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https://www.readbyqxmd.com/read/29210596/mayo-registry-for-telemetry-efficacy-in-arrest-study-an-evaluation-of-the-feasibility-of-the-do-not-intubate-code-status
#1
David Snipelisky, Adrian Dumitrascu, Jordan Ray, Archana Roy, Gautam Matcha, Dana Harris, Tyler Vadeboncoeur, Fred Kusumoto, M Caroline Burton
INTRODUCTION: Guidelines recommend discussing code status with patients on hospital admission. No study has evaluated the feasibility of a full code with do not intubate (DNI) status. METHODS: A retrospective analysis of patients who experienced a cardiopulmonary arrest was performed between May 1, 2008 and June 20, 2014. A descriptive analysis was created based on whether patients required mechanical ventilatory support during the hospitalization and comparisons were made between both patient subsets...
December 6, 2017: Acute Cardiac Care
https://www.readbyqxmd.com/read/29208210/evaluation-of-the-delta-neutrophil-index-from-an-automated-blood-cell-analyser-in-septic-dogs
#2
R Troìa, C Agnoli, S Calipa, S Segalina, E Murgia, M Gruarin, F Dondi, M Giunti
Immature granulocytes (IG) are a marker of severe inflammatory states in human beings and animals, and have been linked to a diagnosis of sepsis and poor prognosis. The delta neutrophil index (DNI), automatically calculated by a haematological analyser, provides an estimate of circulating IG. In particular, an increased DNI value has been associated with the severity of sepsis, and mortality, in critically ill human beings. The aims of this study were to determine the DNI reference interval (RI) in healthy dogs, and to evaluate its diagnostic and prognostic significance in dogs with sepsis...
December 2017: Veterinary Journal
https://www.readbyqxmd.com/read/29184881/which-patients-with-intestinal-obstruction-need-surgery-the-delta-neutrophil-index-as-an-early-predictive-marker
#3
Haemin Lee, Im-Kyung Kim, Man Ki Ju
Purpose: Predicting the need for surgical intervention among patients with intestinal obstruction is challenging. The delta neutrophil index (DNI) has been suggested as a useful marker of immature granulocytes, which indicate an infection or sepsis. In this study, we evaluated the impact of the DNI as an early predictor of operation among patients with intestinal obstruction. Methods: A total of 171 patients who were diagnosed with postoperative intestinal obstruction were enrolled in this study...
November 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29181984/from-positive-to-negative-zero-field-splitting-in-a-series-of-strongly-magnetically-anisotropic-mononuclear-metal-complexes
#4
Ghénadie Novitchi, Shangda Jiang, Sergiu Shova, Fatima Rida, Ivo Hlavička, Milan Orlita, Wolfgang Wernsdorfer, Rana Hamze, Cyril Martins, Nicolas Suaud, Nathalie Guihéry, Anne-Laure Barra, Cyrille Train
A series of mononuclear [M(hfa)2(pic)2] (Hhfa = 1,1,1,5,5,5-hexafluoro-2,4-pentanedione; pic = 4-methylpyridine; M = FeII, CoII, NiII, ZnII) compounds were obtained and characterized. The structures of the complexes have been resolved by single-crystal X-ray diffraction, indicating that, apart from the zinc derivative, the complexes are in a trans configuration. Moreover, a dramatic lenghthening of the Fe-N distances was observed, whereas the nickel(II) complex is almost perfectly octahedral. The magnetic anisotropy of these complexes was thoroughly studied by direct-current (dc) magnetic measurements, high-field electron paramagnetic resonance, and infrared (IR) magnetospectroscopy: the iron(II) derivative exhibits an out-of-plane anisotropy (DFe = -7...
November 28, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/29159371/care-planning-for-inpatients-referred-for-palliative-care-consultation
#5
Kara Bischoff, David L O'Riordan, Angela K Marks, Rebecca Sudore, Steven Z Pantilat
Importance: Care planning is a critical function of palliative care teams, but the impact of advance care planning and goals of care discussions by palliative care teams has not been well characterized. Objective: To describe the population of patients referred to inpatient palliative care consultation teams for care planning, the needs identified by palliative care clinicians, the care planning activities that occur, and the results of these activities. Design, Setting, and Participants: This was a prospective cohort study conducted between January 1, 2013, and December 31, 2016...
November 20, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/29154249/deep-neck-infections-review-of-263-cases
#6
Alise Adoviča, Linda Veidere, Marks Ronis, Gunta Sumeraga
OBJECTIVES: In patients hospitalized due to deep neck infections (DNIs), to investigate the association between demographic parameters, etiology, and localization of abscesses and/or phlegmons, complications, comorbidities, treatment, and bacterial cultures. METHODS: We analyzed data of 263 patients that were hospitalized from January 1, 2012, to December 31, 2015, due to deep neck space phlegmons and/or abscesses. We performed statistical analysis with the SPSS 22...
October 30, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/29146994/usefulness-of-the-delta-neutrophil-index-to-predict-30-day-mortality-in-patients-with-st-segment-elevation-myocardial-infarction
#7
Taeyoung Kong, Tae Hoon Kim, Yoo Seok Park, Sung Phil Chung, Hye Sun Lee, Jung Hwa Hong, Jong Wook Lee, Je Sung You, Incheol Park
This study aimed to evaluate the association between the delta neutrophil index (DNI), which reflects immature granulocytes, and the severity of ST-elevation myocardial infarction (STEMI), as well as to determine the significance of the DNI as a prognostic marker for early mortality and other clinical outcomes in patients with STEMI who underwent reperfusion. This retrospective, observational cohort study was conducted using patients prospectively integrated in a critical pathway program for STEMI. We included 842 patients diagnosed with STEMI who underwent primary percutaneous coronary intervention (pPCI)...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29134730/role-of-central-versus-peripheral-opioid-system-in-antinociceptive-and-anti-inflammatory-effect-of-botulinum-toxin-type-a-in-trigeminal-region
#8
V Drinovac Vlah, B Filipović, L Bach-Rojecky, Z Lacković
BACKGROUND: Although botulinum toxin type A (BT-A) is approved for chronic migraine treatment, its site and mechanism of action are still elusive. Recently our group discovered that suppression of CGRP release from dural nerve endings might account for antimigraine action of pericranially injected BT-A. We demonstrated that central antinociceptive effect of BT-A in sciatic region involves endogenous opioid system as well. Here we investigated possible interaction of BT-A with endogenous opioid system within the trigeminal region...
November 13, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29091955/delta-neutrophil-index-as-a-promising-prognostic-marker-of-emergent-surgical-intervention-for-acute-diverticulitis-in-the-emergency-department
#9
Hee Seung Kang, Yong Sung Cha, Kyung Hye Park, Sung Oh Hwang
BACKGROUND: Early identification of patients with acute diverticulitis who require emergent surgical intervention in the emergency department (ED) is important to the physician. Although computed tomography (CT) has an important role in evaluating the severity of diverticulitis, its findings alone may not predict the need for emergent surgical intervention in all patients with acute diverticulitis in the ED. Serum inflammation markers may help to differentiate severity of acute diverticulitis and predict the need for surgical intervention in clinical practice...
2017: PloS One
https://www.readbyqxmd.com/read/29036031/value-of-the-delta-neutrophil-index-for-predicting-28-day-mortality-in-patients-with-acute-pulmonary-embolism-in-the-emergency-department
#10
Taeyoung Kong, Yoo Seok Park, Hye Sun Lee, Sinae Kim, Jong Wook Lee, Gina Yu, Claire Eun, Je Sung You, Hyun Soo Chung, Incheol Park, Sung Phil Chung
PURPOSE: Acute pulmonary embolism (PE), frequently seen in the emergency department (ED), is a leading cause of cardiovascular morbidity and mortality. The delta neutrophil index (DNI) reflects the fraction of circulating immature granulocytes as a component of the systemic inflammatory response syndrome criteria. The pathogenesis of acute PE is significantly associated with inflammation. The aim of the study was to investigate the clinical usefulness of the DNI as a marker of severity in patients with acute PE admitted to the ED...
October 14, 2017: Shock
https://www.readbyqxmd.com/read/28976129/acute-effects-of-low-level-laser-therapy-660-nm-on-oxidative-stress-levels-in-diabetic-rats-with-skin-wounds
#11
Amanda Silveira Denadai, Ricardo Dutra Aydos, Iandara Schettert Silva, Larissa Olmedo, Bruno Mendonça de Senna Cardoso, Baldomero Antonio Kato da Silva, Paulo de Tarso Camillo de Carvalho
BACKGROUND: Laser therapy influences oxidative stress parameters such as the activity of antioxidant enzymes and the production of reactive oxygen species. OBJECTIVE: To analyze the effects of low-level laser therapy on oxidative stress in diabetics rats with skin wounds. METHODS: Thirty-six animals were divided into 4 groups: NDNI: non-diabetic rats with cutaneous wounds that not received laser therapy; NDI: non-diabetic rats with cutaneous wounds that received laser therapy; DNI: diabetic rats with skin wounds who did not undergo laser therapy; DI: rats with diabetes insipidus and cutaneous wounds and received laser therapy...
September 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28929056/clinico-pathological-profile-of-deep-neck-space-infection-a-prospective-study
#12
Rumpa Das, Gorakh Nath, Anupam Mishra
Deep neck space infections (DNI) has been a common and serious disease, involving several spaces created by planes of greater and lesser resistance between the fascial layers of the neck. Infection of deep neck space has been dangerous due to its potential ease of spread from one space to other space, associated sepsis and upper airway obstruction. This prospective study was done in 45 patients of DNI over a period of 1 year. Patients with age of 1 month to 80 years of both the sexes were included. Patient's particular, clinical presentation and associated co-morbid conditions, physical examination, routine laboratory investigations and radiological investigations were analyzed...
September 2017: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/28918550/advance-care-planning-challenges-at-the-emergency-department-of-a-cancer-care-center
#13
Maria T Cruz-Carreras, Patrick Chaftari, Jayne Viets-Upchurch
INTRODUCTION: Code status discussions form an important part of advance care planning (ACP) as it enables physicians to respect the patient's wishes for end-of-life care. However, in some cases, code status discussions can be challenging causing the physician to go against the patient's wishes and the code of medical ethics. This is especially true in an emergency setting. In this paper, we will discuss three cases of advanced cancer patients, where code status discussions posed challenges to healthcare providers...
September 16, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28914272/a-randomized-controlled-trial-of-a-cpr-decision-support-video-for-patients-admitted-to-the-general-medicine-service
#14
Aimee M Merino, Ryan Greiner, Kristopher Hartwig
BACKGROUND: Patient preferences regarding cardiopulmonary resuscitation (CPR) are important, especially during hospitalization when a patient's health is changing. Yet many patients are not adequately informed or involved in the decision-making process. OBJECTIVE: We examined the effect of an informational video about CPR on hospitalized patients' code status choices. DESIGN: This was a prospective, randomized trial conducted at the Minneapolis Veterans Affairs Health Care System in Minnesota...
September 2017: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
https://www.readbyqxmd.com/read/28885386/a-delta-neutrophil-index-for-the-prediction-of-contrast-induced-nephropathy-in-patients-with-st-elevation-myocardial-infarction-followed-by-percutaneous-coronary-intervention
#15
Taeyoung Kong, Yoo Seok Park, Hye Sun Lee, Sinae Kim, Sehee Han, Claire H Eun, Jong Wook Lee, Je Sung You, Hyun Soo Chung, Incheol Park, Sung Phil Chung
PURPOSE: We assessed the usefulness of the delta neutrophil index (DNI), reflecting immature granulocytes, to stratify risk for developing contrast-induced nephropathy (CIN) in patients with ST-elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (PCI) in a clinical setting. METHODS: This study retrospectively analyzed prospective data of eligible adult patients admitted to the ED with STEMI followed by PCI. We determined DNI at multiple time points and analyzed the development of CIN and in-hospital mortality according to CIN incidence...
September 6, 2017: Shock
https://www.readbyqxmd.com/read/28827988/appraisal-of-different-ultrasonography-indices-in-patients-with-carotid-artery-atherosclerosis
#16
Mehravar Rafati, Elham Havaee, Hassan Moladoust, Mohammadreza Sehhati
In this study a semi-automated image-processing based method was designed in which the parameters such as intima-media thickness (IMT), resistive index (RI), pulsatility index (PI), dicrotic notch index (DNI), and mean wavelet entropy (MWE) were evaluated in B-mode and Doppler ultrasound in patients presenting with carotid artery atherosclerosis. In a cross-sectional design, 144 men were divided into four groups of control, mild, moderate and severe stenosis subjects. In all individuals, far wall IMT, RI, PI, DNI, and MWE of the left common carotid artery (CCA) were extracted using the proposed method...
2017: EXCLI Journal
https://www.readbyqxmd.com/read/28794144/nasal-high-flow-therapy-a-novel-treatment-rather-than-a-more-expensive-oxygen-device
#17
REVIEW
Eleni Ischaki, Ioannis Pantazopoulos, Spyros Zakynthinos
Nasal high flow is a promising novel oxygen delivery device, whose mechanisms of action offer some beneficial effects over conventional oxygen systems. The administration of a high flow of heated and humidified gas mixture promotes higher and more stable inspiratory oxygen fraction values, decreases anatomical dead space and generates a positive airway pressure that can reduce the work of breathing and enhance patient comfort and tolerance. Nasal high flow has been used as a prophylactic tool or as a treatment device mostly in patients with acute hypoxaemic respiratory failure, with the majority of studies showing positive results...
September 30, 2017: European Respiratory Review: An Official Journal of the European Respiratory Society
https://www.readbyqxmd.com/read/28780666/comparison-of-intubation-and-tracheotomy-in-patients-with-deep-neck-infection
#18
Laura Tapiovaara, Leif Bäck, Katri Aro
Possible airway compromise further complicates treatment of deep neck infections (DNI). Airway management is crucial, but factors affecting the method of choice are unclear. We retrospectively evaluated adult DNIs in a single tertiary center covering 10 years, with special attention on airway management. Patient data were retrieved from electronic data files from 2007 to 2016, and included adult patients with DNI operated through the neck. Of the 202 patients, 127 (63%) were male, with a median age of 47 years...
October 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28763506/the-delta-neutrophil-index-is-a-prognostic-factor-for-postoperative-mortality-in-patients-with-sepsis-caused-by-peritonitis
#19
Jong Wan Kim, Jun Ho Park, Doo Jin Kim, Won Hyuk Choi, Jin Cheol Cheong, Jeong Yeon Kim
INTRODUCTION: The delta neutrophil index (DNI) represents the fraction of circulating immature granulocytes and is a marker of infection and sepsis. Our objective was to evaluate the usefulness of DNI for predicting in-hospital mortality within 30 days after surgery in patients with sepsis caused by peritonitis by means of comparing DNI, white blood cell (WBC) count, neutrophil percentage, and C-reactive protein (CRP) before and after surgery. MATERIALS AND METHODS: We performed a retrospective analysis of demographic, clinical, and laboratory data...
2017: PloS One
https://www.readbyqxmd.com/read/28754440/to-intubate-or-not-to-intubate-emergency-medicine-physicians-perspective-on-intubating-critically-ill-terminal-cancer-patients
#20
Kenneth Kim, Bharath Chakravarthy, Craig Anderson, Solomon Liao
CONTEXT: Emergency physicians (EPs) often need to make a decision whether or not to intubate a terminal cancer patient. OBJECTIVE: The objective of this study was to explore EPs' attitudes about intubating critically ill, terminal cancer patients. METHODS: Fifty EPs at three emergency departments (one university based, one community, and one Health Maintenance Organization) in Southern California participated in an anonymous survey that presented a hypothetical case of an end-stage lung cancer patient in pending respiratory failure...
November 2017: Journal of Pain and Symptom Management
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