the use of such hospitals may not be equally distributed. OBJECTIVE: Our aim was to study socioeconomic and racial differences in cancer surgery at Commission on Cancer (CoC)-accredited high-volume hospitals. METHODS: The National Cancer Database (NCDB) was used to identify patients undergoing surgery for colon, esophageal, liver, and pancreatic cancer from 2003 to 2012...
February 15, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29445028/evaluation-of-treatment-patterns-and-survival-outcomes-in-elderly-pancreatic-cancer-patients-a-surveillance-epidemiology-and-end-results-medicare-analysis
#2
Walid L Shaib, Jeb S Jones, Michael Goodman, Juan M Sarmiento, Shishir K Maithel, Kenneth Cardona, Sujata Kane, Christina Wu, Olatunji B Alese, Bassel F El-Rayes
BACKGROUND: Management of pancreatic cancer (PC) in elderly patients is unknown; clinical trials exclude patients with comorbidities and those of extreme age. This study evaluated treatment patterns and survival outcomes in elderly PC patients using linked Surveillance, Epidemiology, and End Results (SEER) and Medicare data. MATERIALS AND METHODS: Histology codes 8140, 8500, 8010, 8560, 8490, 8000, 8260, 8255, 8261, 8263, 8020, 8050, 8141, 8144, 8210, 8211, or 8262 in Medicare Parts A and B were identified...
February 14, 2018: Oncologist
https://www.readbyqxmd.com/read/29444581/-the-effect-of-circulating-tumor-cells-on-the-survival-of-patients-with-pancreatic-cancer-5-year-results
#3
L Bébarová, P Skalický, J Srovnal, A Prokopová, J Zapletalová, M Hajdúch, M Loveček
INTRODUCTION: Pancreatic cancer (PDAC) is one of the most aggressive malignancies. Its incidence increases worldwide and, despite the developments in cancer research, mortality rates have not decreased. Poor prognosis of the disease is due to many factors, mainly late diagnosis. Distant metastases and peritoneal carcinomatosis are caused by hematogenous and lymphogenous spreading of the tumorous cells. One of the factors that may influence patient survival are so-called circulating tumor cells (CTCs)...
2018: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/29442238/two-point-measurement-of-amylase-in-drainage-fluid-predicts-severe-postoperative-pancreatic-fistula-after-gastric-cancer-surgery
#4
Satoshi Kamiya, Naoki Hiki, Koshi Kumagai, Michitaka Honda, Souya Nunobe, Manabu Ohashi, Takeshi Sano, Toshiharu Yamaguchi
BACKGROUND: Early identification of patients at risk of postoperative pancreatic fistula (POPF) allows appropriate management after gastrectomy. Although some reports have suggested a correlation between POPF and the concentration of amylase in drained abdominal fluid (D-AMY), this has not been proven to impact sufficiently on clinical decision-making. A sustained high level of D-AMY is often assumed to be due to unsatisfactory drainage or excessive pancreatic leakage. We assessed the clinical utility of measuring D-AMY on postoperative day (POD) 1 and POD3 for prediction of POPF...
February 13, 2018: Gastric Cancer
https://www.readbyqxmd.com/read/29442211/circulating-tumor-cells-predict-occult-metastatic-disease-and-prognosis-in-pancreatic-cancer
#5
Colin M Court, Jacob S Ankeny, Shonan Sho, Paul Winograd, Shuang Hou, Min Song, Zev A Wainberg, Mark D Girgis, Thomas G Graeber, Vatche G Agopian, Hsian-Rong Tseng, James S Tomlinson
BACKGROUND: Occult metastatic tumors, below imaging thresholds, are a limitation of staging systems that rely on cross-sectional imaging alone and are a cause of the routine understaging of pancreatic ductal adenocarcinomas (PDACs). We investigated circulating tumor cells (CTCs) as a preoperative predictor of occult metastatic disease and as a prognostic biomarker for PDAC patients. EXPERIMENTAL DESIGN: A total of 126 patients (100 with cancer, 26 with benign disease) were enrolled in our study and CTCs were identified and enumerated from 4 mL of venous blood using the microfluidic NanoVelcro assay...
February 13, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29441475/robot-assisted-distal-gastrectomy-with-lymph-node-dissection-for-gastric-cancer-in-a-patient-with-situs-inversus-partialis-a-case-report-with-video-file
#6
Yuki Aisu, Yoshio Kadokawa, Shigeru Kato, Daiki Yasukawa, Yusuke Kimura, Tomohide Hori
BACKGROUND: Situs inversus is a rare congenital condition that is currently classified into two types: complete situs inversus (situs inversus totalis, SIT) and partial situs inversus (situs inversus partialis, SIP). In SIP patients, some organs are inverted and others are in their expected position, and individual patient variation in organ position increases surgical difficulty. Several surgeons have performed laparoscopic or robotic surgeries in situs inversus patients, but almost all were SIT patients...
February 13, 2018: Surgical Case Reports
https://www.readbyqxmd.com/read/29435751/impact-of-anatomical-position-of-the-pancreas-on-postoperative-complications-and-drain-amylase-concentrations-after-laparoscopic-distal-gastrectomy-for-gastric-cancer
#7
Koshi Kumagai, Naoki Hiki, Souya Nunobe, Satoshi Kamiya, Masahiro Tsujiura, Satoshi Ida, Manabu Ohashi, Toshiharu Yamaguchi, Takeshi Sano
BACKGROUND: Laparoscopic surgery for gastric cancer requires traction or compression of the pancreas, with the extent depending on the anatomical position of the pancreas. This study investigated the impact of the position of the pancreas on postoperative complications and drain amylase concentrations after laparoscopic distal gastrectomy (LDG). METHODS: Gastric cancer patients who underwent LDG were assessed retrospectively. The following anatomical parameters were measured retrospectively in preoperative computed tomography sagittal projections: the length of the vertical line between the pancreas and the aorta (P-A length), representing the height of the slope looking down the celiac artery from the top of the pancreas, and the angle between a line drawn from the upper border of the pancreas to the root of the celiac artery and the aorta (UP-CA angle), representing the steepness of the slope...
February 12, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29434873/mechanisms-by-which-cxcr4-cxcl12-cause-metastatic-behavior-in-pancreatic-cancer
#8
Jianbo Zhang, Chengxin Liu, Xinkai Mo, Huan Shi, Sheng Li
C-X-C motif chemokine receptor (CXCR) 4/CXCL12 is associated with tumor invasion and metastasis in pancreatic cancer. The present study aimed to investigate the possible mechanisms behind this process by studying the association between the expression of CXCR4 and numerous molecular markers. A total of 60 patients with pancreatic cancer who had been treated with radical surgery between July 2012 and February 2016 were included in the present study. The expression of CXCR4/CXCL12 in primary pancreatic cancer lesions, tissues adjacent to cancerous tissue, non-cancerous pancreatic tissues and in the surrounding lymph nodes was evaluated by immunohistochemistry...
February 2018: Oncology Letters
https://www.readbyqxmd.com/read/29428109/ca19-9-level-determines-therapeutic-modality-in-pancreatic-cancer-patients-with-para-aortic-lymph-node-metastasis
#9
Tadafumi Asaoka, Atsushi Miyamoto, Sakae Maeda, Naoki Hama, Masanori Tsujie, Masataka Ikeda, Mitsugu Sekimoto, Shoji Nakamori
BACKGROUND: In general, para-aortic lymph node (LN16) metastasis has been considered as a contraindication for pancreatic resection. However, some pancreatic cancer patients with LN16 metastasis have been reported to survive for longer than expected after pancreatectomy. The purpose of this study was to determine whether pancreatic cancer patients with LN16 metastasis might benefit from surgery. METHODS: We retrospectively reviewed 201 consecutive patients with invasive pancreatic ductal adenocarcinoma who underwent surgery at Osaka National Hospital between April 2003 and December 2012...
February 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/29428107/evaluation-of-the-8th-ajcc-staging-system-for-pathologically-versus-clinically-staged-pancreatic-adenocarcinoma-a-time-to-revisit-a-dogma
#10
Omar Abdel-Rahman
BACKGROUND: The 8th edition of the American Joint Committee on Cancer (AJCC) staging system for pancreatic exocrine adenocarcinoma has been released. The current study seeks to assess the 7th and 8th editions among patients registered within the surveillance, epidemiology and end results (SEER) database. METHODS: SEER database (2010-2013) has been accessed through SEER*Stat program and AJCC 8th edition stages were reconstructed utilizing the collaborative stage descriptions...
February 2018: Hepatobiliary & Pancreatic Diseases International: HBPD INT
https://www.readbyqxmd.com/read/29428036/span-1-and-ca19-9-as-predictors-of-early-recurrence-and-lymph-node-metastasis-for-patients-with-invasive-pancreatic-cancer-after-pancreatectomy
#11
Tetsunosuke Shimizu, Mitsuhiro Asakuma, Atsushi Tomioka, Yoshihiro Inoue, Fumitoshi Hirokawa, Michihiro Hayashi, Kazuhisa Uchiyama
Because pancreatic cancer is a disease with a dismal prognosis due to the high rate of early recurrence even after curative surgery, selecting the most effective treatment in an individual requires preoperative assessment of the tumor characteristics, including the potential for early recurrence. The study cohort included 84 patients undergoing surgical resection of pancreatic cancer. Univariate and multivariate analyses were conducted to identify the risk factors for early recurrence within six months after curative resection...
January 1, 2018: American Surgeon
https://www.readbyqxmd.com/read/29426635/neoadjuvant-therapy-affects-margins-and-margins-affect-all-perioperative-and-survival-outcomes-in-resected-pancreatic-adenocarcinoma
#12
Susanna W L de Geus, Gyulnara G Kasumova, Teviah E Sachs, Sing Chau Ng, Tara S Kent, A James Moser, Alexander L Vahrmeijer, Mark P Callery, Jennifer F Tseng
BACKGROUND: Resection margin status is an important prognostic factor in pancreatic cancer; however, the impact of positive resection margins in those who received neoadjuvant therapy remains unclear. The current study investigates the prognostic impact of resection margin status after neoadjuvant therapy and pancreaticoduodenectomy for patients with pancreatic adenocarcinoma. METHODS: Patients who underwent pancreaticoduodenectomy for pancreatic adenocarcinoma between 2006 and 2013 were identified from the National Cancer Database...
February 6, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29425826/correlation-of-clinical-and-pathological-staging-and-response-to-neoadjuvant-therapy-in-resected-pancreatic-cancer
#13
Katelin A Mirkin, Erin K Greenleaf, Christopher S Hollenbeak, Joyce Wong
BACKGROUND: Neoadjuvant therapy (NAT) has been increasingly employed to optimize outcomes in pancreatic cancer; however, little is known about its pathologic impact. METHODS: The National Cancer Data Base (2003-2011) was retrospectively reviewed for patients with pancreatic carcinoma who underwent initial surgery or NAT followed by resection. Response to NAT, determined by comparing clinical and pathologic stage, and survival were evaluated. RESULTS: 16,087 patients underwent initial pancreatectomy and 2307 patients received NAT...
February 6, 2018: International Journal of Surgery
https://www.readbyqxmd.com/read/29425780/risk-of-pancreatic-cancer-in-patients-with-pancreatic-cysts-and-family-history-of-pancreatic-cancer
#14
Saurabh S Mukewar, Ayush Sharma, Nissy Phillip, Ridhi Gupta, Anupama Aryal-Khanal, Nicolo de Pretis, Vincent Anani, Felicity T Enders, Joseph J Larson, Naoki Takahashi, Michael J Levy, Mark Topazian, Randall K Pearson, Santhi S Vege, Suresh T Chari
BACKGROUND & AIMS: A diagnosis of pancreatic cancer in a first-degree relative increases an individuals' risk of this cancer. However, it is not clear whether this cancer risk increases in individuals with pancreatic cystic lesions who have a first-degree relative with pancreatic cancer. The Fukuoka criteria are used to estimate risk of pancreatic cancer for patients with pancreatic cystic lesions: individuals with cysts with high risk or worrisome features (Fukuoka positive) have a higher risk of pancreatic cancer than individuals without these features (Fukuoka negative)...
February 6, 2018: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29416354/nomogram-for-predicting-survival-in-patients-with-pancreatic-cancer
#15
Wei Song, Dong-Liu Miao, Lei Chen
Background: The purpose of this study was to develop a nomogram to predict cancer-specific survival (CSS) in pancreatic cancer (PC). Patients and methods: We used the Surveillance, Epidemiology, and End Results (SEER) database to analyze 53,028 patients diagnosed with PC from 2004 to 2014 and randomly divided them into the training (n=26,583) cohort and validation (n=26,445) cohort. Univariate and multivariate analyses were used to select independent prognostic factors...
2018: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29416321/perioperative-outcome-of-elderly-versus-younger-patients-undergoing-major-hepatic-or-pancreatic-surgery
#16
Qiang Lu, Jian-Wen Lu, Zheng Wu, Xue-Min Liu, Jian-Hui Li, Jian Dong, Guo-Zhi Yin, Yi Lv, Xu-Feng Zhang
Objective: The aim of this study was to determine the safety of elderly cancer patients (≥70 years) undergoing hepatic resection (HR) or pancreaticoduodenectomy (PD) in comparison with younger adults (<70 years). Methods: A total of 1,012 consecutive patients undergoing HR or PD were included. The incidence and severity of morbidity were documented within 30 days postoperatively and compared between elderly and younger groups. Risk factors associated with postoperative morbidity were investigated by multivariate logistic regression analysis...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29414805/a-novel-approach-for-hepatic-arterial-reconstruction-after-total-pancreatectomy-with-common-hepatic-artery-resection-using-inferior-phrenic-artery
#17
Takatsugu Matsumoto, Keiichi Kubota, Taku Aoki, Takayuki Shimizu, Shozo Mori, Masato Kato, Hirotaka Asato
BACKGROUND/AIMS: Because of the anatomical characteristics, pancreatic cancers (PC) can easily invade to visceral vessels such as celiac artery, superior mesenteric artery, common hepatic artery (CHA) and portal vein, which makes curative resection difficult. In this study, we report an R0 resection for locally advanced PC by total pancreatectomy, combined resection of CHA, and reconstruction of hepatic artery using autologous left inferior phrenic artery (IPA). METHODS: A 47-year-old woman with complaints of low back pain was referred to our department...
February 7, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/29405509/introduction-and-practical-approach-to-exocrine-pancreatic-insufficiency-for-the-practicing-clinician
#18
REVIEW
Mohamed O Othman, Diala Harb, Jodie A Barkin
AIMS: In exocrine pancreatic insufficiency (EPI), the quantity and/or activity of pancreatic digestive enzymes are below the levels required for normal digestion, leading to maldigestion and malabsorption. Diagnosis of EPI is often challenging because the characteristic signs and symptoms overlap with those of other gastrointestinal conditions. Additionally, there is no single convenient, or specific diagnostic test for EPI. The aim of this review is to provide a framework for differential diagnosis of EPI vs other malabsorptive conditions...
February 5, 2018: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/29405026/-care-plan-for-resuming-the-physical-activity-of-patients-with-pancreatic-cancer-and-diabetes-after-surgery
#19
Hui-Ting Yang, Mei-Chih Wu, Shiow-Ching Shun
Many barriers influence the ability of postoperative cancer patients to reengage in normal physical activities. Training programs have been shown to be effective in helping restore physical activity in patients and in reducing the care burdens of family members. Nurses cannot use physical activity guidelines in their care plan to assess individual needs. The clinical practice guidelines for physical activity in survivorship were published by the National Comprehensive Cancer Network (NCCN) in 2016. These guidelines are used to assess patients' physical status, curable factors, physical barriers, and risk of postoperative pancreatic cancer and diabetes...
February 2018: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/29402376/pet-panc-multicentre-prospective-diagnostic-accuracy-and-health-economic-analysis-study-of-the-impact-of-combined-modality-18fluorine-2-fluoro-2-deoxy-d-glucose-positron-emission-tomography-with-computed-tomography-scanning-in-the-diagnosis-and-management-of
#20
Paula Ghaneh, Robert Hanson, Andrew Titman, Gill Lancaster, Catrin Plumpton, Huw Lloyd-Williams, Seow Tien Yeo, Rhiannon Tudor Edwards, Colin Johnson, Mohammed Abu Hilal, Antony P Higginson, Tom Armstrong, Andrew Smith, Andrew Scarsbrook, Colin McKay, Ross Carter, Robert P Sutcliffe, Simon Bramhall, Hemant M Kocher, David Cunningham, Stephen P Pereira, Brian Davidson, David Chang, Saboor Khan, Ian Zealley, Debashis Sarker, Bilal Al Sarireh, Richard Charnley, Dileep Lobo, Marianne Nicolson, Christopher Halloran, Michael Raraty, Robert Sutton, Sobhan Vinjamuri, Jonathan Evans, Fiona Campbell, Jon Deeks, Bal Sanghera, Wai-Lup Wong, John P Neoptolemos
BACKGROUND: Pancreatic cancer diagnosis and staging can be difficult in 10-20% of patients. Positron emission tomography (PET)/computed tomography (CT) adds precise anatomical localisation to functional data. The use of PET/CT may add further value to the diagnosis and staging of pancreatic cancer. OBJECTIVE: To determine the incremental diagnostic accuracy and impact of PET/CT in addition to standard diagnostic work-up in patients with suspected pancreatic cancer...
February 2018: Health Technology Assessment: HTA
keyword
keyword
52349
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"