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Infectious disease in hospital

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https://www.readbyqxmd.com/read/29908018/adherence-to-antiretroviral-therapy-in-hiv-positive-male-intravenous-drug-users-in-pakistan
#1
Bakht Ali, Nighat Nisar, Faryal Nawab
Background: Human immunodeficiency virus (HIV) is fifth leading cause of mortality and disability among infectious diseases worldwide. HIV burden is increasing annually and compliance with antiretroviral therapy (ART) is low among intravenous drug users, especially in developing countries. Aim: To determine the adherence level to ART among HIV-positive intravenous drug users in Karachi Pakistan. Methods: A cross-sectional study was conducted in 2015...
June 10, 2018: Eastern Mediterranean Health Journal, la Revue de Santé de la Méditerranée Orientale
https://www.readbyqxmd.com/read/29905921/pediatric-inpatient-and-emergency-dermatology-consultations-a-5-year-retrospective-analysis
#2
Mariana Cruz-Manzano, Cristina N Brau-Javier, Sheila Valentín-Nogueras, Luz D Figueroa-Guzmán
OBJECTIVE: To characterize and analyze the inpatient and emergency pediatric dermatology consults in our academic hospital center. METHODS: We reviewed 485 consultations that were done by the University of Puerto Rico Department of Dermatology from July 2007 to June 2012. The date, patient age and gender, consulting service, presumptive diagnosis, final diagnosis, and diagnostic procedures performed were documented for each consult. RESULTS: The patients' ages ranged from newborn to 18 years; the 13 to 18 years age group was the most common (29%)...
June 2018: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29905559/-clinical-and-immunological-criteria-for-the-adverse-course-of-infectious-mononucleosis-in-children
#3
Ya Kolesnik, T Zharkova, O Rzhevskaya, T Kvaratskheliya, O Sorokina
The article presents the results of our own studies to determine the criteria for the adverse variants of the course of infectious mononucleosis (IM) in children. The study was conducted in the regional children's infectious clinical hospital in Kharkov. 161 children aged three to fifteen years were under observation with diagnosis of infectious moninucleosis. Out of 161 ill children, 140 (86.9%) had moderate severity of disease, and 21 (13.1%) had severe forms. All children were prescribed standard clinical and laboratory-instrumental examinations...
May 2018: Georgian Medical News
https://www.readbyqxmd.com/read/29901775/early-infectious-diseases-specialty-intervention-is-associated-with-shorter-hospital-stays-and-lower-readmission-rates-a-retrospective-cohort-study
#4
Steven Schmitt, Ann T MacIntyre, Susan C Bleasdale, J Trees Ritter, Sandra B Nelson, Elie F Berbari, Steven D Burdette, Angela Hewlett, Matthew Miles, Philip A Robinson, Javeed Siddiqui, Robin Trotman, Lawrence Martinelli, Gary Zeitlin, Andrés Rodriguez, Mark W Smith, Daniel P McQuillen
Background: Intervention by infectious diseases (ID) physicians improves outcomes for inpatients in Medicare, but patients with other insurance types could fare differently. We assessed whether ID involvement leads to better outcomes among privately insured patients under age 65 hospitalized with common infections. Methods: We performed a retrospective analysis of administrative claims data from community hospital and post-discharge ambulatory care. Patients were privately insured individuals under 65 years old with an acute-care stay in 2014 for selected infections, classed as having early (by day 3) or late (after day 3) ID intervention, or none...
June 13, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29900894/string-test-a-new-tool-for-tuberculosis-diagnosis-and-drug-resistance-detection-in-children
#5
Belén Rocío Imperiale, Cecilia Nieves, Belén Mancino, Myriam Sanjurjo, Silvina Tártara, Ángela Beatríz Di Giulio, Juan Carlos Palomino, Nora Susana Morcillo, Anandi Martin
Background: There is a critical need to improve the diagnostic accuracy of tuberculosis (TB) in children. Several techniques have been developed to improve the quality of sputum samples; however, these procedures are very unpleasant and invasive and require hospitalization and trained personnel. This study aims to explore the potential use of a new and noninvasive tool, "string test," for TB diagnosis in children and in adults not able to render sputum samples and at risk of developing multidrug-resistant TB (MDR-TB)...
April 2018: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/29898630/severe-plasmodium-falciparum-malaria-treated-with-investigational-artesunate-in-the-united-states
#6
Punit J Shah, Janice Koshy, Nichelle Everett, Engie Attia
PURPOSE: We describe here the case of a 40-year-old Nigerian male with severe Plasmodium falciparum malaria successfully treated with investigational intravenous (IV) artesunate. SUMMARY: A 40-year-old Nigerian male was admitted to the medical intensive care unit for the treatment of severe malaria. The patient presented with the classic malaria paroxysm and altered mental status and was in acute renal failure. A blood parasite, thick and thin smear was performed revealing positive ring forms on smear which are characteristic of Plasmodium falciparum, with an estimated parasitemia of 2%...
January 1, 2018: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29896329/detection-of-antimicrobial-susceptibility-and-integrons-among-extended-spectrum-%C3%AE-lactamase-producing-uropathogenic-escherichia-coli-isolates-in-southwestern-iran
#7
Hadi Sedigh Ebrahim-Saraie, Niloofar Zahedian Nezhad, Hamid Heidari, Ashkan Motamedifar, Mohammad Motamedifar
Objectives: Urinary tract infections (UTIs) are one of the most prevalent infectious diseases and can lead to a high rate of morbidity and mortality. The emergence of multiple-drug resistant strains, particularly extended-spectrum beta-lactamases (ESBLs) producing strains, has become a global healthcare concern. Our study sought to investigate the antimicrobial resistance pattern and presence of integrons and fimH determinants among uropathogenic Escherichia coli (UPEC) isolates obtained from hospitalized Iranian patients...
May 2018: Oman Medical Journal
https://www.readbyqxmd.com/read/29895320/disease-mentions-in-airport-and-hospital-geolocations-expose-dominance-of-news-events-for-disease-concerns
#8
Joana M Barros, Jim Duggan, Dietrich Rebholz-Schuhmann
BACKGROUND: In recent years, Twitter has been applied to monitor diseases through its facility to monitor users' comments and concerns in real-time. The analysis of tweets for disease mentions should reflect not only user specific concerns but also disease outbreaks. This requires the use of standard terminological resources and can be focused on selected geographic locations. In our study, we differentiate between hospital and airport locations to better distinguish disease outbreaks from background mentions of disease concerns...
June 12, 2018: Journal of Biomedical Semantics
https://www.readbyqxmd.com/read/29894472/utilization-of-fine-needle-aspiration-cytology-at-kamuzu-central-hospital
#9
Shiraz Khan, George Liomba, Nora E Rosenberg, Christopher Stanley, Cocxilly Kampani, Bal Mukunda Dhungel, Mina C Hosseinipour
BACKGROUND: Fine needle aspiration cytology (FNAC) has been widely accepted to be a safe, accurate, prompt and inexpensive procedure for diagnosis of both neoplastic and infectious diseases in adult and pediatric populations. Despite its value for diagnosis, FNAC is underutilized in resource limited countries. We reviewed the utilization of FNAC after it was introduced at Kamuzu Central Hospital (KCH). METHODS: A retrospective review of all FNAC performed at KCH laboratory during the period of January 2012 to July 2014 was conducted using an electronic database from KCH laboratory...
2018: PloS One
https://www.readbyqxmd.com/read/29893198/utilization-and-clinical-value-of-diagnostic-modalities-for-tuberculosis-in-a-high-hiv-prevalence-setting
#10
Stephanie Gati, Rhoda Chetty, Douglas Wilson, Jacqueline M Achkar
Human immunodeficiency virus (HIV) infection is a major risk factor for the development of active tuberculosis (TB), one of the deadliest infectious diseases globally. The high mortality associated with the disease can be reduced by early diagnosis and prompt antituberculous treatment initiation. Facilities in TB-endemic regions are increasing the use of nucleic acid amplification (e.g., GeneXpert), which provides rapid results but may have suboptimal sensitivity in HIV-associated TB. Our objective was to evaluate the current practices for TB diagnosis at Edendale Hospital, a large regional hospital in KwaZulu-Natal, South Africa-a TB-endemic region with high HIV prevalence...
June 11, 2018: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29889673/a-case-of-severe-pembrolizumab-induced-neutropenia
#11
Barbacki Ariane, Peter G Maliha, Marie Hudson, David Small
Immune checkpoint inhibitors have revolutionized cancer therapy. Given their mechanism of action, immune-related adverse events have been associated with their use. We present the first documented case of pembrolizumab-induced grade IV neutropenia. A 73-year-old women known for myositis, Crohn's disease, and hypothyroidism and diagnosed with PD-L1 positive stage IV pulmonary adenocarcinoma is treated with Pembrolizumab. She develops grade IV neutropenia 2 weeks after her second infusion. She is therefore hospitalized and treated initially with corticosteroids, granulocyte colony-stimulating factor, and intravenous immunoglobulins...
June 8, 2018: Anti-cancer Drugs
https://www.readbyqxmd.com/read/29888926/features-and-outcomes-of-immunoglobulin-therapy-in-patients-with-good-syndrome-at-thailand-s-largest-tertiary-referral-hospital
#12
Torpong Thongngarm, Adhiratha Boonyasiri, Panitan Pradubpongsa, Nattaporn Tesavibul, Tauangtham Anekpuritanang, Piyawut Kreetapirom, Mongkhon Sompornrattanaphan
BACKGROUND: Good syndrome (GS) is an adult-onset immunodeficiency characterized by coexisting thymoma and hypogammaglobulinemia. Clinical course after treatment with intravenous immunoglobulin (IVIg) has rarely been reported. OBJECTIVE: To investigate and report the clinical course and outcomes of GS patients after treatment with IVIg at Thailand's largest national tertiary referral hospital METHODS: This retrospective chart review included patients diagnosed with GS and treated with IVIg during the 1 January 2005 to 31 December 2015 study period...
June 11, 2018: Asian Pacific Journal of Allergy and Immunology
https://www.readbyqxmd.com/read/29886114/toxic-epidermal-necrolysis-data-from-the-celeste-multinational-registry-part-i-epidemiology-and-general-microbiological-characteristics
#13
B Lipový, J Holoubek, M Hanslianová, M Cvanová, L Klein, I Grossová, R Zajíček, P Bukovčan, J Koller, M Baran, P Lengyel, L Eimer, M Jandová, M Košťál, P Brychta
INTRODUCTION: Toxic epidermal necrolysis (TEN) is a rare, life-threatening autoimmune disease predominantly manifested in the skin and mucous membranes. Today, infectious complications have the dominant share in mortality of TEN patients. Due to the nature of the therapy and administration of immunosuppressive medications, a wide range of potentially pathogenic microorganisms, which cause infectious complications in different compartments in these patients, is not surprising. MATERIAL AND METHODOLOGY: This is a multicentric study, which included all patients with TEN hospitalized between 2000-2015 in specialized centres in the Czech Republic and Slovakia...
June 6, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29881224/infectious-flexor-hand-tenosynovitis-state-of-knowledge-a-study-of-120-cases
#14
REVIEW
William Mamane, Stenley Lippmann, Dan Israel, Reeta Ramdhian-Wihlm, Michael Temam, Virginie Mas, Jérome Pierrart, Emmanuel H Masmejean
Introduction: Since Kanavel in 1905, knowledge of phlegmon of flexor tendon sheaths of the fingers have evolved over the twentieth century. This serious infection is 20% of infections of the hand and may have adverse consequences for the function of the finger and even beyond, of the hand. Amputation is always a risk. Frequently face this type of infection, we conducted a retrospective study and made an inventory of knowledge in order to consolidate and improve the overall care. Materials & Methods: The study was retrospective and cross, focused on 120 patients operated on at Hand Surgery Unit, during 4 years...
June 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29880418/-perianal-abscess-in-children-a-pediatric-infectious-disease-perspective
#15
Sevgen Tanır Basaranoglu, Yasemin Ozsurekci, Ali Bulent Cengiz, Eda Karadag Oncel, Kubrac Aykac, Ates Kara, Mehmet Ceyhan
INTRODUCTION: There are limited data on the aetiology and management of perianal abscesses (PAs). The aim of this retrospective study was to define the characteristics of children with PAs; describe our experience with PA from the perspective of paediatric infectious medicine and determine the factors that influence clinical outcomes. METHODS: We performed a retrospective review of cases of PA in children with no underlying disease managed in a tertiary referral hospital between January 2005 and July 2015...
June 4, 2018: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29872681/utility-of-international-store-and-forward-teledermatopathology-among-a-cohort-of-mostly-female-patients-at-a-tertiary-referral-center-in-afghanistan
#16
A Ismail, J R McMichael, B K Stoff
Background: The variety and complexity of dermatologic diseases in Afghanistan and the associated diagnostic resource constraints have not been previously studied. Moreover, the utility of store-and-forward teledermatopathology in this resource-limited setting has not been investigated. Methods: A retrospective analysis was conducted of 150 store-and-forward teledermatopathology cases that were composed of a clinical history, clinical images, and histologic images that were sent from an academic teaching hospital in Kabul to a dermatology-trained dermatopathologist at Emory University in the United States between November 2013 and June 2017...
June 2018: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/29869797/ribavirin-for-treating-crimean-congo-haemorrhagic-fever
#17
REVIEW
Samuel Johnson, Nicholas Henschke, Nicola Maayan, Inga Mills, Brian S Buckley, Artemisia Kakourou, Rachel Marshall
BACKGROUND: Crimean Congo haemorrhagic fever (CCHF) is a tick-borne disease that occurs in parts of Asia, Europe and Africa. Since 2000 the infection has caused epidemics in Turkey, Iran, Russia, Uganda and Pakistan. Good-quality general supportive medical care helps reduce mortality. There is uncertainty and controversy about treating CCHF with the antiviral drug ribavirin. OBJECTIVES: To assess the effects of ribavirin for treating people with Crimean Congo haemorrhagic fever...
June 5, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29869360/spectrum-of-illness-among-returned-australian-travellers-from-bali-indonesia-a-5-year-retrospective-observational-study
#18
Asma Sohail, Sarah L McGuinness, Rachel Lightowler, Karin Leder, Bismi Jomon, Christopher A Bain, Anton Y Peleg
BACKGROUND: Bali, Indonesia presents significant infectious and non-infectious health risks for Australian travellers. Understanding this spectrum of illnesses has the potential to assist clinicians in evaluating unwell returning travellers and guide provision of pre-travel advice. AIM: To describe the spectrum of illnesses seen in returned travellers from Bali. METHODS: Using a novel text mining approach, we performed a retrospective, observational study of all adult emergency department (ED) presentations to a metropolitan health service in Melbourne, from 2011-2015...
June 5, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29868617/clinically-prepared-veterinary-students-enhancing-veterinary-student-hands-on-experiences-and-supporting-hospital-caseload-using-shelter-medicine-program
#19
Jacob M Shivley, Wilson C Brookshire, Philip A Bushby, Kimberly A Woodruff
Referral-level medicine is important in the veterinary curriculum, however veterinary students also need a solid base knowledge of clinically relevant, routine surgical and diagnostic skills to be clinically prepared after graduation. Exposure to a referral-only, or primarily referral caseload, does not always provide veterinary students with the routine hands-on experiences and competencies expected by the American Veterinary Medical Association Council on Education, the Royal College of Veterinary Surgeons, the Australian Veterinary Boards Council, or prospective employers...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29868136/prevalence-of-family-history-of-autoimmune-disorders-in-juvenile-systemic-lupus-erythematosus
#20
Parisa Ashournia, Payman Sadeghi, Nima Rezaei, Mohammad-Hassan Moradinejad, Vahid Ziaee
One of the causes of infants' hospitalizations is bronchiolitis, while different viral agents could be causative agents. As there is little information regarding the common agents of bronchiolitis in Iranian infants, we designed this study to determine which agents were responsible for hospitalization due to bronchiolitis among infants in an Iranian tertiary center. Two hundred and three infants with bronchiolitis who were hospitalized in Bahrami hospital were enrolled. Data regarding age, sex, duration of hospitalization, exposure to smoking, previous antibiotic usage and fever were collected for all enrolled cases...
March 2018: Mædica
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