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https://www.readbyqxmd.com/read/29703025/association-between-perioperative-hypothermia-and-patient-outcomes-after-thoracic-surgery-a-single-center-retrospective-analysis
#1
Alexander Emmert, Gereon Gries, Saskia Wand, Judith Buentzel, Anselm Bräuer, Michael Quintel, Ivo F Brandes
Hypothermia due to anaesthetic-induced impairment of thermoregulatory control and exposure to a cool environment is common in surgical patients. Peripheral vasodilation due to neuroaxial blockade may aggravate hypothermia. There is few data on perioperative hypothermia in patients undergoing thoracic surgery under combined general and regional anesthesia. We reviewed all thoracic surgical patients between 2006 and 2011 to determine the incidence and extent of hypothermia with or without an epidural anesthesia and evaluated its effect...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29696821/a-simple-antegrade-perfusion-method-for-isolating-viable-single-cardiomyocytes-from-neonatal-to-aged-mice
#2
Mariko Omatsu-Kanbe, Kengo Yoshioka, Ryo Fukunaga, Hironori Sagawa, Hiroshi Matsuura
The aim of this study was to establish a simple and reproducible antegrade perfusion method for isolating single viable mouse heart cells and to determine the standard practical protocols that are appropriate for mice of various ages. Antegrade perfusion was performed by injecting perfusate from near the apex of the left ventricle of the excised heart, the aorta of which was clamped, using an infusion pump. This could thoroughly perfuse the myocardium through the coronary circulation. All procedures were carried out on a prewarmed heater mat under a microscope, which allows for the processes of injection and perfusion to be monitored...
May 2018: Physiological Reports
https://www.readbyqxmd.com/read/29608373/cold-susceptibility-of-digit-stumps-resulting-from-amputation-after-freezing-cold-injury-in-elite-alpinists
#3
Jurij Gorjanc, Shawnda A Morrison, Rok Blagus, Igor B Mekjavic
Gorjanc, Jurij, Shawnda A. Morrison, Rok Blagus, and Igor B. Mekjavic. Cold susceptibility of digit stumps resulting from amputation after freezing cold injury in elite alpinists. High Alt Med Biol. 16: 000-000, 2018. AIM: The aim of the study was to assess whether previous freezing cold injury in fingers and/or toes might predispose alpinists to greater risk of further freezing cold injury, primarily due to a greater vasoconstrictor response to cold, resulting in a lower perfusion, reflected in lower skin temperature...
April 2, 2018: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/29513233/effect-of-composite-warming-on-shear-bond-strength
#4
Thomas F McDaniel, Thomas W Sigrist, Gary M Johnson
Several manufacturers produce devices designed to warm composite resins used in restorative dentistry. Previous investigators have examined the effects of heating composite restorative resins prior to placement and polymerization. Heating has been reported to reduce viscosity, improve ease of placement, enhance monomer conversion, and reduce microleakage. The aim of the present study was to compare shear bond strengths of room temperature (22°C) and prewarmed (54°C) restorative composite resin. Extracted bovine mandibular incisors were sectioned sagittally and embedded in acrylic cylinders...
March 2018: General Dentistry
https://www.readbyqxmd.com/read/29408669/effect-of-diesel-exhaust-generated-by-a-city-bus-engine-on-stress-responses-and-innate-immunity-in-primary-bronchial-epithelial-cell-cultures
#5
M C Zarcone, E Duistermaat, M J Alblas, A van Schadewijk, D K Ninaber, V Clarijs, M M Moerman, D Vaessen, P S Hiemstra, I M Kooter
Harmful effects of diesel emissions can be investigated via exposures of human epithelial cells, but most of previous studies have largely focused on the use of diesel particles or emission sources that are poorly representative of engines used in current traffic. We studied the cellular response of primary bronchial epithelial cells (PBECs) at the air-liquid interface (ALI) to the exposure to whole diesel exhaust (DE) generated by a Euro V bus engine, followed by treatment with UV-inactivated non-typeable Haemophilus influenzae (NTHi) bacteria to mimic microbial exposure...
April 2018: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/29159490/-prewarming-according-to-the-awmf-s3-guidelines-on-preventing-inadvertant-perioperative-hypothermia-2014-retrospective-analysis-of-7786-patients
#6
R Grote, A J Wetz, A Bräuer, M Menzel
BACKGROUND: Inadvertent perioperative hypothermia, which is defined as a core body temperature of less than 36.0 °C, can have serious consequences in surgery patients. These include cardiac complications, increased blood loss, wound infections and postoperative shivering; therefore, the scientific evidence that inadvertent perioperative hypothermia should be avoided is undisputed and several national guidelines have been published summarizing the scientific evidence and recommending specific procedures...
January 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/28938977/efficacy-of-prewarming-with-a-self-warming-blanket-for-the-prevention-of-unintended-perioperative-hypothermia-in-patients-undergoing-hip-or-knee-arthroplasty
#7
Charlotte Rosenkilde, Marianne Vamosi, Jørgen T Lauridsen, Dorthe Hasfeldt
PURPOSE: Unintended perioperative hypothermia (UPH) is a common and serious complication for patients undergoing anesthesia. The purpose of this study was to identify the incidence of UPH and evaluate the efficacy of a self-warming blanket on the drop in core temperature and risk of UPH in patients undergoing hip or knee arthroplasty. DESIGN: A case-control study was used. METHODS: Sixty patients were included. Thirty patients received prewarming with a self-warming blanket and forced-air warming intraoperatively; thirty patients received only forced-air warming intraoperatively...
October 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28743152/-prevention-of-perioperative-hypothermia-guidelines-for-daily-clinical-practice
#8
Timo Iden, Jan Höcker
Inadvertent perioperative hypothermia (body core temperature < 36 °C) is a serious complication leading to increased rates of wound infection, higher blood loss associated with increased transfusion requirements as well as patient dissatisfaction among others. Body core temperature is a vital parameter and needs constant monitoring just like heart rate, blood pressure and arterial oxygen saturation. Patient-, anesthesia-, surgery- and environment-related risk factors were identified for occurring perioperative hypothermia...
July 2017: Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie: AINS
https://www.readbyqxmd.com/read/28628137/-antagonistic-effect-of-quercetin-on-pm2-5-toxicity-in-the-rat-s-embryonic-development-in-vitro
#9
A Q Fan, J Q Feng, W Liu, M J Zhang, T Liu, Y L Zhou, Y J Xu
OBJECTIVE: To explore the antagonistic effect of quercetin on fine particulate matter (PM2.5)-induced embryonic developmental toxicity in vitro. METHODS: PM2.5 was collected on glass fiber filters by PM2.5 samplers during the heating period of Dec. 2015 to Mar. 2016 in an area of Haidian District, Beijing City. The sampled filters were cut into 1 cm×3 cm pieces followed by sonication. The PM2.5 suspension was filtered into a 10 cm glass dish through 8 layers of sterile carbasus and stored at -80 °C until freeze drying...
June 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28527547/the-optimal-time-and-method-for-surgical-prewarming-a-comprehensive-review-of-the-literature
#10
REVIEW
Lauren Connelly, Emily Cramer, Quinn DeMott, Jennifer Piperno, Bethany Coyne, Clara Winfield, Michael Swanberg
PURPOSE: Inadvertent hypothermia is a common problem in the operating room. This can contribute to many unfavorable outcomes --rising costs, increased complications, and higher morbidity rates. DESIGN: This review determined the optimal method and time to prewarm a surgical patient to prevent perioperative hypothermia. METHODS: CINAHL and PubMed were searched. Fourteen articles were ultimately included in this review. FINDINGS: Based on the literature reviewed, it was suggested that forced-air warming was most effective in preventing perioperative hypothermia...
June 2017: Journal of Perianesthesia Nursing: Official Journal of the American Society of PeriAnesthesia Nurses
https://www.readbyqxmd.com/read/28353593/warming-infusion-improves-perioperative-outcomes-of-elderly-patients-who-underwent-bilateral-hip-replacement
#11
RANDOMIZED CONTROLLED TRIAL
He Ma, Bingjie Lai, Shanshan Dong, Xinyu Li, Yunfeng Cui, Qianchuang Sun, Wenhua Liu, Wei Jiang, Feng Xu, Hui Lv, Hongyu Han, Zhenxiang Pan
BACKGROUND: This prospective, randomized, and controlled study was performed to determine the benefits of prewarmed infusion in elderly patients who underwent bilateral hip replacement. METHODS: Between September 2015 and April 2016, elderly patients who underwent bilateral hips replacement that met the inclusion and exclusion criteria were included in this study. After inclusion, patients were randomized into one of the study groups: in the control group, patients received an infusion of fluid kept at room temperature (22-23°C); in the warming infusion group, patients received an infusion of fluid warmed using an infusion fluid heating apparatus (35°C)...
March 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28121211/heated-intravenous-fluids-alone-fail-to-prevent-hypothermia-in-cats-under-general-anaesthesia
#12
RANDOMIZED CONTROLLED TRIAL
Geraldine Jourdan, Caroline Didier, Erwan Chotard, Sandra Jacques, Patrick Verwaerde
Objectives The objective was to evaluate the clinical efficiacy of a constant rate infusion of heated fluid as the sole means of preventing intraoperative hypothermia in cats. Methods This randomised, prospective, clinical study was conducted at a university teaching veterinary hospital. Female cats (American Society of Anesthesiologists [ASA] grade I) undergoing elective surgery by laparotomy under general anaesthesia (acepromazine 0.05 mg/kg SC; morphine 0.2 mg/kg IV; propofol IV titrated, isoflurane 2% in 100% oxygen) were randomised in two groups...
December 2017: Journal of Feline Medicine and Surgery
https://www.readbyqxmd.com/read/28070632/-prevention-of-perioperative-hypothermia-implementation-of-the-s3-guideline
#13
E-P Horn, E Klar, J Höcker, A Bräuer, B Bein, H Wulf, A Torossian
To improve perioperative quality and patient safety, the German S3 guideline should be consistently implemented to avoid perioperative hypothermia. Perioperative normothermia is a quality indicator and should be achieved by anesthesiologists and surgeons. To detect hypothermia early during the perioperative process, measuring body temperature should be started 1-2 h preoperatively. Patients should be actively warmed for 20-30 min before starting anesthesia. Prewarming is most effective and should be included in the preoperative process...
May 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/27974591/the-effect-of-formulation-process-and-method-variables-on-the-reconstitution-time-in-dual-chamber-syringes
#14
Tobias Werk, Imke S Ludwig, Hanns-Christian Mahler, Joerg Luemkemann, Joerg Huwyler, Mathias Hafner
Reconstitution time of dried products is influenced by various factors including formulation, process, and reconstitution method itself. This manuscript describes factors affecting reconstitution in a dual chamber syringe using highly concentrated human monoclonal antibody and bovine serum albumin model formulations. Freezing and drying conditions had only minor impact on the reconstitution time, whereas the primary container and thus the geometry of the lyophilization cake played a major role. Prewarmed diluent and agitation decreased reconstitution time...
November 2016: PDA Journal of Pharmaceutical Science and Technology
https://www.readbyqxmd.com/read/27785761/using-physiological-monitoring-data-for-performance-feedback-an-initiative-using-thermoregulation-metrics
#15
Matthias Görges, Nicholas C West, Simon D Whyte
BACKGROUND: Feedback of performance data can improve professional practice and outcomes. Vital signs are not routinely used for quality improvement because of their limited access. Intraoperative hypothermia has been associated with deleterious effects, including surgical site infections and bleeding. We speculated that providing feedback could help keep temperature monitoring and management a priority in the anesthesiologist's mind, thereby improving perioperative temperature management...
March 2017: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/27749346/intravenous-air-the-partially-invisible-phenomenon
#16
Christopher Varga, Isaac Luria, Nikolaus Gravenstein
BACKGROUND: Air injection is carefully avoided during IV solution administration; however, ambient air is dissolved in all liquids used for intravenous (IV) therapy. A portion of this gas will come out of solution in the form of bubbles as the solution is warmed to body temperature in a fluid warming system and/or within the body. We sought to quantify the proportion of the gas theoretically dissolved in room temperature crystalloid and 4°C blood products that comes out of solution in the IV tubing on warming to 37°C...
November 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27687449/active-perioperative-patient-warming-using-a-self-warming-blanket-barrier-easywarm-is-superior-to-passive-thermal-insulation-a-multinational-multicenter-randomized-trial
#17
RANDOMIZED CONTROLLED TRIAL
Alexander Torossian, Elke Van Gerven, Karin Geertsen, Bengt Horn, Marc Van de Velde, Johan Raeder
STUDY OBJECTIVE: Incidence of inadvertent perioperative hypothermia is still high; therefore, present guidelines advocate "prewarming" for its prevention. Prewarming means preoperative patient skin warming, which minimizes redistribution hypothermia caused by induction of anesthesia. In this study, we compared the new self-warming BARRIER EasyWarm blanket with passive thermal insulation regarding mean perioperative patient core body temperature. DESIGN: Multinational, multicenter randomized prospective open-label controlled trial...
November 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27555196/a-randomized-trial-of-prewarming-on-patient-satisfaction-and-thermal-comfort-in-outpatient-surgery
#18
RANDOMIZED CONTROLLED TRIAL
Zohaib Akhtar, Brian D Hesler, Alexa N Fiffick, Edward J Mascha, Daniel I Sessler, Andrea Kurz, Sabry Ayad, Leif Saager
STUDY OBJECTIVE: To test the primary hypothesis that forced-air prewarming improves patient satisfaction after outpatient surgery and to evaluate the effect on core temperature and thermal comfort. DESIGN: Prospective randomized controlled trial. SETTING: Preoperative area, operating room, and postanesthesia care unit. PATIENTS: A total of 115 patients aged 18 to 75 years with American Society of Anesthesiologists status <4 and body mass index of 15 to 36kg/m(2) who were undergoing outpatient surgery (duration <4 hours)...
September 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27546475/reflective-blankets-are-as-effective-as-forced-air-warmers-in-maintaining-patient-normothermia-during-hip-and-knee-arthroplasty-surgery
#19
RANDOMIZED CONTROLLED TRIAL
Clarissa Tjoakarfa, Vikram David, Atlas Ko, Raphael Hau
BACKGROUND: The use of forced air warming devices in the operating room has been shown to cause disruption of laminar airflow and a potential for increase in surgical site contamination. In contrast, conductive warming devices such as reflective blankets do not disrupt airflow and therefore have no potential for this increase in surgical site infection. However, some studies have shown them to be inferior to forced air warming devices in maintaining normothermia. We tested the hypothesis that the use of reflective blankets is as effective as forced air warming devices in maintaining intraoperative normothermia after adequate prewarming...
February 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/27442052/effect-of-prewarming-during-induction-of-anesthesia-on-microvascular-reactivity-in-patients-undergoing-off-pump-coronary-artery-bypass-surgery-a-randomized-clinical-trial
#20
RANDOMIZED CONTROLLED TRIAL
Youn Joung Cho, Seo Yun Lee, Tae Kyong Kim, Deok Man Hong, Yunseok Jeon
BACKGROUND: General anesthesia may induce inadvertent hypothermia and this may be related to perioperative cardiovascular complications. Microvascular reactivity, measured by the recovery slope during a vascular occlusion test, is decreased during surgery and is also related to postoperative clinical outcomes. We hypothesized that microvascular changes during surgery may be related to intraoperative hypothermia. To evaluate this, we conducted a randomized study in patients undergoing off-pump coronary artery bypass surgery, in which the effect of prewarming on microvascular reactivity was evaluated...
2016: PloS One
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