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https://www.readbyqxmd.com/read/28819939/serum-levels-of-soluble-interleukin-2-receptor-in-association-with-oxidative-stress-index-in-patients-with-different-types-of-hpv
#1
Cenk Nayki, Murat Gunay, Mehmet Kulhan, Umit Nayki, Murat Cankaya, Nur Gozde Kulhan
OBJECTIVES: The aim of this paper is to determine the oxidative-antioxidative status and levels of soluble interleukin-2 recep-tor (sIL-2R) in serum of patients with different types of HPV infections and to compare it with patients who are negative for HPV. MATERIAL AND METHODS: A total of 80 women were divided into three groups as follows: Group 1 consisted of 25 women who were positive for HPV types 16 or 18; Group 2 consisted of 25 women who were positive for other types of HPV includ-ing type 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 or 68; Group 3 consisted of 30 patients who were negative for HPV as a control group...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28814935/knowledge-and-attitude-of-dental-students-towards-hiv-aids-patients-in-melaka-malaysia
#2
Vijendra Pal Singh, Izni Syazana Osman, Nur Amanina Rahmat, Nur Ashikin Abu Bakar, Nurul Fathin Natasha Abdul Razak, Sowmya Nettem
BACKGROUND: Cross contamination of HIV is a real threat today. Dental treatment often includes direct contact with a patient's blood and saliva, therefore dental professionals can be easily exposed to HIV microorganisms. Hence, it is essential to gain insight into dental students' knowledge and attitude towards HIV patients. METHOD: A cross-sectional survey of 186 clinical year dental students (year 3, 4 and 5) in the 2015-2016 academic session at the Faculty of Dentistry, Melaka-Manipal Medical College (MMMC), Manipal University, Melaka volunteered to participate in the study...
May 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28813645/lat-is-essential-for-the-mast-cell-stabilising-effect-of-thga-in-ige-mediated-mast-cell-activation
#3
Ji Wei Tan, Daud Ahmad Israf, Nur Fariesha Md Hashim, Yoke Kqueen Cheah, Hanis Hazeera Harith, Khozirah Shaari, Chau Ling Tham
Mast cells play a central role in the pathogenesis of allergic reaction. Activation of mast cells by antigens is strictly dependent on the influx of extracellular calcium that involves a complex interaction between signalling molecules located within the cells. We have previously reported that tHGA, an active compound originally isolated from a local shrub known as Melicope ptelefolia, prevented IgE-mediated mast cell activation and passive systemic anaphylaxis by suppressing the release of interleukin-4 (IL-4) and tumour necrosis factor (TNF)-α from activated rat basophilic leukaemia (RBL)-2H3 cells...
August 13, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28813631/rapid-and-targeted-introgression-of-fgr-gene-through-marker-assisted-backcrossing-in-rice-oryza-sativa-l
#4
Acga Cheng, Ismanizan Ismail, Mohamad Osman, Habibuddin Hashim, Nur Samahah Mohd Zainual
While it is crucial for developing countries like Malaysia to achieve self-sufficiency in rice (Oryza sativa L.), it is equally critical to be able to produce high-quality rice, specifically fragrant rice, which demands are often met through importation. The present study was aimed at developing high-yielding fragrant rice, in a timely and cost-effective manner. A marker-assisted backcross (MABC) approach was optimised to introgress the fragrance gene (fgr) into two high-yielding Malaysian varieties; MR84 and MR219, within two years utilising less than fifty molecular markers...
August 16, 2017: Genome Génome / Conseil National de Recherches Canada
https://www.readbyqxmd.com/read/28811928/hepatocellular-carcinoma-with-disseminated-skeletal-muscle-metastasis
#5
Ezamin Abdul Rahim, Mohamad Sf Noh, Nur A Ngah, Mohamad S Suraini, Mubarak M Yusof
Hepatocellular carcinoma (HCC) is the commonest primary tumor of the liver and carries a poor prognosis when diagnosed late or left untreated. Treatment relies heavily on the stage of the tumor when diagnosed. Extrahepatic metastasis is known to occur; these are mainly reported via autopsy studies or isolated case reports. Knowledge of extrahepatic metastasis is crucial in order to avoid unnecessary surgery. We report a rare case of a patient at our center, diagnosed to have HCC, who underwent treatment successfully, only to come back with extrahepatic metastasis to the skeletal muscles...
July 2017: Acta Radiologica Open
https://www.readbyqxmd.com/read/28808448/relevance-of-the-nr4a-sub-family-of-nuclear-orphan-receptors-in-trophoblastic-bewo-cell-differentiation
#6
Sudha Saryu Malhotra, Satish Kumar Gupta
Nur-77, a member of the NR4A sub-family of nuclear orphan receptors, is downregulated in the placentae of pre-eclamptic women. Here, we investigate the relevance of Nor-1, Nurr-1 and Nur-77 in trophoblastic cell differentiation. Their transcript levels were found to be significantly upregulated in BeWo cells treated with forskolin. The maximum increase was observed after 2 h, with a second peak in the expression levels after 48 h. The expression of NR4A sub-family members was also found to be upregulated in BeWo cells after treatment with hCG and GnRH...
2017: Cellular & Molecular Biology Letters
https://www.readbyqxmd.com/read/28807573/axially-substituted-silicon-iv-phthalocyanine-and-its-quaternized-derivative-as-photosensitizers-towards-tumor-cells-and-bacterial-pathogens
#7
İpek Ömeroğlu, Esra Nur Kaya, Meltem Göksel, Vesselin Kussovski, Vanya Mantareva, Mahmut Durmuş
Axially di-(alpha,alpha-diphenyl-4-pyridylmethoxy) silicon(IV) phthalocyanine (3) and its quaternized derivative (3Q) were synthesized and tested as photosensitizers against tumor and bacterial cells. These new phthalocyanines were characterized by elemental analysis, and different spectroscopic methods such as FT-IR, UV-Vis, MALDI-TOF and (1)H NMR. The photophysical properties such as absorption and fluorescence, and the photochemical properties such as singlet oxygen generation of both phthalocyanines were investigated in solutions...
August 1, 2017: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/28804856/toxic-effects-of-copper-on-liver-and-cholinesterase-of-clarias-gariepinus
#8
Siti Nadzirah Padrilah, Siti Aqlima Ahmad, Nur Adeela Yasid, Mohd Khalizan Sabullah, Hassan Mohd Daud, Ariff Khalid, Mohd Yunus Shukor
The release of pollutants, especially heavy metals, into the aquatic environment is known to have detrimental effects on such an environment and on living organisms including humans when those pollutants are allowed to enter the food chain. The aim of this study is to analyse the damage to Clarias gariepinus' liver caused by exposure to different concentrations of copper. In the present study, samples of C. gariepinus were exposed to sub-lethal copper sulphate (CuSO4) concentrations (from 0.2 to 20.0 mg/L) for 96 h...
August 13, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28804586/health-related-quality-of-life-and-associated-factors-among-undergraduate-university-students
#9
Naim Nur, Ahmet Kıbık, Esma Kılıç, Haldun Sümer
OBJECTIVES: The aims of this study were to explore factors associated with health-related quality of life (HRQOL) among students of Cumhuriyet University, Turkey. METHODS: This cross-sectional study involved 1751 undergraduate students. HRQOL was measured using the Turkish version of 36-Item Short Form Health Survey questionnaire. We looked at the effect of sociodemographic characteristics (e.g., gender, age, drinking, and smoking) on the individual HRQOL domains...
July 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28803348/effect-of-small-proportion-of-butanol-additive-on-the-performance-emission-and-combustion-of-australian-native-first-and-second-generation-biodiesel-in-a-diesel-engine
#10
Md Mofijur Rahman, Mohammad Golam Rasul, Nur Md Sayeed Hassan, Abul Kalam Azad, Md Nasir Uddin
This paper aims to investigate the effect of the addition of 5% alcohol (butanol) with biodiesel-diesel blends on the performance, emissions, and combustion of a naturally aspirated four stroke multi-cylinder diesel engine at different engine speeds (1200 to 2400 rpm) under full load conditions. Three types of local Australian biodiesel, namely macadamia biodiesel (MB), rice bran biodiesel (RB), and waste cooking oil biodiesel (WCB), were used for this study, and the data was compared with results for conventional diesel fuel (B0)...
August 12, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28803192/early-life-secondhand-smoke-exposure-assessed-by-hair-nicotine-biomarker-may-reduce-children-s-neurodevelopment-at-2years-of-age
#11
Nur Nadia Mohamed, See Ling Loy, Poh Ying Lim, Abdullah Al Mamun, Hamid Jan Jan Mohamed
Exposure to secondhand smoke (SHS) can affect fetal brain development as well as subsequent neurodevelopment. This study aimed to determine the association between prenatal and postnatal SHS exposure with children's neurodevelopment at 2years of age. Among 107 mother-child pairs from a Malaysia prospective cohort, prenatal and postnatal SHS exposure was determined based on maternal and child hair nicotine concentrations. Multiple linear regressions were used to determine the association between prenatal and postnatal levels of nicotine in maternal and children's' hair with children's neurodevelopment...
August 10, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28802285/a-nutrition-care-process-knowledge-attitudes-practices-and-perceived-barriers-questionnaire
#12
Zaini Bahari, Zuriati Ibrahim, Siti Nur Asyura Adznam, Barakatun Nisak Mohd Yusof
BACKGROUND AND OBJECTIVES: Assessment of the nutrition care process (NCP) knowledge, attitudes, practices, and perceived barriers (KAPB) of dietetics practitioners is imperative before NCP is implemented completely in dietetics practice. No questionnaire assessing NCP KAPB has been developed and validated. Hence, we developed an NCP KAPB questionnaire called the KAPB-NCP and established its content validity. METHODS AND STUDY DESIGN: A total of 116 items associated with sociodemographic characteristics (7 items), professional development (3 items), organisational culture's support for the NCP (2 items), knowledge (27 items), attitudes (39 items), practices (20 items), and perceived barriers to implementing the NCP (14 items) were generated for potential inclusion in the KAPB-NCP questionnaire...
2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28801887/degradation-of-5-5-diphenylhydantoin-by-chlorination-and-uv-chlorination-kinetics-transformation-by-products-and-toxicity-assessment
#13
Nur Adawiyah Mansor, Kheng Soo Tay
This study investigated the reaction kinetics and mechanism of the degradation of 5,5-diphenylhydantoin (DPH) during conventional chlorination and UV/chlorination. DPH is one of the antiepileptic drugs, which has frequently been detected in the aquatic environment. For chlorination, the second-order rate constant for the reaction between DPH and free active chlorine (FAC) was determined at pH 5 to 8. At pH 6 to 8, the efficiency of chlorination in the removal of DPH was found to be dominated by the reaction involving hypochlorous acid (HOCl)...
August 11, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28798782/evaluation-of-local-carotid-stiffness-and-inflammatory-biomarkers-in-stable-angina-pectoris
#14
Abdullah Nabi Aslan, Ayşe Nur Özcan, Hüseyin Ayhan, Serkan Sivri, Filiz Çelebi, Karabekir Ercan, Tahir Durmaz
INTRODUCTION: Arterial stiffness (AS) is a well-accepted and reliable predictor of atherosclerotic diseases. Inflammation plays an important role in the development of AS. AIM: To evaluate local carotid stiffness (CS) together with fibrinogen and high-sensitivity C-reactive protein (hsCRP) levels in stable angina pectoris (SAP) patients. MATERIAL AND METHODS: The study consisted of 353 consecutive patients with SAP. All underwent coronary angiography (CAG) after the evaluation of local CS parameters and carotid intima-media thickness (IMT) from both common carotid arteries by a real-time echo-tracking system...
2017: Postępy W Kardiologii Interwencyjnej, Advances in Interventional Cardiology
https://www.readbyqxmd.com/read/28797998/the-effect-of-dose-volume-parameters-on-central-nervous-system-relapse-in-pediatric-patients-with-acute-leukemia-receiving-prophylactic-cranial-irradiation
#15
Zeliha Guzeloz, Ayse Nur Demiral, Fatma Eren, Mehmet Adigul, Ahmet Ergin Capar, Handan Cakmakci, Sebnem Yilmaz, Ozlem Tufekci, Hale Oren, Riza Çetingoz
AIM OF THE STUDY: To investigate the effects of dosevolume parameters of brain parenchyma, optic nerves (ONs) and cribriform plate (CP), which were determined on central nervous system (CNS) control in pediatric leukemia patients who have undergone prophylactic cranial irradiation (PCI) at our department. PATIENTS AND METHODS: In the current study, the records of 14 patients were examined retrospectively. Along with the minimum and maximum doses for brain and CP, D95% (minimal dose received by the 95% volume of a structure) and V95% (percent volume of target receiving 95% of prescribed dose) could be obtained from the dose-volume histogram...
May 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28797747/metal-composite-adhesion-based-on-diazonium-chemistry
#16
Yara Oweis, Omar Alageel, Paige Kozak, Mohamed-Nur Abdallah, Jean-Marc Retrouvey, Marta Cerruti, Faleh Tamimi
OBJECTIVE: Composite resins do not adhere well to dental alloys. This weak bond can result in failure at the composite-metal interface in fixed dental prostheses and orthodontic brackets. The aim of this study was to develop a new adhesive, based on diazonium chemistry, to facilitate chemical bonding between dental alloys and composite resin. METHODS: Samples of two types of dental alloys, stainless steel and cobalt chromium were primed with a diazonium layer in order to create a surface coating favorable for composite adhesion...
August 7, 2017: Dental Materials: Official Publication of the Academy of Dental Materials
https://www.readbyqxmd.com/read/28795251/5-fluorouracil-induced-mitochondrial-oxidative-cytotoxicity-and-apoptosis-are-increased-in-mcf-7-human-breast-cancer-cells-by-trpv1-channel-activation-but-not-hypericum-perforatum-treatment
#17
Haci Ahmet Deveci, Mustafa Nazıroğlu, Gökhan Nur
5-Fluorouracil (5-FU) is a widely used chemotherapy agent for breast cancer, although drug resistance is a critical issue regarding the use of this agent in the disease. Calcium signaling is a well-known main cause of proliferation and apoptosis in breast cancer cells. Although previous studies have implicated TRPV1 inhibitor, anticancer, and apoptotic roles of Hypericum perforatum (HPer) in several cells, the synergistic inhibition effects of HPer and 5-FU in cancer and the stimulation of ongoing apoptosis have not yet been clarified in MCF-7 cells...
August 9, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28793998/the-clinical-and-mutational-spectrum-of-turkish-patients-with-cystinosis
#18
Rezan Topaloglu, Bora Gulhan, Mihriban İnözü, Nur Canpolat, Alev Yilmaz, Aytül Noyan, İsmail Dursun, İbrahim Gökçe, Metin Kaya Gürgöze, Nurver Akinci, Esra Baskin, Erkin Serdaroğlu, Beltinge Demircioğlu Kiliç, Selçuk Yüksel, Duygu Övünç Hacihamdioğlu, Emine Korkmaz, Mutlu Hayran, Fatih Ozaltin
BACKGROUND AND OBJECTIVES: Infantile nephropathic cystinosis is a severe disease that occurs due to mutations in the cystinosis gene, and it is characterized by progressive dysfunction of multiple organs; >100 cystinosis gene mutations have been identified in multiple populations. Our study aimed to identify the clinical characteristics and spectrum of cystinosis gene mutations in Turkish pediatric patients with cystinosis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We identified the clinical characteristics and spectrum of cystinosis gene mutations in Turkish patients with cystinosis in a multicenter registry that was established for data collection...
August 9, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28792192/early-term-effect-of-ureterorenoscopy-urs-on-the-kidney-research-measuring-ngal-kim-1-fabp-and-cys-c-levels-in-urine
#19
Erdal Benli, Sema Nur Ayyildiz, Selma Cirrik, Tevfik Noyan, Ali Ayyildiz, Abdullah Cirakoglu
AIM: URS is a very commonly used procedure for treatment of ureter stones. Increased hydrostatic pressure in the collecting system linked to fluids used during the procedure may cause harmful effects on the kidney. The aim of this study is to determine whether the URS procedure has a negative effect on the kidney by investigating NGAL, KIM-1, FABP and Cys C levels in urine. MATERIAL AND METHODS: This study included 30 patients undergoing ureterorenoscopy (URS) for ureter stones...
August 8, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28791524/histological-analysis-of-anti-cancer-drug-loaded-targeted-mn-zns-quantum-dots-in-metastatic-lesions-of-4t1-challenged-mice
#20
Ibrahim Birma Bwatanglang, Faruq Mohammad, Nor Azah Yusof, Nurul Elyani Mohammed, Nadiah Abu, Noorjahan Banu Alitheen, Jaafar Abdullah, Mohd Zubir Hussein, Yusuf Abba, Noraini Nordin, Nur Rizi Zamberi
5-Fluororaucil (5-FU) as anti-cancer drug was reported to induce thymidine synthase (TS) overexpression and cancer cell resistance. To improve its therapeutic efficacy and selective targeting, here we developed a targeted delivery system mediated by the active ligand-folate receptor chemistry to deliver the 5-FU drug selectively into the tumor microenvironment. The preparation was achieved by exploring chitosan (CS)-biopolymer based system with folic acid (FA)-conjugation. The 5-FU@FACS-Mn:ZnS quantum dots (QDs) based on the histological assessment conducted in the 4T1 challenged mice showed an improved tumor remission in the liver, spleen and lungs...
August 8, 2017: Journal of Materials Science. Materials in Medicine
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